• 한국운동역학회지
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• 제26권3호
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• pp.323-331
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• 2016

Objective: The aims of this study were 1) to develop easy-to-use rhythmic balance training equipment for the elderly and 2) to investigate the effect of training with the equipment on balance and physical function. Method: Twenty-one elderly individuals (age: $75.4{\pm}3.34yrs$, height: $152.07{\pm}4.81cm$, weight: $58.35{\pm}8.34kg$) participated in this study. Each participant underwent balance and physical function testing before and after 12 weeks of training with the equipment. Y-balance (i.e. dynamic balance) and one leg static balance tests were used for balance testing, and timed up- and-down-stairs and five times sit-to-stand tests were used for physical function testing. A paired t test was used to determine whether there was a significant pre- and post-training difference. Results: The rhythmic balance training equipment provided a fun and motivating training program with age-friendly music, dance movements for lower extremity strength training, and touch screen controls with simple features. Post-training left foot dynamic balance was significantly greater (p<.05), and static balance with eyes open was significantly improved (p<.05) compared to pre-training. Completion of the timed up-and-down-stairs and the five times sit-to-stand tests was significantly shorter (p<.05) compared to pre-training. Conclusion: Training using the equipment developed in this study improved balance and physical function in elderly participants.

• 수면정신생리
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• 제6권2호
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• pp.149-157
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• 1999

정신과 임상에서 편리하게 사용할 수 있는 전산화 신경심리 검사 시스템을 개발하였다. 이 시스템은 뇌의 전반적인 인지 기능과 뇌의 기능적 국재화를 평가할 수 있는 14개의 신경심리 검사로 구성되어 있다. 개발된 시스템은 멀티미디어와 객체 지향 개념에 의해 설계, 구현되었고, 마이크로 소프트 Windows에 기반을 둔 그래픽 인터페이스를 채용하여 운용이 용이하도록 하였다. 또한 마우스와 터치 스크린을 이용하여 피검사자로부터 입력을 손쉽게 받아드릴 수 있도록 하였으며, 색채 단어 검사, 범주 검사, 그리고 언어 기억 검사, 언어 지각 검사 등은 한글화하여 검사의 효율성을 향상시켰다. 개발된 시스템을 뇌손상 환자와 정신과 환자에 적용한 결과 그 인지 장애와 뇌의 기능적 국재화를 평가하는데 유용하게 사용될 수 있었다.

• Neonatal Medicine
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• 제28권3호
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• pp.133-138
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• 2021

Osteopetrosis refers to a group of genetic skeletal disorders characterized by osteosclerosis and fragile bones. Osteopetrosis can be classified into autosomal dominant, autosomal recessive, or X-linked forms, which might differ in clinical characteristics and disease severity. Autosomal recessive osteopetrosis, also known as malignant osteopetrosis, has an earlier onset, more serious clinical symptoms, and is usually fatal. We encountered a 1-day-old girl who was born full-term via vaginal delivery, which was complicated by meconium-stained amniotic fluid, cephalo-pelvic disproportion, and nuchal cord. Routine neonatal care was provided, in addition to blood tests and chest radiography to screen for sepsis, as well as skull radiography to rule out head injuries. Initial blood tests revealed hypocalcemia, which persisted on follow-up tests the next day. Radiographic examinations revealed diffusely increased bone density and a "space alien" appearance of the skull. Based on radiographic and laboratory findings, the infantile form of osteopetrosis was suspected and genetic testing for identification of the responsible gene. Eventually, a heterozygous mutation of the T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 (TCIRG1) gene (c.292C>T) was identified, making this the first reported case of neonatal-onset malignant osteopetrosis with TCIRG1 mutation in South Korea. Early-onset hypocalcemia is common and usually results from prematurity, fetal growth restriction, maternal diabetes, perinatal asphyxia, and physiologic hypoparathyroidism. However, if hypocalcemia persists, we recommend considering 'infantile of osteopetrosis' as a rare cause of neonatal hypocalcemia and performing radiographic examinations to establish the diagnosis.

• 한국콘텐츠학회논문지
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• 제21권8호
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• pp.403-412
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• 2021

