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A Review of Research Trends on Trauma in Maritime Police Officers and Police Officers in Korea (해양경찰·경찰 공무원의 외상(trauma)관련 국내 연구 동향)

  • Park, Kyung Ryun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.4
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    • pp.327-335
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    • 2020
  • The purpose of this study was to analyze research trends on trauma in maritime police officers and police officers in Korea and suggest future research directions. We collected 57 studies related to trauma in maritime police and police from Korean Citation Index listed journals and analyzed basic information, subjects, research methods, measurements and related variables. The results showed that studies have been conducted sporadically from 2010 and only six out of the 57 studies were conducted for maritime police officers. Police administration (59.6 %) was the most common area of researchers' major, followed by psychology (19.3 %), medicine and nursing (10.5 %), social welfare (8.8 %) and education(1.8 %). Five out of the six maritime police studies were conducted in the police administration field. Most of the studies adopted the quantitative research method (78.9 %). Only three studies adopted the qualitative method, all of which targeted police officers. The IES-R-K was the most used PTSD scale, followed by the PDS and the PCL-5. Trauma-related variables were commonly conducted in the order of traumatic event experience, resilience, stress-coping methods and social support. Finally, the implications of the findings of our study and the suggestions for further research were discussed.

Role of the MDM2 Promoter Polymorphism (-309T>G) in Acute Myeloid Leukemia Development

  • Cingeetham, Anuradha;Vuree, Sugunakar;Jiwatani, Sangeeta;Kagita, Sailaja;Dunna, Nageswara Rao;Meka, Phanni Bhushann;Gorre, Manjula;Annamaneni, Sandhya;Digumarti, Raghunadharao;Sinha, Sudha;Satti, Vishnupriya
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2707-2712
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    • 2015
  • Background: The human homologue of the mouse double minute 2 (MDM2) gene is a negative regulator of Tp53. MDM2-309T>G a functional promoter polymorphism was found to be associated with overexpression thereby attenuation of Tp53 stress response and increased cancer susceptibility. We have planned to evaluate the possible role of MDM2-309T>G polymorphism with risk and response to chemotherapy in AML. Materials and Methods: A total of 223 de novo AML cases and 304 age and sex matched healthy controls were genotyped for the MDM2-309T>G polymorphism through the tetra-primer amplification refractory mutation system (ARMS)-PCR method. In order to assess the functional relationship of -309T>G SNP with MDM2 expression level, we quantified MDM2 mRNA in 30 primary AML blood samples through quantitative RT-PCR. Both the (-309T>G) genotypes and the MDM2 expression were correlated with disease free survival (DFS) rates among patients who have achieved complete remission (CR) after first induction chemotherapy. Results: MDM2-309T>G polymorphism was significantly associated with AML development (p<0.0001). The presence of either GG genotype or G allele at MDM2-309 confered 1.79 (95% CI: 1.12-2.86; p<0.001) and 1.46 fold (95%CI: 1.14-1.86; p= 0.003) increased AML risk. Survival analysis revealed that CR+ve cases with GG genotype had significantly increased DFS rates (16months, p=0.05) compared to CR+ve TT (11 months) and TG (9 months) genotype groups. Further, MDM2 expression was also found to be significantly elevated in GG genotype patients (p=0.0039) and among CR+ve cases (p=0.0036). Conclusions: The MDM2-309T>G polymorphism might be involved in AML development and also serve as a good prognostic indicator.

