• Title/Summary/Keyword: safety risk factor

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Clinical study of Bangpoongtongsungsan on body weight change in subjects with obesity (방풍통성산이 비만인에 미치는 영향에 대한 임상적 연구)

  • Shin, Dae-Hee;Cho, Guk-Hyun;Lee, Hyuck;Moon, Mi-Kyung;Kang, Dae-Gill;Yun, Young-Gab;Park, Do-Shim;Juhng, Seon-Kwan;Lee, Ho-Sub
    • Herbal Formula Science
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    • v.16 no.2
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    • pp.133-144
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    • 2008
  • Recently, people are becoming fatter in most parts of the world. Obesity is regarded as an important risk factor to adversely affect the health of humans, associated with hypertension, hyperlipidemia, diabetes, and cardiovascular diseases. In the present study, therefore, we tested the short time efficiency and safety of Bangpoongtongsungsan as a drug to decrease body weight in subjects with obesity. A total 48 volunteers (24 man, 24 woman) with body mass index (BMI : weight in kg divided by square of height in meters) of $23㎏/m^2$ participated in clinical study for 12 weeks, from 2008, March 01 to 2008, Jun 30. The subjects was received a dietary supplement of 12 pieces hard capsules per day (4 pieces in one, 3 times in a day) during the clinical study. At the end of clinical study, body weight of subjects was significantly decreased from $72.21{\pm}11.44\;kg$ to $70.53{\pm}11.67\;kg$ (p<0.05). Waist circumferences of subjects were reduced $91.58{\pm}6.43\;cm$ to $85.25{\pm}7.70\;cm$ (p<0.05). Also, a BMI of subjects was significantly decreased $26.07{\pm}2.35\;kg/m^2$ to $25.63{\pm}2.63\;kg/m^2$ (p<0.05). Particularly, a decrease in body weight, waist circumferences, and BMI was more significant in woman than man. But, other biochemical levels including lipid and glucose in plasma had no changes at the end of clinical study. In conclusion, administration of Bangpoongtongsungsan in subjects with high body weight fat could inhibit obesity associated with a decrease in body weight, waist circumferences, and BMI.

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A Study on Fire Explosion Characteristics via Physico-chemical Analysis of Petroleum Residues (석유 부산물의 물리화학적 분석을 통한 화재폭발 특성연구)

  • Kim, Hyeonggi;Lee, Young-Seak
    • Applied Chemistry for Engineering
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    • v.30 no.5
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    • pp.556-561
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    • 2019
  • In this study, the physical and chemical analyses of petroleum residues (pyrolized fuel oil, PFO) were conducted and major components were selected to investigate their fire and explosion characteristics. Major component distribution areas of the PFO were identified via the GC-SIMDIS and MALDI-TOF analyses. In addition, the qualitative analysis of major component distribution areas was performed by GC-MS analysis. Major components of pyrolysis residue were selected based on the results of various analyses such as EA, SARA and TGA. As a result, benzene, toluene and xylene were selected as major components. Finally, the process hazard analysis software tool (PHAST) analysis was performed to investigate the range of maximum damage effect in case of fire and explosion. Toluene presented the highest risk due to the radiation effect of $227kW/m^2$ and 118 m in the case of jet fire. Xylene and benzene showed the maximum radiant heat values of 114 and $151kW/m^2$, respectively. It was also confirmed from the analysis of pasquill stability and wind speed that the radiant heat increased up to 55% according to wind speed in benzene, which was considered to be a main factor increasing the influence range.

