• Title/Summary/Keyword: safety examination

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A study on the modular design of smart photonic sports clothing based on optical fiber technology (광섬유 기반 스마트 포토닉 스포츠 의류의 모듈화 디자인 연구)

  • Park, Soo-Jin;Park, Sun-Hyeong;Lee, Joo-Hyeon
    • Science of Emotion and Sensibility
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    • v.12 no.4
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    • pp.393-402
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    • 2009
  • The objectives of this study is to search for systematic modular design methods for smart photonic sports clothing based on light emitting optical fiber technology related to smart photonic clothing, and to present a variety of modular design models based on optical fiber and light emitting module assembly technology, both of which stand on the basis of body measurements. To achieve the objectives, this paper firstly reviewed the concept of smart photonic clothing and related technologies, and an examination of the concepts of modularization and its designs, as well as examples of modularization used in various fields. To decide the size and attachment point of optical fiber and light emitting modules, the study considered the close connection between modularization and body measurements. Along with body measurements, to derive the most suitable region to attach the optical fiber and light emitting modules, appropriate attachment locations for computing devices and regions which are marginally affected by body movements, were analyzed. On the basis of the results, a modular model of a sports jacket with smart photonic functions was designed and presented, with the focus on the wearer's safety and protection function, which was judged to be the most needed and appropriate function among the three functions of smart photonic clothing related to sports clothing. The results of this study is expected to be useful as basic data for future smart photonic clothing design research.

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Population-Based Intervention for Liver Fluke Prevention and Control in Meuang Yang District, Nakhon Ratchasima Province, Thailand

  • Kompor, Pontip;Karn, Rattikarn Muang;Norkaew, Jun;Kujapun, Jirawoot;Photipim, Mali;Ponphimai, Sukanya;Chavengkun, Wasugree;Paew, Somkiat Phong;Kaewpitoon, Soraya;Rujirakul, Ratana;Wakhuwathapong, Parichart;Phatisena, Tanida;Eaksanti, Thawatchai;Joosiri, Apinya;Polsripradistdist, Poowadol;Padchasuwan, Natnapa;Kaewpitoon, Natthawut
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.685-689
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    • 2016
  • Opisthorchiasis is still a major health problem in rural communities of Thailand. Infection is associated with cholangiocarcinoma (CCA), which is found frequently in Thailand, particularly in the northeastern. Therefore, this study aimed to evaluate the effectiveness of health intervention in the population at risk for opisthorchiasis and CCA. A quasi-experimental study was conducted in Meuang Yang district, Nakhon Ratchasima province, northeastern Thailand, between June and October 2015. Participants were completed health intervention comprising 4 stations; 1, VDO clip of moving adult worm of liver fluke; 2, poster of life cycle of liver fluke; 3, microscopy with adult and egg liver fluke; and 4, brochure with the knowledge of liver fluke containing infection, signs, symptoms, related disease, diagnosis, treatment, prevention, and control. Pre-and-post-test questionnaires were utilized to collect data from all participants. Students paired t-tests were used to analyze differences between before and after participation in the health intervention. Knowledge (mean difference=-7.48, t=-51.241, 95% CI, -7.77, -7.19, p-value =0.001), attitude (mean difference=-9.07, t=-9.818, 95% CI=-10.9, -7.24, p-value=0.001), and practice (mean difference=-2.04, t=-2.688, 95% CI=-3.55, -0.53, p-value=0.008), changed between before and after time points with statistical significance. Community rules were concluded regarding: (1) cooked cyprinoid fish consumption; (2) stop under cooked cyprinoid fish by household cooker; (3) cooked food consumption; (4) hygienic defecation; (5) corrected knowledge campaign close to each household; (6) organizing a village food safety club; (7) and annual health check including stool examination featuring monitoring by village health volunteers and local public health officers. The results indicates that the present health intervention program was effective and easy to understand, with low cost and taking only a short time. Therefore, this program may useful for further work at community and provincial levels for liver fluke prevention and control.