모바일 앱의 수가 기하급수적으로 늘어남에 따라 앱 개발과정에서 이루어지는 테스트의 자동화가 중요해지고 있다. 앱을 출시하기까지 다양한 유형의 테스트를 통해 반복적인 검증이 이루어지는데, 다양한 유형의 테스트 중 GUI 테스트를 중심으로 본 연구는 진행되었다. 안드로이드의 GUI 테스트 자동화 툴을 개발하기 위해서 안드로이드 앱 테스트의 UI Control 16가지와 Material Design Guideline에 대해서 기초 자료를 수집하였다. 그 후 기존 GUI 테스트 자동화 툴에 대해서 스크린 캡처 테스트 기반 2가지 툴과 소스코드 분석 테스트기반 4가지 툴 분석을 하였다. 분석을 통해 기존의 GUI 테스트 자동화 툴들은 시각적 설계, 인터페이스 사용 용이성, 컴포넌트 배치에 대해서는 고려하지 않고 있다는 점을 파악하였다. 이러한 기존 툴의 미비점을 보완하고자 새로운 GUI 테스트 자동화 툴 개발 방법으로 컴포넌트 선정이나 관리 분석 그리고 컴포넌트별 소스코드 예시로 탐색 메뉴나 버튼, 아이템 그룹화나 리스트에 관한 방법을 제시하였다. 본 연구는 GUI 테스트의 새로운 개발 방향을 제시함으로써 개발사의 안정적인 앱 배포에 기여할 수 있다는 점에서 의의가 있다.

• Clinical and Experimental Pediatrics
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• 제49권11호
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• pp.1167-1173
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• 2006

목 적 : 신생아 패혈증을 진단하기 위해 단독 그리고 복합적인 다양한 선별검사를 분석하기 위해 일신기독병원의 신생아집중치료실에서 2001년 4월 1일부터 2005년 12월 31일까지 68개월 동안 시행했다. 방 법 : 패혈증의 임상증상이 있는 100명의 신생아와 증상이 없는 정상 신생아를 대상으로 연구를 시행했다. 신생아 패혈증의 진단을 위해 CRP, 총 백혈구 수, 총 호중구 수, 미숙호중구/총호중구 비(I/T비), 혈소판 수, 호중구의 변성, 다형 핵 백혈구에 대한 GAC를 사용했다. 결 과 : CRP는 A군에서는 50례 중 40례에서(86%) 양성이었고 B군에서는 50례 중 37례에서(74%) 양성이었으며 특이도는 94%였다. 총 호중구 수는 민감도와 특이도가 각각 A군에서는 72%와 86%였고 B군에서는 62%와 86%로 단일 검사상 민감도가 두 번째로 높았다. A군에서 GAC와 혈소판 수에 대한 각각의 민감도는 74%와 64%였다. A군과 B군에 대해 검사를 개별적으로 시행했을 경우와 함께 시행했을 경우에 대한 민감도, 특이도, 그리고 예측도를 계산했다. 결 론 : CRP, 총 백혈구 수, 총 호중구 수, 혈소판 수, 호중구의 변성과 다형 핵 백혈구에 대한 GAC는 신생아 패혈증이 없는 배양 검사 상 음성인 경우를 알아내는데 높은 민감도를 나타냈다. 더욱이 3가지 검사를 함께 시행할 경우에 민감도가 증가했다.

• Toxicological Research
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• 제16권2호
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• pp.109-116
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• 2000

The purposes of our study were to optimize the conditions of the screening and testing methods for endocrine disruptors, to characterize these assays using several compounds with well-defined endocrine activity, and to compare the sensitivity between these assays currently undergoing validation. Two in vitro test systems, MCF-7 cells proliferation (E-screen assay) and competitive binding to estrogen receptors (ER) were selected to evaluate the estrogenic effects. 17$\beta$-Estradiol (E2) and diethylstilbestrol (DES) were used as a positive control in vitro test. Also, E2 and ethinyl estradiol (EE) were used as a positive control in vivo uterotrophic assay. In in vitro test, E2 and DES showed a strong estrogenic response at concentration of 1.0 nM. In uterotrophic assay, E2 (0.3 $\mu\textrm{g}$/kg) and EE (0.3 $\mu\textrm{g}$/kg) produced a significant increase in uterus and vagina weight in both immature and ovariectomized rats. Although we did not com-pared the specificity between in vivo and in vitro assays, these assay systems may serve as a good tool for endocrine disruptors screening methods. Our data indicate that these assay systems exhibit some difference in their sensitivity to the same estrogenic compounds. Therefore, as a first rapid screening assay for estrogenic activity qf unknown chemicals, at least two assay systems should probably be carried out with a view of high sensitivity and standardization conditions. Also, a careful validation tests are necessary to obtain a reasonable degree of reproducibility.

• Physical Therapy Rehabilitation Science
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• 제6권4호
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• pp.182-188
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• 2017

Objective: The purpose of this study was to compare ankle function between adults with and without Down syndrome (DS). Design: Cross-sectional study. Methods: Ten adults with DS and 18 without participated in this study and underwent manual muscle test (MMT), range of motion (ROM) assessment, star excursion balance test (SEBT), and functional movement screen (FMS). The tests were demonstrated to increase their accuracy and the actual measurements were assessed after one or two demonstrations. To minimize the standby time and fatigue, the travelled distance and measuring order were adjusted. To remove the influence of shoes on the measurements, the shoes were taken off and only socks were worn. Results: Dorsal and plantar flexion MMTs of both ankles were significantly weaker and plantar flexion ROM of both ankles were significantly lower in adults with DS compared with those without (p<0.05). However, dorsal flexion ROM of both ankles were not significantly different between them. There were significant differences in distances measured in all the directions (anterior, anterolateral, lateral, posterolateral, posterior, posteromedial, medial, and anteromedial directions) of SEBT (p<0.05). Significant differences were also demonstrated in the scores of hurdle step, inline lunge, shoulder mobility, and rotary stability among the seven items of FMS (p<0.05). Conclusions: To enhance the dynamic stability of adults with DS, it is necessary to improve ankle stability by strengthening the ankle dorsal and plantar flexors.

