• Mass Spectrometry Letters
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• v.13 no.3
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• pp.58-83
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• 2022

We developed analytical methods using high performance chromatography (HPLC) and liquid chromatography tandem mass spectrometry (LC-MS/MS) for the simultaneous determination of 80 unapproved compounds in dietary supplements. The target compounds for analysis were unapproved ingredients (e.g., pharmaceuticals) that have potential adverse effects on consumers owing to accidental misuse, overuse, and interaction with other medication in dietary supplement. Two analytical methods were tested to identify the optimal validation results according to AOAC guideline. As a result, limit of quantification (LOQ) was 0.14-0.5 ㎍ mL^-1; linearity (r²) was ≥ 0.99; accuracy (expressed as recovery) was 78.9-114%; precision (relative standard deviation) was ≤ 4.28% in the HPLC method. In the LC-MS/MS method, LOQ was 0.01-2 ng mL^-1, linearity (r²) was ≥0.98, accuracy was 71.7-119%; precision was ≤ 12.5%. The developed methods were applied to 51 dietary supplements collected from 2019 to 2021 through MFDS alert system. Based on our previous monitoring study, major compounds were icariin, sibutramine, yohimbine, sildenafil, tadalafil, sennosides (A, B), cascarosides (A, B, C, D), and phenolphthalein. In this study, we re-analyzed samples of detected compounds, and evaluated the statistical difference using Bland-Altman analysis to compare two analytical approaches between HPLC and LC-MS/MS. These results showed a good agreement between two methods that can be used to monitor the unapproved ingredients in dietary supplements. The developed two methods are complementarily suitable for monitoring the adulteration of 80 unapproved compounds in dietary supplements.

• Journal of the Korean Society of Safety
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• v.18 no.4
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• pp.51-56
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• 2003

The goal of this study is to show the way to decrease the noise from air nozzles. The variables of this test are the shapes of air nozzles, air flow rate and the distance between a reflection plate and a nozzle tip. This experiment is aimed to find the most appropriate condition to minimize the noise. These are the results. If diameter ratio is more than 12:8, noise level increases by over 10 dB(A) regradless of the distance between a reflection plate and a nozzle and the existence of a reflection plate. And when $L_2$ of a nozzle is 5mm long, noise level rise relatively highly. So, it is strongly recommended that $L_2$ should be manufactured more than 10mm. The reason for a high intensity noise is that when diameter ratio is more than 12:8, the diameter of a nozzle tip($D_2$) turns small drastically, which increases the air velocity. It is assumed that when the vortes is great around the spots where a nozzle hole is suddenly smaller, great turbulent flow increases much noise.

• Nuclear Engineering and Technology
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• v.46 no.4
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• pp.513-520
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• 2014

In this paper, three types of operational and industrial absorbers used at research reactors, including Ag-In-Cd alloy, $B_4C$, and Hf are selected for sensitivity analyses. Their integral effects on the main neutronic core parameters important to safety issues are investigated. These parameters are core excess reactivity, shutdown margin, total reactivity worth of control rods, thermal neutron flux, power density distribution, and Power Peaking Factor (PPF). The IAEA 10 MW benchmark core is selected as the case study to verify calculations. A two-dimensional, three-group diffusion model is selected for core calculations. The well-known WIMS-D4 and CITATION reactor codes are used to carry out these calculations. It is found that the largest shutdown margin is gained using the $B_4C$; also the lowest PPF is gained using the Ag-In-Cd alloy. The maximum point power densities belong to the inside fuel regions surrounding the central flux trap (irradiation position), surrounded by control fuel elements, and the peripheral fuel elements beside the graphite reflectors. The greatest and least fluctuation of the point power densities are gained by using $B_4C$ and Ag-In-Cd alloy, respectively.

• Journal of the Korean Chemical Society
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• v.44 no.2
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• pp.102-108
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• 2000

Relative retention times (RRTs) of RAH molecules in HPLC are trained and predicted intesting sets using a multiple linear regression (NLR) and an artificial neural network (ANN). The maindescriptors in QSRR are molecular connectivity ($^1X_v,\;^2X_v$), the length-to-breadth ratios (L/B), and molecular dipole moment(D). L/B which is related with slot model is a good descripter in ANN, but isn't in MLR. Varainces which show the accuracy of prediction times in testing sets are 0.0099, 0.0114 for ANN and MLR, respectively. It was shown that ANN can exceed the MLR in prediction accuracy.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2013.05a
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• pp.1047-1048
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• 2013

• Proceedings of the Korean Institute of Industrial Safety Conference
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• 2002.11a
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• pp.86-89
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• 2002

