• Title/Summary/Keyword: second primary

Search Result 1,898, Processing Time 0.031 seconds

Incidence and Clinicopathologic Features of Primary Lung Cancer: A North-Eastern Anatolia Region Study in Turkey (2006-2012)

  • Demirci, Elif;Daloglu, Ferah;Gundogdu, Cemal;Calik, Muhammet;Sipal, Sare;Akgun, Metin
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.3
    • /
    • pp.1989-1993
    • /
    • 2013
  • Background: Lung cancer is the most frequent cancer among men and second highest among women overall, including in Turkey. Cigarette smoking is the most important etiologic factor for the development of cancer in both men and women. Objective: To determine the lung cancer incidence in Northeastern Anatolia Region of Turkey with a focus on clinical properties, cancer subtypes, the relationships of tumors with cigarette smoking and radiological properties of the lesions. Materials and Methods: In a retrospective study design, 566 lung cancer cases diagnosed at the Pathology Department of Ataturk University in Erzurum over the last seven years extending from January 2006 to June 2012 were investigated. The results were compared with statistical analyses. Results: The most common histopathological subtype of primary bronchogenic carcinoma in our study was found to be the squamous cell carcinoma, 46.1% (261 out of 566), and the second was small cell lung carcinoma 15.7% (89 out of 566). Based on our data, an overall male predominance was noted with a male/female ratio of 6.1/1. While 296 (52.2%) of the patients were found to be smokers at the time of diagnosis, 125 (22.0%) were nonsmokers and 145 (25.6%) were ex-smokers. Smoking status was found to have a strong correlation with primary lung cancer (p<0.05), and there were significant differences between males and females (p<0.001). Conclusion: Although relative prominence of subtypes of lung cancers differ between Turkish and other populations, lung cancer overall remains as an important health problem in Turkey. Our findings stress the critical need for effective cancer prevention programs such as anti-smoking campaigns.

The Effect of Having Usual Source of Care on the Choice among Different Types of Medical Facilities (상용치료원 보유가 의료기관 종별 선택에 미치는 영향: 대형병원 환자집중현상 완화방안을 중심으로)

  • Kim, Doo Ri
    • Health Policy and Management
    • /
    • v.26 no.3
    • /
    • pp.195-206
    • /
    • 2016
  • Background: Concentration of patients to large hospitals is serious problem in Korea. The purpose of this paper is to propose appropriate policy direction to relieve concentration of patients to large hospitals. It is focused on evaluation of the possibility of family doctor system as a policy alternative to relieve concentration of patients to large hospital by empirically analyzing the effect of usual source of care (USC) on large hospitals medical care use. Methods: Korea Health Panel conducted 2009, 2012, 2013 by KIHASA (Korea Institute for Health and Social Affairs) and NHIS (National Health Insurance Service) was used for analysis. For dependent variables, first, the ratio of the amount of using large hospital to total amount of using medical care, and second, the amount of using large hospital are estimated. Independent variables are having an USC and type of USC. Panel analysis was done with above variables. Results: Main results are as follows. First, having an USC increases using large hospital. Second, having a domestic clinic type USC decreases using large hospital and ratio of using large hospital. Third, the effect of domestic clinic type USC is greater in older group, less income group, worse health status group, not having private insurance group, and having chronic disease group. Conclusion: These results show that family doctor program can be a policy alternative to relieve concentration of patients to large hospital. Nonetheless, primary care system in Korea is unsatisfied. It is recommended to reinforce primary care system and family doctor system to relieve concentration of patients to large hospitals.

Motives for Moonlighting and Its Policy Implications (부업동기분석(副業動機分析)과 그 시사점(示唆點))

  • Park, Jin
    • KDI Journal of Economic Policy
    • /
    • v.14 no.4
    • /
    • pp.107-121
    • /
    • 1992
  • Moonlighting or second-jobs will increase shirking of the primary job. This paper analyzes the motives for moonlighting so that the means of reducing these motives could be explored. The traditional theory claims that a worker who cannot fully realize his work potential will look to moonlighting. In a two-period model, however, the following motives are more important. The precautionary savings motive : A worker has an incentive to save for fear of losing his job and his income in the second period. The worker could save more by working more during the first period, and this additional motive for working is the precautionary savings motive. The insurance motive : When a worker is unemployed, he cannot expand his moonlighting hours according to his needs since the moonlighting hour is upward rigid. Therefore, a worker has an incentive to secure additional moonlighting hours in the first period so that quick adjustment can be made during the unemployment in the second period. Two policy measures to remove those motives for moonlighting are recommended, for these measures will enhance the productivity in the primary job. First, a firm should guarantee that there will be no layoffs in a downturn in the economy and that the employment level is adjusted to the economic states by work sharing among workers. Second, as unemployment insurance benefits compensate a portion of the income in case of unemployment, it substitutes the motives for moonlighting. A generalization of this argument can be found in Ehrlich and Becker(1972) where self-insurance(moonlighting) and market insurance(in this case, unemployment insurance) serves as substitutes. The two policy measures in the above have a spill-over effect : A decrease of labor supply in the moonlighting market will ease job search, and therefore will help those who have their primary job in the moonlighting sector.

