• Korean Journal of Biological Psychiatry
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• v.24 no.2
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• pp.68-74
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• 2017

Objectives It is well known that problem drinking is associated with alterations of brain structures and functions. Brain functions related to alcohol consumption can be determined by the resting state functional connectivity in various resting state networks (RSNs). This study aims to ascertain the alcohol effect on the structures forming predetermined RSNs by assessing their cortical thickness. Methods Twenty-six abstinent male patients with alcohol dependence and the same number of age-matched healthy control were recruited from an inpatient mental hospital and community. All participants underwent a 3T MRI scan. Averaged cortical thickness of areas constituting 7 RSNs were determined by using FreeSurfer with Yeo atlas derived from cortical parcellation estimated by intrinsic functional connectivity. Results There were significant group differences of mean cortical thicknesses (Cohen's d, corrected p) in ventral attention (1.01, < 0.01), dorsal attention (0.93, 0.01), somatomotor (0.90, 0.01), and visual (0.88, 0.02) networks. We could not find significant group differences in the default mode network. There were also significant group differences of gray matter volumes corrected by head size across the all networks. However, there were no group differences of surface area in each network. Conclusions There are differences in degree and pattern of structural recovery after abstinence across areas forming RSNs. Considering the previous observation that group differences of functional connectivity were significant only in networks related to task-positive networks such as dorsal attention and cognitive control networks, we can explain recovery pattern of cognition and emotion related to the default mode network and the mechanisms for craving and relapse associated with task-positive networks.

• Korean Journal of Veterinary Research
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• v.53 no.1
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• pp.49-54
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• 2013

To investigate the transmission pattern of geographical area and temporal trends of the 2010~2011 foot-and-mouth disease (FMD) outbreaks in Korea, and to explore temporal intervals at which spatial clustering of FMD cases space-time analysis based on georeferenced database of 3,575 burial sites, from 30 November 2010 to 23 February 2011, was performed. The cases represent approximately 98.1% of all infected farms (n = 3,644) during the same period. Descriptive maps of spatial patterns of the outbreaks were generated by ArcGIS. Spatial Scan Statistics, using SaTScan software, was applied to investigate geographical clusters of FMD cases across the country. Overall, spatial heterogeneity was identified, and the transmission pattern was different by province. Cattle have more clusters in number but smaller in size, as compared to the swine population. In addition, spatiotemporal analysis and the comparison of clustering patterns between the first 7 days and days 8 to 14 of the outbreak revealed that the strongest spatial clustering was identified at the 7-day interval, although clustering over longer intervals (8~14 days) was also observed. We further discussed the importance of time period elapsed between FMD-suspected notice and the date of confirmation, and emphasized the necessity of region-specific and species-specific control measures.

• The Korean Journal of Cytopathology
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• v.5 no.1
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• pp.74-78
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• 1994

A case of retroperitoneal paraganglioma is presented with fine needle aspiration cytologic features. A 57-year-old woman complained of abdominal discomfort and left flank pain for 2 years. The abdominal CT scan revealed an ovoid mass left to the abdominal aorta. Percutaneous fine needle aspiration was performed from the mass. The smear revealed cellular sheets or groups on hemorrhagic background. The tumor cells were ovoid, round to spindle shaped with mild to moderate cellular pleomorphism. The nuclei were round to ovoid and had evenly dispersed chromatin and small nucleoli. The cytoplasm was amphophilic, finely granular and poorly defined. Cells having large or spindle nuclei were quite frequently observed, however, mitosis was not present The cytologic findings suggested paraganglioma, but the frequent spindle cell pattern and the pleomorphism made it difficult to exclude other endocrine tumors and sarcomas. The clinical, histological and ultrastructural findings as well as cytologic findings contributed to confirmatory diagnosis.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1993.05a
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• pp.90-90
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• 1993

When illustrating the therapeutical plan of laryngeal cancer, there are difficulties in obtaining the three dimensional volume of tumor, submucosal extension of tumor, and particularly whether or not invasion on laryngeal cartilage has occurred. In particular clinical significance is the invasion to the laryngeal framework, which correlates with poor prognosis due to high frequency of local recurrence and cervical metastasis. Therefore the purposes of histopathological evaluation according to serial section study after laryngectomy are firstly, apprehension of the spread of laryngeal cancer and the pattern of invasion to laryngeal cartilage and secondly, obtaining an aid to establish direction of management to make higher the validity of preoperative clinical diagnosis. The following results were obtained : 1. The pattern of tumor invasion in cartilage 1) The tumor invades ossified cartilage chiefly and invades nonossified cartilage in extensive lesion only. 2) The tumor spread through intramarrow space at invaded ossified cartilage with intact perichondrium. 3) The perichondrium is strong barrier. 2. The incidence of cartilage invasion in order of frequency is as follow thyroid, arytenoid, cricoid, epiglottic cartilage. 3. The transglottic cancer has higher incidence(811.8%)of cartilage invasion. 4. The sensitivity, specificity, and accuracy rate of preoperative CT scan was 100%, 62.5%, 82.3% respectively.