Burdens, Needs and Satisfaction of Terminal Cancer Patients and their Caregivers

  • Chang, Yoon-Jung;Kwon, Yong Chol;Lee, Woo Jin;Do, Young Rok;Lee, Keun Seok;Kim, Heung Tae;Park, Sook Ryun;Hong, Young Seon;Chung, Ik-Joo;Yun, Young Ho
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.209-215
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    • 2013
  • Objectives: Terminal cancer patients and their caregivers often experience traumatic stress and need many types of assistance. In the present study we interviewed terminally ill cancer patients and caregivers to determine how much burden they experienced and to find out what factors are most important for satisfaction. Design: We constructed a questionnaire including overall care burden and needs experienced, and administered it to 659 terminal cancer patients and 659 important caregivers at 11 university hospitals and 1 national cancer center in Korea. Results: Finally, 481 terminal cancer patients and 381 caregivers completed the questionnaire. Care burden was not insubstantial in both and the caregiver group felt more burden than the patient group (P<0.001). While the patient group needed financial support most (39.0%), the caregiver group placed greatest emphasis on discussion about further treatment plans (44.8%). Stepwise multiple logistic regression analyses showed that in the patient group, patient's health status (OR, 2.03; 95%CI, 1.16-3.56) and burden (OR, 2.82; 95%CI, 1.76-4.50) influenced satisfaction about overall care, while in the caregiver group, high education level (OR, 1.84; 95%CI, 1.76-4.50), burden (OR, 2.94; 95%CI, 1.75-4.93) and good family function (OR, 1.94; 95%CI, 1.24-3.04) were important. Conclusions: Our study showed that burden was great in both terminal cancer patients and their caregivers and was perceived to be more severe by caregivers. Our study also showed that burden was the factor most predicting satisfaction about overall care in both groups.

Self-care Status of the Aged Diabetic Patients with Noncompliance (일개 종합병원에서의 치료 미순응 노인 당뇨병 환자의 자가관리 실태)

  • Kim, So-Mi;Hwang, Tae-Yoon;Nah, Min-Ah;Lee, Kyeong-Soo;Yeom, Seog-Heon
    • Journal of agricultural medicine and community health
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    • v.42 no.4
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    • pp.226-233
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    • 2017
  • Objective: The purpose of this study was to describe and understand self-care status of the aged diabetic patients with noncompliance after hospital discharge. Methods: A qualitative research method was used for the study design. The participants were 15 diabetic patients aged 65 or older who had been admitted more than two times for hyperglycemia in the past 1 year in a general hospital in Daegu. Data were collected from November 1 2015 to March 1 2016 through in-depth personal interview. Results: Patients' knowledge level on causes and symptoms of diabetes was low. Most participants rarely and irregularly checked blood sugar at home. They were under a lot of stress from their family. Due to old age and illness they did not have sufficient physical activity and they have had rarely regular meals. They considered the self-care education program unnecessary and there was limitations of accessibility for education. Conclusions: The aged diabetic patients who had the repeat admission did not perform self-care activities properly and had problems especially in blood glucose check, support from their family, and health education after returning home. More personalized and community-based self-management education programs will be necessary.

A Study on Health Perception and Health Promoting Behavior in the Elderly (노인의 건강지각과 건강증진행위)

  • Lee, Kyeong-Sook;Chung, Young-Sook
    • Research in Community and Public Health Nursing
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    • v.9 no.1
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    • pp.72-88
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    • 1998
  • This study was designed to identify the relationship between health perception arid health promoting behavior in the elderly. The subjects for this study were 92 persons over 65, who could be easily met in households, pavilions for the aged, and parks. The data were collected during the period from March 24th to April 12th, 1997 by interviews with a structured questionnaire. The instruments used for this study are as follows: The Health Perception Questionnaire developed by Ware (1979) and translated by Yu Ji-Su(1985). The Health Promotion Lifestyle Profile(HPLP) developed by Walker, Sechrist & Pender (1987) and partially amended by the author of this study. The Health Promotion Lifestyle Profile(HPLP) was parameterized by nutrition, exercise, stress management, self actualization, health responsibility, and interpersonal support. The data was analyzed by frequency, percentage, mean, standard deviation, t - test, ANOVA, and Pearson's correlation using an SPSS program. The results of this study were as follows: 1. Hypothesis 1 : 'The higher the level of health perception in the elderly, the higher the practice of health promoting behavior in the elderly' was supported(r=0.449, p<0.001). 2. The health perception mean score on a four point scale was 2.564. 3. For health promoting behavior, the mean score on a four point scale was 2.560. The factor of the highest mean score was interpersonal support(2.850) and factor of the lowest mean score was exercise(1.964). 4. Among the general characteristic variables, sex(t=4.12, p<0.001), religion(t=2.47, p<0.05), education(F=3.27, p<0.05), marital status (t=2.22, p<0.05), living situation(F=3.50, p<0.05), and hobby(t= -2.57, p<0.05) showed strong connections to health perception. 5. Among the general characteristic variables, religion(t = 1.83, p<0.05), and marital status(t= 2.12, p<0.05) showed strong connections to health promoting behavior. In conclusion, this study revealed that health perception is an important factor related to health promoting behavior in the elderly. The general characteristic variables showed strong connections to health perception and health promoting behavior. Therefore, nurses should consider health perception and general characteristic variables when they plan nursing intervention for the elderly. Also, educational programs encouraging constructive health perception should be developed.

