• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제4권1호
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• pp.106-113
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• 1993

저자들은 Attention Deficit Hyperactivity Disorder(ADHD) 환자에서 과잉활동증을 동반한 집단과 과잉활동증을 동반하지 않은 집단간에 행동 및 정서적 특성을 비교하고, 각 증상척도들 간의 임상적 관계를 알아보기 위하여 본 연구를 시행하였다. ADHD 환자 36명을 Werry-Weiss-Peters Activity Rating Scale(WWPARS) 평가기준(20점)에 따라 Attention Deficit Disorder with Hyperactivity(ADD+H) 집단 19명과 Attention Deficit Disorder without Hyperactivity(ADD-H) 집단 17명으로 분류하여 Conners Rating Scale(CRS), Home Situations Questionnaire(HSQ), School Situations Questionnair(SSQ), Child Behavior Check-list(CBCL) 등을 시행한 결과 다음과 같은 결과를 얻었다. 1) 두 집단간에 인구학적 특성은 차이가 없었다. 2) ADD+H 집단의 CRS 행동증상척도는 점수는 ADD-H 집단에 비하여 유의하게 높았으며, HSQ와 SSQ를 통하여 가정과 학교에서의 행동문제 상황을 비교한 결과, ADD+H 집단의 행동문제 상황의 유형이나 개수 및 증상의 심도가 ADD-H 집단에 비하여 유의하게 높았다. 3) 각 집단의 CBCL 8개 소척도 점수를 비교하였을 때, ADD+H 집단의 비행척도와 공격성 척도가 유의하게 높았다. 4) ADHD의 행동증상과 CBCL의 행동정서척도 간의 상관관계를 조사한 결과, CRS, WWWPARS의 행동증상척도와 CBCL의 공격성척도, 비행척도, 정서불안정척도 간에는 유의한 양성 상관관계가 있었으며, 특히 공격성척도와 과잉활동증 간에는 매우 유의한 상관성이 있음을 알 수 있었다. 본 연구결과로 미루어 ADHD는 과잉활동증의 유무에 따라 그 임상적 특징이 차이가 있음을 시사하며, 향후 ADHD의 여러 임상적 유형과 약물치료효과 간의 관련성에 대한 연구 및 ADHD 환자에서 행동 특성과 인지기능이 통합된 연구의 필요성이 요구된다.

• 한국자연치유학회지
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• 제9권2호
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• pp.37-45
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• 2020

목적 : 특발성파킨슨병(PD)은 운동증상(떨림, 운동 완서, 경직)과 비운동증상(통찰력과 인지 장애, 기분의 불편함, 우울증, 불안증, 후각 기능장애)이 있다. 이 연구는 호흡, 명상 및 기공 치유로 PD 비운동증상의 개선 효과를 탐색하는 것이 목적이다. 방법 : PD가 있는 대상자(11명)에게 An's-4444힐링호흡, An's관정힐링명상, An's힐링기공치유의 3단계를 1회에 80분 동안 12회 수행하고 치유 전후, 1개월 경과 후 3회 측정하여 측정치를 비교 평가하였다. 결과 : 12회 치유 후 통찰력과 인지장애에 대한 통합 파킨슨병 등급척도(UPDRSI) 수치는 69%, 우울증척도(HAMD)는 61%, 불안증(HAMA)은 64%, 후각 기능장애 냄새식별 테스트(TSI)는 82%로 각각 개선되었다. 치유 1개월 경과 후의 수치는 4개 척도 모두 차이가 없었다. 이는 치유 후 1개월 경과 후까지 효과가 유지됨을 의미한다. 결론 : An's 호흡, 명상 및 기공요법으로 PD비운동증상이 유의성 있게 개선되었다. 특히 후각기능장애 개선으로, 향기를 맡게 되어 삶의 만족도가 향상되었다. 결과는 호흡, 명상 및 기공요법이 PD의 비운동성 증상을 개선 및 치유하는 자연요법으로 가치가 있다고 판단하며, 의생명과학적 추가 연구가 필요하다.

