• Title/Summary/Keyword: scientific technologies

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Reproductive technologies needed for the generation of precise gene-edited pigs in the pathways from laboratory to farm

  • Ching-Fu Tu;Shu-Hui Peng;Chin-kai Chuang;Chi-Hong Wong;Tien-Shuh Yang
    • Animal Bioscience
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    • v.36 no.2_spc
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    • pp.339-349
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    • 2023
  • Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic cell nuclear transfer, cryopreservation, and nonsurgical embryo transfer. The extension of NBT in the new era of pig breeding depends on the synergistic effect of GE and reproductive biotechnologies; the outcome relies not only on scientific due diligence and operational excellence but also on the feasibility of application on farms to improve sustainability.

A Comparative Analysis of Research Trends in Educational Technology and Learning Sciences through Reviewing of ETR&D and JLS from 2003 to 2012

  • CUI, Fengchao;KIM, Hyeonjin;KIM, Eun-young
    • Educational Technology International
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    • v.15 no.2
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    • pp.171-199
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    • 2014
  • Educational technology (ET) and learning sciences (LS) are two related disciplines that have shared interests in studying technologies for advancing human learning. This study conducted a content analysis of articles published in authoritative academic journals, Educational Technology Research and Development (ETR&D) and Journal of the Learning Sciences (JLS) from 2003 to 2012. By selecting and examining 93 issues with 429 articles during this decade with three analytical frameworks, the purpose of this study is to determine research trends precisely and create a scientific communication and theoretical connections for these two disciplines. The illustrated results indicate the dialogue between these two communities has begun yet accompanied by some certain limitations, whereas, they still need be more cooperative and communicational to move towards further integration, so as to contribute to promoting progressive education, learning theory and practice.

Features of Implementing Pedagogical Practices on the Example of EU Countries' Experience

  • Mykhailo Poplavskyi
    • International Journal of Computer Science & Network Security
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    • v.24 no.2
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    • pp.129-135
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    • 2024
  • Studying at a modern university involves using modern methods and the latest advances in science and education, which applies to Ukraine and all higher education institutions in Europe, determining the relevance of the study and its international significance. The study aims to analyze and implement effective and innovative practices that can be used in integrated educational programs, which include interactive work in education at the European level. The use of general scientific approaches, such as theoretical, statistical, and empirical, allows achieving the set goals. The central hypothesis of the research is the presentation of the best pedagogical practices in the educational program, which includes interactive and universal. The results of the study prove the effectiveness of interactive training. Future research is devoted to developing new pedagogical practices and the development of algorithms for their implementation.

Applications of Bioinspired Platforms for Enhancing Immunomodulatory Function of Mesenchymal Stromal Cells

  • Ok-Hyeon Kim;Tae Jin Jeon;Young In So;Yong Kyoo Shin;Hyun Jung Lee
    • International Journal of Stem Cells
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    • v.16 no.3
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    • pp.251-259
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    • 2023
  • Mesenchymal stromal cells (MSCs) have attracted scientific and medical interest due to their self-renewing properties, pluripotency, and paracrine function. However, one of the main limitations to the clinical application of MSCs is their loss of efficacy after transplantation in vivo. Various bioengineering technologies to provide stem cell niche-like conditions have the potential to overcome this limitation. Here, focusing on the stem cell niche microenvironment, studies to maximize the immunomodulatory potential of MSCs by controlling biomechanical stimuli, including shear stress, hydrostatic pressure, stretch, and biophysical cues, such as extracellular matrix mimetic substrates, are discussed. The application of biomechanical forces or biophysical cues to the stem cell microenvironment will be beneficial for enhancing the immunomodulatory function of MSCs during cultivation and overcoming the current limitations of MSC therapy.

