• Analytical Science and Technology
• /
• v.24 no.6
• /
• pp.544-555
• /
• 2011

The acute toxicity in the rainbow trout (Oncorhynchus mykiss) was analyzed and predicted using quantitative structure-activity relationships (QSAR). The aquatic toxicity, 96h $LC_{50}$ (median lethal concentration) of 275 organic pesticides, was obtained from EU-funded project DEMETRA. Prediction models were derived from 558 2D molecular descriptors, calculated in PreADMET. The linear (multiple linear regression) and nonlinear (support vector machine and artificial neural network) learning methods were optimized by taking into account the statistical parameters between the experimental and predicted p$LC_{50}$. After preprocessing, population based forward selection were used to select the best subsets of descriptors in the learning methods including 5-fold cross-validation procedure. The support vector machine model was used as the best model ($R^2_{CV}$=0.677, RMSECV=0.887, MSECV=0.674) and also correctly classified 87% for the training set according to EU regulation criteria. The MLR model could describe the structural characteristics of toxic chemicals and interaction with lipid membrane of fish. All the developed models were validated by 5 fold cross-validation and Y-scrambling test.

• The Korean Journal of Pesticide Science
• /
• v.12 no.2
• /
• pp.111-117
• /
• 2008

The comparative molecular field analysis (CoMFA) for the fungicidal activity with N-phenylbenzenesulfonamide analogues (1-45) against gray mold (Botriyts cinerea) were studied quantitatively. The statistical values of CoMFA models had much better predictability and fitness than those of comparative molecular similarity indices analysis (CoMSIA) models. The statistical values of the optimized CoMFA I model were predictablity, $r^2_{cv.}(or\;q^2)=0.457$ and correlation coefficient, $r^2_{ncv.}=0.959$, and their fungicidal activity was dependent on the steric field (52%) and electrostatic field (35.6%) of the substrate molecules. And also, it was found that the optimized CoMFA I model with the sensitivity to perturbation ($d_q^{2'}/dr^2_{yy'}=0.898$) and prediction ($q^2=0.346$ & SDEP=0.614) produced by a progressive scrambling analysis was not dependent on chance correlation. From the results of graphical analyses on the contour maps with the optimized CoMFA I model, it is expected that the $R_3$ and $R_4$-substituents on the N-phenyl ring as steric favor group and para-substituents ($R_1$) on the S-phenyl ring as steric disfavor group will contribute to the fungicidal activity. Therefore, the optimized CoMFA I model should be applicable to the prediction of the fungicidal activities against gray mold.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.8 no.7
• /
• pp.1017-1023
• /
• 2013

Datacommunications transmit the source codes that are coded in information devices, such as computer to the transmission line by means of the line coded signal. AMI method is applied to the line coding method to transmit the signal for long distance. The disadvantage of the AMI method is to loss the bit synchronization when consecutive binary bit '0' over 4ea is coming into line coder. The scrambling technique is used to overcome the problem. The HDB-3 scrambling method is used in Korea standard which standard in ITU-T. When the HDB-3 technology is used. the method should convert the consecutive bit '0' over 4ea to certain bits format. As a result, when there are many such kind of '0' bit stream in source codes, data transmission efficiency will be decreased to treat in line coder, etc. This paper is directed to study the Roman character code system in $KS{\times}1001$, Korea standard for information exchange code in datacommunication systems. Based on the study result, this paper proposed the maximum optimized Roman character code system. In the study, Character coding rule for $4{\times}4$bits and the statistical data for roman character using frequency were considered to simulate. The paper shows the result that when the proposed new roman character coding system is applied to use, the data transmission efficiency could be increased to about 134% compared to existing code system.

• The Korean Journal of Applied Statistics
• /
• v.30 no.1
• /
• pp.41-55
• /
• 2017

This study predicts the average scores of top 150 PGA golf players on 132 PGA Tour tournaments (2013-2015) using data mining techniques and statistical analysis. This study also aims to predict the Top 10 and Top 25 best players in 4 different playoffs. Linear and nonlinear regression methods were used to predict average scores. Stepwise regression, all best subset, LASSO, ridge regression and principal component regression were used for the linear regression method. Tree, bagging, gradient boosting, neural network, random forests and KNN were used for nonlinear regression method. We found that the average score increases as fairway firmness or green height or average maximum wind speed increases. We also found that the average score decreases as the number of one-putts or scrambling variable or longest driving distance increases. All 11 different models have low prediction error when predicting the average scores of PGA Tournaments in 2015 which is not included in the training set. However, the performances of Bagging and Random Forest models are the best among all models and these two models have the highest prediction accuracy when predicting the Top 10 and Top 25 best players in 4 different playoffs.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.13 no.3
• /
• pp.119-126
• /
• 2013