  • PDF

Advanced analysis for planar steel frames with semi-rigid connections using plastic-zone method

  • Nguyen, Phu-Cuong;Kim, Seung-Eock
    • Steel and Composite Structures
    • /
    • v.21 no.5
    • /
    • pp.1121-1144
    • /
    • 2016
  • This paper presents a displacement-based finite element procedure for second-order distributed plasticity analysis of planar steel frames with semi-rigid beam-to-column connections under static loadings. A partially strain-hardening elastic-plastic beam-column element, which directly takes into account geometric nonlinearity, gradual yielding of material, and flexibility of semi-rigid connections, is proposed. The second-order effects and distributed plasticity are considered by dividing the member into several sub-elements and meshing the cross-section into several fibers. A new nonlinear solution procedure based on the combination of the Newton-Raphson equilibrium iterative algorithm and the constant work method for adjusting the incremental load factor is proposed for solving nonlinear equilibrium equations. The nonlinear inelastic behavior predicted by the proposed program compares well with previous studies. Coupling effects of three primary sources of nonlinearity, geometric imperfections, and residual stress are investigated and discussed in this paper.

Numerical Algorithm for Power Transformer Protection

  • Park, Chul-Won;Suh, Hee-Seok;Shin, Myong-Chul
    • KIEE International Transactions on Power Engineering
    • /
    • v.4A no.3
    • /
    • pp.146-151
    • /
    • 2004
  • The most widely used primary protection for the internal fault detection of the power transformer is current ratio differential relaying (CRDR) with harmonic restraint. However, the second harmonic component could be decreased by magnetizing inrush when there have been changes to the material of the iron core or its design methodology. The higher the capacitance of the high voltage status and underground distribution, the more the differential current includes the second harmonic during the occurrence of an internal fault. Therefore, the conventional second harmonic restraint CRDR must be modified. This paper proposes a numerical algorithm for enhanced power transformer protection. This algorithm enables a clear distinction regarding internal faults as well as magnetizing inrush and steady state. It does this by analyzing the RMS fluctuation of terminal voltage, instantaneous value of the differential current, RMS changes, harmonic component analysis of differential current, and analysis of flux-differential slope characteristics. Based on the results of testing with WatATP99 simulation data, the proposed algorithm demonstrated more rapid and reliable performance.

Radiation induced secondary malignancies: a review article

  • Dracham, Chinna Babu;Shankar, Abhash;Madan, Renu
    • Radiation Oncology Journal
    • /
    • v.36 no.2
    • /
    • pp.85-94
    • /
    • 2018
  • Radiation-induced second malignancies (RISM) is one of the important late side effects of radiation therapy and has an impact on optimal treatment decision-making. Many factors contribute to the development of RISM such as age at radiation, dose and volume of irradiated area, type of irradiated organ and tissue, radiation technique and individual and family history of cancer. Exact mechanism of RISM is unknown. But nowadays, it is a growing concern in oncology because of the increased number of cancer survivors and efforts are being made to prevent or decrease the incidence of RISM. The primary search for articles was carried via Google Scholar and PubMed with keywords included 'radiation induced malignancies, second malignancies, and chemotherapy induced malignancies'. Additional papers were found through references from relevant articles. In this review article, we have discussed about the pathogenesis, factors contributing to RISM, screening and prevention strategies of RISM.

Expediting venous drainage in large anterolateral thigh flaps for scalp electrical burns in India: two case reports on the use of primary vein grafts for second vein anastomosis

  • Jyotica Jagadish Chawaria;Parvati Ravula;Nazia Tabassum;Srikanth Rangachari
    • Journal of Trauma and Injury
    • /
    • v.36 no.4
    • /
    • pp.404-410
    • /
    • 2023
  • Large scalp defects resulting from high-voltage electrical burns require free flaps, preferably skin, to permit optimal coverage and enable future or simultaneous cranial vault reconstruction. The anterolateral thigh permits the harvest of a large area of skin supplied by a reliable perforator. The superficial temporal vessels offer the proximate choice of recipient vessels to enable adequate reach and coverage. The lack of a second vein at this site implies the inability to perform a second venous anastomosis; however, this obstacle can be overcome by using an interposition vein graft, to the neck veins primarily. This assures adequate venous drainage and complete flap survival.