Balancing Water Supply Reliability, Flood Hazard Mitigation and Environmental Resilience in Large River Systems

  • Goodwin, Peter
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.1-1
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    • 2016
  • Many of the world's large ecosystems are severely stressed due to population growth, water quality and quantity problems, vulnerability to flood and drought, and the loss of native species and cultural resources. Consequences of climate change further increase uncertainties about the future. These major societal challenges must be addressed through innovations in governance, policy, and ways of implementing management strategies. Science and engineering play a critical role in helping define possible alternative futures that could be achieved and the possible consequences to economic development, quality of life, and sustainability of ecosystem services. Science has advanced rapidly during the past decade with the emergence of science communities coalescing around 'Grand Challenges' and the maturation of how these communities function has resulted in large interdisciplinary research networks. An example is the River Experiment Center of KICT that engages researchers from throughout Korea and the world. This trend has been complemented by major advances in sensor technologies and data synthesis to accelerate knowledge discovery. These factors combine to allow scientific debate to occur in a more open and transparent manner. The availability of information and improved communication of scientific and engineering issues is raising the level of dialogue at the science-policy interface. However, severe challenges persist since scientific discovery does not occur on the same timeframe as management actions, policy decisions or at the pace sometimes expected by elected officials. Common challenges include the need to make decisions in the face of considerable uncertainty, ensuring research results are actionable and preventing science being used by special interests to delay or obsfucate decisions. These challenges are explored in the context of examples from the United States, including the California Bay-Delta system. California transfers water from the wetter northern part of the state to the drier southern part of the state through the Central Valley Project since 1940 and this was supplemented by the State Water Project in 1973. The scale of these activities is remarkable: approximately two thirds of the population of Californians rely on water from the Delta, these waters also irrigate up to 45% of the fruits & vegetables produced in the US, and about 80% of California's commercial fishery species live in or migrate through the Bay-Delta. This Delta region is a global hotspot for biodiversity that provides habitat for over 700 species, but is also a hotspot for the loss of biodiversity with more than 25 species currently listed by the Endangered Species Act. Understanding the decline of the fragile ecosystem of the Bay-Delta system and the potential consequences to economic growth if water transfers are reduced for the environment, the California State Legislature passed landmark legislation in 2009 (CA Water Code SS 85054) that established "Coequal goals of providing a more reliable water supply for California and protecting, restoring, and enhancing the Delta ecosystem". The legislation also stated that "The coequal goals shall be achieved in a manner that protects and enhances the unique cultural, recreational, natural resource, and agricultural values of the Delta as an evolving place." The challenges of integrating policy, management and scientific research will be described through this and other international examples.

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An Intelligent Decision Support System for Selecting Promising Technologies for R&D based on Time-series Patent Analysis (R&D 기술 선정을 위한 시계열 특허 분석 기반 지능형 의사결정지원시스템)

