• Journal of Environmental Health Sciences
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• v.35 no.4
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• pp.259-268
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• 2009

This study was carried out to investigate the protective effect of Red Ginseng Saponins on 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induced toxicities in guinea pigs ($200{\pm}10$ g). Normal control (NC) group guinea pigs ($200{\pm}10$ g) received vehicle and saline, while the TCDD-treated (TT) group was given water-extract (WE), saponin fraction (SF) and non-saponin fraction (NSF). Korean red ginseng fractions were administered from 1 week before TCDD-exposure for 4 weeks. Body weight loss and deteriorated clinical parameters related to sugar metabolism and liver function such as lipase and AST, respectively, these were significantly reduced by both saponin and non-saponin fractions. However, increase of lipase was attenuated by the saponin fraction in a dose-dependent manner. Only AST was affected by the saponin fraction. The results suggest that saponins are active substances in the Korean red ginseng water extract against TCDD induced toxicities in Guinea pigs.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.5
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• pp.556-562
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• 2010

The objective of the present study was to compare feed and water intakes, growth performance and carcasscharacteristics of indigenous lamb fed diets containing various levels of halophyte Sporobolus grass hay. Forty male and female lambs were randomly and equally allotted with 5 lambs of each sex per treatment to four dietary treatment groups, which were initially formulated to have 100, 70, 30 or 0.0% Sporobolus grass hay, as a source of forage replacement for conventional Rhodes grass commonly used in the region. The lambs receiving 0.0% Sporobolus grass hay (100% Rhodes grass hay) served as the control. Feed and water were offered ad libitum. Male lambs were slaughtered at the end of the feeding trials. The average daily feed intake was significantly (p<0.05) higher for the animals fed different levels of Sporobolus grass hay than for the control animals. Feed conversion ratio (FCR), i.e., kg feed/kg BW, was similar in all treatment groups. Although lambs fed the diet with 70% Sporobolus grass hay had heavier carcass weights, the differences were not significant. In conclusion, growth performance or carcass characteristics of fattening indigenous lambs were not influenced by the inclusion of different levels of Sporobolus grass hay in the diet. Because of this, Sporobolus grass hay represents an alternative forage resource for sustaining small ruminant production in the saline coastal and subcoastal areas of the world.

• Biomedical Science Letters
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• v.6 no.2
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• pp.151-157
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• 2000

We investigated anti-diabetic effect of the crude extracts and lectin purified from the leaves of Viscum album collected in Mt. Duk Yu. The induction of diabetes mellitus was confirmed by the presence of statistically significant greater serum glucose levels in strptozotocin-treated rats compared with the untreated non-diabetic group. There are no significant differences in the serum glucose levels compared extracts and purified lectin to tap water in the non-diabetic group after administration through the oral cavity in 29 day. But for streptozotocin-induced diabetic rats the serum glucose level in extracts after administration through the oral cavity was strikely decreased to 36% than tap water in 29 day. Significantly lower glucose level was obtained at 2 hr and 4 hr after administration of purified lectin(0.4 mg/kg) through the peritoneal cavity. These results provide an evidence that Viscum album lectin has an andti-diabetic effect pharmacologically.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.464-464
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• 2011

새만금지구 간척사업은 지난 1990년대 초반 이래로 국책사업으로 수행되어 왔다. 그러나, 하류에 조성될 새만금호의 수질에 대한 일반의 우려가 높아 배수갑문을 개방하여 해수 유통을 허용하고 있고, 원래 목적인 담수호 조성이 지체되고 있다. 농업비점오염부하가 담수호의 주요 오염원의 하나로 인식되고 있고, 담수호 수질 개선을 위해서는 농업비점 저감대책이 강구되어야 한다. 본 연구의 목적은 저염도 새만금 간척지 밭을 대상으로 비종에 따른 비점오염 배출부하량을 모니터링하고 이를 정량적 평가를 하는 데 있다. 계화방조제 전면의 간석지에 간척농지 시험포장을 조성하였다. 비종으로 축분퇴비와 화학비료를 적용하고, 무시비 대조구와 비교하여 동계 청보리, 하계에 콩과 수수 작물 재배 시험을 수행하였다. 시험포장의 수문, 수질, 토양, 지하수 모니터링을 통하여 간척지 밭으로부터 오염물질 배출기작을 규명하고 비점부하를 정량적으로 산정하였다. 본 연구 결과는 염도가 높은 간척농지에서 밭작물 재배에 따른 비점부하 배출기작에 대한 이해를 증진하고, 나아가 농업비점오염 저감을 위한 영농개선 기법 개발에 중요한 기초자료를 제공할 것으로 판단된다.

