• The Korean Journal of Pain
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• v.13 no.1
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• pp.60-66
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• 2000

Background: For terminal cancer pain management, controlled-release oral morphine (morphine sulfate tablet, MST) is a simple and convenient regimen. Recently, fentanyl transdermal therapeutic system (F-TTS, transdermal fentanyl) has been developed and became one of the alternative ways of providing adequate pain relief. This open prospective study was designed to compare the analgesic efficacy and safety of MST and transdermal fentanyl in the management of terminal cancer pain. Methods: In this open comparative and randomized study, 64 terminal cancer patients received one treatment for 15 days, controlled-release oral morphine (MST group) or fentanyl transdermal therapeutic system (F-TTS group). Daily diaries about the vital sign, visual analogue scale (VAS) for pain, opioids requirement, co-anagesics, adjuvant drugs and adverse effects were completed with 24 patients in MST group, 18 patients in F-TTS group. Results: The majority of patients in both treatment groups were late-stage cancer and their distribution was not different in both groups. Daily opioids requirement was 126.4 mg in MST uced in F-TTS group (P<0.05). The incidence of nausea, vomiting and constipation was lower in F-TTS group (P<0.05). Patients satisfaction was similar, but F-TTS patient group favored continous use of same treatment compared with MST group after the study was finished. Conclusions: Transdermal fentanyl seems to be safe and similar analgesic effect to controlled-release oral morphine for the control of the terminal cancer patients. However, transdermal fentanyl provides a simpler and more convenient especially in respect to constipation, nausea & vomiting. To determine the exact analgesic effect, cost-effectiveness and complications, controlled trials should be followed.

• The KIPS Transactions:PartC
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• v.17C no.6
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• pp.491-498
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• 2010

Wi-Fi based vehicle-to-infrastructure (V2I) communication is an emerging solution to improve the safety, traffic efficiency, and comfort of passengers. However, due to the high mobility of vehicles and the limited coverage of Wi-Fi APs, the V2I system may suffer from frequent handoffs although roadside APs can support cost effective Internet connectivity. Such problem of V2I systems can be overcome with Mobile AP (MAP) platform. The MAPs yield longer service duration by moving along with vehicles, yet they provide a lower link capacities than the roadside APs. In this paper, we propose a new association control mechanism that effectively determines whether the vehicle will select a fixed roadside-AP or a nearby MAP in mobile vehicular network environments. We consider both the achievable link bandwidth and available connection duration as a selection criterion and provide their run-time estimation method. Extensive simulation using real traces show significant performance improvements.

• The Korean Journal of Pesticide Science
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• v.12 no.4
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• pp.403-413
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• 2008

This study was conducted to select excellent tank mix combinations of pesticides for aerial application by manned helicopter. Among 209 pesticide combinations of 3-way tank-mixing for aerial application, a total of 93 recommendable combinations including tricyclazole SC+validamycin-A SL+imidacloprid SL were finally selected for the simultaneous control of key pests on paddy rice such as blast, sheath blight, brown planthopper and moth. The selected combinations were not phytotoxic to rice plants and nearby non-target crops, and excellent in physicochemical properties of ultra low volume (ULV) spray solutions. The efficacies on sheath blight, brown planthoppers and white-backed planthoppers of pesticides sprayed by aerial application were similar to those of pesticides by conventional spraying. Total cost of aerial application in paddy rice was very economical as one fourth level of that of conventional spraying.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.9
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• pp.208-214
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• 2014

Vehicle dynamic states used in various advanced driving safety systems are influenced by road geometry. Among the road geometry information, the vehicle pitch angle influenced by road slope and acceleration-deceleration is essential parameter used in pose estimation including the navigation system, advanced adaptive cruise control and others on sag road. Although the road slope data is essential parameter, the method measuring the parameter is not commercialized. The digital map including the road geometry data and high-precision DGPS system such as DGPS(Differential Global Positioning System) based RTK(Real-Time Kinematics) are used unusually. In this paper, low-cost cascade extended Kalman filter(CEKF) based road slope estimation method is proposed. It use cascade two EKFs. The EKFs use several measured vehicle states such as yaw rate, longitudinal acceleration, lateral acceleration and wheel speed of the rear tires and 3 D.O.F(Degree Of Freedom) vehicle dynamics model. The performance of proposed estimation algorithm is evaluated by simulation based on Carsim dynamics tool and T-car based experiment.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.8 no.6
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• pp.149-161
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• 2009

Electronic control systems of vehicle are rapidly developed to keep balance of a driver`s safety and the legal, social needs. The driver assistance systems are putted into practical use according to the cost drop in hardware and highly efficient sensor, etc. This study has developed a lane and vehicle detection program using CCD camera. The Risky Driving Analysis Program based on vision systems is developed by combining a risky driving detection algorithm formed in previous study with lane and vehicle detection program suggested in this study. Risky driving detection programs developed in this study with information coming from the vehicle moving data and lane data are useful in efficiently analyzing the cause and effect of risky driving behavior.

