• Title/Summary/Keyword: safety limits

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Monitoring of Heavy Metal Contents in Commercial Herbal Medicines in Korea: Cultivated Herbal Medicines in the Seoul and Daegu Areas (국내 유통 한약재의 중금속 함량 모니터링 -서울과 대구지역 한약재 중심으로 -)

  • Jang, Seol;Lee, Ah-Reum;Lee, A-Eong;Choi, Go-Ya;Kim, Ho-Kyoung
    • Journal of Environmental Health Sciences
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    • v.41 no.1
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    • pp.30-39
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    • 2015
  • Objectives: This study was conducted to determine the heavy metal contents in commercial herbal medicines in Korea. Methods: Monitoring of lead, arsenic, cadmium and mercury was carried out on 116 samples of eleven types of herbal medicines. Among the total samples, 71 samples were domestic and 45 were imported. The samples were digested using the microwave method. The heavy metal contents were measured by inductively coupled plasma atomic emission spectrometry (ICP-AES) and a mercury analyzer. ICP-AES was used to analyze lead, arsenic cadmium. Mercury was analyzed by the amalgamation method. Results: The mean values of the heavy metal contents in the herbal medicines were Pb 0.64mg/kg, As 0.26mg/kg, Cd 0.07mg/kg and Hg 0.004mg/kg. Of the total samples, one violated the MFDS (Ministry of Food and Drug Safety) regulatory guidance on heavy metals in herbal medicines. Lead was detected at more than 5mg/kg in one sample. The measured values of arsenic, cadmium and mercury in the herbal medicines showed levels lower than the recommended levels for herbal medicines in MFDS regulatory guidance. In the comparison of domestic samples with imported herbal medicines, it was found that one domestic sample surpassed the maximum residue limits for lead. Conclusion: These results will be used to establish the regulation and control of heavy metal contents in herbal medicines. In addition, continuous monitoring is needed to ensure confidence in and the safety of these herbal medicines.

A study on the development of generalization method for SD spatial information for e-Navigation (e-Navigation을 위한 SD 공간정보 일반화 기법 개발에 관한 연구)

  • Ko, Hyun-Joo;Oh, Se-Woong;Sim, Woo-Sung;Suh, Sang-Hyun;Youn, Chung
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2012.06a
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    • pp.85-86
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    • 2012
  • e-Navigation strategy IMO promotes is defined as it is necessary to network to provide various maritime safety information to in land and on board users, and it is expected to provide a large amount and diverse kinds of maritime spatial information services to them frequently. However, as there are some limits to transmit that by current mobile maritime communication technologies, it is required to simplify and optimize the information. In this study, tree node and convex hull method is applied to S-100 SD spatial information to generalize and we arranged the efficiency and effect of generalization by storing in XML form which can be used in general.

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HEAT TRANSFER ANALYSIS OF CONCRETE STORAGE CASK DEPENDING ON POROUS MEDIA REGION OF SPENT FUEL ASSEMBLY (사용후핵연료 집합체의 다공성 매질 적용영역에 따른 콘크리트 저장용기 열전달 해석)

  • Kim, H.J.;Kang, G.U.
    • Journal of computational fluids engineering
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    • v.21 no.4
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    • pp.33-39
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    • 2016
  • Generally, thermal analysis of spent fuel storage cask has been conducted using the porous media and effective thermal conductivity model to simplify the structural complexity of spent fuel assemblies. As the fuel assembly is composed of two regions; active fuel region corresponding to UO2 pellets and unactive fuel region corresponding to the top and bottom nozzle, the heat transfer performance can be influenced depending on porous media application at these regions. In this study, numerical analysis on concrete storage cask of spent fuel was performed to investigate heat transfer effects for two cases; one was porous media application only to active fuel region(case 1) and the other one was porous media to whole length of fuel assembly(case 2). Using computational fluid dynamics code, the three dimensional, 1/4 symmetry model was constructed. For two cases, maximum temperatures for each component were evaluated below the allowable limits. For the case 1, maximum temperatures for fuel cladding, neutron absorber and baskets inside the canister were slightly higher than those for the case 2. In particular, even though the helium flows with low velocity due to buoyant forces occurred at the top and bottom of unactive fuel region, treating only active fuel region as the porous media was ineffective in respect of the heat removal performance of concrete storage cask, implying a conservative result.