• 한국콘텐츠학회논문지
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• 제10권7호
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• pp.198-207
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• 2010

그림책화면에서 나타나는 시각적 의미형성은 전달하고자 하는 현상이나 메시지를 직접적으로 보여주는 것뿐만 아니라 다른 이미지를 더하거나 과장, 축소하여 대상의 속성이나 특성을 보다 쉽고 빠르게 이해시켜줄 수 있다는 점에서 독창적인 표현방법이 된다. 본 연구는 어린이그림책에서 나타나는 은유적 표현방식이 어린이에게 시각적 심리적으로 어떻게 작용하는지 분석하기 위하여 먼저, 시각적 은유특성과 표현형식에 대한 이론적 고찰을 통해 그림책일러스트레이션의 표현방법에 대한 범주화의 틀을 마련하였다. 또한 실증조사를 통해 어린이의 시각적 심리적 지각반응을 명확하게 도출하기 위하여 표현형식을 2가지 유형으로 구분하고, 이를 심층면접의 설문자료로 활용하여 유형별 어린이의 언어적 심리적 반응을 분석하였다. 끝으로 본 연구가 제시한 결론은 일러스트레이터의 개성과 창의성이 바탕이 된 화면제작에 도움이 됨은 물론, 일러스트레이션을 배우는 학생들에게 효과적인 표현방법연구와 실험에 활용될 것으로 사료된다.

• Safety and Health at Work
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• 제11권3호
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• pp.301-306
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• 2020

Background: The Functional Movement Screen (FMS^TM) is a screening tool used to assess an individual's ability to perform fundamental movements that are necessary to do physically active tasks. The purpose of this study was to assess the ability of FMS to predict occupational injury among Denver Fire Department firefighters. Method: FMS tests were administered from 2012 to 2016. Claim status was defined as any claim occurrence vs. no claim and an overexertion vs. no claim/other claim within 1 year of the FMS. To assess associations between FMS score and claim status, FMS scores were dichotomized into ≤ 14 and > 14. Age-adjusted odds ratios were calculated using logistic regression. Sensitivities and specificities of FMS predicting claims at various FMS score cut points, ranging from 10 to 20 were tested. Results: Of 581 firefighters (mean ± SD, age 38 ± 9.8 y) who completed FMS between February 2015 and March 2018, 188 (32.4%) filed a WC claim in the study time frame. Seventy-two of those (38.3%) were categorized as overexertion claims. There was no association between FMS score and claim status [odds ratio (OR) = 1.27, 95% confidence interval (CI): 0.88 - 1.83] and overexertion claim vs. no claim/other claim (OR = 1.33, 95% CI: 0.81 - 2.21). There was no optimal cutoff for FMS in predicting a WC claim. Conclusions: Although the FMS has been predictive of injuries in other populations, among this sample of firefighters, it was not predictive of a future WC claim.

• 대한인간공학회지
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• 제34권4호
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• pp.335-351
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• 2015

Objective: The aim of this study was to perform a usability test for CPAD (Cognitive Perceptual Assessment for Driving) and improve it based on the test results. Background: The cognitive perceptual assessment for driving is a computer-based assessment tool to assess the driving capacity of people with brain-damages. It may be a good tool for evaluating the brain-damaged drivers' safe driving capabilities and screening cognitive and perceptual deficits related to driving. We performed a usability test to improve the CPAD based on the result. Method: Both the software consisting of 8 sub-tests (depth perception, sustained attention, divided attention, stroop test, field dependency, digit span, trail making A, trail making B) and the hardware including the input and output devices ( joystick, mouse, keyboard, touch screen) were evaluated through user interviews. Also we identified the problems and issues in using them by observing the participants performing the CPAD tasks. Results: Based on the results, the task instructions were visually and auditorily improved and more practice examples were added to help the users understand the instructions better and increase the input accuracy, a response time window was added and the joystick and touch screen were simplified, which made it easier for the user to perform the CAPD tasks. Conclusion: User discomforts were minimized by improving the task environment, unless it had affected the evaluation criteria. Application: We plan to distribute the improved version of the CPAD to the regional rehabilitation hospitals, and the driving support centers for people with disabilities throughout the country, so it could be used as an evaluation tool for disabled drivers' cognitive and perceptual functions.