• Journal of Advanced Marine Engineering and Technology
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• v.40 no.6
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• pp.484-492
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• 2016

The turbine is an important component and has a significant impact on the thermodynamic efficiency of the organic Rankine cycle. A precise preliminary design is essential to developing efficient turbines. In addition, performance analysis and structural analysis are needed to evaluate the performance and structural safety. However, there are only a few exclusive studies on the development process of the radial inflow turbines for the organic Rankine cycle (ORC). In this study, a preliminary design of the ORC radial inflow turbine was performed. Subsequently, the performance and structural analysis were also carried out. The RTDM, which was developed as an in-house code, was used in the preliminary design process. The results of the performance analysis were found to be in good agreement with target performances. Structural analysis of the designed turbine was also carried out in order to determine whether the material selection for this study is suitable for the flow conditions of the designed turbine, and it was found that the selected aluminum alloy is suitable for the designed turbine. However, the reliability of the preliminary design algorithms and numerical methods should be strictly verified by an actual experimental test.

• Korean Journal of Microbiology
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• v.43 no.2
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• pp.91-99
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• 2007

For the detection of Human Immunodeficiency Virus (HIV), multiple and ultra-rapid real-time PCR methods were developed. The target DNA sequences were deduced from HIV-1 specific 495bp partial env gene (gi_1184090) and from HIV-2 specific 294 bp partial env gene (gi_1332355), and were synthesized by using PCR-based gene synthesis on the reason of safety. Ultra-rapid real-time PCR was performed by $Genspector^{TM}$ using microchip-based, $1\;{\mu}l$ of reaction volume with extremely short time in each 3 step in PCR. The detection including DNA-amplification and melting temperature analysis was completed inner 15 minutes. The HIV-1 specific 117 bp-long and HIV-2 specific 119 bp-long PCR products were successfully amplified from minimum of template,2.3 molecules of each env gene. This kind of real-time PCR was designated as ultra-rapid real-time PCR in this study and it could be applied not only an alternative detection method against HIV, but also other pathogens using PCR-based detection.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.12
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• pp.778-784
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• 2017

In this paper, we propose wired and wireless distributed control systems designed to improve the freight logistics efficiency and verify wired distributed control systems. The verification condition required that 50 cargo vehicles be connected and operated to travel 21 km from Busan Sinhang station to Jinlye Station at an average speed of about 100km/h. The verification results show that the traction output and braking output of the control and controlled cars are dispersed by the wired distributed control system. The application is expected to more than double the efficiency of the logistics compared to the existing freight transportation system. However, in the case of the wired distributed control system, cable installation and maintenance are difficult, and it is impossible to change the combination of freight vehicles. Through the verification of the wired distributed control system, the applicability of distributed control systems to freight vehicles in Korea was confirmed and the system was further developed to produce a wireless distributed control system. In order to apply the wireless distributed control system, a propagation environment analysis for the ISM band was performed in the testbed and, as a result, it was confirmed that Wifi technology using the ISM band could be utilized. In order to use the WDP (Wireless Distributed Power) devices newly installed in the target vehicles, the transmission / reception control signals associated with the propulsion / braking / total control devices are defined. In the case of wireless distributed control systems, the convenience of their application and operation is guaranteed, but reliability and emergency safety measures should because of the dependence of the control of the vehicle on radio signals.

• Journal of Astronomy and Space Sciences
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• v.29 no.4
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• pp.381-387
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• 2012

The planetary exploration rover executes various missions after moving to the target point in an unknown environment in the shortest distance. Such missions include the researches for geological and climatic conditions as well as the existence of water or living creatures. If there is any obstacle on the way, it is detected by such sensors as ultrasonic sensor, infrared light sensor, stereo vision, and laser ranger finder. After the obtained data is transferred to the main controller of the rover, decisions can be made to either overcome or avoid the obstacle on the way based on the operating algorithm of the rover. All the planetary exploration rovers which have been developed until now receive the information of the height or width of the obstacle from such sensors before analyzing it in order to find out whether it is possible to overcome the obstacle or not. If it is decided to be better to overcome the obstacle in terms of the operating safety and the electric consumption of the rover, it is generally made to overcome it. Therefore, for the purpose of carrying out the planetary exploration task, it is necessary to design the proper suspension system of the rover which enables it to safely overcome any obstacle on the way on the surface in any unknown environment. This study focuses on the design of the new double 4-bar linkage type of suspension system applied to the Korea Aerospace Research Institute rover (a tentatively name) that is currently in the process of development by our institute in order to develop the planetary exploration rover which absolutely requires the capacity of overcoming any obstacle. Throughout this study, the negative moment which harms the capacity of the rover for overcoming an obstacle was induced through the dynamical modeling process for the rocker-bogie applied to the Mars exploration rover of the US and the improved version of rocker-bogie as well as the suggested double 4-bar linkage type of suspension system. Also, based on the height of the obstacle, a simulation was carried out for the negative moment of the suspension system before the excellence of the suspension system suggested through the comparison of responding characteristics was proved.