Factors Influencing Driving ability and Its Measurements in Older Driver: A Systematic Review (고령자의 운전능력 영향요인 및 측정도구에 대한 체계적 문헌고찰)

  • Woo, Ye-Shin;Shin, Ga-In;Park, Sang-Mi;Park, Hae Yean
    • 한국노년학
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    • v.38 no.1
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    • pp.225-241
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    • 2018
  • Self-driving is meaningful activity for older persons because it enlarges the range of activity and provides opportunities for social participation. Driving is a complex activity that requires integration of physical, cognitive and sensory functions and is influenced by human and psychological factors. Age related functional deterioration affects the driving ability of older drivers. The purpose of this study is to investigate the factors affecting the risk of accidents and driving cessation of elderly drivers through systematic literature review. MEDLINE, EMBASE, Cochrane Library, KoreaMed, Pubmed were used for searching articles published from 2007 to 2017. 'aged', 'aging', 'automobile driving', 'age factors' were used as search terms and 18 articles were finally selected for analysis among 1,458 articles. In result of the study, the most significant effect showed in the physical domain, the driving habit and the performance function. The most frequent used tools evaluated driving habit and the cognitive function. In demographic characteristics, there was a correlation with the driving discontinue according to sex and age. This study emphasizes the necessity of preparing measures for safety driving with elderly. In addition, it suggests the necessity of systematically services such as individual education programs based on various driving cessation related factors of the elderly.

The Effect of Communication Distance and Number of Peripheral on Data Error Rate When Transmitting Medical Data Based on Bluetooth Low Energy (저 전력 블루투스 기반으로 의료데이터 전송 시 통신 거리와 연동 장치의 수가 데이터 손실률에 미치는 영향)

  • Park, Young-Sang;Son, ByeongJin;Son, Jaebum;Lee, Hoyul;Jeong, Yoosoo;Song, Chanho;Jung, Euisung
    • Journal of Biomedical Engineering Research
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    • v.42 no.6
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    • pp.259-267
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    • 2021
  • Recently, the market for personal health care and medical devices based on Bluetooth Low Energy(BLE) has grown rapidly. BLE is being used in various medical data communication devices based on low power consumption and universal compatibility. However, since data errors occurring in the transmission of medical data can lead to medical accidents, it is necessary to analyze the causes of errors and study methods to reduce data error. In this paper, the minimum communication speed to be used in medical devices was set to at least 800 byte/sec based on the wireless electrocardiography regulations of the Ministry of Food and Drug Safety. And the data loss rate was tested when data was transmitted at a speed higher than 800 byte/sec. The factors that cause communication data error were classified, and the relationship between each factor and the data error rate was analyzed through experiments. When there were two or more activated peripherals connected to the central, data error occurred due to channel hopping and bottleneck, and the data error rate increased in proportion to the communication distance and the number of activated peripherals. Through this experiment, when the BLE is used in a medical device that intermittently transmits biosignal data, the risk of a medical accident is predicted to be low if the number of peripherals is 3 or less. But, it was determined that BLE would not be suitable for the development of a biosignal measuring device that must be continuously transmitted in real time, such as an electrocardiogram.

A Study on the Method for Managing Hazard Factors to Support Operation of Automated Driving Vehicles on Road Infrastructure (자율주행시스템 운행지원을 위한 도로 인프라 측면의 위험 요소 관리 방안)

  • Kim, Kyuok;Choi, Jung Min;Cho, Sun A
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.2
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    • pp.62-73
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    • 2022
  • As the competition among the autonomous vehicle (AV, here after) developers are getting fierce, Korean government has been supporting developers by deregulating safety standards and providing financial subsidies. Recently, some OEMs announced their plans to market Lv3 and Lv4 automated driving systems. However, these market changes raised concern among public road management sectors for monitoring road conditions and alleviating hazardous conditions for AVs and human drivers. In this regards, the authors proposed a methodology for monitoring road infrastructure to identify hazardous factors for AVs and categorizing the hazards based on their level of impact. To evaluate the degrees of the harm on AVs, the authors suggested a methodology for managing road hazard factors based on vehicle performance features including vehicle body, sensors, and algorithms. Furthermore, they proposed a method providing AVs and road management authorities with potential risk information on road by delivering them on the monitoring map with node and link structure.

