• Title/Summary/Keyword: safety limits

Search Result 892, Processing Time 0.021 seconds

Establishment of Pre-Harvest Residue Limits (PHRLs) of Insecticide Clothianidin and Fungicide Fluquinconazole on Peaches during Cultivation Period (복숭아의 재배기간 중 살충제 Clothianidin 및 살균제 Fluquinconazole의 생산단계 농약잔류허용기준의 설정)

  • Park, Jae-Hun;Lim, Jong-Sung;Yoon, Ji-Yeong;Moon, Hye-Ree;Han, Ye-Hoon;Lee, Yong-Jae;Lee, Kyu-Seung
    • Korean Journal of Environmental Agriculture
    • /
    • v.31 no.3
    • /
    • pp.271-276
    • /
    • 2012
  • BACKGROUND: It is hard to control the agricultural products exceeding MRL (maximum residue limit) before forwarding. Therefore, NAQS (National Agricultural Products Quality Management Service, South Korea) established PHRL (pre-harvest residue limit) on agricultural products during their cultivation periods. This study was performed to set the PHRLs of peach during cultivation period, and also to estimate biological half-lives for residues of clothianidin and fluquinconazole. METHODS AND RESULTS: Two groups of peach were treated under Korean GAP (Good Agricultural Practices) with application time, single and triple treatments. Sample was collected over 14days (each after 0, 2, 4, 6, 8, 10, 12, 14 days. 8times), and clothianidin and fluquinconazole were analyzed by HPLC/DAD and GC/ECD, respectively. CONCLUSION: The biological half-life of clothianidin in single treatment and triple treatment was 5.2days and 7.0days. That of fluquinconazole was also 3.9days and 4.1days, respectively. The PHRL of peach on 10days before harvest was 1.4 mg/kg in clothianidin and 1.8 mg/kg in fluquinconazole.

The Measurement and Prediction of Combustible Properties for Ethylbenzene (에틸벤젠의 연소특성치 측정 및 예측)

  • Ha, Dong-Myeong
    • Journal of Energy Engineering
    • /
    • v.23 no.4
    • /
    • pp.169-175
    • /
    • 2014
  • For the safe handling of ethylbenzene, this study was investigated the explosion limits of ethylbenzene in the reference data. And the lower flash points, upper flash points and AITs(auto-ignition temperatures) by ignition delay time were experimented. The lower flash points of ethylbenzene by using Setaflash closed-cup and Pensky-Martens closed-cup testers were experimented $20^{\circ}C$ and $22^{\circ}C$, respectively. The lower flash points ethylbenzene by using Tag and Cleveland open cup testers were experimented $25^{\circ}C$ and $28^{\circ}C$, respectively. Also, this study measured relationship between the AITs and the ignition delay times by using ASTM E659 tester for ethylbnezene. The experimental AIT of ethylbenzene was $430^{\circ}C$. The calculated LEL and UEL by using the measured lower flash point and upper flash point were 0.93 Vol.% and 7.96 Vol.%, respectively.

Influence of Taking Medicine for a Period of Time on the Liver Function and Improvement of the Developmental Disordered Children (한약 장기복용이 발달장애아동의 간기능과 건강증진에 미치는 영향)

  • Park, Jae-Hyung;Park, Jae-Hyun;Yoon, Young-Joo;Jeong, Seul-Ki;Lee, Hyun-Jung;Lim, Ja-Sung;Bahn, Geon-Ho;Moon, Jin-Soo;Paeck, Eun-Kyung
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.20 no.2
    • /
    • pp.494-497
    • /
    • 2006
  • A child with five delay, five ankylosis, five weakening needs to take herbal medicine for a long term. So safety, efficacy inspection for the long term usage of herbal medicine and mixed dose is needed because other medication or functional health foods, etc could be taken during this process. Operated liver function test before and after dosing herbal medicine to one hundred and sixty children who aided private oriental medicine located in Seoul, and measured the efficacy by comparing sleeping hours, morbidity, stamina, sanguineness, personality, digestion with the state before taking herbal medicine based on questionnaire done by the parents. Every children were under the limits, and there were no differences between boys and girls, and no notable differences according to family histories. There were positive results in efficacy inspection ordered as improvement in personality, stamina, sanguineness, decrease in morbidity, increase in appetite, digestion. No signs of disorder in liver function has been found during the dose of herbal medicine or simultaneous medicine, and shown promotion of health.