• Ecology and Resilient Infrastructure
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• v.3 no.4
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• pp.285-293
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• 2016

This study conducted the evaluations of stable channel and physical disturbance improvement for optimal construction of river structures by focusing on Wonju River. A stable slope was analyzed sectionally for stable channel design, and in order to satisfy the stable slope, river structure improvement scenarios were deduced. Accordingly, through physical disturbance improvement evaluation for each scenario, the study extracted the optimal scenario for stable channel design and physical disturbance improvements. The changes in physical habitat were analyzed when river structure improvements were made for stable channel design and physical disturbance improvement. Zacco koreanus, an indicator fish of the soundness of the aquatic ecosystem, was selected as a restoration target species by investigating the community characteristics of fish fauna and river environments in the Wonju River. The habitat suitability was investigated by the PHABSIM model with the habitat suitability index of Zacco koreanus. The results of the prediction evaluation showed a slight decrease in habitat suitability and weighted usable area. However, it was not influenced by the improvements in the river structure. The study suggested river structure arrangement methods that can improve physical soundness and safety of Wonju River, and confirmed that there were no effects to the changes in the physical habitat.

• Toxicological Research
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• v.22 no.4
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• pp.445-452
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• 2006

Aralia elata, a common medicinal and culinary herb, has beer consumed for centuries without any reported adverse effects. However, due to its limited safety information, we decided to investigate the repeated-dose toxicity of ethanolic extract of Aralia elata. The test was administered once daily by the gavage to male and female rats at doses of 0, 250, 500 and 1,000 mg/kg/day for four weeks. Throughout the study, no treatment-related deaths or clinical signs were observed. Also, no apparent changes were detected in ophthalmoscopy, urinalysis, serum biochemistry, hematology and gross necropsy. The test result showed a significant decrease in body and heart weight of males treated with 250 mg/kg of extract of Aralia elata compared to normal control, a significant increase in relative brain weight and adrenal weight in females treated with 250 mg/kg of extract compared to normal control. However, all these changes were not considered toxicologically important due to irrelevant dose-response relationship to gross and microscopic findings. Histopathologically, abnormal changes were not observed in any target organs. On the basis of these results, the NOAEL of extract of Aralia elata was estimated to be more than 1,000 mg/kg/day under the tested conditions.

• Biomolecules & Therapeutics
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• v.16 no.1
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• pp.54-60
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• 2008

Dyslipidemia is the multiple lipid metabolic disorders which is one of the high risk factors for the atherosclerotic diseases. It increases the morbidity and mortality and therefore, must be treated with antilipidemic agents. HMG-Co A reductase inhibitors (statins), one of many antidyslipidemic agents, have shown to be significant improvement from the various cholesterol levels. Especially, data from many comparative trials suggest that rosuvastatin is more effective than atorvastatin among many other statins. The aims of this study were to evaluate the efficacy and safety between rosuvastatin and atorvastatin in the treatment of Korean patients with dyslipidemia. Currently the Korean Society of Lipidology and Atherosclerosis based on the Korean health screening data suggests that Korean patients with dyslipidemia should be treated by the target cholesterol levels according to the Adult Treatment Panel III guidelines of the US National Cholesterol Education Program (NCEP-ATP III). We reviewed retrospectively all medical histories of the total 392 dyslipidemic patients with atorvastatin or rosuvastatin from June 1st, 2004 to August 31st, 2006 in Chungbuk National University Medical Center. Patients were classified as total 4 groups by the NCEP-ATP III Guidelines. The numbers of enrolled patients were each 5 mg atorvastatin (n=34), 10 mg atorvastatin (n=148), 5 mg rosuvastatin (n=94) and 10 mg rosuvastatin (n=82). In comparison between groups, rosuvastatin groups in the lowering LDL-C had better efficacies, and the results were each 22% (5 mg atorvastatin), 33.3% (10 mg atorvastatin), 35% (5 mg rosuvastatin) and 41.3% (10 mg rosuvastatin) with the dose relationship (P=0.000). Rosuvastatin groups also have shown to be more significantly reducing Total Cholesterol levels compared to atorvastatin groups with the no dose relationship (P=0.000). In the lowering of non-HDL cholesteroles, rosuvastatin groups showed significantly better efficacies than atorvastatin with the dose-relationship (P=0.000). Each medication groups did not demonstrate the differences in the changing of HDL cholesterol and triglyceride levels (P=0.096, 0.309, respectively). In conclusion, rosuvastatin was better efficacious than atrovastatin in reducing LDL-C Total Chol, and Tg. Therefore, rosuvastatin is a good antilipidemic agents for Korean patients with dyslipidemia and it can use to minimize the morbidity and mortality related to the cardiovascular diseases in Korean.

