• The Korean Journal of Pain
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• v.21 no.3
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• pp.237-240
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• 2008

Ramsay Hunt syndrome is a disorder characterized by herpetic eruptions on the auricle, facial paralysis, and vestibulocochlear dysfunction, and is attributed to varicella zoster virus infection in the geniculate ganglion. Ramsay Hunt syndrome accounts for about 10% cases of facial palsy. We report a 46-year-old healthy man developed left side skin vesicles on the face with severe pain. We thought of the trigeminal herpes zoster. He was treated with intravenous acyclovir, and stellate ganglion block daily. Four days later, brain magnetic resonance imaging revealed small areas of enhancement in the seventh cranial nerve and eighth cranial nerve, not in the fifth cranial nerve. Eight days later, the left facial palsy was come. We confirmed him as Ramsay Hunt syndrome. We started steroid therapy immediately. He recovered completely a month later. The patient was improved through the early antiviral therapy, steroid medication and stellate ganglion block.

• Clinical and Experimental Pediatrics
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• v.58 no.4
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• pp.148-153
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• 2015

The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium resorption in kidney. They can also cause a type 5 Bartter syndrome by inhibiting the apical potassium channel in the thick ascending limb of the loop of Henle in the kidney. This study presents a patient who had autosomal dominant hypocalcemia with Bartter syndrome due to an activating mutation Y829C in the transmembrane domain of the CaSR. Symptoms of hypocalcemia occurred 12 days after birth and medication was started immediately. Medullary nephrocalcinosis and basal ganglia calcification were found at 7 years old and at 17 years old. Three hypercalcemic episodes occurred, one at 14 years old and two at 17 years old. The Bartter syndrome was not severe while the serum calcium concentration was controlled, but during hypercalcemic periods, the symptoms of Bartter syndrome were aggravated.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.19 no.1
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• pp.55-63
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• 2015

Objectives In order to the review of the Yoon Gil-Young's theory on the "differentiation of syndromes", we studied on the his method and system of classification on the "differentiation of syndromes". Methods We reviewed on "The Clinical Formula Science Traditional Korean Medicine 東醫臨床方劑學", "A study on the Methodology of Traditional Korean Medicine 東醫學의 方法論硏究" "The theory of SaSang Constitution Medicine 四象體質醫學論". From a connected standpoint with the basic theory and clinical medicine, considered on the Yoon Gil-Young's theory of "differentiation of syndromes". Results Yoon Gil-Young's theory of differentiation of syndromes and treatment was widespread so much that he studied on the learning field of Traditional Korean Mediciine and ingenious as well. The main principles of differentiation of syndromes was summarized the three representative syndrome-complexes; BON-HER(original deficiency syndrome), BON-HAN(orginal cold excess syndrome), BON-YEOL(original heat excess syndrome). And also the three representative syndrome-complexes was previously carried out the details of differentiation of syndromes and assigned represent prescription one by one. Conclusions As the results, Yoon Gil-Young insisted the system of differentiation of syndromes closely connecting with Traditional Korean Medical physiology, pathology, diagnosis and prescriptions. And therefore he was a frontier of the field of Traditional Korean Medicine.

• Journal of Acupuncture Research
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• v.35 no.1
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• pp.4-10
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• 2018

The aim of this report was to show the effects of acupotomy in patients with carpal tunnel syndrome. Four patients were treated with acupotomy twice. Visual analogue scale (VAS), Tinel's sign, Phalen's test, Boston carpal tunnel syndrome questionnaire (BCTQ), muscular strength test, and a cross-sectional area of median nerve was measured using ultrasound before and after treatment. In all 4 cases, the VAS score, BCTQ score and cross-sectional area of median nerve, all decreased and muscular strength test score increased. Tinel's sign and the Phalen's test changed from a positive to a negative in most cases. This report shows that acupotomy is an effective treatment for carpal tunnel syndrome. Further larger are needed to fully evaluate the beneficial effects of this treatment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.4
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• pp.108-116
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• 2018

Objectives : A Report on the Improvement of korean medical treatment of Secondary Raynaud's Syndrome Caused by Systemic Sclerosis. Methods : We treated a Secondary Raynaud's syndrome 59-year-old woman with herbal medicine and acupuncture treatment for 3 months. The evaluation of treatment was confirmed by photographs before and after treatment, VAS, and palm skin temperature. Results : After treatment, the color of both fingernails and finger skins recovered from white to purplish red, and Raynaud phenomenon and palm flaring were decreased. VAS decreased from 8 to 2 and palm skin temperature increased by left hand 1.4 degrees right hand 1.2 degrees. Conclusions : It was shown that korean medical treatment was effective in the conservative treatment of Secondary Raynaud's syndrome caused by systemic sclerosis.

