• Title/Summary/Keyword: safety benefits

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Safety Assessment of Bifidobacterium breve BB077 as Probiotics (프로바이오틱스 Bifidobacterium breve BB077 안전성 평가)

  • Woo, Jang-Bin;Han, Ji Yoon;Seo, Eunsol;Seo, MinYeong;Kim, Byung-Yong
    • Journal of Food Hygiene and Safety
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    • v.37 no.5
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    • pp.306-309
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    • 2022
  • Probiotics are live microorganisms that confer health benefits onto the host when administered at adequate doses. Most widely used probiotics, such as lactobacilli and bifidobacteria, are known to be elements of healthy gut microflora and hence are not considered a threat to the host. However, probiotics may pose a risk in certain populations with compromised immune systems or defects in gut barrier functions. Herein, we evaluated the safety of Bifidobacterium breve BB077, according to the safety evaluation guidelines for probiotics produced by the National Institute of Food and Drug Safety Evaluation (NIFDS). The results show that B. breve BB077 is both non-hemolytic and non-cytolytic. In contrast, B. breve BB077 exhibited higher streptomycin and tetracycline resistance than the suggested NIFDS standard cut-off values. Hence, a genetic analysis of the streptomycin and tetracycline resistance genes was performed to determine the origin of antimicrobial resistance. Streptomycin and tetracycline resistance was shown have arisen from chromosomal mutations and considered intrinsic to the taxonomic group. In conclusion, the B. breve BB077 strain might be safe for human consumption.

Multiple-end-point Bioassays Using Microorganisms

  • Iwahashi, Hitoshi
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.5 no.6
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    • pp.400-406
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    • 2000
  • Since the 1950s, the numbers of species and chemicals produced have significantly increased. Despite the fact that industrial chemicals have given us numerous benefits, there is no doubt that they have damaged the environment. The chemicals being dispersed on the earth should be carefully controlled to prevent adverse effects. Bioassay is one of the methods to assess chemical safety. In bioassay systems, chemical safety is estimated by monitoring biological responses to environmental pollutants and newly synthesized chemicals. This report introduces multiple-point bioassay systems that are based on chemical sensitivities of microorganisms, responses of one kind of organism, and micro-array technology. Multiple-end-point bioassays enable the prediction of chemicals in the environment and the understanding of toxicities of newly synthesized chemicals.

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Comparative Economic Analysis on SOx Scrubber Operation for ECA Sailing Vessel

  • Jee, Jae-hoon
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.3
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    • pp.262-268
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    • 2020
  • The IMO (International Maritime Organization) has mandated the restriction of SOx emissions to 0.5 % for all international sailing vessels since January 2020. And, a number of countries have designated emission control areas for stricter environmental regulations. Three representative methods have been suggested to cope with these regulations; using low-sulphur oil, installing a scrubber, or using LNG (Liquefied Natural Gas) as fuel. In this paper, economic analysis was performed by comparing the method of installing a scrubber with the method of using low-sulphur oil without installing additional equipment. We suggested plausible layouts and compared the pros and cons of dif erent scrubber types for retrofitting. We selected an international sailing ship as the target vessel and estimated payback time and benefits based on navigation route, fuel consumption, and installation and operation costs. Two case of oil prices were analyzed considering the uncertainty of fuel oil price fluctuation. We found that the expected payback time of investment varies from 1 year to 3.5 years depending on the operation ratio of emission control areas and the fuel oil price change.

Vehicle Cruise Control with a Multi-model Multi-target Tracking Algorithm (복합모델 다차량 추종 기법을 이용한 차량 주행 제어)

  • Moon, Il-Ki;Yi, Kyong-Su
    • Proceedings of the KSME Conference
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    • 2004.11a
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    • pp.696-701
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    • 2004
  • A vehicle cruise control algorithm using an Interacting Multiple Model (IMM)-based Multi-Target Tracking (MTT) method has been presented in this paper. The vehicle cruise control algorithm consists of three parts; track estimator using IMM-Probabilistic Data Association Filter (PDAF), a primary target vehicle determination algorithm and a single-target adaptive cruise control algorithm. Three motion models; uniform motion, lane-change motion and acceleration motion, have been adopted to distinguish large lateral motions from longitudinal motions. The models have been validated using simulated and experimental data. The improvement in the state estimation performance when using three models is verified in target tracking simulations. The performance and safety benefits of a multi-model-based MTT-ACC system is investigated via simulations using real driving radar sensor data. These simulations show system response that is more realistic and reflective of actual human driving behavior.

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A Qualitative Study on the Consumption Value of Preschooler Clothing by Mothers (취학 전 자녀에 대한 부모의 유아복 소비가치에 관한 질적 연구)

  • Rhee, Young Ju;Lee, Joo Yun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.10
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    • pp.1100-1116
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    • 2012
  • Due to the growth of the preschooler clothing industry, significant research has been conducted on the pursued benefits, purchase behavior, and purchase intension related to preschooler clothing; however, reports on the consumption value of preschooler clothing remain limited. This study provides a consumption value for preschooler clothing through qualitative research. A total of 15 mothers of preschoolers aged 1-6 years old were interviewed on the consumption value of preschooler clothing. The subsequent consumption value of preschooler clothing consisted of 9 major factors (vicarious satisfaction value, social display/image value, safety value, convenient value, economic value, distinguishable value, expressive-aesthetic value, fashionable value and conditional value). In addition, the vicarious satisfaction value, social display/image value, safety value, and convenient value were new-expressed values that differed from previous reports on the consumption value of adult clothing.