• Journal of Oral Medicine and Pain
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• v.22 no.1
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• pp.167-181
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• 1997

The aim of this study was to investigate the relationship between velocity and factors which could affect the velocity of mandibular movement. For this study, 30 dental students without any masticatory signs and symptoms and 90 patients with temporomandibular disorders(TMD) were selected as the control group and the patients group, respectively. After determining Angle's classification and lateral guidance pattern of occlusion, clinical examination for TMD was perfomed. Velocity and distance of mandibular movements were recorded with BioEGN, reproducibility index of lateral excursions was evaluated by Pantronic(PRI) and BioEGN (BERI) activity in masticatory and cervical muscles were measured with BioEMG, and occlusal contact time and cross-arch unbalance(Total left-right statistics, TLR) on clenching were recorded with T-scan, respectively. The results of this study were as follows : 1. Velocity in the patients was faster than that in the controls in most mandibular movements, but on wide opening and closing movement, result was reverse. 2. Velocity on closing movements were faster than that on opening movements in the control group and a similar tendency was also shown in the patients group. 3. Patients with muscle disorders showed a tendency to have the highest value of velocity of all diagnostic subgroups, while patients with degenerative joint diseases showed a tendency to have the lowest value. 4. Patients with canine guidance showed a tendency to have the highest value of velocity in three subgroups by lateral guidance pattern, while patients with group function showed a tendency to have the lowest value. 5. BERI had a positive correlation with opening velocity on lateral excursion, while TLR had a negative correlation with opening velocity on swallowing. 6. EMG activity on clenching in masticatory muscles had negative correlation with opening velocity on border movements, and on swollowing, while the activity in rest correlated positively with opening velocity on border movements. 7. There were positive correlation between the velocity and the distance in long components of mandibular trajectory.

• Tuberculosis and Respiratory Diseases
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• v.42 no.4
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• pp.624-628
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• 1995

Lymphangioleiomyomatosis is a rare disease which afflicts young women of childbearing age. We experienced a 32-year-old female who was admitted because of worsening exertional dyspnea after hormonal therapy with Clomifen for five months and intermittent hemoptysis. Chest PA showed diffuse ground glass appearance with some reticular infiltrations. High resolution CT scan showed multiple small thin walled cysts distributed homogeneously throughout the entire lung. Pulmonary function test showed characteristic obstructive pattern despite the restrictive interstitial pattern of chest radiography. Thoracoscopic lung biopsy specimen showed abnormal proliferation of smooth muscle cells in the walls of lymphatic vessels, bronchioles, and pulmonary vessels typical of pulmonary lymphangioleiomyomatosis. Hormonal therapy with medroxyprogesterone was initiated.

• Journal of Satellite, Information and Communications
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• v.9 no.2
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• pp.74-79
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• 2014

Conventional ScanSAR mode has been adopted in Envisat or Radarsat and played an important role to acquire wide swath SAR images for environmental surveillance. However, it suffers from the undesirable scalloping effect caused by non-homogeneity of antenna pattern while the image resolution is sacrificed. In recent years, TOPS mode has been suggested and put into use to overcome the disadvantages of the conventional scanning mode. Although TOPS mode is able to produce wide-swath SAR image in a short time interval, it demands highly complicated system design knowledge. In this paper, we present the operation principle of TOPS mode and a full SAR simulation is performed to generate TOPS SAR raw data. Azimuth antenna pattern is modified during TOPS mode operation and it is shown that the undesired scalloping effect is suppressed in the generated SAR image.