• Journal of Yeungnam Medical Science
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• v.30 no.1
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• pp.55-57
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• 2013

Synovitis acne pustulosis hyperostosis osteitis (SAPHO) syndrome is a rare disease that involves the skin, bones and joints. It is thought to be caused by infection with low-toxicity bacteria and to be the result of reactive infectious osteitis. However, this hypothesis has not yet been clearly established. New SAPHO syndrome treatment methods are needed because the disease does not respond to treatment in many cases. In this paper, a case is reported of SAPHO syndrome with pain in the acromioclavicular joint and with squamous and pustular macules on the palms and soles. First, the patient was treated with aceclofenac, prednisolon and sulfasalazine for two weeks. However, the symptoms were not relieved, so methotrexate and pamidronate were added to the treatment. Since no improvement was seen after four weeks of treatment, adalimumab was prescribed. The skin lesions were relieved two weeks later, and the bone pain and arthralgia, four weeks later. No recurrence or adverse effects were observed at the 22-week follow-up.

• Journal of Genetic Medicine
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• v.15 no.1
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• pp.38-42
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• 2018

WAGR (Wilms tumor, aniridia, genitourinary anomalies, and mental retardation) syndrome is a rare contiguous gene deletion syndrome caused by deleting genes including WT1 and PAX6 genes in 11p13 region, which is characterized by Wilms tumor, aniridia, genitourinary abnormalities, and intellectual disability. We report the clinical and cytogenetic characteristics of one Korean patient with WAGR syndrome. The patient shows bilateral sporadic aniridia and genital anomalies at 2 months of age. A heterozygous 14.5 Mb interstitial deletion of 11p14.3p12 region was detected by array comparative genomic hybridization. At 2 years and 10 months of age, Wilms tumor is found through regularly abdominal ultrasonography and treated by chemotherapy, radiation therapy and surgery.

• The Journal of Korean Medicine
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• v.37 no.2
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• pp.125-132
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• 2016

Objectives: The purpose of this study is to evaluate the clinical effects of Embedding Therapy for Ramsay Hunt syndrome. Methods: 5 patients with Ramsay Hunt syndrome were treated with Embedding therapy. It was performed once a day, once a week. 15~20 Embedding threads were used in each Embedding treatment. The total number of Embedding therapy treatments was 4 or 8. To evaluate the effects of Embedding therapy, we analyzed Yanagihara's score and House-Brackmann scale Results: In case 1, After treatment the Yanagihara's score was changed from 3 to 7 and the House-Brackmann scale was changed from VI to V. In case 2, After treatment the Yanagihara's score was changed from 12 to 33 and the House-Brackmann scale was changed from IV to I. In case 3, After treatment the Yanagihara's score was changed from 3 to 9 and the House-Brackmann scale was changed from VI to V. In case 4, After treatment the Yanagihara's score was changed from 22 to 32 and the House-Brackmann scale was changed from III to I. In case 5, After treatment the Yanagihara's score was changed from 23 to 37 and the House-Brackmann scale was changed from III to I. Conclusion: Embedding Therapy is effective for improve the symptoms of Ramsay Hunt syndrom. Therefore, it will be used to treat Ramsay Hunt syndrome.

• Journal of Genetic Medicine
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• v.11 no.2
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• pp.79-82
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• 2014

Mowat-Wilson syndrome is an extremely rare genetic disease that is characterized by intellectual disability, facial dysmorphism, Hirschsprung's disease, and other congenital anomalies. This disorder is caused by heterozygous mutations or deletions in the zinc finger E-box-binding homeobox-2 gene (ZEB2). Thus far, approximately 200 cases of Mowat-Wilson syndrome have been reported worldwide. In Korea, only one case with a 2q22 deletion, which also affects ZEB2, has been previously reported. Here, we describe a patient with Mowat-Wilson syndrome who presented with developmental delays, typical facial dysmorphism, and Hirschsprung's disease. Molecular analysis of ZEB2 identified a novel heterozygous mutation at c.190dup ($p.S64Kfs^*6$). To our knowledge, this is the second report of a Korean patient with Mowat-Wilson syndrome that has been confirmed genetically.

• Journal of Korean Dental Science
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• v.4 no.1
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• pp.33-37
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• 2011

Gorlin-Goltz syndrome is an autosomal dominant disorder with a high degree of penetrance. It is characterized by basal cell carcinomas, odontogenic keratocysts, palmar and plantar pits and ectopic calcifications of falx cerebri. The presence of two major and one minor criteria or one major and three minor criteria are necessary to establish a diagnosis. Early diagnosis and treatment of Gorlin-Goltz syndrome, as well as family screening and genetic counseling are essential as it may be associated in 10% of patients with aggressive basal cell carcinoma and malignant neoplasias. We report here a patient with Gorlin-Goltz syndrome.