• The Korean Journal of Applied Statistics
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• v.28 no.2
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• pp.295-308
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• 2015

We have experienced a substantial improvement in and cost-drop for genotyping that enables genetic epidemiological studies with large-scale genetic data. Genome-wide association studies have identified more than ten thousand causal variants. Many statistical methods based on linear mixed models have been developed for various goals such as estimating heritability and identifying disease susceptibility locus. Empirical results also repeatedly stress the importance of linear mixed models. Therefore, we review the statistical methods related with to linear mixed models and illustrate the meaning of their estimates.

• Nuclear Engineering and Technology
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• v.49 no.6
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• pp.1310-1317
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• 2017

GASFLOW-MPI is a widely used scalable computational fluid dynamics numerical tool to simulate the fluid turbulence behavior, combustion dynamics, and other related thermal-hydraulic phenomena in nuclear power plant containment. An efficient scalable linear solver for the large-scale pressure equation is one of the key issues to ensure the computational efficiency of GASFLOW-MPI. Several advanced Krylov subspace methods and scalable preconditioning methods are compared and analyzed to improve the computational performance. With the help of the powerful computational capability, the large eddy simulation turbulent model is used to resolve more detailed turbulent behaviors. A backward-facing step flow is performed to study the free shear layer, the recirculation region, and the boundary layer, which is widespread in many scientific and engineering applications. Numerical results are compared with the experimental data in the literature and the direct numerical simulation results by GASFLOW-MPI. Both time-averaged velocity profile and turbulent intensity are well consistent with the experimental data and direct numerical simulation result. Furthermore, the frequency spectrum is presented and a -5/3 energy decay is observed for a wide range of frequencies, satisfying the turbulent energy spectrum theory. Parallel scaling tests are also implemented on the KIT/IKET cluster and a linear scaling is realized for GASFLOW-MPI.

• Proceedings of the Korean Vacuum Society Conference
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• 2000.02a
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• pp.147-147
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• 2000

Chemisorption of oxygen molecules on the Si(111)-(7x7) surface has been studied extensively as a model for the initial-stage oxidation of the surface. The basic step to the surface oxidation is the dissociation of the adsorbed O2 molecules, but the dissociation procedure and the atomic structure of the reaction products still remains as a subject of debates. We present here density-functional theory calculations on the initial-stage oxidation states of the Si adatom site for all possible dissociation configurations that can be generated by multiple O2 reactions. We determine the equilibrium structures and analyze their electronic and vibrational properties in comparison with measured UPS, XPS, and EELS spectra. The O(ad) atom bonded on top of the Si adatom is always less stable than the O(ins) atom inserted into one of the adatom backbonds. Our electronic and vibrational analysis demonstrates further that the O(ad) and O(ins) atoms account well for the metastable and stable features in previous experiments, respectively. Moreover, the calculated decay pathways of the metastable structures and the comparison of the calculated O ls core-level shifts with XPS data provides a convincing argument in unambiguously identifying the experimental metastable and stable structures, thereby making it possible to build a correct atomic-scale picture of the initial-stage oxidation process on this surface.

• Proceedings of the Korea Water Resources Association Conference
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• 1997.05a
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• pp.192-198
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• 1997

The spatial variation of saturation tendency can be calculated from the Digital Elevation Model (DEM) employing the multiple flow direction algorithm on the platform of Geographic Resources Support Analysis System (GRASS). It is expected that a bettter understanding of dynamical runoff processes in hillslope hydrological scale is obtained through tracing various runoff path such as infiltration excess overland flow component, strutation excess overland flow component and subsurface runoff component. A procedure is suggested to consider the effect of a tile system on calculating the topographic index. A small agricultural subwatershed (3.4 km2) is used for this study.

• Journal of Korea Water Resources Association
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• v.31 no.3
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• pp.243-252
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• 1998

In this study, the new dimensionless values were defined and proposed to determine the parameters of urban runoff models based on the relative sensitivity analysis. Also, the sensitivity characteristics of each parameter were investigate. In order to analyze the parameter sensitivities of each model, total runoff ratio, peak runoff ratio, runoff sensitivity ratio, sensitivity ratio of total runoff, and sensitivity ratio of peak runoff were defined. $$Total\;runoff\;ratio(Q_{TR})\;=\;\frac{Total\;runoff\;of\;corresponding\;step}{Maximum\;total\;runoff}$$$$Peak\;runoff\;ratio(Q_{PR})\;=\;\frac{Peak\;runoff\;of\;corresponding\;step}{Maximum\;peak\;runoff}$$$$Runoff\;sensitivity\;ratio(Q_{SR})\;=\;\frac{Q_{TR}}{Q_{PR}}$$ And for estimation of sensitivity ratios based on the scale of basin area, rainfall distributions and rainfall durations in ILLUDAS & SWMM, the reasonable ranges of parameters were proposed.

