• Korean Journal of Agricultural Science
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• v.47 no.4
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• pp.1021-1027
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• 2020

The amount of food waste generated in Republic of Korea has been increasing alongside an increasing population and booming economy as such, research on effective treatment and recycling is required. Food waste recycling is complicated by its inferior characteristics such as high levels of water and concern that its continuous application to farmland can lead to salt accumulation and concomitant damage crops. In the present study, therefore, dehydrated food waste powder (FWP), which contains a large amount of organic matter and nutrients, but which may require additional improvements was mixed in various ratios with organic fertilizers and the mixtures were tested for their effects on the growth of the leaf lettuce. A control was set up with inorganic fertilizers alone while a treatment with only FWP was also included. The mixture of FWP and organic fertilizers produced better leaf lettuce growth in all the treatments than the control and FWP. The fresh weight of the leaf lettuce produced with a mixture containing 60% FWP was 50% higher than that of the control. The results from this study indicate, therefore, that FWP mixed with other organic supplements in appropriate amounts positively impacts crop growth and development.

• Nutrition Research and Practice
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• v.16 no.1
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• pp.132-146
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• 2022

BACKGROUND/OBJECTIVES: Various sodium reduction policies have been implemented. However, there are limitations in the aspect of actual field applicability and efficiency. For effective sodium reduction, cooperation with the field is required and consumer preference must be considered. Thus, this study aimed to develop a low-sodium burger considering field applicability and consumer preference. MATERIALS/METHODS: Focus group interviews and in-depth interviews on the sodium reduction measures were conducted with nine professionals in related fields to discuss practical methods for sodium reduction from September 7 to 21, 2018. By reflecting the interview results, a burger using a low-sodium sauce was developed, and preference analysis for sodium in the burger sauces and finished products was performed. The consumer preference for low-sodium burgers was evaluated on 51 college students on November 12, 2018. RESULTS: The results of the professional interview showed that it is desirable to practice sodium reduction gradually, and by reflecting this, the burger sauce was prepared by adjusting the ratio of refined salt to 15%, 30%, and 50%. The sodium content of the burger using low-sodium sauce was 399 mg/100 g in the control group, 362 mg/100 g in the H1 group, and 351.5 mg/100 g in the H2 group, showing a 9.3-11.9% decrease in sodium in the H1 and H2 groups. The preference evaluation on the low-sodium burgers showed a higher preference for burgers with 9.3-11.9% sodium reduction, which did not affect the overall taste. CONCLUSIONS: This study examined the potential for sodium reduction in the franchise foodservice industry. An approximate 10% sodium reduction resulted in an increase in consumer preference without affecting the strength of the taste. Thus, if applied gradually, sodium reduction at practical levels could increase the consumer preference without changing the taste or quality and could be applied in the franchise foodservice industry.

• The Korea Journal of Herbology
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• v.24 no.2
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• pp.49-56
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• 2009

Objectives : Inflammation is important event in the development of vascular diseases including hypertension, atherosclerosis, and restenosis. Bodusan (BDS) was a traditional Korean herbal medicine and widely used in treatment of gastrointestinal complaint and stomach ulcer. The aim of this study was to determine whether BDS and its components inhibit production of nitrite, PGE2 and proinflammatory cytokines in lipopolysaccharide (LPS)-treated RAW 264.7 macrophages. Methods : Cytotoxic activity of BDS and its components on RAW 264.7 cells was using 5-(3caroboxymcrophages. eth-oxyphenyj)-2H-tetra-zolium inner salt (MTS) assay. The nitric oxide (NO) production was measured by Griess reagent system. And proinflammatory cytokines were measured by ELISA kit. The levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression were detected by western blot. Results : Our results indicated that BDS and its components significantly inhibited the LPS-induced NO and PGE2 production. Moreover. BDS and its components inhibited iNOS and COX-2 expression accompanied by an attenuation of TNF-${\alpha}$, IL-11${\beta}$, IL-6 and MCP-1 formation in macrophages. Conclusions: These results indicate that BDS and its components have potential as an anti-inflammatory agent.

• Animal Bioscience
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• v.36 no.7
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• pp.1120-1129
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• 2023

