• Korean journal of food and cookery science
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• v.28 no.1
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• pp.9-15
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• 2012

This study analyzed the antibacterial activity of a Rubus coreanum (Bokbunja) ethanol extract. The antimicrobial activity was determined by disc diffusion, minimum inhibitory concentration (MIC), and growth inhibition methods with seven kinds of bacteria related to foodborne illness (Bacillus cereus, Escherichia coli, Escherichia coli O157:H7, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, and Salmonella typhimurium). In the results, disc diffusions of the ethanol extract from R. coreanum (9.8-17.5 mm at $4,000{\mu}g/disc$) clearly showed the antimicrobial activity of the extract against all tested microorganisms. Rubus coreanum promoted an inhibitory effect as follows: E. coli O157:H7 > P. aeruginosa > L. monocytogenes > E. coli > S. aureus > B. cereus ${\geq}$ S. typhimurium. In the MIC test, R. coreanum showed high antimicrobial effect against L. monocytogenes at 500 ppm. Moreover, the R. coreanum ethanol extract showed strong growth inhibition against microorganisms, similar to the MIC results. These results show that a R. coreanum ethanol extract has powerful antimicrobial activity against all tested microorganisms, suggesting that R. coreanum will be useful as a potential natural preservative.

• Journal of Korean Elementary Science Education
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• v.33 no.1
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• pp.1-20
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• 2014

This study aimed to find out the current conditions and the characteristics of elementary students' science-related engagement in informal education setting. For this, we conducted a survey targeting 645 $6^{th}$ grader elementary students of three elementary school in Seoul. The results were described as following aspects: first, the place, the engagement frequency, and companies of students' science-related activity in informal setting, second, the characteristics of engagement based on homogeneity analysis. Based on these results, we suggested several ways to encourage students' science-related engagement in informal education setting.

• Journal of Korean Biological Nursing Science
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• v.17 no.4
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• pp.287-296
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• 2015

Purpose: The purpose of this study was to identify the influence of physical activity and depression on sleep quality among the young-old and old-old community-dwelling elderly. Methods: Participants were 216 community-dwelling older adults in Korea aged 65 or above. Data were collected using structured questionnaires with face-to-face interviews that included demographic and health-related characteristics, International Physical Activity Questionnaires (IPAQ), the Short Form Geriatric Depression Scale (SGDS) and the Pittsburgh Sleep Quality Index (PSQI). A hierarchical multiple regression was conducted to examine whether physical activity and depression would predict sleep quality under other controlled factors. Results: There were differences in demographic and health-related characteristics, physical activity, and depression by age groups, but not in sleep quality. In the young-old elderly, physical activity (${\beta}=-0.22$, p=.043) and depression (${\beta}=0.31$, p=.002) were significantly associated with sleep quality (F=4.46, p=.001, Adjusted $R^2=.16$). In the old-old elderly, physical activity (${\beta}=-0.29$, p=.001) and depression (${\beta}=0.41$, p<.001) were significantly associated with sleep quality (F=10.79, p<.001, Adjusted $R^2=.29$). Conclusion: These finding highlight physical activity and depression as important contributors to sleep quality in both young-old and old-old elderly.

• Journal of The Korean Association For Science Education
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• v.17 no.2
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• pp.163-178
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• 1997

The purpose of this study is to investigate the effect of categorizing activities in lessons on improving critical thinking to meet energy environment issues in every day situation, supposing that there are not only scientific concepts but also critical thinking ability in scientific literacy to meet social controversies related with science intelligently. Categorizing Activity Program was developed and applied to the 10th grades(n=51) in Seoul for about one month. The program was consisted of two domains. They studied science concepts of various aspects of science, technology and society related with energy and environment in the first and second domain repectively, in the while, two critical tasks which include articles from newspapers and magazines were assigned to them for the development and evaluation of critical thinking abilities. The scores of critical thinking ability, the cognitive element, and critical thinking inclination, the affective element, were increased meaningfully(p<.05). In conclusion, categorizing activity as a strategy of concept attainment was effective in improving critical thinking for seeing various aspects with various view points needed in controversial issues related with energy and environment.

• Journal of Apiculture
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• v.32 no.4
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• pp.327-332
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• 2017

In this study, we studied the changes in antioxidant activity of Actinidia arguta fruit of Autumn Sense cultivar during fruit ripening. The aim of this investigation was to find the knowledge of the changes of physiochemicals associated with fruit quality, antioxidant properties (free-radical scavenging activity and reducing power), total phenolics and vitamin C during fruit ripening. The highest free-radical scavenging activity (at $100{\mu}g/ml$) and reducing power (at $100{\mu}g/ml$) in A. arguta fruit were 78.57% and 0.22, respectively. Total phenolic content and vitamin C content in fruit of 10 days after fruit set were $639.48{\mu}g/g$ and $1052.2{\mu}g/g$, respectively. In general, the antioxidant activity and the related parameters, including total phenolic content and vitamin C content decreased during fruit ripening. These results improve knowledge of the effect of ripening on the antioxidant activity and related compounds contents that could help to establish the optimum A. arguta fruit harvest data for various usages.