Comparison of Sampling and Analytical Methods for Determining Airborne Hexavalent Chromium -Limit of Detection, Accuracy and Precision of Analytical Procedures (공기중 6가 크롬 측정 방법 비교 -검출한계, 정확도 및 정밀도-)

  • 신용철;이병규;이지태
    • Journal of Korean Society for Atmospheric Environment
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    • v.18 no.1
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    • pp.39-49
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    • 2002
  • In this study, limits of detection (LOD), accuracy and precision of four sampling/ analytical methods were evaluated and compared for the determination of airborne hexavalent chromium, Cr (VI). The methods include : (1) a combination of the National Institute for Occupational Safety and Health (NIOSH) Method 7600/U. S. Environmental Protection Agency (EPA) Method 218.6 (NIOSH/EPA Method) proposed by Shin and Paik, 2) two impinger methods using 2% NaOH/3% Na$_2$CO$_3$. (3) same as (2) but with 0.02 N NaHCO$_3$absorbing solution, and (4) the Occupational Safety and Health (OSHA) Method ID-215. An ion chromatograph/visible absorbance detector was used for the analysis of Cr (VI) in sample solution. Limit of detection (LOD) , analytical accuracy, and precision were also tested using Cr (VI) spike samples. Recoveries (as index of accuracy) and coefficient of variation (CV) (as a index of precision) were determined. Two-way ANOVA and Turkey's test were performed to test the significance in differences among recoveries and CVs of the methods. In all the methods, the peaks of Cr (VI) were separated sharply on chromatograms and exhibited a strong linearity with Cr (VI) concentrations in solution. The correlation coefficients of calibration curves typically ranged from 0.9997 to 0.9999, and the analytical LODs from 0.025 to 0.1$\mu\textrm{g}$/sample. All the method had good sensitivities and linearities between Cr (VI) levels and peak areas. The accuracies (% mean recoveries) of the methods ranged from 80.1 to 104.2%, while the precisions (pooled coefficient of variation) ranged from 3.16 to 4.43%. The impinger methods showed higher recoveries ( > 95%) than those of the PVC filter methods (the OSHA Method and the NIOSH/EPA Method). It was assumed that Cr (VI) on PVC filter was exposed to air and reduced to trivalent chromium, Cr (III), whereas it was stabilized in alkali solution contained in impinger. Thus, a special treatment of Cr (VI) samples collected on PVC filters may be required.

A Study on the Effects of I&C Systems by EMI Generating from Corona Discharge at Transformer Area (변압기 지역 코로나 전자파 간섭에 의한 계측제어설비 영향에 관한 연구)

  • Min, Moon-Gi;Lee, Jae-Ki;Park, Jin-Yeub;Kim, Hee-Je
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.2
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    • pp.266-271
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    • 2014
  • The Electromagnetic Interference(EMI) generating from corona discharge of transformer area can interference the digital Instrument and Control(I&C) systems located nearby transformers. When the potential gradient of the electric field around the conductor is high enough to form a conductive region but not high enough to cause electrical breakdown to nearby objects, the EMI of corona discharge emits with the conducted and radiated noise and it interferences the signals of the I&C systems. Since digital I&C systems have an efficiency and competitive price, the analog I&C systems have been upgraded and displaced with the digital I&C systems but which have less EMI Immunity. There was no assessment to I&C systems by EMI generating corona discharge nearby transformers. When the safety-related I&C systems are installed in plants, the verification of equipment EMI should be done not in site-specific test but in test facilities. There are the need to do the site-specific EMI evaluation of corona discharge nearby transformers. This paper assesses the margin between plant emission limits and the highest composite plant emission of corona. When the non safety-related I&C systems are placed in transformer area, it suggests the appropriate radiated susceptibility level to EMI of corona discharge.

A Study on the Development of an RFID System for Recreational Boating Safety (RFID 기술을 활용한 해양인명구조 시스템 개발에 관한 연구)

  • Yang, Dong-Shin;Sung, Chul;Choi, Tae-Sung
    • Proceedings of KOSOMES biannual meeting
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    • 2006.11a
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    • pp.119-123
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    • 2006
  • Finding out the exact location of survivors in short period of time is critical to conduct rescue activity successfully in oceans. Current technology with natural circumstances limits the activity that our efforts come along. R&D Center housed at Korea Coast Guard (KCG) has developed the system named "RFID for Life jacket" which enables us to access the location of persons under distressed situation. The RFID has been widely known as state-of-art technology to monitor the location even in inland or in ocean. Composed of tag, antenna. reader and middleware, RFID is attached to attached to a life jacket that people usually wears in recreational activity. By conducting experiments in pilot-scale several times, successful results showing 96.7% of transmission within 3.5km in diameter were produced. This study explains the routes of experiments to reach the goal and expected results coming from this accomplishments.

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Coastal State's Jurisdiction over Suspected Vessels on the High Seas - In relation to the case of F/V Jin Yinn in USA - (공해상의 범죄혐의 선박에 대한 연안국의 관할권 - 미국의 F/V JIN YINN호 사건등과 관련하여 -)

  • Kim, Jong-Goo
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.17 no.1
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    • pp.47-52
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    • 2011
  • On the high seas, under international law, a ship is subject to the jurisdiction of the state whose flag she flies. Vessels of any flag are free to navigate the high seas without interference from other states. Thus, there are certain limits of coastal state's exercising law enforcement jurisdiction over a foreign flag vessel on the high seas. However, there are exceptions to exclusive flag state jurisdiction. One of them is the theory of constructive presence. The other is theory of partial execution. Korea Coast Guard's law enforcement authority should be exercised more actively based on those theories supported by the international cases.