Objective: This study aimed to determine the protective efficacy of Buddha's Temple (BT) extract against tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in Gallus gallus chicken embryo fibroblast cell line (DF-1) and its effects on the cell lipid metabolism. Methods: In this experimental study, Gallus gallus DF-1 fibroblast cells were pretreated with BT 10^-7 for 24 hours, followed by their six-hour exposure to t-BHP (100 μM). Water-soluble tetrazolium salt-8 (WST-8) assays were performed, and the growth curve was computed. The intracellular gene expression changes caused by BT extract were confirmed through quantitative polymerase chain reaction (qPCR). Flow cytometry, oil red O staining experiment, and thin-layer chromatography were performed for the detection of intracellular metabolic mechanism changes. Results: The WST-8 assay results showed that the BT pretreatment of Gallus gallus DF-1 fibroblast cell increased their cell survival rate by 1.08%±0.04%, decreased the reactive oxygen species (ROS) level by 0.93%±0.12% even after exposure to oxidants, and stabilized mitochondrial activity by 1.37%±0.36%. In addition, qPCR results confirmed that the gene expression levels of tumor necrosis factor α (TNFα), TIR domain-containing adapter inducing IFN-beta (TICAM1), and glucose-regulated protein 78 (GRP78) were regulated, which contributed to cell stabilization. Thin-layer chromatography and oil red O analyses showed a clear decrease in the contents of lipid metabolites such as triacylglycerol and free fatty acids. Conclusion: In this study, we confirmed that the examined BT extract exerted selective protective effects on Gallus gallus DF-1 fibroblast cells against cell damage caused by t-BHP, which is a strong oxidative inducer. Furthermore, we established that this extract significantly reduced the intracellular ROS accumulation due to oxidative stress, which contributes to an increase in poultry production and higher incomes.

• Korean Journal of Exercise Nutrition
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• v.23 no.4
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• pp.6-13
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• 2019

[Purpose] In this study, we examined the in vitro antioxidant activities and laxative effects of taurine-xylose (T-X), a synthetic taurine-carbohydrate derivative, in a rat model of constipation induced by loperamide. [Methods] The animals were divided into four treatment groups: normal untreated rats (NOR group), loperamide-treated control rats (CON group), loperamide and taurine-xylose (15 mg/kg)-treated rats (T-X group), and loperamide and commercial Dulcolax S (5.5 mg/kg)-treated rats (DS group). [Results] In the present study, T-X exhibited potent reducing power and free radical scavenging activities for DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS+ (2,2'-azino-bis (3-ethylbenzothiazoline 6-sulfonic acid ammonium salt) radicals. The laxative effects of T-X were dependent on food, body weight, fecal properties, gastrointestinal transit (GIT) ratio, and serum metabolic parameters. In the T-X group, the number, wet weight, and water content of fecal pellets were noticeably increased compared to those in the loperamide-induced group. T-X treatment significantly increased the activities of hepatic antioxidant enzymes, including those of glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT), relative to those in loperamide-induced constipated rats. Furthermore, the GIT ratio and loperamide-induced metabolic parameters in serum, including gastrin (GAS), motilin (MTL), and somatostatin (SS) levels, were significantly improved by T-X treatment. [Conclusion] These results suggest that taurine-xylose exerts antioxidant activities and laxative effects on loperamide-induced constipation by promoting gastrointestinal motility.

• Animal Bioscience
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• v.37 no.6
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• pp.1130-1139
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• 2024

Objective: The daily maximum temperature and seawater level continuously increase as global warming continues. We examined the adaptability and production performance of heat-stressed goats with a supply of low-saline drinking water. Methods: Twelve Kacang and Kacang Etawah cross goats were exposed to two climatic conditions (control, 25℃ to 33℃, 83% relative humidity [RH], temperature humidity index [THI]: 76 to 86; and hot environment, 26℃ to 39℃, 81% RH, THI: 77 to 94) and two salt levels in drinking water (0% and 0.4% NaCl). The experimental design was a Latin Square (4×4) with four treatments and four periods (28 days each). Results: Temperature of the rectal, skin, and udder, and respiration rate rose, reached a maximum level on the first day of heat exposures, and then recovered. Plasma sodium rose at 0.4% NaCl level, while the hot environment and salinity treatments increased the drinking water to dry matter (DM) intake ratio. Water excretion was elevated in the hot environment but lowered by the increase in salinity. Total lying time increased, whereas change position frequency decreased in the hot condition. Lying and ruminating and total ruminating time increased and explained the enhanced DM digestibility in the hot conditions. Conclusion: The goats exhibited a high level of plasma sodium as salinity increased, and they demonstrated physiological and behavioral alterations while maintaining their production performances under increasing daily maximum temperatures.

• The Korea Journal of Herbology
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• v.39 no.1
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• pp.39-47
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• 2024

