• Journal of the Korea Convergence Society
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• v.12 no.5
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• pp.327-335
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• 2021

The aim of this study is to examine the effectiveness of group art therapy on the depression and job satisfaction of local government officials. The study was conducted from March 2017 to March 2018 and the participants of this study were twenty public officials in North Chung-Chung Province. They randomly placed in two different group : 10 in experimental group, 10 in control group. To measure the effects of group art therapy, K-BDI and Job Satisfaction Scale were used a week before and a week after the intervention of group art therapy program. Data was analyzed using paired t-test with SPSS Statistics 23.0. The result was as follows : First, there was significant change to alleviate Depression. Second, there was significant change to increase job satisfaction. This study provides empirical evidence of effectiveness of group art therapy. The findings in this study are not only helping public officials' individual mental health but also enhancing productivity of local government and the quality of service to local residents in Chung-Chung province area.

• Journal of the Korea Convergence Society
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• v.10 no.1
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• pp.155-161
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• 2019

As composite is the light weight material whose durability and mechanical property are more superior than the existing general material. By taking notice of the composite with light weight, this study was about to investigate the static fracture characteristic of the bonded CFRP structure jointed with adhesive. Also, CFRP double cantilever beam with the variable of laminate angle was designed and the static fracture analysis was carried out. The laminate angles of CFRP double cantilever beam designed for this study were $30^{\circ}$, $45^{\circ}$ and $60^{\circ}$ individually. As the study result, the specimen with the laminate angle of $45^{\circ}$ was shown to have the durability better than those with the layer angles of $30^{\circ}$ and $45^{\circ}$. It was checked that the specimen with the laminate angle of $30^{\circ}$ had the weakest durability among all specimens. The damage data of the bonded CFRP structure by laminate angle could be secured through this study result. As the damage data of bonded interface obtained on the basis of this study result are utilized, the esthetic sense can be shown by being grafted onto the machine or structure at real life.

• Journal of the Korea Convergence Society
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• v.10 no.2
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• pp.57-66
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• 2019

The purpose of this study was to identify the risk factors of breast disease by checking the difference in lifestyle and the natural estrogen-containing food intake. The subjects were women who visited the J-City Women's Hospital between the ages of 20 and 60 (disease=85, non disease=93) and to avoid the demographic factors that might affect lifestyle, and to ensure the homogeneity of the two groups, (${\pm}5$ years old) were randomly expressed. The logistic regression analysis was performed to examine the influence of variables on breast disease. The probability of receiving a diagnosis of breast disease increased by 3.04 times, the probability of receiving a diagnosis of breast disease was 4.76 times higher than that of others such as brown rice grains, and the hobby life of stress relieving methods The probability of being classified as breast disease was 2.38 times. People who have experience of artificial abortion, those who enjoy white rice, and those who do not enjoy hobbies are more likely to be diagnosed with breast disease. The breast disease prevention and education program and the education program for the general public reflecting this characteristic will be necessary.

• Journal of the Korea Convergence Society
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• v.9 no.12
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• pp.175-180
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• 2018

In this study, CFRP was manufactured with the laminate angle of $45^{\circ}$. The specimen of TDCB bonded with the adhesive for structure was designed by CATIA and the analysis was progressed by using the finite element analysis program of ANSYS. This study model was designed on the basis of British industry and ISO standard and the configuration factor(m) was established with variable according to the angle of model configuration. As the study result of this paper, the maximum deformations at the specimens with the tapered angles of $4^{\circ}$ and $8^{\circ}$ become most as 12.628 mm and least as 12.352mm respectively. Also, the maximum equivalent stresses at the specimens with the tapered angles of $6^{\circ}$ and $8^{\circ}$ become most as 9210.3 MPa and least as 4800.5 MPa respectively. The damage data of TDCB structure with the laminate angle which was manufactured with CFRP could be secured through this study result. As the damage data of TDCB structure bonded with CFRP obtained on the basis of this study result are utilized, the esthetic sense can be shown by being grafted onto the machine or structure at real life.