• 생물정신의학
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• 제26권1호
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• pp.14-21
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• 2019

Objectives Thyroid hormone deficiency during the neurodevelopmental period can impair brain development and induce psychiatric symptoms. This study examined the association between thyroid dysfunction and the severity of symptoms in schizophrenia patients, and the treatment response of patients with schizophrenia. Methods Three hundred thirty-eight schizophrenia patients, with no prior history of thyroid disease or taking medication associated with it, were studied. We assessed the blood thyroid hormone level, the Brief Psychiatric Rating Scale (BPRS) scores on the day of admission and discharge, admission period, dose of administered antipsychotics, and the number of antipsychotic combinations. The collected data were subsequently analyzed using the Kruskal-Wallis test and Pearson's chi-square test. Results The percentage of schizophrenia patients who presented with abnormal thyroid hormone level was 24.6%. High total triiodothyronine (TT3) (p = 0.003), low TT3 (p = 0.001), and high free thyroxine (fT4) (p < 0.001) groups showed a higher BPRS score on admission than did the normal thyroid hormone group, while thyroid stimulating hormone (TSH) levels were not significantly correlated with the severity of symptoms. Furthermore, thyroid hormone was not associated with the treatment response assessed by the rate of BPRS score reduction, admission days, use of clozapine, and dose of antipsychotics. Conclusions The TT3 and fT4 hormone levels were significantly associated with the severity of symptoms in schizophrenia patients. These relations suggested that thyroid dysfunction may be associated with the severity of schizophrenia. And hence, further analysis of the results of the thyroid function test, which is commonly used in cases of psychiatric admission, is required.

• 한방재활의학과학회지
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• 제31권4호
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• pp.211-219
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• 2021

This study reports the effectiveness of Korean medicine and Chuna manual therapy on patients with De Quervain's tenosynovitis. Two patients were treated with Chuna manual therapy, electro-acupuncture, moxibustion therapy. We used numeric rating scale (NRS), Finkelstein's test, sonography to measure changes during treatment. After each treatment, NRS, Finkelstein's test, sonography outcome were improved. Korean medicine including Chuna manual therapy can be effectively used to improve De Quervain's tenosynovitis. This study may suggest that korean medicine including Chuna manual therapy can be effective for De Quervain's tenosynovitis.

• Journal of Ginseng Research
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• 제46권1호
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• pp.11-22
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• 2022

Spinal cord injury (SCI) is defined as damage to the spinal cord that temporarily or permanently changes its function. There is no definite treatment established for neurological complete injury patients. This study investigated the effect of ginseng extract and ginsenosides on neurological recovery and antioxidant efficacies in rat models following SCI and explore the appropriate dosage. Searches were done on PubMed, Embase, and Chinese databases, and animal studies matches the inclusion criteria were selected. Pair-wise meta-analysis and subgroup analysis were performed. Ten studies were included, and the overall methodological qualities were low quality. The result showed ginseng extract and ginsenosides significantly improve neurological function, through the Basso, Beattie, and Bresnahan (BBB) locomotor rating scale (pooled MD = 4.40; 95% CI = 3.92 to 4.88; p < 0.00001), significantly decrease malondialdehyde (MDA) (n = 290; pooled MD = -2.19; 95% CI = -3.16 to 1.22; p < 0.0001) and increase superoxide dismutase (SOD) levels (n = 290; pooled MD = 2.14; 95% CI = 1.45 to 2.83; p < 0.00001). Both low (<25 mg/kg) and high dosage (25 mg/kg) showed significant improvement in the motor function recovery in SCI rats. Collectively, this review suggests ginseng extract and ginsenosides has a protective effect on SCI, with good safety and a clear mechanism of action and may be suitable for future clinical trials and applications.

• 한국정밀공학회지
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• 제30권5호
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• pp.559-563
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• 2013

This study aims to quantify the effects of medication (Med) and deep brain stimulation (DBS) on resting rigidity in patients with Parkinson's disease. We tested 10 limbs of five patients under each of four treatment conditions: 1) baseline, 2) DBS, 3) Med, 4) DBS + Med. Rigidity at the wrist joint was assessed using the Unified Parkinson's Disease Rating Scale (UPDRS). The examiner randomly imposed flexion and extension movement on patient's wrist joint. Resistance to passive movement was quantified by viscoelastic properties. Not only rigidity score but also damping constant showed improvements in rigidity by DBS and Med treatments (p<0.05). This indicates that the viscosity can represent the change in rigidity due to DBS as well as Med, which was manifested by UPDRS score.

