• The KIPS Transactions:PartD
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• v.14D no.3 s.113
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• pp.347-354
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• 2007

It is not easy for the customers to search the valuable information on the goods among countless items available in the Internet. In order to save time and efforts in searching the goods the customers want, it is very important for a recommender system to have a capability to predict accurately customers' preferences. In this paper we present a refined neighbor selection algorithm for clustering based collaborative filtering in recommender systems. The algorithm exploits a graph approach and searches more efficiently for set of influential customers with respect to a given customer; it searches with concepts of weighted similarity and ranked clustering. The experimental results show that the recommender systems using the proposed method find the proper neighbors and give a good prediction quality.

• Korean Journal of Microbiology
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• v.42 no.1
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• pp.77-81
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• 2006

Degenerate primers corresponding to the sequences of the N-terminal regions of Mn-peroxidase isozymes were used to isolate the genomic fragments encoding the isozymes of Mn-peroxidase, CVMP1, CVMP2, CVMP3 and CVMP5 from the white-rot fungus Trametes versicolor KN9522. Three isozymes except one gave the expected PCR products (cmp1, cmp2 and cmp5) of about 900 base pairs, respectively. DNA sequence data obtained from each PCR products were used to analyze the BLAST program search on the National Center for Biotechnology Information. cmp1, cmp2 and cmp5 were similar to MPG-I (GenBank accession number Z30668) and PGV-II (GenBank accession number, Z54279) gene T. versicolor PRL572. PCR products of cmp1 and cmp2 showed 77%, 95% base sequence similarities to MPG-I gene and cmp5 showed about 88% similarity to PGV-II gene from T. versicolor PRL572. From this experiment, we could isolate genomic DNA fragments with degenerate primers designed from the N-terminal amino acid sequences of Mn-peroxidase isozyme family.

• Journal of Digital Convergence
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• v.16 no.3
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• pp.303-309
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• 2018

Computer vision technology is a component inspection to obtain a video image from the camera to the machine to perform the capabilities of the human eye with a field of artificial intelligence, and then analyzed by the algorithm to determine to determine the good and bad of production parts It is widely applied. Shape inspection method was used as how to identify the location of the start point and the end point of the search range, measure the height to the line scan method, in such a manner as to determine the presence or absence of the bolt tabs average brightness of the inspection area in a circular scan type value And the degree of similarity was calculated. The total time it takes to test in the test performance tests of two types of bolts tab enables test 300 min, and demonstrated the accuracy and efficiency of the inspection on the production line represented a complete inspection accuracy.

• BMB Reports
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• v.40 no.3
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• pp.349-357
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• 2007

The ubiquitous family of 14-3-3 proteins functions as regulators in a variety of physiological processes. Eight rice 14-3-3 genes, designated OsGF14a through h, were identified from an exhaustive search of the genome database. Comparisons of deduced amino acid sequences reveal a high degree of identity among members of the OsGF14 family and reported Arabidopsis 14-3-3 proteins. A phylogenetic study indicates that OsGF14s contain both $\varepsilon$ and non-$\varepsilon$ forms, which is also confirmed by a structural analysis of OsGF14 genes. Furthermore, transcripts of OsGF14b, OsGF14c, OsGF14d, OsGF14e, OsGF14f and OsGF14g were detected in rice tissues. Their different expression patterns, the different effects of environmental stresses and plant hormones on their transcription levels, and the different complementary phenotypes in yeast 14-3-3 mutants not only indicates that OsGF14s are responsive to various stress conditions and regulated by multiple signaling pathways, but also suggests that functional similarity and diversity coexist among the members of OsGF14 family.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3759-3765
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• 2015

Background: Approaches in disruption of MDM2-p53 interactions have now emerged as an important therapeutic strategy in resurrecting wild type p53 functional status. The present study highlights virtual screening strategies in identification of high affinity small molecule non-peptidic inhibitors. Nutlin3A and RG7112 belonging to compound class of Cis-imidazoline, MI219 of Spiro-oxindole class and Benzodiazepine derived TDP 665759 served as query small molecules for similarity search with a threshold of 95%. The query molecules and the similar molecules corresponding to each query were docked at the transactivation binding cleft of MDM2 protein. Aided by MolDock algorithm, high affinity compound against MDM2 was retrieved. Patch Dock supervised Protein-Protein interactions were established between MDM2 and ligand (query and similar) bound and free states of p53. Compounds with PubCid 68870345, 77819398, 71132874, and 11952782 respectively structurally similar to Nutlin3A, RG7112, Mi219 and TDP 665759 demonstrated higher affinity to MDM2 in comparison to their parent compounds. Evident from the protein-protein interaction studies, all the similar compounds except for 77819398 (similar to RG 7112) showed appreciable inhibitory potential. Of particular relevance, compound 68870345 akin to Nutlin 3A had highest inhibitory potential that respectively showed 1.3, 1.2, 1.16 and 1.26 folds higher inhibitory potential than Nutilin 3A, MI 219, RG 7112 and TDP 1665759. Compound 68870345 was further mapped for structure based pharamacophoric features. In the study, we report Cis-imidazoline derivative compound; Pubcid: 68870345 to have highest inhibitory potential in blocking MDM2-p53 interactions hitherto discovered.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.131-131
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• 2017