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New Approach for Shear Capacity Prediction of High Strength Concrete Beams without Stirrups (스터럽이 없는 고강도 콘크리트 보의 전단강도 예측을 위한 새로운 예측식의 제안)

  • Choi, Jeong-Seon;Lee, Chang-Hoon;Yoon, Young-Soo
    • Journal of the Korea Concrete Institute
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    • v.18 no.5 s.95
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    • pp.611-620
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    • 2006
  • In the shear failure mechanism of a beam, beam and arch actions always exist simultaneously. According to the shear span to depth ratio, the proportion between these two actions is varied and the contribution of these actions to shear capacity is changed. Moreover, the current codes provide recommendations based on experimental results of normal strength concrete, so the application range of concrete strength must be extended. Based on this mechanism and new requirement, a simplified analytical equation for shear capacity prediction of reinforced high strength concrete beams without stirrups is proposed. To reflect the change in the contribution between these actions, stress variation in the longitudinal reinforcement along the span is considered by use of the Jenq and Shah Model. Dowel action with horizontal splitting failure and shear friction between cracks are also taken into account. ize effect is included to derive a more precise equation. Regression analysis is performed to determine each variable and simplify the equation. And, the formula derived from theoretical approaches is evaluated by comparison with numerous experimental data, which are in broad range of concrete strength(especially in high strength concrete), shear span to depth ratio, geometrical size and longitudinal steel ratio. It is shown that the proposed equation is more accurate and simpler than other empirical equations, so a wide range of a/d can be considered in one equation.

Outdoor Sports and e-sports Participation based Measuring Model Design for the Mental and Social Health of Adolescents (아웃도어 스포츠와 e-스포츠 기반의 청소년 정신적 사회적 건강 측정 모델 설계)

  • Kim, SeongKwan
    • Journal of the Korea Convergence Society
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    • v.7 no.5
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    • pp.269-277
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    • 2016
  • This study was aimed to study the effects of adolescents' outdoor sports and e-sports activities on their holistic health. In order for this, adolescent holistic health has been divided into three categories: physical health, mental health, and social health; and reviewed existing research on outdoor sports and e-sports. The research has found several variables for measuring the correlation between the two types of sports. The variables cover four areas: 1) General Information, determined by gender, age, preferred sport, and length of play; 2) Physical Health, as measured by six questions in the basic PAPS (Physical Activity Promotion System) survey; 3) Mental Health, as measured by stress index, self-efficacy, subjective health, and self-esteem; and 4) Social Health, as measured by variables relating to family, friends, school, and society. A total of 36 questions were devised, with 1-4 questions in each area. Primarily it examined the mental health social health. As a result, it was found that three factors have a difference such that the significance of self satisfaction. family relationships, friendships is 0.064, 0.012, 0.088 respectably.

Mechanism Underlying the Anti-Inflammatory Action of Piceatannol Induced by Lipopolysaccharide (당지질로 유도한 염증반응에서 Piceatannol의 항염증 기전 연구)

