• The Journal of the Convergence on Culture Technology
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• v.9 no.2
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• pp.1-8
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• 2023

This study was a descriptive survey study to confirm the correlation between self-differentiation, Nursing Professionalism, and care efficacy in nursing college students, and to confirm the mediating effect of Nursing Professionalism in the relationship between self-differentiation and care efficacy. The data collection period is from October 30 to November 30, 2022. Data analysis was performed using t-test, Pearson's correlation, and regression methods. Studies have shown that the general characteristics that show significant differences in care efficacy were grade level and major satisfaction. The three variables were statically correlated. In the relationship between self-differentiation and care efficacy, Nursing Professionalism appeared to be a partial mediator (Z=2.196, p<0.05). The partial mediated effect explanatory power was 40%. This study was significant in that it examines the partial mediating effect of Nursing Professionalism in the relationship between self-differentiation and care efficacy for nursing college students, and has prepared the basic data for improving the care efficacy of nursing college students in the future. In the follow-up study, it would be created a program to improve the efficacy of care based on the results of this study and propose an analysis study of its effectiveness. It also proposes a study to expand the number of subjects to identify factors that can affect the efficacy of care.

• Anatomy and Cell Biology
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• v.56 no.4
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• pp.508-517
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• 2023

In cancer patients, chemo/radio therapy may cause infertility by damaging the spermatogenesis affecting the self-renewal and differentiation of spermatogonial stem cells (SSCs). In vitro differentiation of stem cells especially mesenchymal stem cells (MSCs) into germ cells has recently been proposed as a new strategy for infertility treatment. The aim of this study was to evaluate the proliferation and differentiation of SSCs using their co-culture with Sertoli cells and conditioned medium (CM) from adipose tissue-derived MSCs (AD-MSCs). Testicular tissues were separated from 2-7 days old neonate Wistar Rats and after mechanical and enzymatic digestion, the SSCs and Sertoli cells were isolated and cultured in Dulbecco's modified eagle medium with 10% fetal bovine serum, 1X antibiotic, basic fibroblast growth factor, and glial cell line-derived neurotrophic factor. The cells were treated with the CM from AD-MSCs for 12 days and then the expression level of differentiation-related genes were measured. Also, the expression level of two major spermatogenic markers of DAZL and DDX4 was calculated. Scp3, Dazl, and Prm1 were significantly increased after treatment compared to the control group, whereas no significant difference was observed in Stra8 expression. The immunocytochemistry images showed that DAZL and DDX4 were positive in experimental group comparing with control. Also, western blotting revealed that both DAZL and DDX4 had higher expression in the treated group than the control group, however, no significant difference was observed. In this study, we concluded that the CM obtained from AD-MSCs can be considered as a suitable biological material to induce the differentiation in SSCs.

• (The)Study of the Eastern Classic
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• no.49
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• pp.393-430
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• 2012

In this paper, Bowen's family therapy from the perspective of the theory, narrative analysis of Korean novels, three Regis - tration Subsection.Bowen's description of the individual's behavior is causing problems within the family of anxiety and self-differentiation using two variables. The home if problems or conflicts expressed in these works, the figures showed that the undifferentiated ego at the center of the problem. Undifferentiated ego character felt extreme anxiety when their alienation from the relationship of the family-oriented jeokjangja Undifferentiated ego to relieve anxiety and to consolidate their position in the family relationship, so people were strongly united with each other. Sohyunseongnok, Chossisamdaerok series structures and patterns of a series of domestic problems occur, "mother and son, self-differentiation self undifferentiated undifferentiated ego and self-differentiation mother son, mother and self-ego undifferentiated undifferentiatedcan be subdivided into the son '.Established a symbiotic relationship between them and the U.S. established the presence of a pattern, healer, depending on the deployment method depends narrative. And is divided accordingly, self-determination and to the Son, a son, a son to be born again through repentance of the execution. Depending on the presence or absence healer than what was described on the deployment structure differs. Undifferentiated ego and self undifferentiated mother son family therapist within the family, the problem is solved. Son, a son to repent and be born again, and that caused the problem. Ego Undifferentiated mother and son self-differentiation, undifferentiated ego and self-differentiation mother son home my healer in the absence son committed suicide and executions each tragedy occurred. Personal level, but occurred at home conflicts or problems about this when analyzing the Three-generation stories of the Joseon Dynasty, by applying the theory of Bowen's Family Therapy view dimension in the relationship between family were. Toughness or desire of any one individual, but serious conflicts and problems within the family, the institution of the family itself is the root cause was. And was able to reveal aspects of narrative flow, depending on the presence or absence of family therapists vary significantly depending on his role in the rest of the family comfort and peace determines whether the Three-generation stories of the Joseon Dynasty, received an important narrative of men and axis formation. In a gauze-like situation of this problem in the Three-generation stories of the Joseon Dynasty, a personal desire or toughness in confined without the dimension of the entire family. And extrinsic psychological approach against the background of the wall in the main narrative of the sufferings of women of Korean novels, approached significance.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.4
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• pp.588-595
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• 2013