Oxidative Stress of Mouse Fed Irradiated Diet Containing High Unsaturated Fatty Acid (방사선 조사된 고불포화지방산 식이를 섭취한 Mouse의 산화적 스트레스)

  • Seo, Dae-Young;Park, Sun-Young;Kang, Myoung-Hee;Suh, Kwang-Sun;Ly, Sun-Yung
    • Journal of Nutrition and Health
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    • v.39 no.7
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    • pp.599-609
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    • 2006
  • In this study, we investigated the in vivo effect by intake of the irradiated foods such as mackerel and sesame seed which are high in unsaturated fatty acid through TBARS (thiobarbituric acid reactive subtance) and the tissue pathological and genotoxicological test. Thirty two ICR mice are divided into four groups, one non-irradiated (control) group and three irradiated (5, 10, 20 kGy, respectively) groups. Sesame seed and pulverized mackerel in modified AIN93M diet were mixed together then divided into four identical parts. Three parts of them were irradiated by doses of 5, 10, and 20 kGy. These experimental diet were fed to each group for 4, 8 and] 6 weeks. The results of the study were as follows: No significant differences in weight gain were found in each group. Peroxide value of the irradiated diet was higher than that of the non-radiated one and also increased according to the storage period. TBA values in plasma, liver, kidney and Peyer's patch were not significantly different among 4 groups. DNA% in tail, tail length (TL) and tail moment (TM) values of the blood lymphocyte in 4, 8 and 16 week groups and the liver in 16 week group were much measured over the control DNA % in tail of kidney of 8 week group was significantly than the control and TL and TM of 8 week and TM of 16 week groups showed a tendency of higher values. By Peyer's DNA % in tail of 8 week group, DNA % in tail and TM of 16 week groups increased significantly over the control, Ultrastructural examination shows myeline figures and swollen mitochondria in parietal cells and intestinal epithelial cells of 8 and 16 weeks groups. After this study, we need further investigations on the safety of highly consumed foods which contain high contents of unsaturated fatty acid, largely imported and which are possible to be irradiated.

The Role of Exposure Assessment of Humidifier Disinfectant (HD) in the Program to Monitor HD Associated Health Problems (가습기 살균제 건강영향 모니터링에서 환경노출조사의 역할)

  • Park, Soyoung;Park, Ju-Hyun;Lee, Seunghee;Jang, Woo-Sung;Kim, So-Yeon;Park, Jihoon;Mun, Eunchan;Lee, Yesung;Kim, Hyunil;Kim, Hyeong-Cheol;Park, Dong-Uk
    • Journal of Environmental Health Sciences
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    • v.46 no.2
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    • pp.224-231
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    • 2020
  • Objective: The objectives of this study are to update the information on the characteristics of humidifier disinfectant (HD) usage with HD associated health problems and to discuss the role of HD exposure assessment in the national program to monitor health problems in patients with HD associated diseases. Method: A total of 201 HD associated patients who registered to undergo clinical examination at Kangbuk Samsung Hospital was interviewed to acquire their responses regarding several HD use characteristics, including type of HD brands used, HD use duration, average daily HD use hours, and the volume of the room in which HD was used. The responses of the HD associated patients to HD use-related questions were compared between responses in the lung injury investigation and this study. Results: The responses of HD associated patients in this study were found to be different from those in the lunginjury investigation. In particular, some of the patients who had not answered in the lung-injury investigation were able to answer thanks to assistance from the investigator in this study. For their responses regarding the name of the most commonly used HD brand, the number of patients who did not answer (N=11) was reduced to eight in this study. Significant changes in the responses of study subjects to questions related to HD use were achieved through the interview in this study. Conclusion: This study found significant changes in the responses regarding HD use characteristics. HD exposure assessment should be included in the program in order to allow surveillance of HD associated health problems.

Toxicity Evaluation of 30 kGy Irradiated Dried Space Bibimbap for Three Months (우주식품으로 개발한 30 kGy 감마선 조사된 건조우주비빔밥의 3개월 독성평가)

  • Park, Jae-Nam;Kim, Jin-Kyung;Choi, Dan-Bi;Kim, Jae-Hun;Song, Beom-Seok;Lee, Ju-Woon;Kang, Il-Jun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.7
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    • pp.956-961
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    • 2011
  • This study was conducted to evaluate the possible subacute toxicity of gamma-irradiated dried bibimbap. The dried bibimbap was irradiated at the dose of 30 kGy at room temperature. For the animal study, the male and female ICR mice (8 mice per group) had the diet with AIN39G as control and dried bibimbap 30 kGy irradiated and non-irradiated for three months. During the experimental period, the group with 30 kGy irradiated bibimbap did not show any changes in appearance, behavior, mortality, body weight, organ weight, and food consumption compared to the control. Also, all of the biochemical parameters were observed in the normal ranges. In histopathological examination including hematological and serum biochemical analyses, there were no significant differences among the control and 30 kGy irradiated dried bibimbap groups. These results indicate that irradiation of bibimbap up to 30 kGy did not cause any toxic effects and could be applied for the development of safe ready-to-cook food.

