• The Korean Journal of Physiology and Pharmacology
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• v.19 no.4
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• pp.319-325
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• 2015

Among solute carrier proteins, the organic anion transporters (OATs) play an important role for the elimination or reabsorption of endogenous and exogenous negatively charged anionic compounds. Among OATs, SLC22A9 (hOAT7) transports estrone sulfate with high affinity. The net decrease of estrogen, especially in post-menopausal women induces rapid bone loss. The present study was performed to search the SNP within exon regions of SLC22A9 in Korean females with osteoporosis. Fifty healthy controls and 50 osteoporosis patients were screened for the genetic polymorphism in the coding region of SLC22A9 using GC-clamped PCR and denaturing gradient gel electrophoresis (DGGE). Six SNPs were found on the SLC22A9 gene from Korean women with/without osteoporosis. The SNPs were located as follows: two SNPs in the osteoporosis group (A645G and T1277C), three SNPs in the control group (G1449T, C1467T and C1487T) and one SNP in both the osteoporosis and control groups (G767A). The G767A, T1277C and C1487T SNPs result in an amino acid substitution, from synonymous vs nonsynonymous substitution arginine to glutamine (R256Q), phenylalanine to serine (F426S) and proline to leucine (P496L), respectively. The Km values and Vmax of the wild type, R256Q, P496L and F426S were 8.84, 8.87, 9.83 and $12.74{\mu}M$, and 1.97, 1.96, 2.06 and 1.55 pmol/oocyte/h, respectively. The present study demonstrates that the SLC22A9 variant F426S is causing inter-individual variation that is leading to the differences in transport of the steroid sulfate conjugate (estrone sulfate) and, therefore this could be used as a marker for certain disease including osteoporosis.

• The KIPS Transactions:PartB
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• v.15B no.1
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• pp.9-16
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• 2008

In this paper, we present an algorithm for synthesizing intermediate view image from a stereoscopic pair of images. An image of multiview is need for people in order to easily recognize 3D image. However, if many cameras are use for that, not only does system get more complicated but also transmission rating cause a big trouble. Hence, stereo images are photograph and issue on the sending side and algorithm to generate several intermediate view image is able to be use on the receiving side. The proposed method is based on disparity space image. First of all, disparity space image that is depicted by the gap of pixel followed by disparity of stereo image is generated. Disparity map is made by utilizing disparity space image for searching for optimal disparity path then eventual intermediate view image is generated after occlusion region which does not match is processed. Experimental results illustrate the performance of the proposed technique and we obtained a high quality image of more than 30 dB PSNR.

• Archives of Plastic Surgery
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• v.47 no.1
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• pp.3-8
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• 2020

Genital lymphedema (GL) is an uncommon and disabling disease that manifests as enlargement of the genital region resulting from the disturbance of lymphatic drainage. Although conservative treatment such as decompression is typically the first-line approach, surgical intervention has been shown to be effective in certain cases. This study aimed to systematically review studies evaluating available surgical alternatives for the treatment of male GL. A systematic search strategy using keyword and subject headings was applied to PubMed, Scopus, EMBASE, and Cochrane Library in May 2019. Studies investigating various surgical techniques to treat penile and scrotal lymphedema were included. The potential risk of bias of included trials was evaluated using the methodological index for non-randomized studies (MINORS). In total, 13 studies met the inclusion criteria, nine of which were determined to be high-quality. The average MINORS score was 12.45 for studies involving excision and 14 for studies involving lymphovenous anastomosis (LVA). The most common reason for a low score was a failure to describe the inclusion criteria. Recurrence of lymphedema during follow-up was reported in four studies involving excision and in no studies involving LVA. In general, the quality of the included literature was considered to be fair. Although surgical intervention might not always prevent the recurrence of lymphedema, all of the studies reported improved quality of life after the procedure. This study could be used as the basis for evidence-based guidelines to be applied in clinical practice for managing male GL.

• The Korean Journal of Mycology
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• v.26 no.3 s.86
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• pp.314-320
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• 1998

A 0.4 kb cDNA fragment was isolated from mRNA of UV or mechanical wound damaged Pleurotus sajor-caju by the differential display method. Expression of the gene corresponding to this cDNA fragment was highly induced by mechanical wound damage or UV treatment. This gene showed only basal level expression in mycelia, stipe, and cap under normal growth conditions. Sequencing analysis showed that this cDNA fragment contains partial open reading frame. Homology search using genbank database revealed that although this gene do not have homology with already reported wound induced genes, it has a significant sequence homology in defined region with the cdc2-related protein kinase gene which is known to be involved in negative regulation of meiotic maturation in Xenopus oocytes.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.9
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• pp.889-897
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• 2010

Recently, a cutting-edge large-scale image database system has demanded these attributes: search with alarming speed, performs with high accuracy, archives efficiently and much more. An image identifier (descriptor) is for measuring the similarity of two images which plays an important role in this system. The extraction method of an image identifier can be roughly classified into two methods: a local and global method. In this paper, the proposed image identifier, LFH(Local Feature's Histogram), is obtained by a histogram of robust and distinctive local descriptors (features) constrained by a district sub-division of a local region. Furthermore, LFH has not only the properties of a local and global descriptor, but also can perform calculations at a magnificent clip to determine distance with pinpoint accuracy. Additionally, we suggested a way to extract LFH via GPU (OpenGL and GLSL). In this experiment, we have compared the LFH with SIFT (local method) and EHD (global method) via storage capacity, extraction and retrieval time along with accuracy.

