• YAKHAK HOEJI
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• v.31 no.2
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• pp.82-91
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• 1987

The effect of neurotoxic compound 6-hydroxydopamine (6-OHDA) on the change in blood pressure and contractile response of Vas deference by centrally acting agents has been studied in normal and DOCA-salt induced hypertensive rats. The treatment of neonatal rats with 6-OHDA (2$\times$100mg, 250mg Kg$^{-1}$s.c) significantly inhibited the antihypertensive and relaxant effects of Vas deference of clonidine(100$\mu\textrm{g}$ Kg$^{-1}$iv.). The simultaneous administration of desipramine with clonidine into neonatal rats decreased the antihypertensive response of clonidine although treated did not affect the relaxative response of Vas deference. Furthermore, the antihypertensive and relaxant responses of clonidine were reduced by the neonatal rats with 6-OHDA regardless of the administration of desipramine. When neonatal rats were administered with 6-OHDA, the development of DOCA-salt hypertension was prevented. These results suggest that 6-OHDA, clonidine and desipramine hada significant effect on the development and the inhibition of central hypertension mediating the central adrenergic neuron due to their affinity to the central nervous system.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1996.11a
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• pp.326-329
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• 1996

In order to synthesize Ba-ferrite fine particles by molten salt method and inhibit the abnormal grain growth of sintered specimen, KCI anti NaCl were added to basic composition to 50% by weight, and added 1 male% of $SiO_2$ to control the shape of Ba-ferrite particles. $H_{c}$ and $M_{r}$ were decreased when F $e^{3+}$ was substituted with $Co_{2+}$ and $Ti_{4+}$ from x=0 to x=1.0 in $BaFe_{12-2x}$ $Ti_{x}$ $Co_{x}$ $O_{19}$ , and 1 mole% $SiO_2$ increased the size but shortened c-axis of hexagonal ferrite. Seeds added in Ba-ferrite particle effected inhibition of abnormal grain growth during sintering.ing.g.

• Archives of Pharmacal Research
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• v.8 no.4
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• pp.267-272
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• 1985

Pyrantal pamoate's anthelmintic activity is due to its action as a neuromuscular blocking agent. It is generally well tolerated. Transient rises in SGOT levels have been reported in the drug-treated patients. Decreased levels of serum alkaline phosphatase post treatment were found in yound dogs. The present study was performed to investigate the possible toxic effects of pyrantal pamoate in pregnant mice progenies. The drug was given in different doses to these mothers in the first, second and third trimester. Serum alkaline phosphatase, SGOT and SGPT of one or two month old offspring were monitored. SGOT levels showed an increase in some doses in one and two month old offspring where alkaline phosphatase showed a decrease in some doses in one and two month old offspring. The latter effect may be due to osteoblastic alkaline phosphatase inhibition. The effect on SGOT levels, however, was difficult to explain, but may be due to a toxic effect on liver cells or cardiac muscles.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.235.3-236
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• 2003

S-adenosyl-L-homocysteine(AdoHcy) is the product of all biological methylation in which S-adenosyl-L-methionine (AdoMet) is utilized as a methyl donor and is reversibly hydrolyzed to L-homocysteine and adenosine by AdoHcy hydrolase physiologically. Inhibition of this enzyme results in intracelluar accumulation of AdoHcy leading to a feedback inhibition of AdoMet-dependent methylation reactions which are essential for viral replication. (omitted)

• Corrosion Science and Technology
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• v.6 no.2
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• pp.68-73
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• 2007

The toxicity of chromium that is used to impart corrosion resistance to galvanized steel created environmental and health-related concerns and generated a great deal of interest in developing chrome-free treatment coatings. In the present work, organic-inorganic composite coatings were used to coat electrogalvanized steel (EG) sheets for corrosion protection without degrading its weldability property. The new coatings composed of specially modified polyurethane dispersion hybridized with silicate and unique inorganic-organic inhibitors were developed during this work. It was found that about $1{\mu}m$ thickness of coating layer is secure enough in corrosion resistance of flat and formed part even after alkaline degreasing. Overall chemical resistances including fingerprint resistance and paint adhesion property were satisfied with the test specification of Sony technical standard of SS-00260-2002. Therefore, it is concluded that the newly developed chrome-free product can replace the conventional chromated product.

• Journal of the Korean Society of Tobacco Science
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• v.26 no.1
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• pp.7-12
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• 2004

Effect of Decyl Alcohol Emulsifiable Concentrate on sucker control and phytotoxicity to tobacco plants were tested on flue-cured tobacco and burley tobacco. There were no significant differences of sucker inhibition effect between Decyl Alcohol EC and Choline Salt of Maleic Hydrazide Soluble Concentrate(control chemical). Tobacco plants applied with Decyl Alcohol EC showed no visible symptoms of phytotoxicity and no significant differences of number of leaves, leaf length, leaf width, and stalkt height. Yields increased considerably with no difference from ones of plants treated with control chemical.