Determination of Analytical Method for the Insecticide Clothianidin and its Metabolites in Soil and Surface Water (토양 및 토양수 중 살충제 Clothianidin 및 대사산물 잔류분석법 확립)

  • Choi, Young-Joon;Kwon, Chan-Hyeok;Han, Byung-Soo;Lee, Young-Deuk
    • Korean Journal of Environmental Agriculture
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    • v.33 no.2
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    • pp.69-77
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    • 2014
  • BACKGROUND: The purpose of this study was to investigate the effects of clothianidin on the soil in terms of clothianidin dissipation and degradation to evaluate its safety in order to provide an analytical foundation for clothianidin and the 5 metabolites related to it. METHODS AND RESULTS: High-performance liquid chromatography(HPLC) was used to separate clothianidin and its metabolites in this study. In soil, after suppressing dissociation-proned ions with weak alkalic $NH_4OH$ and extracting the metabolites with methanol, clothianidin, Methylaminoimidazole(MAI), Methylnitroguanidine(MNG), Thiazolylmethylurea(TZMU) and Thiazolylnitroguanidine(TZNG). Thiazolylmethylguanidine(TMG) were extracted with the addition of neutral $NH_4OAC$ to increasing the intensity of ions. Compounding elements were separated by using Hydrometrix ($ChemElut^{TM}$) and ion-exchanging Solid-phase extraction(SPE) Strong cation-exchanger(SCX) and C18 were used. The recovery rates of clothianidin and 5 metabolites in soil and water ranged from 87.4% to 104.3%. A standard deviation of our analysis for the soil and water samples were less than 5%. CONCLUSION: Well accepted detection limits for clothianidin and 5 metabolites in soil samples based on a dissipation analysis is 0.005 mg/kg and 0.001 mg/L in water samples. The dissipation concentration of this study was decided to be enough to evaluate the dissipation levels of clothianidin and its metabolites.

Microbiological Evaluation for HACCP Implementation of Wholesale Bakery Products (제빵업체의 HACCP 모델 적응을 위한 미생물학적 위해도 평가)

  • Kim Hye Young;Park Jae Young;Chung Duck Hwa;Oh Sangsuk
    • Journal of Food Hygiene and Safety
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    • v.19 no.4
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    • pp.185-192
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    • 2004
  • Generic HACCP models for bakery products may help HACCP implementation at the wholesale bakery production lines easier. When baking, the internal temperature of bakery products went up to $85^{\circ}C$, which resulted in gelatinization of starch. Considering the characteristics of bakery products, general sanitation control procedures are the main target tool to keep bakery products safe. Monitoring of pathogenic microorganisms at bakery plant environment including production lines was carried out. At the wholesale bakery environment pathogenic microorganisms were detected. It gave a clue that general sanitation control procedures should be implemented for safe bakery products supply. Hazard analysis of raw materials and processing of bakery products, and determination of critical control points and critical limits at the wholesale bakeries lead to present generic model of bakery product HACCP plan. CCPs for the wholesale bakery products may be applied and modified for the implementation of HACCP plan at the wholesale bakery plant.

A Comparative Study of the Detectable Methods of Residual Antibiotics in Milk (우유중 잔류 항생물질 분서방법에 관한 비교연구)

  • 백선영;김형일;박건상;김소희;권경란
    • Journal of Food Hygiene and Safety
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    • v.11 no.2
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    • pp.129-132
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    • 1996
  • Recently, as concern about the residual antibiotics in milk increase, the detection methods of residual antibiotics used extensevely at the present time were investigated and compared to their properties and the detection limits of variable antibiotics. At first, comparactive tests of the detectable sensitivity of 4 test organisms, B. cereus, B. subtilis, M.luteus, B.stearothermophilus C-953, were performed by disc assay. As a result, B.stearothermophilus was the most sensitive strain of all other strains and showe the detect limit of 5-50 ppb for penlicillins (PCs). And also, B.subitilis was showed the more effective detection limit, 200-400 ppb, for aminoglycosides (AGs) and M.luteus was showed predominant sensitivity , 50-500 ppb for macrolides(MLs) and B.cereus was the most sensitive strain for tetracyclines (TCs) and showed the detection limit of 100-400 ppb. Therefore, each test strains were showed a different sensitivity in the detection of the different antibiotic families. When the detection limit of disc assay and other methods were compared, TTCmethod was less sensitive than other methods showing 5-50 ppb detectable lebel for PCs. Also, for the detection of other antibiotic families TTC method was showed the worst sensitivity and Delvo and Charm Farm tests were similar to the detectable properties of AGs and MLs. Although disc assay was showed the similar detection limit for PCs with Delvo and Charm Farm, it was more widely effective for the detection of kanamycin, erythromycin, chlortetracycline, doxycycline, verginiamycin and so on than Delvo or Charm Farm. CharmII test was showed the best sensitivity for the most of antibiotics except neomycin and gentamycin. But it was necessary that different tests must be performed to each antibiotic family and so it was regarded that the effectiveness of that method was low.

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