  • Lee, Choongseok;Lee, Suk Joo;Choi, Byounggu
    • Journal of Intelligence and Information Systems
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    • v.18 no.3
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    • pp.79-96
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    • 2012
  • As the pace of competition dramatically accelerates and the complexity of change grows, a variety of research have been conducted to improve firms' short-term performance and to enhance firms' long-term survival. In particular, researchers and practitioners have paid their attention to identify promising technologies that lead competitive advantage to a firm. Discovery of promising technology depends on how a firm evaluates the value of technologies, thus many evaluating methods have been proposed. Experts' opinion based approaches have been widely accepted to predict the value of technologies. Whereas this approach provides in-depth analysis and ensures validity of analysis results, it is usually cost-and time-ineffective and is limited to qualitative evaluation. Considerable studies attempt to forecast the value of technology by using patent information to overcome the limitation of experts' opinion based approach. Patent based technology evaluation has served as a valuable assessment approach of the technological forecasting because it contains a full and practical description of technology with uniform structure. Furthermore, it provides information that is not divulged in any other sources. Although patent information based approach has contributed to our understanding of prediction of promising technologies, it has some limitations because prediction has been made based on the past patent information, and the interpretations of patent analyses are not consistent. In order to fill this gap, this study proposes a technology forecasting methodology by integrating patent information approach and artificial intelligence method. The methodology consists of three modules : evaluation of technologies promising, implementation of technologies value prediction model, and recommendation of promising technologies. In the first module, technologies promising is evaluated from three different and complementary dimensions; impact, fusion, and diffusion perspectives. The impact of technologies refers to their influence on future technologies development and improvement, and is also clearly associated with their monetary value. The fusion of technologies denotes the extent to which a technology fuses different technologies, and represents the breadth of search underlying the technology. The fusion of technologies can be calculated based on technology or patent, thus this study measures two types of fusion index; fusion index per technology and fusion index per patent. Finally, the diffusion of technologies denotes their degree of applicability across scientific and technological fields. In the same vein, diffusion index per technology and diffusion index per patent are considered respectively. In the second module, technologies value prediction model is implemented using artificial intelligence method. This studies use the values of five indexes (i.e., impact index, fusion index per technology, fusion index per patent, diffusion index per technology and diffusion index per patent) at different time (e.g., t-n, t-n-1, t-n-2, ${\cdots}$) as input variables. The out variables are values of five indexes at time t, which is used for learning. The learning method adopted in this study is backpropagation algorithm. In the third module, this study recommends final promising technologies based on analytic hierarchy process. AHP provides relative importance of each index, leading to final promising index for technology. Applicability of the proposed methodology is tested by using U.S. patents in international patent class G06F (i.e., electronic digital data processing) from 2000 to 2008. The results show that mean absolute error value for prediction produced by the proposed methodology is lower than the value produced by multiple regression analysis in cases of fusion indexes. However, mean absolute error value of the proposed methodology is slightly higher than the value of multiple regression analysis. These unexpected results may be explained, in part, by small number of patents. Since this study only uses patent data in class G06F, number of sample patent data is relatively small, leading to incomplete learning to satisfy complex artificial intelligence structure. In addition, fusion index per technology and impact index are found to be important criteria to predict promising technology. This study attempts to extend the existing knowledge by proposing a new methodology for prediction technology value by integrating patent information analysis and artificial intelligence network. It helps managers who want to technology develop planning and policy maker who want to implement technology policy by providing quantitative prediction methodology. In addition, this study could help other researchers by proving a deeper understanding of the complex technological forecasting field.

Comprehending Polymer-Clay Nanocomposites and Their Future Works (고분자-점토 나노복합체 이해와 향후 연구 방향)

  • Choi, Yeong Suk;Chung, In Jae
    • Korean Chemical Engineering Research
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    • v.46 no.1
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    • pp.23-36
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    • 2008
  • Polymer-clay nanocomposites, a novel organic-inorganic hybrid, attract much attention from both scientific fields and engineering fields due to their balanced improvements in mechanical properties as well as diffusion behaviors, including flame-retarding and barrier properties, with small amounts of clay. Preparation of polymer-clay nanocomposites, summarized as a process for uniform dispersion of hydrophilic layered clays in hydrophobic polymer matrixes, includes several technologies and scientific phenomena, such as surface-modifications of clay layers, physical properties of clays in liquids and dried states, polymer synthesis, polymer rheology, behaviors of polymer solutions/or monomers in the confined geometry, mechanical properties of polymers and clays. To comprehend complicated physical/chemical phenomena involved in the fabrication of nanocomposites, we reviewed physical properties of clays, structures of clays in nanocomposites, characterization of nanocomposites, the relation between morphology and physical property of nanocomposites, surveyed recent research trends, and then suggested a few strategies or methods for fabrication of nanocomposites reflecting future research directions.