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2001.12a
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• pp.161-169
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• 2001

Lactic acid producing bacteria were isolated from baby feces and characterized to be used as a probiotic with anti Helicobacter pylori functions. The selected bacteria had inhibition activity on the adherance and growth of H. pylori. These bacteria had additional beneficial characteristics for the probiotic such as antibacterial activity, antitumor activity, immunostimulation activity, resistance to antibiotic and bile salt, ability to bind to the intestinal cells, and safe for the human use.

• Proceedings of the Korea Concrete Institute Conference
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• 2002.10a
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• pp.63-67
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• 2002

The induced chemical and salt solution in water or admixture are originated to the corrosion process of the steeo rebar. These liquids penetrate into concrete as the accompanied by the chemical reaction and cause to attack the steel rebar in concrete. Concrete surfaces which it exposed to deicing, water and sea water is allowed to enter the chlorides in the structures. To prevent from the source of corrosion and deterioration Is subjected to put an end to corrode or reduce to contaminate on the steel rebar. As this reason the MCI 2022 products are applied to the surface of concrete and steel rebar. The concrete samples were made of to the kind of four, i.e. RF, MR, MS, and MM. Corrosion inhibitor is applied to coat on the surface of concrete after it had been cured for 28days. Specimen were immersed in a 3.5％ sodium chloride solution. Concrete specimen were tested to determine the changes of the resistance polarization, Rp, over a 22 weeks period. MCI 2022 is significantly shown the corrosion inhibition of steel rebar in 3.5% NaCl solution. In the each different concrete sample, MS and MM is seemed to be better than others. The results are proofed that MCI 2022 is promised to maintain the inhibition of corrosion with high resistance polarization of the steel rebar in concrete.

• Journal of the Korean Society of Food Science and Nutrition
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• v.31 no.1
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• pp.75-80
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• 2002

The growth inhibition by nisin-Producing lactococci against Bacillus subtilis and its application to doenjang fermentation were investigated. Lactococcus lactis subsp. lactis IFO 12007, L. lactis subsp. lactis ATCC 7962 and L. lactis subsp. lactis ATCC 11454 were used as nisin-producing lactococci. All of three strain rapidly proliferated to more than 10$^{9}$ CFU/g in steamed soybeans. Only L. lactis subsp. lactis IFO 12007 was in steamed soybean without any pH decrease. In spite of the mild decrease in pH, the growth of B. subtilis was completely inhibited; no living cells were detected in a soybean sample inoculated with 10$^{6}$ CFU/g and incubated for 24 to 72h. The L. lactis subsp. lactis IFO 12007 was applied to doenjang fermentation as a starter culture. It produced high nisin activity in steamed soybean, resulting in the complete growth inhibition of B. subtilis, which had been inoculated at the beginning of the meju fermentation, throughout the process of doenjang production. Over-acidification, which is undesirable for doenjang quality, was successfully prevented simply by adding salt which killed the salt-intolerant L. lactis subsp. lactis IFO 12007. Furthermore, the nisin activity in doenjang disappeared with aging.

• Korean Journal of Medicinal Crop Science
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• v.6 no.4
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• pp.245-250
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• 1998

This research was carried out to investigate the effective methods of browning inhibition on Paeonia lactiflra Pall during hot air dehydratin. After drying for 36 hrs without pretreatment and with briquet fumigation moisture contents of Paeonia lactiflora Pall. was 16.0% and 16.2%, respectively, while with acidic solution, sulfite salt solution and blanching it was lower of 13.5, 12.9 and 14.8%, respectively. Using freeze drying moisture content was highest of 18.8%. The Hunter values of dried Paeonia lactiflora Pall., L, a, band ${\triangle} E$ showed that non-treatment had the most browning with 61.60, 1.89, 10.20 and 39.78, respectively, while briquet fumigation and sulfite salt solution were excellent in reducing browning. During freeze drying browning didn't occur. Paeoniflorin content was 2.41 and 2.51 %, respectively, in briquet fumigation and sulfite salt solution and was the highest (2.70%) in freeze drying. The content of $SO_2$, was 0.63% both in briquet fumigation and sulfite salts. It was 0.15% and 0.17% higher than nontreatment and freeze drying. The most effective pretreatment to inhibit browning of Paeonia lactiflora Pall. was soaking in sulfite salt solution $(0.5% NaHSO_4-0.5% Na_2S_2O_3)$ considering many things such as manpower, economical efficiency, drying time, commodity, etc. but safety should be evaluated to treat sulfite salts solution on peony roots.