Mesenchymal stem cells (MSCs) are often known to have a therapeutic potential in the cell-mediated repair for fatal or incurable diseases. In this study, canine umbilical cord MSCs (cUC-MSCs) were isolated from umbilical cord matrix (n = 3) and subjected to proliferative culture for 5 consecutive passages. The cells at each passage were characterized for multipotent MSC properties such as proliferation kinetics, expression patterns of MSC surface markers and self-renewal associated markers, and chondrogenic differentiation. In results, the proliferation of the cells as determined by the cumulative population doubling level was observed at its peak on passage 3 and stopped after passage 5, whereas cell doubling time dramatically increased after passage 4. Expression of MSC surface markers (CD44, CD54, CD61, CD80, CD90 and Flk-1), molecule (HMGA2) and pluripotent markers (sox2, nanog) associated with self-renewal was negatively correlated with the number of passages. However, MSC surface marker (CD105) and pluripotent marker (Oct3/4) decreased with increasing the number of subpassage. cUC-MSCs at passage 1 to 5 underwent chondrogenesis under specific culture conditions, but percentage of chondrogenic differentiation decreased with increasing the number of subpassage. Collectively, the present study suggested that sequential subpassage could affect multipotent properties of cUC-MSCs and needs to be addressed before clinical applications.

• The Korean Journal of Community Living Science
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• v.14 no.1
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• pp.1-12
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• 2003

The purpose of this study was to investigate the maternal parenting stress and related variables through early childhood in rural areas (Iksan and Kimpo). The subject were 134 mothers who have less than 5-year old children. The statistics used for this data were freguency, percentile, t-test, ANOVA, and multiple regression analysis. The main results obtained from this study were as follows. The degree of maternal parenting stress differed according to level of mother's education, sex of the child, physical and mental health of the mother, child rearing attitudes, mother's level of self-differentiation, marital satisfaction, and father's parenting support. Results of the regression analysis that the etiologic model of this study were that father's parenting support is the most effective variables in rural areas.

• Journal of Korean Academy of Nursing
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• v.28 no.3
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• pp.801-809
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• 1998

This study was carried out the group communication program which I had composed of using the Satir's communication family theory and skills. The purpose of this study was to investigate the effects on the dysfunctional communication self-esteem and depression, executed this program for the mothers group with caring the mental disorders. and then for the test of some hypotheses it was devided two groups ; the experimental group(n=20) and control group(n=25). In the control group they were learned two session family education program in the psychiatric clinics of Pusan National University Hospital and in the experimental group they had experienced during the 10 session by the group communication program. In the methods of the statistics on this datas, it was to statistics X²test for the comparison between the experimental group and control group with general characteristics. The effect of the Group Communication Program was to analyse ANCOVA between pre-post test on the disfunctional communication, self-esteem and depression in the control group and experimental group. The conclusions were derived from the results and test of hypothesis as followings ; 1) The results were tested the differentiation between the experimental and control group, and the pre-post test in the experimental group with dysfunctional communication self-esteem and depression. Some hypothesis were tested and supported as followings : It was supported that the level of dysfunctional communication of the experimental group would be lower than the control group (Hypothesis 1) It was supported that the level of self-esteem of the experimental group would be higher than the control group (Hypothesis 2). It was supported that the level of depression of the experimental group would be lower than the control group (Hypothesis 3). 2) The relation of the dysfunctional communication with the self-esteem was presented negative correlation and with the depression was not correlation. The relation of the self-esteem with the depression was presented significantly negative correlation. The relation of the sacrificuny pattern of dysfuntional communication with the self-esteem was presented negative correlation and with the depression positive correlation.

