• Journal of the korean veterinary medical association
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• v.46 no.3
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• pp.245-263
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• 2010

말 원충성척수뇌염(equine protozoal myeloencenphalitis; EPM)은 말에게 심각한 신경성 질병을 일으키는 원충성 질병으로서 Sarcocystis neurona가 원인체이다. 근육포자낭(sarcocyst)을 숨기고 있는 자연중간숙주를 포함한 S. nuerona의 완전한 생활사는 알려져 있지 않으나 주머니쥐의 일종인 opossum(Didelphis virginiana, Didelphis albiventris)이 최종 숙주이며, 말은 정상적 숙주로 알려져 있다. 왜냐하면 말에서는 분열체(schizonts)와 분열소체(merozoites)가 발견되기 때문이다. EPM 유사 질병들이 고양이, 밍크, 너구리, 스컹크, 태평양 점박이 바다표범, 포니, 바다수달 등을 포함한 다양한 포유류에서 발생한다. 고양이는 포자낭(sporocytes) 섭식 후 근육포자낭 단계를 숨기는 실험적인 중간숙주로서 역할을 할 수 있다. 최근 국내에서 신경증상을 나타내는 말에 대한 의심스러운 임상증상이 임상수의사들에 의해 관찰되어졌는, 정확한 진단을 하기위하여 S. nuerona에 의해 발생된 EPM의 역사, 구조, 생활사, 생물학, 병리론, 동물에서 질병 유도, 임상 증상, 진단, 병인론, 생태학, 치료 등에 대하여 알아보고자 한다.

• Korean Journal of Veterinary Research
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• v.29 no.3
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• pp.325-331
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• 1989

Five hundred and forty-eight samples of pig heart muscle were collected from the abattoirs of many regions in Korea to reveal the frequency of Sarcocystis infections and to identify the species from June 1988 to April 1989. Heart muscle of the pigs was inspected for sarcocysts by the direct detection technique and for bradyzoites by the trypsin digestion technique. For examination of development of the parasites in the final host, 5 cross bred mature dogs, 5 puppies and 5 kittens were fed 100g, 50g and 50g of the infected meat respectively, four times in 2 days. Of 402 fattened and 146 older culled breeding pigs, 3 fattened pigs and 39 culled pigs were positive for Sarcocystis. Sarcocystis cysts from heart muscle measured an average of $425{\times}169{\mu}m$ and bradyzoites an average of $15.6{\times}3.5{\mu}m$. Of 15 animals, only 2 puppies were infected with Sarcocystis. The prepatent period was 11 to 12 days and patent period was not examined since the puppies were infected with some another infections and one died on day 11 and another died on day 12 after ingestion of the meat. The sporulated oocysts were detected 11 days after ingestion of the meat and sporocysts 12 days from the puppy feces. The sporulated oocysts measured an average of $16.5{\times}11.5{\mu}m$ and sporocysts an average of $12.6{\times}7.9{\mu}m$. On scraping examination of the intestinal mucosa, fully sporulated oocysts were detected in the tip of the intestinal villi. Considering above all descriptions, Sarcocystis in pig heart muscle in Korea was identified with Sarcocystis suicanis.