• Korean Journal of Social Welfare Studies
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• no.37
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• pp.399-427
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• 2008

The purpose of this study is to examine the moderating effects of protective factors on the relations between deviant peer's influences and delinquent behaviors in adolescence. To investigate the moderating effects, simple slope and region of significance test based on multiple linear regression(MLR) model were used. This study used data from wave 1-2(2003-2004) of the Korea Youth Panel Survey(KYPS). Results showed that for female adolescents, self-esteem, parent monitoring, and attachment to parent moderated the link between best friend's deviancy and delinquent behaviors. For male adolescents, however, best friend's deviancy and protective factors didn't show any significant moderating effects. These results help clarify the conditions under which exposure to deviant best friends can influence delinquent behaviors in adolescence. Practice and policy implications as well as further research topic were discussed to aid the search for highly effective preventive and treatment interventions.

• Journal of the Korean Society of Marine Environment & Safety
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• v.12 no.3 s.26
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• pp.219-224
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• 2006

In this study, the risk of SRRs was assessed upon the scale of the damage of marine accidents. For the risk assessment, inner-outer dependence methods and special knowledge-based fuzzy logic were introduced. Also, in order to calculate the importance of assessment value in this study, a max-min composition method was used for fuzzy logic based on the principle of fuzzy extension and the centroid of gravity method was used for non-fuzzy formation. In order to produce the importance of assessment items, the inner-outer dependence methods were used for assessment items, and markov analysis method was used for the importance of the final comprehensive assessment. As a result, the risk of SRR of Tongyoung, Mokpo and Yeosu was proven relatively higher, thus, it needs to have more rescue ships and rescue devices for relieving the risk in the future.

• Journal of Oral Medicine and Pain
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• v.46 no.3
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• pp.75-83
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• 2021

Odontogenic infection in the oral and maxillofacial regions caused by bacteria (mostly of oral origin) is one of the most common diseases encountered by dentists. Localized infection can easily be treated with incision and drainage followed by antibiotics. Emergence of multidrug resistant (MDR) bacteria called "Superbacteria" has become one of the serious problems in modern society, due to its small window of opportunity for treatment and high casualty. The acronym "ESKAPE", encompassing the common and serious MDR pathogens stand for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp. Literature search was performed in Medline, PubMed and Google Scholar ranging from 2012 to 2020. ESKAPE patient's infection period was longer than that of non-ESKAPE group, and the treatment method due to antibiotic resistance was also complicated. The purpose of this study is to investigate infection caused by ESKAPE pathogens in the oral and maxillofacial regions through literature review and to inform dental surgeons of the danger of ESKAPE pathogens and to suggest viable treatment options. Many studies worldwide reported infections associated with ESKAPE pathogens, but only limited number of studies targeted infection in oral and maxillofacial regions. Further research is required with more data on ESKAPE bacteria and their infection, especially in oral and maxillofacial regions.

• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.1-9
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• 2019

The purposes of the study are to investigate Koreans' perception about Vietnam by analyzing social big data and to seek changing direction in perception. For the purposes, the texts about Vietnam in Naver Blog and Twitter and the number of search and click for Vietnam in Naver were analyzed by Social Metrics of Daum Soft and Datalab of Naver. The study also analyzed the annual change of their interest in Vietnam based on social media. The results showed that Koreans still remember the Vietnam war, have a positive emotion toward Vietnam, and view Vietnam as a country where we can gain mutual benefit by exchange. The findings also indicated that Koreans perceive Vietnam as a favorite tourist spot regardless of age. Meanwhile, children under 12 showed a different pattern of an annual change in perception. It might be a positive sign that Koreans' interest region toward Vietnam would be diversified because children under 12 would be the central axis of cultural contents.

• Journal of Engineering Education Research
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• v.21 no.6
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• pp.99-107
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• 2018

The purpose of this study is to establish and propose educational vision of chemical engineering field in order to search for academic identity and future education direction in chemical engineering field. In order to achieve this research purpose, we investigate the literature and data on the vision, educational goals, and curriculum of the department of chemical engineering in domestic and foreign universities. We also analyze the SWOT of internal and external environmental factors respectively. The validity of the proposal was verified through delphi survey with delphi panels and the vision was developed by revising and improving upon the opinions of professionals. The vision is comprised of the value and mission of learning, the educational purpose, and the educational goal. The first stage is value and mission of chemical engineering. The educational purposes and the educational goals are divided into 'Department of Chemical Engineering' and 'Department of Chemical and Biological Engineering'. The application of the educational vision of chemical engineering field is as follows. First, we expect that the vision to be a valuable, philosophical, and theoretical basis for establishing educational objectives and goals in the field of chemical engineering. Hopefully, it will be used as a general education goal for the top-level education. Second, we hope that the vision will be used to develop customized vision, customized educational purpose, and educational goals that reflect the characteristics of region, departments, graduates, and educational needs in the field of chemical engineering. Finally, we hope that these results will be the starting point to discuss the educational vision in the department of chemical engineering.