Major Factors Influencing Landslide Occurrence along a Forest Road Determined Using Structural Equation Model Analysis and Logistic Regression Analysis (구조방정식과 로지스틱 회귀분석을 이용한 임도비탈면 산사태의 주요 영향인자 선정)

  • Kim, Hyeong-Sin;Moon, Seong-Woo;Seo, Yong-Seok
    • The Journal of Engineering Geology
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    • v.32 no.4
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    • pp.585-596
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    • 2022
  • This study determined major factors influencing landslide occurrence along a forest road near Sangsan village, Sancheok-myeon, Chungju-si, Chungcheongbuk-do, South Korea. Within a 2 km radius of the study area, landslides occur intensively during periods of heavy rainfall (August 2020). This makes study of the area advantageous, as it allows examination of the influence of only geological and tomographic factors while excluding the effects of rainfall and vegetation. Data for 82 locations (37 experiencing landslides and 45 not) were obtained from geological surveys, laboratory tests, and geo-spatial analysis. After some data preprocessing (e.g., error filtering, minimum-maximum normalization, and multicollinearity), structural equation model (SEM) and logistic regression (LR) analyses were conducted. These showed the regolith thickness, porosity, and saturated unit weight to be the factors most influential of landslide risk in the study area. The sums of the influence magnitudes of these factors are 71% in SEM and 83% in LR.

CycleGAN Based Translation Method between Asphalt and Concrete Crack Images for Data Augmentation (데이터 증강을 위한 순환 생성적 적대 신경망 기반의 아스팔트와 콘크리트 균열 영상 간의 변환 기법)

  • Shim, Seungbo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.5
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    • pp.171-182
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    • 2022
  • The safe use of a structure requires it to be maintained in an undamaged state. Thus, a typical factor that determines the safety of a structure is a crack in it. In addition, cracks are caused by various reasons, damage the structure in various ways, and exist in different shapes. Making matters worse, if these cracks are unattended, the risk of structural failure increases and proceeds to a catastrophe. Hence, recently, methods of checking structural damage using deep learning and computer vision technology have been introduced. These methods usually have the premise that there should be a large amount of training image data. However, the amount of training image data is always insufficient. Particularly, this insufficiency negatively affects the performance of deep learning crack detection algorithms. Hence, in this study, a method of augmenting crack image data based on the image translation technique was developed. In particular, this method obtained the crack image data for training a deep learning neural network model by transforming a specific case of a asphalt crack image into a concrete crack image or vice versa . Eventually, this method expected that a robust crack detection algorithm could be developed by increasing the diversity of its training data.

From Radon and Thoron Measurements, Inhalation Dose Assessment to National Regulation and Radon Action Plan in Cameroon

  • Saidou;Shinji Tokonami;Masahiro Hosoda;Augustin Simo;Joseph Victor Hell;Olga German;Esmel Gislere Oscar Meless
    • Journal of Radiation Protection and Research
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    • v.47 no.4
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    • pp.237-245
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    • 2022
  • Background: The current study reports measurements of activity concentrations of radon (220Rn) and thoron (220Rn) in dwellings, followed by inhalation dose assessment of the public, and then by the development of regulation and the national radon action plan (NRAP) in Cameroon. Materials and Methods: Radon, thoron, and thoron progeny measurements were carried out from 2014 to 2017 using radon-thoron discriminative detectors (commercially RADUET) in 450 dwellings and thoron progeny monitors in 350 dwellings. From 2019 to 2020, radon track detectors (commercially RADTRAK) were deployed in 1,400 dwellings. It was found that activity concentrations of radon range in 1,850 houses from 10 to 2,620 Bq/㎥ with a geometric mean of 76 Bq/㎥. Results and Discussion: Activity concentrations of thoron range from 20 to 700 Bq/㎥ with a geometric mean of 107 Bq/㎥. Thoron equilibrium factor ranges from 0.01 to 0.6, with an arithmetic mean of 0.09 that is higher than the default value of 0.02 given by UNSCEAR. On average, 49%, 9%, and 2% of all surveyed houses have radon concentrations above 100, 200, and 300 Bq/㎥, respectively. The average contribution of thoron to the inhalation dose due to radon and thoron exposure is about 40%. Thus, thoron cannot be neglected in dose assessment to avoid biased results in radio-epidemiological studies. Only radon was considered in the drafted regulation and in the NRAP adopted in October 2020. Reference levels of 300 Bq/㎥ and 1,000 Bq/㎥ were recommended for dwellings and workplaces. Conclusion: Priority actions for the coming years include the following: radon risk mapping, promotion of a protection policy against radon in buildings, integration of the radon prevention and mitigation into the training of construction specialists, mitigation of dwellings and workplaces with high radon levels, increased public awareness of the health risks associated with radon, and development of programs on the scientific and technical aspects.