• Fire Science and Engineering
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• v.31 no.2
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• pp.119-126
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• 2017

This study examined the soundness, vibration, and size of ambulances currently used in Korea as well as the comfort and convenience of ambulancesin Korea. The target vehicles were measured and investigated using the currently used freight type, van type, and Benz ambulance. Currently, the ambulance standards in Korea have only formal production standards, and there is no regulation on safety for ambulances, space regulation for first aid, comfort, and convenience. Therefore, comparative experiments on the comfort and convenience were measured using noise and vibration measurement experiments, and research was conducted on the size and interior rearrangement of ambulances to investigate the areas that can improve the comfort and convenience. The noise measurementsshowed that the noise was large in the order of the van type, Benz type, and freight type. In the case of a speed of 40 km/h or more, the noise measurement result was 60 to 70 dB or more. In the case of vibration, the Benz type and van type ambulance were good, and the vibration of the freight type showed the worst result, highlighting the need for improvement. Lastly, it is not possible to increase the internal size of the structure of domestic ambulance. On the other hand, it is important that through ambulance relocation and the position of first aid personnel, it will be possible to use it more comfortably and conveniently.

• Journal of the Society of Disaster Information
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• v.8 no.3
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• pp.287-296
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• 2012

This study is analysis of the existing domestic terrorism factors and suggest countermeasures for political leadership that can occur to the precautionary terror occasion of the presidential election approached 100 days in the future. Political terror caused mainly achieved peak of Ideology or social conflict by Politically alienated class. Common cause is most likely to occur when the party or the government want to attack a target or can not stand disadvantaged and lose that I suppert the party or the government. 21st century political terror is occurred with Misfits of complaints expressed or social conflict more frequency than attack used random people, new weqpon and bomb. It is interpreted that issued as a drastic measure from individual complaint because of increased polarization of wealth by separate into group and fallen law and order but also we are not familiar with the political compromises. Personal safety escort mission is essential condition of political activity that Absolute personal protection and to come up with a large number of voters for best result. Thus security guard ought to professional security activity depend on gathered situation, location and regional feature for perfect protection service.

• Journal of the Korea institute for structural maintenance and inspection
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• v.16 no.5
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• pp.148-160
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• 2012

This study proposed more reasonable prediction models on compressive strength and carbonation of concrete structure and developed a more effective tunnel safety diagnosis and maintenance method through field application of the proposed prediction models. For this study, the Seoul Metro's Line 1 through Line 4 were selected as target structures because they were built more than 30 years ago and have accumulated numerous diagnosis and maintenance data for about 15 years. As a result of the analysis of compressive strength and carbonation, we were able to draw prediction models with accuracy of more than 80% and confirmed the prediction model's reliability by comparing it with the existing models. We've also confirmed field suitability of the prediction models by applying field, the average error of an estimate on compressive strength and carbonation depth was about 20%, which showed an accuracy of more than 80%. We developed a more effective maintenance method using durability prediction Map before field inspection. With the durability prediction Map, diagnostic engineers and structure managers can easily detect the vulnerable points, which might have failed to reach the standard of designed strength or have a high probability of corrosion due to carbonation, therefore, it is expected to make it possible for them to diagnose and maintain tunnels more effectively and efficiently.