A Study for Unsaturated-Character of Weathered Granite Soil in Korea (국내 화강풍화토의 불포화 특성에 관한 연구)

  • Lee, Hyoungkyu;Lee, In
    • Journal of the Korean GEO-environmental Society
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    • v.10 no.3
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    • pp.13-20
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    • 2009
  • Generally, soil is regarded as fully saturated in Geotechnical Engineering and under ground structure design. Because it is in convenience and safety. But soils treated in field are almost in unsaturated state. Design in unsaturated state is difficult comparing with saturated soil. In unsaturated soil mechanics, parameters are usually not constant unlike saturated soil mechanics. Additionally lab or field tests in unsaturated soil mechanics are required more cost, time and theoretical difficulty. One of essential requisites for examination about unsaturated soil is Soil-Water Characteristic Curve (SWCC). It show the relation between soil suction and soil water content. Through many studies in and out of country, computation and testing methods for SWCC were introduced. But in this the country, most soil is granite soil that is widely spread in Korea. And the studies for granite soil's SWCC are not enough yet. In this paper, through studying for existing proposal methods about computation SWCC and collection data for domestic granite soils, It was determined the suitable method for domestic granite soils, and computed each granite soil's SWCC. The purpose of this paper is establishing database for domestic granite soil's SWCC as each region to convenience for applying to actual affairs. For this, studying about existing proposal methods for SWCC was performed and a computer program Soil-Vision is used. Furthermore for verification theoretical and testing methods were also performed.

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Evaluation of Peri-procedural Warfarin Therapy Undergoing Cardioversion in Patients with Atrial fibrillation (심방세동 환자의 심율동전환 시행 전·후 warfarin 치료의 적절성 평가)

  • Moon, Jung-Yeon;Kim, Bo-Ram;Jo, Eun-Jung;Cho, Yoon-Sook;Han, Hyun-Joo;Choi, Eue-Keun
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.3
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    • pp.201-206
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    • 2016
  • Objective: Direct current cardioversion for atrial fibrillation could be associated with the risk of thromboembolic events. Anticoagulation therapy with warfarin (INR 2.0-3.0) is recommended 3 weeks before and 4 weeks after cardioversion to reduce the risk of thromboembolism. This study evaluated warfarin therapy in pharmacist-managed anticoagulant services (ACS). Methods: This retrospective study was performed in 106 patients with atrial fibrillation from 2012 to 2013. The primary efficacy endpoint was the composite of stroke, transient ischemic attack, myocardial infarction, and cardiovascular death. The primary safety measure was major bleeding. To evaluate the peri-procedural effects of warfarin treatment, we studied whether target INR was maintained, as well as the maintenance period of the therapeutic range. Quality of treatment was measured by time in therapeutic range (TTR) by using the Rosendaal method. Results: There were no thromboembolic events, but TEE examination at time of cardioversion showed a left atrial thrombus in three patients (2.8%). Bleeding complications after cardioversion occurred in 2 patients (1.9%). The average INR value at the time of cardioversion was $2.59{\pm}0.8$, and was within the therapeutic range in 83 patients (78%). Analysis of the patients in whom the value was within the therapeutic range twice consecutively showed that the ratio of TTR was 80% and the therapeutic range was maintained in 67 patients (63%) for an average of 4.90 weeks prior to cardioversion. Similarly, 76 patients (72%) had a stable INR within the therapeutic range for an average of 5.70 weeks and a mean TTR of 83%. Conclusion: Pharmacists significantly contributed to appropriate warfarin treatment with close monitoring during cardioversion. Likewise, active pharmacist monitoring and systemic management should be considered to reduce thromboembolism and bleeding complications in the peri-cardioversion period.