• Journal of the Korean Wood Science and Technology
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• v.47 no.4
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• pp.519-532
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• 2019

The objectives of this study were to evaluate the effects of shelling ratio and resin content on the properties of bamboo oriented strand board (BOSB) from betung (Dendrocalamus asper) and to determine the correlation between the results of dynamic and static bending tests. Strands were steam-treated at $126^{\circ}C$ for 1 h under 0.14 MPa pressure and followed by washing with 1% NaOH solution. Three-layer BOSB with the core layer perpendicular to the surface was formed with shelling ratios (face:core ratio) of 30:70; 40:60; 50:50; 60:40 and binded with 7% and 8% of phenol formaldehyde (PF) resin with the addition of 1% of wax. The evaluation of physical and mechanical properties of BOSB was conducted in accordance with the JIS A 5908:2003 standard and the results were compared with CSA 0437.0 standard for commercial OSB (Grade O-1). Non-destructive testing was conducted using Metriguard Model 239A Stress Wave Timer which has a wave propagation time from 1 to $9,999{\mu}s$ and a resolution of $1{\mu}s$. BOSB with 8% resin content showed better physical and mechanical properties than those with 7% resin content. The increase of the face layer ratio improved the strength of BOSB in parallel direction to the grain. The results suggested that shelling ratio of 50:50 could be used as a simple way to reduce PF resin requirements from 8% to 7% and to meet the requirements of CSA 0437.0 standard. The results of non-destructive and destructive tests showed a strong correlation, suggesting that non-destructive test can be used to estimate the bending properties of BOSB.

• Journal of the Korean Orthopaedic Association
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• v.53 no.6
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• pp.478-489
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• 2018

Total knee arthroplasty has become a standard procedure for advanced knee arthritis to relieve pain and improve function. Computer-assisted navigation systems have been used in total knee arthroplasty to improve the mechanical axis of the limb as well as the alignment and position of the components. A computer-assisted navigation system has the advantage of real-time feedback during surgery, such as mediolateral balance in extension and flexion gap, alignment of the lower limb, and components. On the other hand, the computer-assisted navigation system requires an additional stab wound for tracker fixation, which can increase the likelihood of superficial wound infection and stress fractures and increase the operation time and cost of surgery. The clinical efficacy of computer-assisted navigation in total knee arthroplasty is also controversial. Compared to the conventional technique, computer navigation improves the accuracy of the postoperative mechanical axis within outliers of $3^{\circ}$ varus or $3^{\circ}$ valgus. This paper reviews the surgical technique, pitfalls, clinical and radiological outcomes, useful clinical cases, and future perspectives in computer-assisted navigation total knee arthroplasty.

• Journal of Pharmacopuncture
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• v.22 no.1
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• pp.28-34
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• 2019

Background: Breast cancer is a complex, heterogeneous disease and one of the most common malignancies in women worldwide. The efficacy of chemotherapy as an important breast cancer treatment option has been severely limited because of the inherent or acquired resistance of cancer cells. The molecular chaperone heat shock protein 90 (HSP90) upregulated in response to cellular stress is required for functions such as conformational maturation, activation and stability in more than 200 client proteins, mostly of the signaling type. In this study, the expression of HSP90 isoforms including $HSP90{\alpha}$ and $HSP90{\beta}$ in breast cancer cell lines before and after treatment with doxorubicin (DOX) was assessed. Material and Methods: The cell cytotoxicity of DOX in MDA-MB-231 and MCF-7 cell lines was determined using the MTT assay. immunofluorescence and western blotting techniques were used to determine the expression of $HSP90{\beta}$ in the cell lines before and after DOX treatment. Immunofluorescence was also conducted to ascertain the expression of $HSP90{\alpha}$. Results: The MTT assay results showed that the MDA-MB-231 cells ($IC_{50}=14.521{\mu}M$) were more sensitive than the MCF-7 cells ($IC_{50}=16.3315{\mu}M$) to DOX. The immunofluorescence results indicated that the expression of $HSP90{\alpha}$ in both cell lines decreased after exposure to DOX. The western blot and immunofluorescence analyses showed that $HSP90{\beta}$ expression decreased in the MCF-7 cells but increased in the MDA-MB-231 cells after DOX treatment. Conclusion: The obtained results suggested that $HSP90{\alpha}$ and $HSP90{\beta}$ expression levels were reduced in the MCF-7 cells after exposure to DOX. In the MDA-MB-231 cells, $HSP90{\alpha}$ expression was reduced while $HSP90{\beta}$ was found to be overexpressed following DOX treatment.