Though the Platycodon grandiflorum, has a broad range of pharmacologic properties, but the mechanisms underlying these effects remain unclear. In order to profile proteins from the nodal segment, callus, root and shoot, high throughput proteome approach was executed in the present study. Two-dimensional gels stained with CBB, a total of 84 differential expressed proteins were confirmed out of 839 protein spots using image analysis by Progenesis SameSpot software. Out of total differential expressed spots, 58 differential expressed protein spots (${\geq}2-fold$) were analyzed using MASCOT search engine according to the similarity of sequences with previously characterized proteins along with the UniProt database. Out of 58 differential expressed protein, 32 protein spots were up-regulated such as ribulose-1,5-bisphosphate carboxylase, endoplasmic oxidoreductin-1, heat stress transcription factor A3, RNA pseudourine synthase 4, cysteine proteinase, GntR family transcriptional regulator, E3 xyloglucan 6-xylosyltransferase, while 26 differential protein spots were down-regulated such as L-ascorbate oxidase precursor, late embryogenesis abundant protein D-34, putative SCO1 protein, oxygen-evolving enhancer protein 3. However, the frequency distribution of identified proteins using iProClass databases, and assignment by function based on gene ontology revealed that the identified proteins from the explants were mainly associated with the nucleic acid binding (17%), transferase activity (14%) and ion binding (12%). Taken together, the protein profile may provide insight clues for better understanding the characteristics of proteins and its metabolic activities in various explants of this essential medicinal plant P. grandiflorum.

• Science of Emotion and Sensibility
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• v.10 no.1
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• pp.37-47
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• 2007

Color planning system can be treated as a decision support system which includes both the recommendation of main color and harmonious colors. In this paper, we propose techniques that are useful to enhance the harmonious color recommendation with the main color selected by user. In order to reflect the knowledge about suggestion of harmonious colors, we use Ostwald color harmony theory, that is very systematical and easy to implement. Actually, Ostwald color space is similar to HMMD color model in MPEG-7. Due to the similarity between two color spaces, Ostwald color space can be represented as a virtual HMMD color space. Accordingly, we propose a technique to align the HMMD color space with Ostwald color space, thereby it is capable of enhancing a performance to search the harmonious colors according to Ostwald harmony theory. For recommendation of delicate and more exquisite harmonious colors in equal hue plane, we made the virtual color space continuous. The system can recommend various harmonious colors according to Ostwald color harmony. He(she) can select harmonious colors among the suggestions from the system.

• The KIPS Transactions:PartD
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• v.10D no.1
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• pp.57-66
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• 2003

With the development of the internet and computer, the amount of information through the internet is increasing rapidly and it is managed in document form. For this reason, the research into the method to manage for a large amount of document in an effective way is necessary. The document clustering is integrated documents to subject by classifying a set of documents through their similarity among them. Accordingly, the document clustering can be used in exploring and searching a document and it can increased accuracy of search. This paper proposes an efficient incremental cluttering method for a set of documents increase gradually. The incremental document clustering algorithm assigns a set of new documents to the legacy clusters which have been identified in advance. In addition, to improve the correctness of the clustering, removing the stop words can be proposed and the weight of the word can be calculated by the proposed TF$\times$NIDF function.

• The KIPS Transactions:PartD
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• v.10D no.1
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• pp.133-142
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• 2003

The major challenge for post-genomic study is to identify structural similarity and relationships of proteins. SCOP (Structural Classification of Proteins) is a typical database for this purpose, providing a derailed description of the structural and functional relationships of the proteins whose three-dimensional structures have been determined. Unfortunately, since the SCOP data is only available as a plain text format, it is cumbersome and error-prone to develop tools and resources to utilize the data more effectively. To meet these researchers to utilize the data more effectively. To meet these requirements, we have developed an XML representation for the SCOP site, users of the tool, named, SCOPBrowser, for effective search of SCOP database. In addition to the information available from the SCOP site, users of the tool can obtain various information such as viewing the tree hierarchy of structure classification of proteins, searching into whole protein domains, showing XML contents of a specific domain, and some useful statistics about protein structures.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38B no.4
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• pp.291-297
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• 2013

Recently, the amount of web pages, which include various information, has been drastically increased according to the explosive increase of WWW usage. Therefore, the need for web page classification arose in order to make it easier to access web pages and to make it possible to search the web pages through the grouping. Web page classification means the classification of various web pages that are scattered on the web according to the similarity of documents or the keywords contained in the documents. Web page classification method can be applied to various areas such as web page searching, group searching and e-mail filtering. However, it is impossible to handle the tremendous amount of web pages on the web by using the manual classification. Also, the automatic web page classification has the accuracy problem in that it fails to distinguish the different web pages written in different forms without classification errors. In this paper, we propose the automatic web page classification system using meta-tag that can be obtained from the web pages in order to solve the inaccurate web page retrieval problem.