Development and Application of a Method for Rapid and Simultaneous Determination of Three β-agonists (Clenbuterol, Ractopamine, and Zilpaterol) using Liquid Chromatography-tandem Mass Spectrometry

  • Sung, In Kyung;Park, Seo Jung;Kang, Kyutae;Kim, Min Young;Cho, Seongbeom
    • Food Science of Animal Resources
    • /
    • v.35 no.1
    • /
    • pp.121-129
    • /
    • 2015
  • ${\beta}$-agonists are anabolic compounds that promote fat loss and muscle gain, and their administration to livestock may provide economic benefits by increasing growth rate and feed efficiency. For these reasons, ${\beta}$-agonists are also commonly added to livestock feed as growth promoters. This can introduce a significant risk of secondary human poisoning through intake of contaminated meat. A new method for the simultaneous determination of three ${\beta}$-agonists (clenbuterol, ractopamine, and zilpaterol) was developed in this study and applied to various meat samples. The limits of quantification, derived through a validation test following Codex guidelines, were $0.2{\mu}g/kg$ for clenbuterol and zilpaterol, and $0.4{\mu}g/kg$ for ractopamine. The average recoveries for clenbuterol, ractopamine, and zilpaterol ranged from 109.1% to 118.3%, 95.3% to 109.0%, and 94.1% to 120.0%, respectively. The recovery and coefficient of variation (CV) values fell within the acceptable range according to the Codex guidelines. This method reduced the analysis time without decreasing detection efficiency by modifying the pretreatment steps. This method could be utilized to manage the safety of imported meat products from countries where zilpaterol use is still permitted, thereby improving public health and preventing ${\beta}$-agonist poisoning due to secondary contamination.

Synthesis of polysulfone beads impregnated with Ca-sepiolite for phosphate removal

  • Hong, Seung-Hee;Lee, Chang-Gu;Jeong, Sanghyun;Park, Seong-Jik
    • Membrane and Water Treatment
    • /
    • v.11 no.1
    • /
    • pp.69-77
    • /
    • 2020
  • Former studies revealed that sepiolite thermally treated at high temperature have high adsorption capacity for phosphate. However, its micron size (75 ㎛) limits its application to water treatment. In this study, we synthesized sepiolite impregnated polysulfone (PSf) beads to separate it easily from an aqueous solution. PSf beads with different sepiolite ratios were synthesized and their efficiencies were compared. The PSf beads with 30% impregnated sepiolite (30SPL-PSf bead) possessed the optimum sepiolite ratio for phosphate removal. Kinetic, equilibrium, and thermodynamic adsorption experiments were performed using the 30SPL-PSf bead. Equilibrium adsorption was achieved in 24 h, and the pseudo-first-order model was suitable for describing the phosphate adsorption at different reaction times. The Langmuir model was appropriate for describing the phosphate adsorption onto the 30SPL-PSf bead, and the maximum adsorption capacity of the 30SPL-PSf bead obtained from the model was 24.48 mg-PO4/g. Enthalpy and entropy increased during the phosphate adsorption onto the 30SPL-PSf bead, and Gibb's free energy at 35 ℃ was negative. An increase in the solution pH from 3 to 11 induced a decrease in the phosphate adsorption amount from 27.30 mg-PO4/g to 21.54 mg-PO4/g. The competitive anion influenced the phosphate adsorption onto the 30SPL-PSf bead was in the order of NO3- > SO42- > HCO3-. The phosphate breakthrough from the column packed with the 30SPL-PSf bead began after ~2000 min, reaching the influent concentration after ~8000 min. The adsorption amounts per unit mass of 30SPL-PSf and removal efficiency were 0.775 mg-PO4/g and 61.6%, respectively. This study demonstrates the adequate performance of 30SPL-PSf beads as a filter for phosphate removal from aqueous solutions.