Objectives : This study evaluates how various traditional Korean herbal medicines assess MUC5AC expression for esophageal mucosal defense and analyzes the associated mechanisms involved in inflammation. Methods : Forty types of traditional Korean herbal medicines were assessed for in vitro antioxidant activities, and the real-time PCR method was employed to analyze MUC5AC expression under pH 4.5 conditions in human esophageal epithelial cells (HET-1A). Eight types of Korean herbal medicines were evaluated for in vitro antioxidant activities, and Reactive oxygen specise (ROS) expression was analyzed under bile salt (480 𝜇M) and pH 5.5 conditions in human esophageal epithelial cells (HET-1A). Simulation experiments involving bile salts and acidity were conducted for one hour to assess the efficacy of four drugs, and the activities of Mitogen-activated Protein Kinase (MEK), Nuclear Factor Kappa B (NF-𝜅B), and Cyclooxygenase-2 (COX-2) were detected through Western blot analysis. Results : Compared to the Normal group, the Control group exhibited higher ROS generation. Such increased ROS levels were significantly reduced by four extracts: Citrus Unshius Pericarpium (CUP), Cnidium officinale Rhizoma (CR), Ginseng Radix (GR), and Linderae Radix (LR). The protein expression of COX-2 decreased with the treatment of LR, CUP, and CR. Particularly, CUP and CR exhibited superior effects compared to other groups in inhibiting the phosphorylation of NF-𝜅B. Conclusion : Based on the results obtained, we have identified drugs that inhibit oxidative stress and inflammation caused by bile acid in esophageal epithelial cells. Our future plans involve comparing and analyzing the efficacy of these herbal medicines through animal experiments.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.26 no.1
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• pp.69-75
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• 2022

Backgrounds/Aims: Progressive familial intrahepatic cholestasis (PFIC) is an autosomal recessive inherited disease requiring liver transplantation (LT). The objective of this study was to investigate the clinicopathological features and posttransplant courses of seven LT recipients with PFIC. Methods: This was a retrospective single-center study of patients with PFIC who underwent LT from January 2013 to June 2020. Results: Two and five patients were diagnosed with PFIC type 1 and type 2, respectively. For all seven patients, age of PFIC onset was at birth. Jaundice was present in all cases. Mean pretransplant total and direct bilirubin levels were 16.1 ± 8.1 mg/dL and 12.4 ± 6.2 mg/dL, respectively. Median patient age and body weight at LT were 10 months and 7 kg, respectively. Types of donors were mothers of patients in four and deceased donors in three. All five patients with PFIC type 2 recovered uneventfully. One patient each with PFIC type 1 underwent retransplantation due to graft failure or died due to multi-organ failure. Overall graft and patient survival rates at five years were 66.7% and 83.3%, respectively. Bile salt export pump immunohistochemical staining showed normal canalicular expression in two patients with PFIC type 1, focal loss in two patients with PFIC type 2, and total loss in three patients with PFIC type 2. Conclusions: LT is currently the only effective treatment for PFIC-associated end-stage liver diseases. It is mandatory to perform regular follow-up due to the risk of complications including steatohepatitis, especially for patients with PFIC type 1.

• Journal of the Korea Institute of Building Construction
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• v.24 no.5
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• pp.541-552
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• 2024

This study introduces a new analytical model known as the Cellular Automaton Method(CAM) designed to predict the degree of deterioration in concrete, taking into account its complex pore structure. The CAM model assesses the impacts of moisture migration, driven by capillary action and pressure differentials at the gas-liquid interface, which are influenced by the distribution of pores. It also evaluates how porosity and diffusion coefficients affect the penetration of chloride ions. The model's application revealed distinct moisture movement patterns in concrete structures, distinguishing between those with porosity levels below and above 40 percent. Additionally, it facilitated a comparison and analysis of chloride ion diffusion phenomena, based on diffusion coefficients in areas penetrated by moisture, against results obtained from the Finite Element Method(FEM). The comparison showed a maximum deviation of only 0.989 percent between the predicted outcomes of the FEM and CAM, demonstrating substantial agreement and validating CAM's efficacy in simulating the diffusion processes of chloride ions within concrete under actual salt damage conditions. Thus, CAM proves to be a reliable tool for modeling and anticipating deterioration in concrete structures exposed to saline environments.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.57 no.3
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• pp.203-208
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• 2012

Field experiment was carried out to identify the proper water exchange interval for the rice cultivation on reclaimed saline soil with different nitrogen levels in southwestern area. The nitrogen fertilizer was applied 14, 17 and 20 kg per 10a by ingredient, and intervals of water exchange treated 3, 6 and 9-day periods from transplanting of rice(Oryza sativa var. Cheongho) to maturing stage in Munpo soil series. The salinity levels ranged 0.10~0.24% and 0.24~0.32% of 3-day and 6-day respectively, whileas it ranged 0.35~0.52% for 9-day interval of water exchange during vegetative stage. Water exchange and nitrogen level showed significant effects on the plant growth, yield, and quality. The yield of milled rice on 3-day and 6-day interval of water exchange showed 497 kg/10a and 492 kg/10a and that were significantly higher than that of 9-day interval in 2008 and 2009. Milled rice yield of 9-day interval of water exchange was lower than that of 3-day and 6-day interval of all nitrogen levels. Plant growth and yield components were not significantly different between 3-day and 6-day interval of water exchange of all nitrogen levels. The combination of nitrogen fertilizer level of 17 kg/10a and 6-day interval of water exchange after transplanting might be recommended for maximum yield realization and minimize salt injury at reclaimed medium saline soil in southwestern area.