• Analytical Science and Technology
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• v.36 no.1
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• pp.44-52
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• 2023

This protocol clarifies a simple and precise method for measuring the activity of xanthine oxidase (XO) enzyme inhibitor. XO enzyme, which accelerates oxidative stress-related disorders through its capacity to generate hydrogen peroxide and superoxide anion radicals (O₂^•-), has been found to be inhibited by several plant extracts. Enzyme samples were incubated with a suitable buffer containing adequate amounts of xanthine as a substrate to determine XO activity. The method depends on direct measurements of uric acid and hydrogen peroxide production to test XO with and without interference. The CUPRAC reagent (Cu(Nc)₂²⁺) was used to inhibit enzyme reaction after incubation was complete. The generated urate and peroxide reduced the Cu(II)-neocuproine complex (Cu(Nc)₂²⁺) to a brightly colored Cu(I)-neocuproine complex (Cu(Nc)₂⁺), which was assessed with a spectrophotometer at 450 nm. XO activity was found to be directly related to the increased absorbance of the colored Cu(I)-neocuproine complex (Cu(Nc)₂⁺). To eliminate catalase enzyme interference, the proposed method used sodium azide and was validated against XO activity using the UV method in matched samples with t-test analysis. The proposed assay can determine XO activity with high precision, as indicated by the correlation coefficient (R² = 0.9935) from comparison with the reference protocol.

• Journal of Information Science Theory and Practice
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• v.8 no.3
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• pp.47-63
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• 2020

This study focuses on users of activity tracking technologies and their related information behavior. How useful is the provided information by the trackers? Do users understand all information and explanations? We conducted a web-based survey. All in all, 631 users of a tracking device filled out the survey. From the perspective of information science, this investigation aims to analyze information needs considering different types of the provided information by activity tracking technologies. Are users satisfied by using the information on their steps, heart rates, and sleep duration? How do users assess readability about heart rate zones and sleep stages? Additionally, we investigated if users understand how to reflect on and adapt their health behavior based on the received explanations. According to the results, users mainly agree that the received information (raw data as well as - to a lesser extent - aggregated data in the form of corresponding diagrams) is useful, that the explanations are easy to understand, and that they know how to use this obtained information. This investigation enables an in-depth insight into how users are applying the self-quantifying activity and health information and which information needs are satisfied.

• Journal of Agricultural Extension & Community Development
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• v.30 no.4
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• pp.187-197
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• 2023

The study aims to identify factors related to landscape structure and socioeconomic characteristics that influence adults' physical activity and health. The study analyzes data from 148,643 respondents from the Korea Community Health Survey conducted in 2021. The study measures various factors, including the frequency of physical activity, stress, depression, and landscape metrics of forest patches. Hierarchical multiple regression analysis was used, controlling for socio-demographic characteristics. Larger forest patches and more irregular shapes are associated with higher levels of physical activity among adults. The percentage and area of the forest patch are associated with fewer mental health complaints. Configuration-related landscape metrics such as shape or arrangement of the forest patch did not show a significant association with physical activity. Overall, the study provides insights into how specific characteristics of forest patches in urban areas may influence physical activity and mental health among adults. It emphasizes the importance of green spaces and their potential positive effects on both physical and mental well-being.

• Biomolecules & Therapeutics
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• v.29 no.3
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• pp.331-341
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• 2021

Liver cancer is a common tumor and currently the second leading cause of cancer-related mortality globally. Liver cancer is highly related to inflammation as more than 90% of liver cancer arises in the context of hepatic inflammation, such as hepatitis B virus and hepatitis C virus infection. Despite significant improvements in the therapeutic modalities for liver cancer, patient prognosis is not satisfactory due to the limited efficacy of current drug therapies in anti-metastatic activity. Therefore, developing new effective anti-cancer agents with anti-metastatic activity is important for the treatment of liver cancer. In this study, SP-8356, a verbenone derivative with anti-inflammatory activity, was investigated for its effect on the growth and migration of liver cancer cells. Our findings demonstrated that SP-8356 inhibits the proliferation of liver cancer cells by inducing apoptosis and suppressing the mobility and invasion ability of liver cancer cells. Functional studies revealed that SP-8356 inhibits the mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways, which are related to cell proliferation and metastasis, resulting in the downregulation of metastasis-related genes. Moreover, using an orthotopic liver cancer model, tumor growth was significantly decreased following treatment with SP-8356. Thus, this study suggests that SP-8356 may be a potential agent for the treatment of liver cancer with multimodal regulation.

• Journal of Korean Elementary Science Education
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• v.23 no.3
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• pp.208-218
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• 2004

Many elementary school students have misconception related to dissolution and solution. Moreover, they usually fail to apply the results of the experiments in their science classes to their everyday life, and also have low science achievement. Therefore, they are not interested in science, and sometimes some of them are even afraid of it. The purposes of this study is to investigate the effects of concept mapping activity on science achievement and attitude. In addition, this study also aims at presenting the teaching and learning method of utilizing concept maps in order to have the students form correct concepts. The subjects were classified into two groups one group is composed of thirty-seven students (experimental group) who were participated in concept mapping activity, and the other is composed of thirty-eight students (comparison group) who were participated in the traditional teaching method. The major findings of this study are as follows: First, the concept mapping activity has a positive effect on improving students＇ science achievement. Second, the classes using concept maps have a good influence on forming students＇ science attitude. Third, the concept mapping activity is more effective in improving science achievement of mid and low level students. In conclusion, the loaming by concept mapping activity positively influence students＇ science achievement and attitude. Particularly for the students in mid and high levels, the effect is more remarkable.