Floristic Study of Daeheuksando in Korea (대흑산도의 관속식물상)

  • Jang, Chang-Seok;Yang, Sun-Gyu;Jang, Hyun-Do;Lee, Ro-Young;Park, Min-Su;Kim, Ki-Hong;Oh, Byoung-Un
    • Korean Journal of Plant Resources
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    • v.27 no.5
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    • pp.518-533
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    • 2014
  • The flora in the region of Daeheuksando ($N34^{\circ}37^{\prime}{\sim}34^{\circ}42^{\prime}$, $E125^{\circ}23^{\prime}{\sim}125^{\circ}38^{\prime}$) was surveyed from June 2010 to October 2011. The vascular plants from 22 field surveys were revealed to total of 496 taxa: 113 families, 316 genera, 446 species, four subspecies, 43 varieties and three forms. 124 taxa were the first records from this region. This field study discovered significant plants in various categories. Korean endemic plants numbered 7 taxa, and 6 taxa designated by Korean Forest Service as rare plants were investigated in this region. The taxa in the category II of rare and endangered plants and higher than the third degree among the floristic regional indicator plants designated by Korean Ministry of Environment were one taxon and 47 taxa, respectively. Especially, it was proved that Spiraea chartacea, Hosta yingeri, Hemerocallis hongdoensis and Saussurea polylepis were endemic to Heuksan-myeon including Daeheuksando in Korean peninsular. In addition, the naturalized plants of 46 taxa were recorded.

Biochemical Responses in Olive Flounder, Paralichthys olivaceus Fed Diet Supplemented with Fermented Aquaculture Sewage (양식장 배출물 발효물의 사료첨가에 따른 넙치, Paralichthys olivaceus의 생화학적 반응)

  • Jee, Jung-Hoon;Moon, Sang-Wook;Kim, Se-Jae;Lee, Young-Don;Keum, Yoo-Hwa;Kang, Ju-Chan
    • Journal of fish pathology
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    • v.18 no.2
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    • pp.187-195
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    • 2005
  • Effluent of aquaculture industry has caused a growing concern regarding its environmental impact. We assessed the use of flounder farming sewage as supplement of diet, to minimize the impact of aquaculture on the environment or also establish the technique for the recycling of effluent sediment derived from land-based seawater fish farm. In order to investigate the effects of a fermented aquaculture waste on biochemical responses of olive flounder (Paralichthys olivaceus), fermented products of aquaculture wastes were used as test compounds that cause hepatic and renal stress through the induction of oxidative stress in liver and kidney. Hepatosomatic index (HSI), glutathione content and glutathione dependent enzyme were not significantly different and no correlation was found within the different types of fermentation condition or supplement concentration, except for significant increases in 50% fermentation group and 50% concentration group in case of glutathione peroxidase activity and HSI value, respectively. These results showed addition of fermented aquaculture sewage may be an economic artificial sources of diet for fish aquaculture practices without affecting the function and safety in view of biochemical examination.

Characterization of Trichosporonoides madida and Evaluation of Virulence in Laboratory Animals (Trichosporonoides madida 균주의 성상 및 실험동물에 대한 병원성)

  • Jong-Bae Kim;Young-Mi Kim;Sang-Wook Park
    • Biomedical Science Letters
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    • v.3 no.2
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    • pp.77-82
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    • 1997
  • One of the most important prerequisites of the industrial microorganism is that it should not be virulent to humans or economically important animals or plants. In this investigation, the microbiological characterization of T. madida N-5-3 strain was performed. And then, the virulence of the test strain in mouse model was examined systematically. The microbiological characteristics of the test strain were found to be fully consistent with those of typical T. madida. The i.p. lethal dose(LD)$_{50}$ of the test strain was greater than 1$\times$10$^8$, because there was no dead animal with the challenge doses upto the level of 1$\times$10$^8$. When 1$\times$10$^8$ yeast cells were challenged to the laboratory mice, T. madida N-5-3 strain was completely cleared from the liver and spleen in 4 days after challenge. And no pathological changes in the histological examination of the internal organs from challenged mice was observed. Above results can provide the predictability of the safety of T. madida N-5-3 strain for the industrial use in the view point of the public health aspect.

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