• The Journal of Korean Medicine
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• v.28 no.4
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• pp.18-26
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• 2007

Objective : To study the effect of the Insamyangyoung-tang(ISYT) extract on the skin barrier function, the skin pH, skin humidity and transepidermal water loss(TEWL) were measured and histological changes were observed in DNCB(2,4-dinitrochloro-benzen)-induced contact dermatitis(CD) hairless mice. Methods : The male hairless mice were divided into three groups. Each group consisted of 15 mice. The normal group which had acetone- olive oil applied. The control group which had intentionally induced CD by DNCB and it was fed normal saline orally. The ISYT group which had intentionally induced CD by DNCB and it was fed ISYT extract orally for 7 days. The three groups were checked 24h, 48h and 72h later after inducing CD, and the skin pH, skin humidity and TEWL were observed. Tissue samples were taken, and damage to the epithelial cell was observed. Statistical analysis was performed by using one way-ANOVA: significance was set at p values less than 5% (p<0.05). Results : ISYTextract efficiently maintained the pH balance, it kept the skin humidity at a normal level, and it inhibited TEWL of the DNCB-induced CD hairless mouse. The damage to the epithelium was decreased and the regeneration power of the skin was increased in the ISYT group. Conclusion : Insamyangyoung-tang has a good effect on the skin barrier function of DNCB induced contact dermatitis hairless mice.

• The Journal of Pediatrics of Korean Medicine
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• v.25 no.1
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• pp.40-48
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• 2011

Objectives: The purpose of this study is to evaluate the effect of Gonjadaesungchimjoongbang on spatial learning abilities and memories in ischemic brain injury. Methods: Rats were separated into three groups; (1) Normal, (2) Saline medication after ischemic brain injuries (control), (3) Gonjadaesungchimjoongbang medication after ischemic brain injuries (experiment). Ischemic brain injuries was induced by MCA occlusion and reperfusion. Morris water maze test was conducted for spatial learning and memory tests. Then, the change of BDNF in the hippocampus($7^{th}$, $14^{th}$ day) was examined by immunohistoche- mistry. Results: In Morris water maze test, spatial learning abilities and memory functioning were considerably increased in the experiment group as oppose to control group on $7^{th}$ and $14^{th}$ day(p<0.01). Moreover, immunohistochemistric response of BDNF in the hippocampus indicated that the more increased immune reaction was found in the experiment group as oppose to the control group on $7^{th}$ and $14^{th}$ day. Conclusions: Gonjadaesungchimjoongbang can improve the learning abilities and memories in ischemic brain injury.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.874-878
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• 2007