  • Cho, Han-Jin;Shim, Jae-Hoon;So, Hong-Seob;YoonPark, Jung-Han
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.9
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    • pp.1226-1234
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    • 2012
  • 3,4,3',5'-Tetrahydroxy-trans-stilbene (piceatannol) is a derivative of resveratrol with a variety of biological activities, including anti-inflammatory, anti-proliferative, and anti-cancer activities. We assessed the mechanisms by which piceatannol inhibits inflammatory responses using lipopolysaccharide (LPS)-treated Raw264.7 murine macrophages. Piceatannol (0~10 ${\mu}mol/L$) decreased LPS-induced release of nitric oxide, tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-6, IL-$1{\beta}$, and inhibited LPS-induced protein expression of inducible nitric oxide synthase (iNOS). Activation of nuclear factor-kappaB (NF-${\kappa}B$), activator protein (AP)-1, and signal transducer and activator of transcription 3 (STAT3) are crucial steps during an inflammatory response. Piceatannol prevented LPS-induced degradation of inhibitor of ${\kappa}B$ ($I{\kappa}B$), translocation of p65 to the nucleus, and phosphorylation of stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK). Additionally, piceatannol inhibited LPS-induced phosphorylation of STAT3 and IL-6-induced translocation of STAT3 to the nucleus. Furthermore, piceatannol increased the protein and mRNA levels of hemeoxygenase (HO)-1, the rate-limiting enzyme of heme catabolism that plays a critical role in mediating antioxidant and anti-inflammatory effects. Piceatannol further induced antioxidant response elements (ARE)-driven luciferase activity in Raw264.7 cells transfected with an ARE-luciferase reporter construct containing the enhancer 2 and minimal promoter region of HO-1. These results suggest that piceatannol exerts anti-inflammatory effects via the down-regulation of iNOS expression and up-regulation of HO-1 expression.

Variation in Carotenoid Composition in Carrots during Storage and Cooking

  • Lim, Chae-Jin;Kim, Hyun-Young;Lee, Cheol-Ho;Kim, Yong-Ung;Back, Kyong-Whan;Bae, Jung-Myung;Lee, Shin-Woo;Ahn, Mi-Jeong
    • Preventive Nutrition and Food Science
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    • v.14 no.3
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    • pp.240-245
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    • 2009
  • High-performance liquid chromatography (HPLC) was applied to determine the carotenoid composition of carrots during storage and cooking. Analyses were conducted immediately after harvest and 1, 2, 4, and 8 weeks after harvest. During the course of the storage, the carotenoid levels generally decreased, and this decrease was found to be greater during the first week for $\beta$-carotene (all-trans-$\beta$-carotene) and lutein, and during the second week for $\alpha$-carotene. Additionally, the amount of the $\alpha-$ and $\beta$-carotenes in carrot leaves changed slightly within the first 2 weeks of harvest when stored at $4^{\circ}C$. Specifically, the level of lutein, the main component of carrot leaves, increased from 233.8$\pm$11.7 to $346.2\pm26.7{\mu}g$/g DW during the first 2 weeks. In addition, the change in carotenoid contents was observed during the home-processing of one Korean cultivar. Carrots fried in oil showed the highest amount of $\beta$-carotene ($164.3\pm6.6{\mu}g$/g DW) and $\alpha$-carotene ($50.1\pm0.4{\mu}g$/g DW), while carrots that were prepared by sauteing, pressure-cooking in water and microwaving had the second highest levels. The greatest loss of in carotenoids occurred in response to boiling in water containing 1% NaCl, braising and baking. The content of lutein increased slightly after boiling in water containing 1% NaCl ($9.3\pm0.4{\mu}g$/g DW), while a loss in lutein occurred after preparation using other home-processing methods. A cis-isomer of all-trans-$\beta$-carotene, 13-cis-$\beta$-carotene, was present in detectable amounts in all processed samples, but not in raw roots. Another isomer, 9-cis-$\beta$-carotene, was detected in carrots that were prepared by boiling, frying and pressure-cooking.

Individual and familial factors associated with youth sexual experience based on national sample survey (국가표본조사자료 기반 청소년 성경험의 개인 및 가족 요인 분석)

  • Hwang, Jinseub;Ryu, Jiin;Kim, Jiwon;Kim, Seokjoo
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.1
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    • pp.21-28
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    • 2017
  • This study aims to identify individual and familial factors associated with youth sexual experience by using the nationally representative sample data in South Korea. Specifically, we select 68,043 students in middle and high schools participating in the 2015 Korea Youth Risk Behavior Web-based Survey. Considering the complex survey design, we conduct a descriptive analysis and multiple logistic regression for sexual experience. The main results identify factors on sexual experience such as age, type of school, stress level, drinking, smoking, economic status, and cohabiting parents. In particular, the drinking and smoking behaviors are positively associated with sexual experience and the youth living with neither parent is more likely to have a sexual experience than those who lived two parents. In conclusion, the plan of sex education should consider the risk factors and the quality of sex education should be enhanced in order to build more appropriate sexual culture and behaviors among the youth.