• International Journal of Quality Innovation
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• v.9 no.3
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• pp.93-112
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• 2008

This study explores the influence of Taiwan's high-tech manufacturers' innovative strategy and innovation motivation concerning the implementation of innovative activities, as well as the influence of innovative activities implementation on business performance. The two intermediate variables, industry group and enterprise scale are also considered. Through a review of the relevant literature, a theoretical model of the influence relationship is developed, while an empirical analysis is simultaneously conducted on Taiwan's high-tech manufacturers. The research result shows that the internal driving force of innovative activities has a significant impact on the level of implementing technological innovative activities and cultural innovative activities. The external driving force of innovative activities has a significant impact on the level of implementing market innovative activities and management innovative activities. Companies adopting self-developed technology and purchased as well as self-developed technology strategies, perform better than those adopting purchased new technology or those with neither purchased nor self-developed technology strategies, at implementing technological innovative activities and cultural innovative activities. The level of implementing innovative activities has a significant influence on business performance (cost reduction and product/service differentiation). For the intermediate variables of "industry group" and "enterprise scale", it is proven in this study that they have no significant influence on the level of innovative activity implementation or business performance.

• Journal of Agricultural Extension & Community Development
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• v.13 no.2
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• pp.235-249
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• 2006

The objective of this study was to investigate the developmental level of Rural Women Leaders Federation(RWLF) which is one of the major rural women`s association in Korea. The writers designed organization measurement tool based on the reviews on the related studies and gather data from 191 memberships of RWLF through the mail questionnaire and interviews. The major findings were as follows; First, the findings shows us this organization as transition period from identification stage to expanded growth stage in developmental stage of rural women's organizations. Second, this organization focus on share of members decision making and leadership style rather than organization`s vision, strategy or organization level. In other words, this organization focus on human relations aspect rather than internal aspect of organization system. Third, this organization has high level of social evaluation of the organization, even if it has low level of personal compensation or individua's social performance. In conclusion, as long-term view-point, it is needed to help them to promote their self-control of survival ability to improve organization's vision, strategy, differentiation for achieving organizational goals. And it also needed to prepare educational programs to increase Rural Women's leadership capability understanding of organizational characteristics and its operation abilities.

• Journal of the Korean Home Economics Association
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• v.40 no.4
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• pp.179-200
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• 2002

The purposes of this study are as follows: (1) how are marital relationships classified by wives' perception of marital conflict and intimacy? (2) how do these types differ in terms of demographic variables (age, income, educational level, and employment status), individual psychological variables (self-esteem, differentiation) and interaction-related variables (affective self-disclosure, conflict resolution styles)?, and what are the relative discriminant powers of these variables in explaining marriage types? The data for this study were collected from 944 married women in Dajeon, who had one or more children, using the structured questionnaire. Classification using median and discriminant analysis were used with SPSS-PC for windows program. The major findings are as follows: The characteristics of each type are as follows: (1) The 'devitalized couples' consist of 18.2% of the whole sample. The levels of positive self-concept and positive interaction are the lowest. (2) The 'intimate couples' consist of 32.6% of the sample. They tend to be found most frequently in the population which is high in the educational level and income level and low in age. While the levels of positive self-concept and positive interaction are the highest, the levels of negative conflict resolution styles are the lowest. (3) The 'intimacy-persuaded couples' take 17.3% of the sample. The levels of positive self-concept and interaction are similar to the 'intimate couples'. (4) The 'conflict-habituated couples' take 31.9% of the sample. Whereas the levels of negative conflict resolution styles are the highest, the levels of positive self-concept and positive interaction are the lowest. The results of this study suggest several implications for the family-life education. It needs to apply different approaches to improve marital quality for each type of marriage.

• Development and Reproduction
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• v.11 no.2
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• pp.59-66
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• 2007

Understanding molecular mechanisms that control embryonic stem cell (ESC) self-renewal and differentiation is important for the development of ESC-based therapies. Statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase), potently reduce cholesterol level. As well as inhibiting cholesterol synthesis, statins inhibit other intermediates in the mevalonate pathway such as farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP), major substrates for protein isoprenylation. Studies showed that pleiotropic effects of statins beyond cholesterol lowering property arise from inhibition of protein isoprenylation that is involved in various cellular functions including proliferation and differentiation. It has been determined that statins have inhibitory effect on ESC self-renewal and stimulatory effect on ESC differentiation into adipogenic/osteogenic lineages. Importantly, statins mediate downregulation of ESC self-renewal by inhibiting RhoA-dependent signaling, independently of their choresterol-lowering properties. Understanding statin's actions on ESCs may provide important insights into the molecular mechanisms that regulate self-renewal or differentiation of ESCs.