Review of Adverse Events in Acupuncture Treatment (침치료 이상반응에 대한 고찰)

  • Park, Ji-Eun;Oh, Dal-Seok;Choi, Jun-Yong;Jung, So-Young;Kim, Ae-Ran;Koo, Chang-Mo;Jung, Hee-Jung;Choi, Sun-Mi
    • Korean Journal of Oriental Medicine
    • /
    • v.13 no.3
    • /
    • pp.79-85
    • /
    • 2007
  • Objective : To investigate documented surveys about adverse events of acupuncture therapy. Methods: We searched Medline with the terms of 'acupuncture/adverse event(s)', 'acupuncture/side effect(s)' and 'CAM/adverse event(s)' using Pubmed and set the limits to human study. Results: There were 5 prospective studies, 3 reviews and 3 surveys in our searching. There were 3 reports about acupuncture related adverse events in UK ranging from 10.7% to 15% of which the rate of significant events were from 0.13% to 0.14%. In Germany, there were 11% of acupuncture related adverse events in one report and 7.5%(significant events were 45 in 190,924 patients) in another report. In Australia, one study reported that every adverse event associated with acupuncture occurred in 8-9 month per one practitioner. In Japan, 0.14% of acupuncture related adverse events in 48 practitioners were reported in one systemic review. A cumulative review about significant adverse events associated with acupuncture reported 715 adverse events of which most frequent accidents were pneumothorax and central nervous system injury. Conclusion : The risk of adverse event associated with acupuncture is far lower than that associated with other general medical interventions. However, some safety guidelines about the acupuncture performance are needed.

  • PDF

A Development of NURBS-Based Pre and Post Processor for Structural Analysis of Free-Shaped Beam (자유형상 보요소 해석을 위한 NURBS기반의 전·후처리 모듈 개발)

  • Jung, Sung-Jin;Park, Se-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.16 no.10
    • /
    • pp.6673-6678
    • /
    • 2015
  • Recently, the free form buildings are constructed frequently. Exterior and interior components of these buildings have the free cross-section and a curved shape. So, There are many usages of classical finite element having tapered section and free-style shape. Some general commercial applications like ETABS, SAP2000, MIDAS are usually used for the safety evaluation of the free form structures. However, there are some limits in the accuracy of structural analysis and the length of analysis time because a very complicated finite element mesh have to be used. Therefore, In this study, a pre and post program module was developed to take advantage of general 3-D curved beam element which has a free-style curved shape and mathematical backgrounds. Pre-post processing module has been developed in this study was developed to control the curvature of the curved members by the NURBS control points. As a result, fast geometric modeling than was possible commercial applications. In addition, realistic depiction of the shape and behavior patterns were possible because of the free-form building allows visual check of the free form.

Analysis of Heavy Metals, Sulfur Dioxide and Residual Pesticides in Oriental Medical Materials at a Certain Oriental Medical Hospital (모 한방병원 한약재내 중금속과 이산화황 함량 및 잔류농약 분석 연구)