ANALYSIS OF RAYLEIGH-BENARD NATURAL CONVECTION (Rayleigh-Benard 자연대류 유동 해석)

  • Choi, Seok-Ki;Kim, Seong-O
    • Journal of computational fluids engineering
    • /
    • v.13 no.3
    • /
    • pp.62-68
    • /
    • 2008
  • This paper reports briefly on the computational results of a turbulent Rayleigh-Benard convection with the elliptic-blending second-moment closure (EBM). The primary emphasis of the study is placed on an investigation of accuracy and numerical stability of the elliptic-blending second-moment closure for the turbulent Rayleigh-Benard convection. The turbulent heat fluxes in this study are treated by the algebraic flux model with the temperature variance and molecular dissipation rate of turbulent heat flux. The model is applied to the prediction of the turbulent Rayleigh-Benard convection for Rayleigh numbers ranging from Ra=$2{\times}10^6$ to Ra=$10^9$ and the computed results are compared with the previous experimental correlations, T-RANS and LES results. The predicted cell-averaged Nusselt number follows the correlation by Peng et al.(2006) (Nu=$0.162Ra^{0.286}$) in the 'soft' convective turbulence region ($2{\times}10^6{\leq}Ra{\leq}4{\times}10^7$) and it follows the experimental correlation by Niemela et al. (2000) (N=$0.124Ra^{0.309}$) in the 'hard' convective turbulence region ($10^8{\leq}Ra{\leq}10^9$) within 5% accuracy. This results show that the elliptic-blending second-moment closure with an algebraic flux model predicts very accurately the Rayleigh-Benard convection.

ANALYSIS OF RAYLEIGH-BENARD NATURAL CONVECTION WITH THE SECOND-MOMENT TURBULENCE MODEL (이차모멘트 난류모델을 사용한 Rayleigh-Benard 자연대류 유동 해석)

  • Choi, Seok-Ki;Kim, Seong-O
    • 한국전산유체공학회:학술대회논문집
    • /
    • 2008.03a
    • /
    • pp.111-117
    • /
    • 2008
  • This paper reports briefly on the computational results of a turbulent Rayleigh-Benard convection with the elliptic-blending second-moment closure (EBM). The primary emphasis of the study is placed on an investigation of accuracy and numerical stability of the elliptic-blending second-moment closure for the turbulent Rayleigh-Benard convection. The turbulent heat fluxes in this study are treated by the algebraic flux model with the temperature variance and molecular dissipation rate of turbulent heat flux. The model is applied to the prediction of the turbulent Rayleigh-Benard convection for Rayleigh numbers ranging from $Ra=2{\times}10^6$ to $Ra=10^9$, and the computed results are compared with the previous experimental correlations, T-RANS and LES results. The predicted cell-averaged Nusselt number follows the correlation by Peng et al.(2006) ($Nu=0.162Ra^{0.286}$) in the 'soft' convective turbulence region ($2{\times}10^6{\leq}Ra{\leq}4{\times}10^7$) and it follows the experimental correlation by Niemela et al. (2000) ($Nu=0.124Ra^{0.309}$) in the 'hard' convective tubulence region ($10^8{\leq}Ra{\leq}10^9$) within 5% accuracy. This results show that the elliptic-blending second-moment closure with an algebraic flux model predicts very accurately the Rayleigh Benard convection.

  • PDF

Incidence and Significance of Multiple Primary Malignant Neoplasms (다발성 원발성 악성 종양 - 121 예의 임상적 분석-)

  • Choi Eun Kyung;Cho Moon June;Ha Sung Whan;Park Charn Il;Bang Young Ju;Kim Noe Kyung
    • Radiation Oncology Journal
    • /
    • v.4 no.2
    • /
    • pp.129-133
    • /
    • 1986
  • To know the three questions about multiple primary cancers: 1) what are the characteristics of persons having multiple parimary cancer? 2) Does the presence of a single primary concer after the susceptability to multiple primary cancers? 3) Does the location of one multiple primary cancer influence the site of others?, we analysed 121 cases of multiple primary malignant neoplasms registered in Seoul National University Hospital during 8 years from July 1978 to August 1986. Of 121 cases, double primary malignant neoplasms were 119 cases and triples were 2 cases. The incidence of multiple primary malignant neoplasms was $0.7\%$. The metachronous tumor (>6 months) was found in 70 cases and the median time between the first and the second was 32 months. The most commonly associated tumors were stomach and primary liver carcinoma. Cervix and Lung cancer, Stomach and Rectal cancer, Stomach and Esophagus cancer were also commonly associated.

  • PDF