Implementation of Background Scene in the Virtual Reality Ship Simulator (가상현실 선박 시뮬레이터의 배경 구현)

  • 임정빈
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.6 no.1
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    • pp.11-22
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    • 2000
  • The paper describes creation methods of background scenes to implement realistic virtual environments in the VRSS (Virtual Reality Ship Simulator). VRSS is next-generation system constructed with virtual tools in a virtual space. Thus, it could have many benefits compared to conventional ship simulators composed with heavy bridge mock-up system and wide visual presentations. In this work, we developed effective 3D object modeling techniques, and constructed virtual harbor scene by using 3D-Webmaster authoring tool. The virtual harbor was built with object-oriented 3D objects modeled to interact with user's action. With the immersion-type VR system, we created virtual harbor environments in a virtual space, and discussed on the naturalness of the scene with test results of SDMPA (Semantic Differential Method for Psychophysical Assessment) by 10 subjects. As the results of subject assessment, all of the participants could felt natural-like harbor. Therefore, we found that the proposed creation methods and procedures of background scene are enabling to fit to the full mission VRSS construction.

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Isolation of Weissella strains as potent probiotics to improve antioxidant activity of salted squid by fermentation

  • Le, Bao;Yang, Seung Hwan
    • Journal of Applied Biological Chemistry
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    • v.61 no.1
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    • pp.93-100
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    • 2018
  • The aim of this study was to enhance the antioxidant activity of salted squid by inoculation of two Weissella spp. strains (W. cibaria FB-069 and W. viridescens FB-077) isolated from traditional Korea salted squid. The safety and probiotic potential characteristics of these two strains were evaluated. The safety of these strains was analyzed based on hemolytic activity, mucin degradation, biogenic amino production, and resistance to antibiotics. These lactic acid bacteria showed probiotic potential, including resistance to gastrointestinal tract conditions, adhesion to Caco-2 cells, and aggregation. The low-salted squid fermented with Weissella strains had consistently higher antioxidant activity through changing their amino acid profiles. Therefore, W. cibaria FB-069 and W. viridescens FB-077 might be good candidates for fermentation of salted squid to develop functional food with enhanced health benefits.

Analysis of the Consumers' Awareness and Information Need for Food Safety -Focused on irradiated foods and environmental hormones- (소비자의 식품 안전성에 대한 인지도 및 정보요구도에 관한 분석 -방사선조사 식품과 환경호르몬을 중심으로-)

  • Kim, Hyo-Chung;Kim, Mee-Ra
    • Journal of the Korean Society of Food Culture
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    • v.17 no.2
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    • pp.153-164
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    • 2002
  • This study examined the consumers' awareness and information need toward the irradiated foods and environmental hormones. The data were collected from 350 adults living in Daegu and Busan by the self-administered questionnaire. Frequencies and chi-square tests were conducted by SPSS. The results of the survey were as follows: (1) consumers' awareness regarding the irradiated foods and environmental hormones were low, while consumers' concerns for them were high, (2) the orders of the information needs for the irradiated foods are safety of irradiated foods, dose permitted for food irradiation, benefits of irradiated foods, kinds of permitted irradiated foods, and legislations of food irradiation, and (3) the orders of the information needs for the environmental hormones are harmfulness of environmental hormones, standards for contamination by environmental hormones, materials releasing environmental hormones, methods to prevent environmental hormones, and kinds of environmental hormones.

Study on the Application of RAMS for Rolling Stock (철도차량 RAMS 적용에 관한 연구)

  • Oh, Ji-Eun;Kang, Chan-Yong;Kim, Chul-Ho
    • Proceedings of the KSR Conference
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    • 2004.06a
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    • pp.206-212
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    • 2004
  • This paper is application of System Assurance(SA) for the rolling stock. As railway systems become more complex, design teams are increasingly under pressure to deliver, design solutions, which integrate both technical and Systems Assurance(SA). Systems Assurance is the application of management methods and analysis techniques to ensure that a design meets Reliability, Availability, Maintainability and Safety (RAMS) criteria. It should be clearly understood that the intent of System Assurance is not just to provide analytical techniques as a metric on performance, but more importantly it should provide a management tool with which to co-ordinate and assure the whole design. System Assurance encompasses the ongoing requirement to consider safety, and RAM through each stage of a Project, from feasibility study through to commissioning and operation. If System Assurance is undertaken properly at feasibility study at the design stages of a Project, the benefits of such analyses can be significant in identifying potential problems early enough for action to be taken before manufacture or installation. At commissioning, RAMS demonstration activities are undertaken to validate the predictive and analytical techniques undertaken during the design.

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A Multi-target Tracking Algorithm for Application to Adaptive Cruise Control

  • Moon Il-ki;Yi Kyongsu;Cavency Derek;Hedrick J. Karl
    • Journal of Mechanical Science and Technology
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    • v.19 no.9
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    • pp.1742-1752
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    • 2005
  • This paper presents a Multiple Target Tracking (MTT) Adaptive Cruise Control (ACC) system which consists of three parts; a multi-model-based multi-target state estimator, a primary vehicular target determination algorithm, and a single-target adaptive cruise control algorithm. Three motion models, which are validated using simulated and experimental data, are adopted to distinguish large lateral motions from longitudinally excited motions. The improvement in the state estimation performance when using three models is verified in target tracking simulations. However, the performance and safety benefits of a multi-model-based MTT-ACC system is investigated via simulations using real driving radar sensor data. The MTT-ACC system is tested under lane changing situations to examine how much the system performance is improved when multiple models are incorporated. Simulation results show system response that is more realistic and reflective of actual human driving behavior.