• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.3
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• pp.268-278
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• 2021

Technologies that are leading the fourth industrial revolution, such as the Internet of Things (IoT), big data, artificial intelligence (AI), and cyber-physical systems (CPS) are developing and generalizing. The demand to improve productivity, economy, safety, etc., is spreading in various industrial fields by applying these technologies. Digital twins are attracting attention as an important technology trend to meet demands and is one of the top 10 tasks of the Korean version of the New Deal. In this study, papers, magazines, reports, and other literature were searched using Google. In order to investigate the contribution or role of geospatial information in the digital twin application, the definition of a digital twin, we investigated technology trends of domestic and foreign companies; the components of digital twins required in manufacturing, plants, and smart cities; and the core techniques for driving a digital twin. In addition, the contributing contents of geospatial information were summarized by searching for a sentence or word linked between geospatial-related keywords (i.e., Geospatial Information, Geospatial data, Location, Map, and Geodata and Digital Twin). As a result of the survey, Geospatial information is not only providing a role as a medium connecting objects, things, people, processes, data, and products, but also providing reliable decision-making support, linkage fusion, location information provision, and frameworks. It was found that it can contribute to maximizing the value of utilization of digital twins.

• Journal of Cadastre & Land InformatiX
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• v.51 no.1
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• pp.53-65
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• 2021

C-ITS(Cooperative Intelligent Transport System) that pursues traffic safety and convenience uses various sensors to generate traffic information. Therefore, it is necessary to improve the sensor-related technology to increase the efficiency and reliability of the traffic information. Recently, the role of CCTV in collecting video information has become more important due to advances in AI(Artificial Intelligence) technology. In this study, we propose to identify and track dynamic objects(vehicles, people, etc.) in CCTV images, and to analyze and provide information about them in various environments. To this end, we conducted identification and tracking of dynamic objects using the Yolov4 and Deepsort algorithms, establishment of real-time multi-user support servers based on Kafka, defining transformation matrices between images and spatial coordinate systems, and map-based dynamic object visualization. In addition, a positional consistency evaluation was performed to confirm its usefulness. Through the proposed scheme, we confirmed that CCTVs can serve as important sensors to provide relevant information by analyzing road conditions in real time in terms of road infrastructure beyond a simple monitoring role.

• Design & Manufacturing
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• v.15 no.2
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• pp.11-16
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• 2021

Recently, three-dimensional (3D) cell culture systems, which are superior to conventional two-dimensional (2D) vascular systems that mimic the in vivo environment, are being actively studied to reproduce drug responses and cell differentiation in organisms. Conventional two-dimensional cell culture methods (scaffold-based and non-scaffold-based) have a limited cell growth rate because the culture cannot supply the culture medium as consistently as microvessels. To solve this problem, we would like to propose a 3D culture system with an environment similar to living cells by continuously supplying the culture medium to the bottom of the 3D cell support. The 3D culture system is a structure in which microvascular structures are combined under a scaffold (agar, collagen, etc.) where cells can settle and grow. First, we have manufactured molds for the formation of four types of microvessel-mimicking chips: width / height ①100 ㎛ / 100 ㎛, ②100 ㎛ / 50 ㎛, ③ 150 ㎛ / 100 ㎛, and ④ 200 ㎛ / 100 ㎛. By injection molding, four types of microfluidic chips were made with GPPS (general purpose polystyrene), and a 100㎛-thick PDMS (polydimethylsiloxane) film was attached to the top of each microfluidic chip. As a result of observing the flow of the culture medium in the microchannel, it was confirmed that when the aspect ratio (height/width) of the microchannel is 1.5 or more, the fluid flows from the inlet to the outlet without a backflow phenomenon. In addition, the culture efficiency experiments of colorectal cancer cells (SW490) were performed in a 3D culture system in which PDMS films with different pore diameters (1/25/45 ㎛) were combined on a microfluidic chip. As a result, it was found that the cell growth rate increased up to 1.3 times and the cell death rate decreased by 71% as a result of the 3D culture system having a hole membrane with a diameter of 10 ㎛ or more compared to the conventional commercial. Based on the results of this study, it is possible to expand and build various 3D cell culture systems that can maximize cell culture efficiency by cell type by adjusting the shape of the microchannel, the size of the film hole, and the flow rate of the inlet.