  • Cho, Woong-Hee;Cha, Yun-Yeop;Baik, Tai-Hyun;Kim, Byoung-Woo;Lee, Seung-Gi;Yoo, Jun-Sang;Sohn, Young-Joo;Sun, Seung-Ho
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.25 no.3
    • /
    • pp.489-495
    • /
    • 2011
  • The purpose of this study was to analyze harmful heavy metals, sulfur dioxide and residual pesticides in 30 kinds of oriental medical materials. This study was carried out on 30 samples of oriental medical materials. The examination's methods fallow the guideline of Food and Drug Administration. Inductively Coupled Plasma Mass Spectrometer (ICP-OES) was used to analyze lead, arsenic, cadmium. Mercury was analyzed by amalgamation method. A modified Monier-Williams method was used to analyze sulfur dioxide. The Gas Chromatography / Electron Capture Detector (GC/ECD) was used to analyze residual pesticides. Most of the results were within normal limits at baseline. but Cadmium was detected 0.523 mg/kg more than 0.3 mg/kg in Cinnamomi ramulus and Endosulfan was detected 11.595 mg/kg more than 0.2 mg/kg in Alismatis rhizoma. We needs to keep the quality of herbal medicines assessing and controling for safety of herbal medicines.

A Study about Introductory Plan of Automatic Wet Pipe Sprinkler System to Hydraulically Designed System (습식 스프링클러설비의 수리계산방식 도입방안에 관한 연구)

  • Park, Bong-Rae;Kong, Ha-Sung
    • Fire Science and Engineering
    • /
    • v.21 no.3
    • /
    • pp.69-77
    • /
    • 2007
  • Our country automatic wet pipe sprinkler system of hydraulically designed system has not deviated from the pipe regulation process, therefore we face limitations when using an independent method to hydraulically designed system. Therefore. after reviewing a developed country's methods using the drainage-density concept, we found it necessary for our country to introduce the drainage-density concept. Currently, under the National Fire Safety Codes(NFSC), this does not solve the problem and the limitation of hydraulically designed system because different problems arise depending on where the head was installed. To make improvements, first, such as the developed country, overcome the difference by introducing the drainage-density concept to determine the amount of drainage. Second, by using diverse head caliber and decreasing the limits on the amounts of distribution, we can expect a leveling off of the drainage density. Third, using the increase of hydraulically designed system through the application of the rule to hydraulically designed system, finally, development to performance based fire protection design.

Investigation of Health Hazards in the Underground Storage Facilities of Ginger Roots (생강 저장굴에서 발생한 건강 피해의 원인 조사)

  • Bae, Geun-Ryang;Lim, Hyun-Sul
    • Journal of Preventive Medicine and Public Health
    • /
    • v.35 no.1
    • /
    • pp.72-75
    • /
    • 2002
  • Objectives : To evaluate the health hazards in the underground storage facilities of ginger roots. Methods : The authors reviewed the emergency rescue records from the Seosan fire department over the period Jan 1, 1996 to Aug 31, 1999. The atmospheres in 3 different underground storage locations were analyzed for $O_2,\;CO_2,\;CO,\;H_2S\;and\;NH_4$. Results : From the emergency records, we were able to identify 20 individuals that had been exposed to occupational hazards in the underground storage facilities. Among these 20 cases, 13 were due to asphyxiation (resulting in f deaths) and 7 were due to falls. In the first atmospheric tests, peformed on Feb 25, 1998, the O2 level inside the underground storage facility, located about $5{\sim}6$ meters below the surface, was 20.6% and the $CO_2$ level was about 1,000 ppm. CO, $H_2S\;and\;NH_4$ were not detected. In the second tests on Jul 6, 1999, measurements of the $O_2$ level at 3 meters below the surface in two different storage locations were 15.3 and 15.1%. And the $O_2$ levels inside the storage facilities were 12.2 and 12.1%. The $CO_2$ level was above 5,000 ppm (beyond upper limits of measurement). CO, $H_2S\;and\;NH_4$ were not detected. Conclusions : We conclude that asphyxiation in the underground storage facilities for ginger roots was not due to the presence of toxic gases such as CO, $H_2S\;and\;NH_4$, but rather the exclusion of oxygen by carbon dioxide was responsible for causing casualties. For the development of a hazard free working environment, safety education as well as improvements in storage methods are needed.