• Journal of IKEEE
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• v.22 no.2
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• pp.274-280
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• 2018

In this paper, we have developed the vacuum infusion automation system for the safety and quality advancement of the boat. It is necessary for the precise mixing rate of resinoid and curingagent to inject in an inner ship and deck at short time. We need for the optimal condition to a strengthen construction of boat. This one can solve the post deformability of the strengthen structure and can control the precise mixing rate of resinoid and curingagent to the resinoid fluidity and flowing rate per time. Under these condition, we can advance the an quality construction that based on the model and database information of the boat. Also, we can have an effective process management and retrench the production cost.

• Architectural research
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• v.13 no.3
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• pp.31-40
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• 2011

Profit-keeping behaviors naturally occur in the market to satisfy consumers, and the logic behind it lies in the economies of scale. On the flip side, some commodities transacted in the market are not available or can not be easily acquired unless the demand is high enough. Under this proposition, some consumers rise and find their own solution to meet the services at a reasonable cost or at an adequate level. The commonly adopted way is to establish a cooperative, and it stirs purchasing power by pooling resources and further bargains price and service quality. As a consumer cooperative, housing cooperatives notably found in rural towns enable the elderly to continue independent living. This study is to take a closer look at residential life of the rural elderly in housing cooperatives. Utilizing in-depth focus group interviews with 40 residents in four housing cooperatives, this qualitative research draws main factors affecting the decision to move in, residential assessment, and strengths and weakness of living in a housing cooperative. The primary factor influencing the moving decision is to continue to independent living in a familiar community, and the bottom line is planning ahead. Frailty and bereavement are found to be the leading occasions for them to move. The participants are satisfied with the independent living arrangement, and particularly, cited such features as safety and security, elderly-friendly design, common spaces, freedom, social activities and efficient living. Also, it is stated that some cooperative natures such as control over the property and giving a voice on management render positive impacts on the satisfaction with communal living. In spite of all the benefits and strengths, participants face with a public notion that an independent living arrangement like a housing cooperative has never done before in rural towns, so that most people recognize it as part of dependent living arrangements like nursing home.

• Proceedings of the KWS Conference
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• 2010.05a
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• pp.57-57
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• 2010

For thin panel welded structure, the various welding distortions were found due to the low resistance against welding deformation. Especially, buckling distortion induced in the thin panel welded structure produce severe problems related to cost in production stage and safety in service life. So, many researches including mechanical and thermal tensioning method for preventing the occurrence of buckling distortion in the production stage have been performed. The purpose of this study is to identify the behavior of longitudinal residual stress at the SA butt weldment with thin plate of 6mm thickness under tension load by 3 dimensional FEA. For it, mesh design for 3D FEA was constructed with 20 nodes brick element for butt weldment and 8 nodes shell element for base metal. According to FEA results, the longitudinal compressive strain inducing tensile residual stress at the butt weldment decreased. It was because the compressive thermal strain in way of weldment was reduced by tension load. The control effect of residual stress increased with an increase in tension load. So, if the amount of tension load applied to the weldment exceeds 1.5 times of longitudinal shrinkage force, the amount of longitudinal residual stress decreased below the critical value inducing the buckling distortion at the SA butt weldment. Its validity was verified by experiment.

• Korean Journal of Poultry Science
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• v.34 no.1
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• pp.77-83
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• 2007

Poultry products including meat and eggs constitute a major protein source in the American diet and disease-causing pathogens represent major challenges to the poultry industry. More than 95% of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper-virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

• Korean Journal of Poultry Science
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• v.31 no.1
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• pp.37-44
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• 2004

It has been recognized that the hen, like its mammalian counterparts, provides young chicks with antibodies as protection against hostile invaders. This system facilitates the transfer of specific antibodies from serum to egg yolk, and provides a supply of antibodies called immunoglobulin Y(IgY) to the developing embryo and the hatched chick. The protection against pathogens that the relatively immune-incompetent newly hatched chick has, is through transmission of antibodies from the mother via the egg. Egg yolk, therefore, can be loaded with a large amount of IgY against pathogens which can immobilize the existing or invading pathogens during the embryo development or in day-old chicks. Thus, the immunization of laying hens to various pathogens results in production of different antigen-specific IgY in eggs. Egg yolk contains 8∼20 mg of jmmunoglobulins (IgY) per ml or 136∼340 mg per yolk suggesting that more than 30 g of IgY can be obtained from one immunized hen in a year. By immunizing laying hens with antigens and collecting IgY from egg yolk, low cost antibodies at less than $10 per g compared to more than $20,000 per g of mammalian IgG can be obtained. This IgY technology opens new potential market applications in medicine, public health, veterinary medicine and food safety. A broader use of IgY technology could be applied as biological or diagnostic tool, nutraceutical or functional food development, oral-supplementation for prophylaxis, and as pathogen-specific antimicrobial agents for infectious disease control. This paper has emphasized that when IgY-loaded chicken eggs are produced and consumed, the specific antibody binds, immobilizes and consequently reduces or inhibits the growth or colony forming abilities of microbial pathogens. This concept could serve as an alternative agent to replace the use of antibiotics, since today, more and more antibiotics are less effective in the treatment of infections, due to the emergence of drug-resistant bacteria.