• Journal of the Korean Association of Geographic Information Studies
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• v.24 no.1
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• pp.54-67
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• 2021

At present, CPTED projects are showing an effect such as reducing the anxiety of residents from crimes and improving the criminal environment about crimes through crime prevention. However, most of the CPTED programs have been implemented mainly to improve the physical environment without verifying systematically and empirically on the relationship between the program and improving the quality of life of residents and satisfaction level of residents etc. Accordingly, the objective of this study is to grope for a plan to apply CPTED to urban regeneration for improvement in the safety and life quality of residents using AHP and Visualizing The Mental Map. For this, We selected four case areas in Busan and then analyzed the dead zones of CPTED programs by visualizing the mental maps and heat maps of residents for case districts. As a result of evaluating the priority of CPTED program, installation of CCTVs and streetlights for prevention of crimes was found to be the most important elements. Result of analyzing mental map, the existing crime prevention facilities and CPTED programs were found to have resolved most of physical disorder. However, it showed that, for psychological factors which the residents feel such as social disorder, a number of dead zones exist.

• CELLMED
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• v.11 no.3
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• pp.13.1-13.9
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• 2021

Background and Objective: Nux-vomica based traditional Unani formulation, Habb-e-Azaraqi (HAZ) is an important drug used by Unani physicians since several decades. It possesses Muqawwi-i-A'sab (nervine tonic), Muharrik-i-A'sab (nervine stimulant) properties and is an effective treatment option for diseases like Laqwa (facial palsy), Falij (paralysis), Niqris (gout) and Waja'al-Mafasil (arthritis) etc. The aim of the study is to access and provide information of HAZ for its TLC, HPTLC Fingerprinting defining its clear qualitative perspective and acute oral toxicity evaluation for its safety assessment which was not done earlier, thus contributing in the field of research. Materials and Methods: The chief ingredient, nux-vomica was detoxified as per method mentioned in Unani Pharmacopeia before its use in formulation. TLC and HPTLC was developed under four detection system i.e., UV 366nm, UV 254nm, exposure to iodine vapours and after derivatization with anisaldehyde sulphuric acid. Acute toxicity studies were performed as per OECD Guidelines 425 at a limit dose of 2000 mg/kg. Observations were done for signs of toxicity, body weight, and feed consumption at regular intervals followed by haematological and biochemistry evaluation. Results: The generated data proved the authenticity and established the TLC and HPTLC profile of the formulation. Acute toxicity revealed no significant differences in HAZ-treated animals with respect to body weight gain, feed consumption, haematology, clinical biochemistry evaluation. No significant gross pathological observation was noticed in necropsy. Conclusion: Data of the present study is substantial and scientific proof of HAZ in terms of standardization and toxicity study that can be utilize in future research activities.

• Journal of Korea Entertainment Industry Association
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• v.15 no.3
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• pp.289-295
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• 2021

Today, the most important factor affecting the quality of human life is thought to be due to the environment. The importance of environmental monitoring systems to improve human life and improve welfare as the magnitude of the damage increases year by year due to the rapid increase in the frequency of hail, typhoons, collapse of incisions, landslides, etc. Is increasing day by day. Among environmental problems, problems caused by water quality have a very high proportion, and as there is a growing concern that the scale of damage will increase when water pollution accidents occur due to urbanization and industrialization, the demand for social water safety nets is increasing. have. In the last 5 years, 259 cases of water pollution (Han River 99, Nakdong River 31, Geum River 25, Seomjin River and Yeongsan River 19, and 85 others) have occurred in the four major river basins. Caused damage. Therefore, it is required to establish a water quality environment management strategy system based on big data that can minimize the uncertainty of the water quality environment by expanding the target of water quality management from the current water quality management system centered on the four major rivers to small and medium-sized rivers, tributaries/branches, and reservoirs. In this paper, we intend to construct and analyze a water quality monitoring system based on big data that can present useful water quality environment information by analyzing the water quality information accumulated for a long time.

• The Korean Society of Law and Medicine
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• v.22 no.3
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• pp.31-55
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• 2021

The Personal Information Protection Act, one of the revised 3 Data Laws, established a special cases concerning pseudonymous data. As a result, a personal information controller may process pseudonymized information without the consent of data subjects for statistical purposes, scientific research purposes, and archiving purposes in the public interest, etc. In addition, as a follow-up to the revised Personal Information Protection Act, a 'Guidelines for Utilization of Healthcare Data' was prepared, which deals with the pseudonymization in the medical sector. The guidelines are meaningful in that they provide practical criteria for accomplices by defining specific interpretations and examples that take into account the characteristics of healthcare data. However, the guidelines need to clarify the purpose of using pseudonymous data and strengthen the fairness of the composition of the data deliberation committee. The guidelines also require establishing a healthcare data compensation framework and strengthening the protection of rights for vulnerable subjects. In addition, the guidelines need to be adjusted for inconsistency with the Bioethics and Safety Act and the Medical Service Act. It is expected that this study will contribute to the creation of a safe environment for the utilization of healthcare data as well as the improvement of related laws and systems.