• The Journal of Korean Academy of Prosthodontics
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• v.31 no.1
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• pp.63-76
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• 1993

The purpose of this study was to investigate the disclusion time and occlusal pattern during lateral movement in normal group and temporomandibular dysfunction (TMD) group. Twenty dental college students of Chosun University without the abnormal occlusion and temporomandibular dysfunction were selected as a normal group, and twenty slight temporomandibular dysfunction (TMD) group and the ten moderate temporomandibular dysfunction (TMD) group classified according to Helkimo's dysfunction index were selected. Occlusal pattern was classified as canine guided occlusion, group functioned occlusion and the other group during lateral movement and disclusion time in lateral movement was measured using T-Scan system. The result were as follows: 1. The disclusion time according to each group were $1.24{\pm}0.58$ sec in normal $1.60{\pm}0.79$ sec in slight TMD group and $2.29{\pm}0.80$ sec in moderate TMD group. There was statistically significant between normal group and moderate TMD group(P<0.01), slight TMD group and moderate TMD group(P<0.05). 2. The distribution of occlusal pattern in normal group was 62.5% (25 side) in canine guided occlusion, 27.5% (15 side) in group functioned occlusion. 3. The distribution of occlusal pattern in slight TMD group was 45% (18side) in canine guided occlusion, 35% (14 side) in group functioned occlusion and 20% (8side) in others and that in moderate TMD group was 15% (3 side) in canine guided occlusion, 35% (7 side) in group funcconed occlusion and 50% (10 side) in other 4. The disclusion time in normal group was $1.05{\pm}0.59$ sec at canine guided occlusion and $1.53{\pm}0.72$ sec at group functioned occlusion. 5. The disclusion time in slight TMD group was $1.23{\pm}0.75$ sec in canine guided occlusion, $1.50{\pm}0.88$ sec in group functioned occlusion, and $2.61{\pm}0.57$ sec, in the other. There was staistically significant between canine guided occlusion and other(P<0.001)and group functioned occlusion and the other (P<0.05). 6. The disclusion time in moderate TMD group was $1.28{\pm}0.84$ sec in canine guided occlusion, $1.75{\pm}0.58$ sec in group functioned occlusion, and $2.98{\pm}0.08$ sec in the other(P<0.01).

• Journal of Applied Biological Chemistry
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• v.63 no.1
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• pp.29-33
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• 2020

The objective of this study was to develop a fast and accurate method of variety discrimination and geographical discrimination origin of Korean angelica (Korean variety, Angelica gigas Nakai) by using TDU-GC/MS. Two peaks of decursin and decursinol, which are coumarin derivatives were identified in the range of Total Ion Chromatogram (TIC) RT 26.9-27.2 of the Korean angelica by GC/MS analysis at the time of condensation in a refrigerated condensation system after thermal desorption of sample extracts. In case of Chinese angelica (Chinese variety), ligustilide peak was detected at the RT 17.2. In order to investigate the difference of volatile components according to the geographical origin of Korean variety, the mass spectra were measured by TDU-GC/MS at the range of m/z 40-400 amu. The TIC of domestic cultivation and Chinese cultivation of the Korean variety, Angelica gigas Nakai showed the same tendency as a whole. However, in partial scans of TIC, two peaks detected at 15.54 and 16.05 of RT showed different peak patterns between Korean angelica (Korean variety) cultivated in Korea and in China. The ratio of Peak A (RT 15.54) and B (RT 16.05) was 0.0-0.2 for domestic cultivation and 0.5-2.8 for Chinese cultivation, confirming the possibility of discriminating origin by comparing the TIC peak pattern of TDU-GC/MS.

• Fashion & Textile Research Journal
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• v.19 no.6
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• pp.749-758
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• 2017

The purpose of the present study is to develop a grading deviation, which is appropriate for the body type of women in thirties, by analyzing the three-dimensional body type. The materials for the study were adopted from the body measurement data of women in the age group of 30 to 39 years old, provided from Size Korea. By reflecting the factor analysis results using the three-dimensional shape measurement, deviations were derived. First, six factors influencing the changes in human body shape were derived as waist-hip length factor, bust-waist shape factor, back protrusion back shoulder factor, bust length factor, shoulder length factor, and frontal waist dart factor. The bust size and height, which can be easily utilized for the top original grading, were used for deriving a regression formula, and the deviation was set in accordance with the result. Second, by applying the deviation which reflects the changes in the body shape, the crimps which were generated due to the application of existing deviation were remarkably reduced, indicating that the grading of the present study is more fitting than the existing one. The deviation derived by the analysis of actual increase and decrease of body size was more fitting than the existing one. This was proved by actual wearing experiment, which represents the significance of this study.