• Journal of Convergence for Information Technology
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• v.9 no.7
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• pp.85-93
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• 2019

The purpose of this study is to identify the influence of demographic characteristics such as inappropriate lifestyle, stress, and health status among health risk factors of early adolescents according to gender. There is a gender difference in the perception of mental and physical health of early adolescents, and the result can be different in behavior patterns between men and women. This study was conducted to identify the health risk factors as independent variables for early adolescents in Daegu and Gyeongbuk area, and to analyze the determinants of gender (male, female) differences by parents, family environment, friends, academic background, appearance, grade, location, school grades, family situation, and health status as demographic factors. And, the Odds Ratio of the early adolescents was analyzed through logit analysis and the differences according to the influence relationship of each of them were examined. As a result of the analysis, the more the sleep and physical activity, parents, home environment, friends, academic background, and appearance are increased, the more the influence is likely to become on the male students. On the contrary, the rest of the health risk factors can increase, and the threat to the health risk factors is likely to become severe to the female students.Among them, it is necessary to develop a pre-preventive program for early adolescents' health risk factors, provide basic data for practical application in the field, and seek a detailed program according to the gender of early adolescents.

• Journal of Korea Society of Industrial Information Systems
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• v.24 no.4
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• pp.99-112
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• 2019

The landscape of the education market is changing. As part of efforts to deal with the decrease of a school-age population in Korea, Korean universities and colleges are endeavoring to attract foreign students. Chinese students, the largest share of foreign university students in Korea, are becoming an important element at Korean universities and colleges. Chinese students face various kinds of difficulties while trying to cope with new environments in the country. This study aims to analyze the impact of academic factors and psychological factors of Chinese students on the level of adaptation to university life and their satisfaction with it. Data on 128 Chinese students attending D University located in Busan were collected and a path analysis was conducted using partial least squares (PLS) regression. Research results are as follows. First, professors as an academic factor and the level of interest of university staff have significant impact on the level of adaptation to university life while Korean language proficiency does not have significant impact on the level of adaptation to university life. Second, homesickness as a psychological factor is correlated to the level of adaptation to university life with significance while acculturative stress is not correlated to it. Third, the level of adaptation to university life is correlated to the level of satisfaction with university life. Based on these findings, the significance, limitations and future directions of this study are discussed.

• Biomolecules & Therapeutics
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• v.29 no.6
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• pp.685-696
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• 2021

In this study, we investigated the inhibitory effect of 5-aminolevulinic acid (ALA), a heme precursor, on inflammatory and oxidative stress activated by lipopolysaccharide (LPS) in RAW 264.7 macrophages by estimating nitric oxide (NO), prostaglandin E2 (PGE2), cytokines, and reactive oxygen species (ROS). We also evaluated the molecular mechanisms through analysis of the expression of their regulatory genes, and further evaluated the anti-inflammatory and antioxidant efficacy of ALA against LPS in the zebrafish model. Our results indicated that ALA treatment significantly attenuated the LPS-induced release of pro-inflammatory mediators including NO and PGE2, which was associated with decreased inducible NO synthase and cyclooxygenase-2 expression. ALA also inhibited the LPS-induced expression of pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6, reducing their extracellular secretion. Additionally, ALA abolished ROS generation, improved the mitochondrial mass, and enhanced the expression of heme oxygenase-1 (HO-1) and the activation of nuclear translocation of nuclear factor-E2-related factor 2 (Nrf2) in LPS-stimulated RAW 264.7 macrophages. However, zinc protoporphyrin, a specific inhibitor of HO-1, reversed the ALA-mediated inhibition of pro-inflammatory cytokines production and activation of mitochondrial function in LPS-treated RAW 264.7 macrophages. Furthermore, ALA significantly abolished the expression of LPS-induced pro-inflammatory mediators and cytokines, and showed strong protective effects against NO and ROS production in zebrafish larvae. In conclusion, our findings suggest that ALA exerts LPS-induced anti-inflammatory and antioxidant effects by upregulating the Nrf2/HO-1 signaling pathway, and that ALA can be a potential functional agent to prevent inflammatory and oxidative damage.