• Plant Biotechnology Reports
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• v.2 no.1
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• pp.47-58
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• 2008

To select agronomically useful transgenic plants, a large number of transgenic events are initially produced, gene transfer confirmed, and advanced to obtain homozygous lines for testing in field trials. Direct in planta assays for identifying the transgene carriers in the segregating progeny are based on the activity of selectable marker gene and are easy, simple and inexpensive. For this purpose, expression of bar gene as measured by tolerance to damage by glufosinate ammonium, the active ingredient in the herbicide BASTA, was investigated. Dose damage curves were generated by leaf paint tests with BASTA on four genotypes of sorghum. Transgenic plants were characterized in terms of sensitivity to the concentration of glufosinate ammonium. In transgenics, symptoms of BASTA swab tests at different growth stages and PCR analysis for cry1B were carried out and correlated. Germination tests could not be employed for large scale evaluation of transgenic progeny because of mortality of tolerant seedlings after transplantation to soil. Based on the above findings, a simple, inexpensive, time-saving, two-step scheme for effective evaluation of transgenics and their progeny containing bar gene as selection marker using BASTA swab tests is described.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.681-684
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• 2005

The old technique of sandblasting which has been used for paint or scale removing, deburring, and glass decorating has recently been developed into a powder blasting technique for brittle materials, capable of producing micro structures larger than 100um. A large number of Investigations on the abrasive jet machining with output parameters as material removal rate, penetrate and surface finish have been carried out and reported by various authors. In this paper, we investigated the effect of surface characteristics and surface shape of the abrasive jet machined glass surface under different blasting parameter. and finally we established a model for abrasive flow machining process, and compared with experimental results.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.9
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• pp.707-714
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• 2016

This paper describes analysis results of vibration characteristics and modal test for a small-scale quad-rotor drone. The rotor arm has a slender body with a propeller and motor at its tip. Rotor system generates excitation for an unbalanced mass. Therefore, the drone platform is involved in the possibility of resonance. For advance identification of the possibility of resonance, confirmation of eigen-mode being closest to the propeller operation range is necessary. Material properties of CFRP tubes used for the rotor arm were acquired by finding the natural frequency based on Rayleigh method. A simplified quad-rotor FE model consisting of rotor arm assembly with tip mass was built to perform numerical analysis, and a free-free boundary condition was applied to provide flight status. Modal tests for the actual platform with impact hammer instrument were performed to verify analysis results. Separation margin from hazardous eigen-mode was checked on the propeller operation range.

• Journal of Mechanical Science and Technology
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• v.19 no.6
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• pp.1366-1377
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• 2005

Experimental study was carried out in an atmospheric pressure, laboratory-scale dump combustor showing features of combustion instabilities. Flame structure and heat release rates were obtained from OH emission spectroscopy. Qualitative comparisons were made between line-integrated OH chemiluminescence image and Abel-transformed one. Local Rayleigh index distributions were also examined. Mean temperature, normalized standard deviation and temperature fluctuations were measured by coherent anti-Stokes Raman spectroscopy (CARS). To see the periodic behavior of oscillating flames, phase-resolved measurements were performed with respect to the pressure wave in the combustor. Results on system damping and driving characteristics were provided as a function of equivalence ratio. It also could be observed that phase resolved temperatures have been changed in a well-defined manner, while its difference between maximum and minimum reached up to 280K. These results would be expected to play an important role in better understanding of driving mechanisms and thermo-acoustic interactions.

• Korean Journal of Organic Agriculture
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• v.3 no.1
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• pp.11-22
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• 1994

Exposing plant organs to high doses of ionizing irradiation, penetrating into the plant tis-sues and cells, along the track structure of particles, lesions, and sublesions are formed on the molecules and organelles. As a result, disorders in the growth and development as well as chlorophyll-deficiency symptoms occur. The time scale of their reparation, recovery and over compensation during ontogenesis, constitutes a question of high theoretical and practical importanced, with special regard to nuclear fallout. With an aim to model the “ut supra”stated phenomena, the seeds of bean, Echo elit licensed variety, were irradiated by 300 Gy dose of X-ray-irradiation (120 kV:4.5 mA). According to the data obtained, the biosynthesis of photosynthetic pigments, will have been completed by the beginning of flowering. In consequence of the overcompensation of the repairing processes, the organs of plants developed from irradiated seeds, showed a partly differing correlative growth, compared to those of control plants. In order to characterize the vivo response of radiation-injured plants, a new method and approach were used. The changes of the electric capacitance of the plants during their ontogenesis, were continously monitored and recorede via a computer-aided and controlled measurement. In view of the data collected in such a way, the repairing plants may respond more quickly and intensively to the changes of environmental factors.