Tissue Adequacy and Safety of Percutaneous Transthoracic Needle Biopsy for Molecular Analysis in Non-Small Cell Lung Cancer: A Systematic Review and Meta-analysis

  • Bo Da Nam;Soon Ho Yoon;Hyunsook Hong;Jung Hwa Hwang;Jin Mo Goo;Suyeon Park
    • Korean Journal of Radiology
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    • v.22 no.12
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    • pp.2082-2093
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    • 2021
  • Objective: We conducted a systematic review and meta-analysis of the tissue adequacy and complication rates of percutaneous transthoracic needle biopsy (PTNB) for molecular analysis in patients with non-small cell lung cancer (NSCLC). Materials and Methods: We performed a literature search of the OVID-MEDLINE and Embase databases to identify original studies on the tissue adequacy and complication rates of PTNB for molecular analysis in patients with NSCLC published between January 2005 and January 2020. Inverse variance and random-effects models were used to evaluate and acquire meta-analytic estimates of the outcomes. To explore heterogeneity across the studies, univariable and multivariable metaregression analyses were performed. Results: A total of 21 studies with 2232 biopsies (initial biopsy, 8 studies; rebiopsy after therapy, 13 studies) were included. The pooled rates of tissue adequacy and complications were 89.3% (95% confidence interval [CI]: 85.6%-92.6%; I2 = 0.81) and 17.3% (95% CI: 12.1%-23.1%; I2 = 0.89), respectively. These rates were 93.5% and 22.2% for the initial biopsies and 86.2% and 16.8% for the rebiopsies, respectively. Severe complications, including pneumothorax requiring chest tube placement and massive hemoptysis, occurred in 0.7% of the cases (95% CI: 0%-2.2%; I2 = 0.67). Multivariable meta-regression analysis showed that the tissue adequacy rate was not significantly lower in studies on rebiopsies (p = 0.058). The complication rate was significantly higher in studies that preferentially included older adults (p = 0.001). Conclusion: PTNB demonstrated an average tissue adequacy rate of 89.3% for molecular analysis in patients with NSCLC, with a complication rate of 17.3%. PTNB is a generally safe and effective diagnostic procedure for obtaining tissue samples for molecular analysis in NSCLC. Rebiopsy may be performed actively with an acceptable risk of complications if clinically required.

Exploratory Study on Enhancing Cyber Security for Busan Port Container Terminals (부산항 컨테이너 터미널 사이버 보안 강화를 위한 탐색적 연구)

  • Do-Yeon Ha;Yul-Seong Kim
    • Journal of Navigation and Port Research
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    • v.47 no.6
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    • pp.437-447
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    • 2023
  • By actively adopting technologies from the Fourth Industrial Revolution, the port industry is trending toward new types of ports, such as automated and smart ports. However, behind the development of these ports, there is an increasing risk of cyber security incidents and threats within ports and container terminals, including information leakage through cargo handling equipment and ransomware attacks leading to disruptions in terminal operations. Despite the necessity of research to enhance cyber security within ports, there is a lack of such studies in the domestic context. This study focuses on Busan Port, a representative port in South Korea that actively incorporates technology from the Fourth Industrial Revolution, in order to discover variables for improving cyber security in container terminals. The research results categorized factors for enhancing cyber security in Busan Port's container terminals into network construction and policy support, standardization of education and personnel training, and legal and regulatory factors. Subsequently, multiple regression analysis was conducted based on these factors, leading to the identification of detailed factors for securing and enhancing safety, reliability, performance, and satisfaction in Busan Port's container terminals. The significance of this study lies in providing direction for enhancing cyber security in Busan Port's container terminals and addressing the increasing incidents of cyber security attacks within ports and container terminals.