• 제목/요약/키워드: segregational stability toxin-antitoxin system

검색결과 1건 처리시간 0.016초

Genetic Characterization of Two Putative Toxin-Antitoxin Systems on Cryptic Plasm ids from Bacillus thuringiensis Strain YBT-1520

  • Liu, Xiaojin;Zhu, Shufang;Ye, Weixing;Ruan, Lifang;Yu, Ziniu;Zhao, Changming;Sun, Ming
    • Journal of Microbiology and Biotechnology
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    • 제18권10호
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    • pp.1630-1633
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    • 2008
  • A novel putative toxin-antitoxin segregational stability system named KyAB system was identified in a novel native plasmid pBMB8240 from Bacillus thuringiensis strain YBT-1520, based on sequences homology with other toxin-antitoxin systems, the lethal activity of the KyB putative toxin in Escherichia coli and the stabilizing effect of the kyAB system in Bacillus thuringiensis. Secondarily, the native plasmid pBMB9741 from the same strain was resequenced and the corrected plasmid was named as pBMB7635. Based on sequence homology with the tasAB system and the lethal activity of toxin protein in Escherichia coli, a tasAB-like putative toxin-antitoxin system was identified on pBMB7635.