• Journal of Internet Computing and Services
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• v.23 no.5
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• pp.47-58
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• 2022

In recent years, navigation aids, which plays as sea traffic lights, have been digitized, and are developing beyond simple sign purpose to provide various functions such as marine information collection, supervision, control, etc. For example, Busan Port which is located in South Korea is leading the application of the advanced technologies by installing cameras on buoys and recording video images to supervise maritime accidents. However, there are difficulties to perform their major functions since the advanced technologies require long-term battery operation and also management and maintenance of them are hampered by marine characteristics. This study proposes a system that can automatically notify maritime objects passing around buoys by analyzing image information. In the existing sensor-based accident prevention systems, the alarms are generated by a collision detection sensor. The system can identify the cause of the accident whilst even though it is difficult not possible to fundamentally prevent the accidents. Therefore, in order to overcome these limitations, the proposed a maritime object detection system is based on marine characteristics. The experiments demonstrate that the proposed system shows about 5 times faster processing speed than other existing algorithms.

• Journal of People, Plants, and Environment
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• v.23 no.2
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• pp.211-220
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• 2020

The purpose of this study was to analyze the frequency and contents of horticultural activities in 696 individual activities listed in 11 teacher's guidebooks of Nuri Curriculum for 5-year-olds, and to find out the perceptions of horticultural activities in the formal curriculum. The target horticultural activities that were selected were those using natural objects like potted plants, water, wind, soil, stones, etc. as the topic or subject of activities, and those with different topics but are mentioning plants or natural objects as an example at least twice. The 150 selected horticultural activities were classified by life-based theme, activity type, activity domain, and medium. As a result of examining horticultural activities by life-based theme, there were 150 horticultural activities (21.55%): 40 in Spring, Summer, Autumn and Winter (5.75%), 34 in Animals, Plants, and Nature (4.89%), 22 in Environment and Life (3.16%), 19 in Our Country (2.73%), and nine in Our Neighborhood (1.29%), nine in Various Countries of the World (1.29%), four in Health and Safety (0.57%), four in Living tools (0.57%), four in Transportation (0.57%), three in Kindergarten and Friends (0.43%), two in Me and My Family (0.29%; χ²=130.427, p < .001). As a result of examining horticultural activities by activity type, there were 61 free choice activities (40.67%), 80 large and small group activities (53.33%), and nine outdoor play activities (6.00%), indicating that outdoor play was the fewest activity type (χ²=54.040, p < .001). The results of analyzing horticultural activities by activity domain showed that there were 25 in conversation (16.67%), 19 in science (12.50%), 14 in art (9.33%), 14 in cooking (9.33%), 10 in fairy tales (6.00%), nine in music (6.00%), eight in language (5.33%), eight in number operation (5.33%), eight in others (5.33%), six in children's plays (4.0%), six in games (4.0%), four in body and movement (2.67%), three in stacking (2.00%), three in roles (2.00%), three in rhythm (2.00%), two in children's poems (1.33%), two in field experience (1.33%) and one in outside play (0.67%; χ²=87.600, p < .001). As a result of examining the mediums used in the horticultural activities, 46 activities (30.67%) directly used plants as the mediums, 11 activities (7.33%) used soil such as stones, gravel, and earth as the mediums instead of plants, four activities (2.67%) used dry plants such as branches and dry leaves as the mediums, and 89 activities (59.33%) used videos, photos of plants, and pictures of plants as the mediums (χ²=121.307, p < .001).

• Journal of Life Science
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• v.31 no.12
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• pp.1128-1141
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• 2021

'Angelica' is one of the most traditionally consumed medicinal herbs around Northeast Asia including Korea for treatments of various diseases or health care purposes like hematopoiesis, blood circulation for women, sedative, analgesic, and a tonic medicine etc. Angelica gigas Nakai, a Korean native species of Angelica, is clearly different from the others in containing a high concentration of active ingredients like pyranocoumarines including decursin, decursinol, and decursinol angelate. These compounds have various kinds of positive effects such as anti-tumor activity including the precaution of neutropenia occurred during anticancer drug administration, improvements of metabolic disorders, menstrual irregularity, impairment of renal function, respiration improvement, cognition-enhancement, anti-inflammatory effect, anti-oxidative effect, enhancing fertility and so forth. Thus it implies incredible potentialities in future development for foods and drugs. However, certain purity-related qualities and/or overdose in food products can cause side effects like toxicities; therefore, their safety profiles should also be considered. This review focuses on the positive and negative effects of three pyranocoumarines in Angelica gigas Nakai and some possibilities and considerations for future food and drug products development.