최근 들어 하구의 이용도가 높아져 감에 따라 용수 취수, 염해 방지공, 하도 계획, 수질 개선 등의 문제와 관련하여 하도 내로 침입하는 염수쐐기를 적절히 제어해야 될 필요성이 대두되고 있다. 이를 위해 염수쐐기의 형태와 거동특성을 정확하게 예측하고 내부유동 구조를 구명하는 것이 필요하다. 염수쐐기의 수리학적 특성에 관한 국내외 연구는 미흡한 실정이다. 국내에서는 하구에서의 유동장 해석을 위한 연구와 염수침입 현상과 반대로 담수 유출이 해양환경에 미치는 영향에 관한 해양공학적 연구가 주로 수행되었다. 국외에서는 1950년대 초반에 하구에서의 염도 혼합양상과 확산계수의 결정 및 수학적 모형에서 각 항들의 상대적 중요성 평가와 같은 기초적인 연구가 수행되었으며, 1970년대에 컴퓨터의 급속한 발전에 힘입어 다양한 수치적 기법이 개발되어 폭이 좁고 성층화된 하구에서의 수치계산이 수행되었다. 본 연구에서는 정상 염수쐐기의 형태 및 거동특성을 파악하기 위하여 수리실험을 수행하였다. 실험은 염수수조, 담수유입부, 수로부로 구성된 실험수로에서 수행되었으며, 염수와 담수간의 밀도차에 근거하여 실험 조건을 설정하였다. 실험을 통하여 밀도차와 담수유입량에 따라 염수쐐기의 형태 및 거동특성이 지배됨을 관찰할 수 있었다.

• Membrane Journal
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• v.27 no.2
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• pp.109-120
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• 2017

The reverse electrodialysis (RED) is an energy generation system to convert chemical potential of saline water directly into electric energy via the combination of current derived from a redox couple electrolyte and ionic potential obtained when cation ($Na^+$) and anion ($Cl^-$) pass through cation exchange membrane (CEM) and anion exchange membrane (AEM) into fresh water, respectively. Ion exchange membrane, a key element of RED system, should satisfy requirements such as 1) low swelling behavior, 2) a certain level of ion exchange capacity, 3) high ion conductivity, and 4) high perm-selectivity to achieve high power density. In this paper, research trends and prospects of ionomer materials and ion exchange membranes are dealt with.

• Textile Coloration and Finishing
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• v.21 no.4
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• pp.39-45
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• 2009

PVA films were crosslinked with dimethylol dihydroxy ethylene urea (DMDHEU) and three polycarboxylic acids of butanetetracarboxylic acid (BTCA), citric acid and malic acid Different factors influencing the crosslinking treatment with BTCA were investigated including BTCA and sodium hypophosphite (SHP) concentration, curing temperature and time. The cured films was extracted with boiling water and gel fraction was calculated based on weight change of the PVA films. The gel fraction of PVA films increased with increasing curing temperature and time. And the resistance to water and thermal stability of the crosslinked PVA films improved with the BTCA crosslinking treatment. While crosslinking with citric acid gave the highest gel fraction among the crosslinkers, crosslinking with malic acid showed the highest absorbancy in 0.9% saline solution, which was attributed to lower crosslink density and high number-average molecular weight between crosslinks. The superabsorbent PVA films could be prepared by adjusting the crosslinking condition of PVA with polycarboxilic acids.

• The Korean Journal of Pharmacology
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• v.14 no.1_2
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• pp.25-31
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• 1978

It has recently been reported that prostaglandin $(PG)F_{2\alpha}$ produces diruesis and natriuresis when given directly into a lateral ventricle of the brain in rabbits (Kook et al). In this study attempts were made to elucidate the mechanism of the natriuresis utilizing dogs. In mongrel dogs of both sexes weighing 9-l2kg, a lateral ventricle of the cerebrum was cannulated and the agent was delivered in less than 0.2ml of 0.9% saline. $PGF_{2\alpha}$, $100\;{\mu}g$, ivt, elicited mild diuresis, while glomerular filtration rate and systemic blood pressure remained unchanged. In 8 chloralso-anesthetized, hydrated dogs undergoing water diuresis, ivt $PGF_{2\alpha}$ produced antidiuresis concomitant with marked natriuresis, which resembles the action of large doses of Arginine vasopressin in doses of 0.3-1.5mu/kg/min produced marked natriuresis. In 9 experiments, $PGF_{2\alpha}$ was given intraventricularly during the maximal diuresis induced by ADH. The kidney responded with significant natriuresis though less marked and transient than during water diuresis. It is thus concluded that beside ADH still other natriuretic factor(s) may be involved in the natriuresis induced by ivt $PGF_{2\alpha}$ in the dog.