Opportunities for Joint Cooperation in R&D for FEALAC Countries: On Nanotechnology and Biotechnology

  • Trujillo, Ivan Montenegro;Jimenez, Edgar E Gonzalez;Ospina, Monica Botero
    • STI Policy Review
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    • v.7 no.2
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    • pp.106-131
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    • 2016
  • The general purpose of this paper is to identify opportunities for and to measure existing collaboration on research and development between institutions from the countries of Asia and Latin America in FEALAC's framework, in the fields of biotechnology and nanotechnology and their convergence. The methodological approach includes scientific and technological surveillance and research seeking to identify both the R&D and innovation capacities of the countries as well as the degree of international cooperation between countries of the two regions; case studies and a study of the governance framework of international collaboration in R&D about issues considered global challenges. The study has three main findings. First, nanotechnology, biotechnology and their convergence contribute to solving the problem of contamination by heavy metals affecting most of the countries that are part of FEALAC and to address problems arising from the accelerated rate of energy consumption, which also contributes to environmental damage. In this scenario, important business opportunities arise from the adaptation and development of bio-refinery technologies. Second, the scientific relationship between FEALAC countries, mainly between Asian and Latin American countries, is weak as can be seen in research for articles and patents. But there is plenty of room and potential for improvement. Third, current and upcoming joint R&D programs and projects should be linked both to existing governance structures and to new ones that serve as experiments of STI public policy regarding innovative management of intellectual property and capacity building. Practical implications are included in lessons learned and a set of recommendations involving a couple of proposals. One proposal calls for research and innovation in promising fields for international cooperation. Another proposal creates mechanisms in the governance framework for sharing knowledge, capacity building, and funding.

User-oriented Information System: Focusing on STEM Field (이용자 중심 정보시스템: STEM 분야 중심으로)

  • Park, Minsoo
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.1
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    • pp.249-253
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    • 2020
  • In order to effectively provide science, technology, engineering, and medicine (STEM) information, an analysis of information users' needs and understanding of information usage behavior must be preceded. Rapid changes and developments in information and communication technologies and the environment have greatly influenced the user's information usage environment. Based on the changes and characteristics of users' information use and their information needs analysis, active design and improvement of scientific and technical information service system is needed. For this study, a total of 816 participants participated: 204 people in four main contents (papers, reports, trends, and patents) through significant allocation extraction for STEM information users. A survey was conducted to grasp the status of the use of science and technology information using quantitative methods through online surveys for users of each content (papers, reports, trends, patents). Based on the analysis results, the implications for the improvement of STEM field information system were drawn.

Prospects for Future Multi-disciplinary Collaboration

  • Lai, Claudia K.Y.
    • Perspectives in Nursing Science
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    • v.4 no.1
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    • pp.9-18
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    • 2007
  • Background: Intersectoral and multidisciplinary collaboration is becoming more prominent in all facets of government, health, social services, and scientific endeavors. An interplay of a multitude of driving forces moves multiple disciplines forward to achieve quality outcomes in health and social sciences services and research. Aim: This paper aims at discussing the prospects for future multidisciplinary collaboration. If inter organizational integration and multidisciplinary collaboration are the ways of the future in academia and the scientific world, it then becomes crucial to examine what lies ahead for the nursing profession, Discussion: This paper argues that in order for multidisciplinary endeavors to succeed, the leaders in multidisciplinary teams shoulder the largest share of the responsibilities involved. In developing a lasting team constituting professionals from different disciplines, the leader needs to include the right individuals in the team, identify a common goal, build trusting relationships through open communication and interprofessional education, and empower members through creating room for autonomy and at the same time allowing space for personal development. The leader will need to utilize information technologies to manage communication issues in a large multi-site multidisciplinary project. Lastly, he or she must be able to demonstrate team productivity through process and outcome evaluation. It needs to be emphasized that it falls to each individual nurse to speak up and act upon what nursing believes and represents in our quest for success in multidisciplinary endeavors. Conclusion: The significance of the role of the leader is paramount for a team to succeed. Yet there is no prospect if only a handful of exceptional nurse leaders are moving ahead in multidisciplinary endeavors. Without the actualization of professional roles by each individual nurse, the profession will have no prospect in collaborations across disciplines.

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