Achieve real-time encryption and video data transcoding, current video encryption methods usually integrate encryption algorithm with video compression course. This paper is devoted to discussing the video encryption technology, by encrypting to avoid unauthorized person getting video data. This paper studied the H.264 entropy coding and proposed of CAVLC video encryption scheme which is combined with the process of entropy coding of H.264 CAVLC encryption scheme. Three encryption levels are proposed. In addition, a scrambling method is also proposed which makes the encrypted frames more robust in anti crack. This method showed more robust video data encryption function and compressive rate.

• Journal of Integrative Natural Science
• /
• v.8 no.1
• /
• pp.40-47
• /
• 2015

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has recently emerged as a promising target in drug discovery. It is involved in multiple cellular processes and associated with the pathogenesis of several diseases. A three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis was performed on a series of GSK-3 inhibitors to understand the structural basis for inhibitory activity. Comparative molecular field analysis (CoMFA) method was used to derive 3D-QSAR models. A reliable CoMFA model was developed using ligand-based alignment scheme. The model produced statistically acceptable results with a cross-validated correlation coefficient ($q^2$) of 0.594 and a non-cross-validated correlation coefficient ($r^2$) of 0.943. Robustness of the model was checked by bootstrapping and progressive scrambling analysis. This study could assist in the design of novel compounds with enhanced GSK-3 inhibitory activity.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.6 no.4
• /
• pp.499-504
• /
• 2011

This paper propose the rule of coding for the characters and symbol, etc which are used in computer, information devices, etc. When they use the rule of coding, they may improve the efficiency of transmission in data communications by reducing the number of scrambling during the line coding in the coder in the transmitter. The paper considered the codes of one byte of 3bits column ${\times}$ 4bits rows. ASCII code is one of the representative code for the codes of one byte of 3bits column ${\times}$ 4bits rows. Therefore, this paper applied ASCII code to study the coding rule of the characters and symbols, etc.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.9 no.4
• /
• pp.469-474
• /
• 2014

Installed on telephone poles laid scrambling to monitor the status of the communication lines, and cost information can provid eadditional information tools to develop systems to support on-site monitoring. Aerial support for a maintenance monitoring module to apply an embedded system, and information processing applications manufactured. In this study, a comprehensive plan in accordance with the government's aerial maintenance work to prevent accidents spread support for the device to immediately take advantage of big cities and aerial maintenance business, Construction worker accused of bias and aims to improve efficiency of maintenance puts.

• Journal of Advanced Navigation Technology
• /
• v.15 no.5
• /
• pp.749-756
• /
• 2011

This paper propose the rule of coding for the characters and symbol, etc which are used in computer, information devices, etc. When they use the rule of coding, they may improve the efficiency of transmission in data communications by reducing the number of scrambling during the line coding in the coder in the transmitter. The paper considered the codes of two bytes(16 bits) of 4bits column ${\times}$ 4bits rows. In the paper, we applied the code system of Roman characters in KS X 1001.

• Journal of Multimedia Information System
• /
• v.2 no.2
• /
• pp.193-206
• /
• 2015

In this paper a new approach for image encryption based on quadruple encryption with dual chaotic maps is proposed. The encryption process is performed with quadruple encryption by invoking the encrypt and decrypt routines with different keys in the sequence EDEE. The decryption process is performed in the reverse direction DDED. The key generation for the quadruple encryption is achieved with a 1D Circle map. The chaotic values for the encrypt and decrypt routines are generated by using a 2D Henon map. The Encrypt routine E is composed of three stages i.e. permutation, pixel value rotation and diffusion. The permutation is achieved by: row and column scrambling with chaotic values, exchanging the lower and the upper principal and secondary diagonal elements based on the chaotic values. The second stage circularly rotates all the pixel values based on the chaotic values. The last stage performs the diffusion in two directions (forward and backward) with two previously diffused pixels and two chaotic values. The security and performance of the proposed scheme are assessed thoroughly by using the key space, statistical, differential, entropy and performance analysis. The proposed scheme is computationally fast with security intact.