"바람직하지 않은 소리", "불쾌한 소리"로 총칭되는 소음은 현대산업에서 만들어지는 많은 환경적 오염물질(오염원)중의 예이다. 전체 인구의 60%이상은 매일 소음환경에 노출되고 있으며 도시 내 소음도는 10년마다 배로 증가하는 추세이다. 도시지역 신경질환의 70%는 소음이 그 원인이며, 각종 피해증상(수면부족, 두통, 불쾌감, 불안감, 소화불량, 신경질 등)의 호소가 급증하고 있다. 공항지역(86~91dB) 주민의 50%가 불쾌감이나 정서적 불안을 느끼는 것도 소음에서 기인한다.(중략)끼는 것도 소음에서 기인한다.(중략)

• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 2007.11a
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• pp.126-129
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• 2007

• Journal of Korean Society of Disaster and Security
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• v.16 no.4
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• pp.9-18
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• 2023

Climate change affects the safety of river revetments, especially those associated with external flooding. Research on slope reinforcement has been actively conducted to enhance revetment safety. Recently, technologies for producing embankment blocks using recycled materials have been developed. However, it is essential to analyze the impact of block shapes on the flow characteristics of exclusion zones for revetment safety. Therefore, this study investigates the influence of revetment block shapes on the hydraulic characteristics of revetment surfaces through 3D numerical simulations. Three block shapes were proposed, and numerical analyses were performed by installing the blocks in an idealized river channel. FLOW-3D was used for the 3D numerical simulations, and the variations in maximum flow velocity, bed velocity beneath the revetment, and maximum shear stress were analyzed based on the shapes of the revetment blocks. The results indicate that for irregularly sized and spaced revetment blocks, such as the natural stone-type vegetation block (Block A), when connected to the revetment in an irregular manner, the changes in flow velocity in the revetment installation zone are more significant than those for Blocks B and C. It is anticipated that considering the topographical characteristics of rivers in the future will enable the design of revetment blocks with practical applicability in the field.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.48 no.3
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• pp.13-20
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• 2011

In this paper, we proposed a system to raise gas safety management by using the wireless communication module and intelligent gas safety appliances. Our designed systems configure a micom-gas meter, an automatic extinguisher, sensors, and a wallpad. A micom-gas-meter monitors gas flow, gas pressure, and earthquake. An automatic fire extinguisher checks gas(combustible) leaks and temperature of $100^{\circ}C$ and $130^{\circ}C$. Sensors measure smoke and CO gas. In our novel system, a micom-gas meter cut off inner valve with warnings, an automatic fire extinguisher cut off middle valve and spray extinguishing materials, and sensors generate signals for smoke and CO when occurring gas risk. Gas safety appliances and sensors takes safety measures, and transmit those signal to a wallpad. The wallpad again transmit signal like events to a control server. Users can connect web pages for gas safety through B-ISDN and control and manage them. We hereby devised scenarios for gas safety and risk management, and demonstrated their effectiveness through experiments.

• Safety and Health at Work
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• v.10 no.2
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• pp.229-236
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• 2019

Background: Emerging reports suggest the potential for adverse health effects from exposure to emissions from some additive manufacturing (AM) processes. There is a paucity of real-world data on emissions from AM machines in industrial workplaces and personal exposures among AM operators. Methods: Airborne particle and organic chemical emissions and personal exposures were characterized using real-time and time-integrated sampling techniques in four manufacturing facilities using industrial-scale material extrusion and material jetting AM processes. Results: Using a condensation nuclei counter, number-based particle emission rates (ERs) (number/min) from material extrusion AM machines ranged from $4.1{\times}10^{10}$ (Ultem filament) to $2.2{\times}10^{11}$ [acrylonitrile butadiene styrene and polycarbonate filaments). For these same machines, total volatile organic compound ERs (${\mu}g/min$) ranged from $1.9{\times}10^4$ (acrylonitrile butadiene styrene and polycarbonate) to $9.4{\times}10^4$ (Ultem). For the material jetting machines, the number-based particle ER was higher when the lid was open ($2.3{\times}10^{10}number/min$) than when the lid was closed ($1.5-5.5{\times}10^9number/min$); total volatile organic compound ERs were similar regardless of the lid position. Low levels of acetone, benzene, toluene, and m,p-xylene were common to both AM processes. Carbonyl compounds were detected; however, none were specifically attributed to the AM processes. Personal exposures to metals (aluminum and iron) and eight volatile organic compounds were all below National Institute for Occupational Safety and Health (NIOSH)-recommended exposure levels. Conclusion: Industrial-scale AM machines using thermoplastics and resins released particles and organic vapors into workplace air. More research is needed to understand factors influencing real-world industrial-scale AM process emissions and exposures.