• 대한중풍순환신경학회지
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• 제8권1호
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• pp.34-39
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• 2007

Objective : To report cases of patients with Parkinson's syndrome. Design : Case-series Patients and methods : 35 of patients with Parkinson's syndrome who visited Department of Cardiovascular and Neurologic Diseases of Kyunghee Oriental Medical Center were treated by acupuncture and herbal medicine from May until December 2007. 35 patients were participated in this study. 21 patients were dropped out during the trial, and we evaluated symptom progress of 14 patients by using several questionnaires such as Unified Parkinson's Disease Rating Scale(UPDRS), modified Hoehn & Yahr stage (H&Y stage) and Schwab & England ADL scale(S&E ADL scale). Results : The whole group consists of 14 male patients and 21 female patients. Mean±SD age range is 64.5±8.4. There were no significant differences of the demographic and clinical characteristics between the case group and drop-out group. The mean±SD medical treatment period of the Case group were 8.4±6.3weeks, the mean±SD of the total score in first medical treatment UPDRS section 1~3 were 29.6±11.0, the mean±SD of the final score were 27.1±12.6, all of which showed significant improvement(p=0.007). There were no significant changes on the H&Y stage and S&E ADL scale. Conclusion : Patients with Parkinson's syndrome who visited Department of Cardiovascular and Neurologic diseases of Kyunghee Oriental Medical Center had a tendency of showing improvement in clinical symptoms.

• The Plant Pathology Journal
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• 제40권1호
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• pp.48-58
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• 2024

The oldest and most extensively cultivated form of millet, known as pearl millet (Pennisetum glaucum (L.) R. Br. Syn. Pennisetum americanum (L.) Leeke), is raised over 312.00 lakh hectares in Asian and African countries. India is regarded as the significant hotspot for pearl millet diversity. In the Indian state of Haryana, where pearl millet is grown, a new and catastrophic bacterial disease known as stem rot of pearl millet spurred by the bacterium Klebsiella aerogenes (formerly Enterobacter) was first observed during fall 2018. The disease appears in form of small to long streaks on leaves, lesions on stem, and slimy rot appearance of stem. The associated bacterium showed close resemblance to Klebsiella aerogenes that was confirmed by a molecular evaluation based on 16S rDNA and gyrA gene nucleotide sequences. The isolates were also identified to be Klebsiella aerogenes based on biochemical assays, where Klebsiella isolates differed in D-trehalose and succinate alkalisation tests. During fall 2021-2023, the disease has spread all the pearl millet-growing districts of the state, extending up to 70% disease incidence in the affected fields. The disease is causing considering grain as well as fodder losses. The proposed scale, consisting of six levels (0-5), is developed where scores 0, 1, 2, 3, 4, and 5 have been categorized as highly resistant, resistant, moderately resistant, moderately susceptible, susceptible, and highly susceptible disease reaction, respectively. The disease cycle, survival of pathogen, and possible losses have also been studied to understand other features of the disease.

• 동의생리병리학회지
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• 제27권1호
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• pp.142-147
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• 2013

The purpose of this study was to report the effect of Korean medicine and acupuncture in jaw tremor with Agitation. We studied two inpatients who had jaw tremor with agitation in the OO University Korean medicine hospital. They was treated with acupuncture (LU8, LR4, HT3, LR2) and herbal medicine. The effect of treatment was evaluated by Visual Analog Scale(VAS) and motor examination of Unified Parkinson's Disease Rating Scale(UPDRSIII). Both VAS of jaw tremor symptom and agitation and UPDRSIII score of tremor were decreased. The result suggest the combination treatment of herbal medicine and acupuncture might be effective for the jaw tremor with agitation.

• 대한중풍순환신경학회지
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• 제13권1호
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• pp.134-141
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• 2012

Object : This clinical study is to report the effects of Chengsimyeonjatang-gamibang on tremors. Methods : Two patients was treated with Chengsimyeonjatang-gamibang and acupuncture that was applied at LU8, LR4, HT3, LR2, GV20, GB20. The effect of treatment was evaluated by Visual Analog Scale(VAS) and Motor examination of Unified Parkinson's Disease Rating Scale(UPDRSIII). Results : After Korean medicine treatment, the patients' VAS and UPDRSIII scores were decreased and conditions were improved. Conclusions : The Korean medicine treatment of Chengsimyeonjatang-gamibang and acupuncture might be effective for the tremors.