• Journal of Nutrition and Health
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• 제35권8호
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• pp.825-833
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• 2002

The effects of dietary supplementation of Eleutherococcus senticosus, taurine and carnitine on maximal endurance exercise performance along with other related parameters were evaluated in rats that underwent aerobic exercise training for 6 weeks. Thirty-two male rats (4 weeks old) were randomly divided into 4 groups, and fed experimental diets and/or aerobic exercise trained according to the protocol: SC (sedentary control group), EC (exercise-trained control group), EE (exercise-trained Eleutherococcus senticosus-supplemented group), and EETC (exercise-trained Eleutherococcus senticosus, taurine and carnitine-supplemented group). The food efficiency ratio of EC rats was significantly lower than the value for SC rats (p < 0.01). Exercise-trained control animals (92 $\pm$ 8.8 min) could run significantly longer until exhausted on the treadmill than sedentary control rats (11 $\pm$ 0.8 min) (p < 0.001). Animals fed an Eleutherococcus senticosus-supplemented diet, and an Eleuthherococcus sonticosus, taurine and carnitine- supplemented diet while undergoing aerobic exercise training for 6 weeks exhibited, respectively, 8 and 5 minutes longer running performance until exhausted than the rats fed the control diet. The gastrocnemius muscle glycogen concentration of the rats, measured at 48 hours post maximal exercise performance test, was 43% higher in EC rats than the value for SC rats (p < 0.05), but was not different among EC, EE, and EETC rats. The mitochondrial citrate synthase activity of the soleus muscle was significantly higher in EC rats compared to the value for SC rats (p < 0.01), and showed a tendency to increase, without statistical significance, in EE or EETC rats compared to the value for EC rats. These results indicate that aerobic exercise training for 6 weeks significantly improved maximal exercise performance, muscle glycogen content along with citrate synthase activity, which are important in the energy metabolism of muscle under aerobic exercise. Dietary supplementation of Eleutherococcus senticosus in rats while undergoing aerobic exercise training improved maximal endurance exercise performance without significantly affecting muscle glycogen content and enzyme activities involved in energy metabolism during exercise. Taurine and carnitine supplementation failed to show an additive effect on maximal endurance exercise performance when consumed along with Eleutherococcus senticosus.

• 대한지역사회영양학회지
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• 제11권1호
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• pp.143-151
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• 2006

Regular exercise training improves body composition, blood lipid profiles and exercise adaptation. This study was conducted to investigate the effect of exercise training at different times of day on body composition, blood lipids, stress hormones and nutrient intakes. Twenty four male graduate students carried out this experiment. The subjects were divided into three groups; morning exercise group, evening exercise group and control group. Two exercise groups performed running and muscular resistance training at mid intensity for 12 week periods. Body composition, blood lipid profiles, blood cortisol, ACTH and nutrient intakes were analyzed prior to, midway and after training. There were significant differences about interaction between different exercise times and training periods in plasma TG and HDL-C of the evening exercise training (p < 0.05). Also the evening exercise group was showed the decreasing of TC after training (p < 0.05). No significant differences about interaction between different exercise times and training periods were shown in body composition, stress hormones and nutrient intakes in the three groups. But evening exercise training decreased body fat ($\%$) and blood ACTH (p < 0.05). Also the increasing of carbohydrate intakes was shown by the evening exercise training (p < 0.05). In contrast, morning exercise group indicated a decrease of body fat ($\%$) after 6 week training (p < 0.05), but this effect was not maintained after 12 weeks of training. These results suggested that regular evening exercise is more effect than morning exercise from the viewpoint of improving body composition, blood lipids, nutrient intakes and exercise adaptation.

• Preventive Nutrition and Food Science
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• 제16권3호
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• pp.278-281
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• 2011

In this study, coffee was shown to effectively inhibit L6 muscle cell death and ATP reduction induced by hydrogen peroxide damage. Additionally, two weeks of oral administration of 7 mg/kg coffee extracts to mice resulted in a 33% increase in treadmill running time relative to that seen in the distilled water administered group. Blood analysis showed decreased lactate content, which was increased by exercise. Thus, these data suggest that coffee intake may enhance exercise capacity and inhibit damage due to excessive exercise.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.375-379
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• 2015

A 45-year-old man presented with dyspnea and hemoptysis during exercise. A chest computed tomography (CT) revealed multifocal diffuse patchy ground glass opacity and interlobular septal thickening in both the lungs. Permeability pulmonary edema or pulmonary hemorrhage was suspected. Serologic studies for autoimmune disorders and vasculitis were negative. There was no laboratory evidence of coagulopathy, other hematopoietic disease or infectious disease. Considering correlation with exercise, we diagnosed exercise-induced pulmonary hemorrhage (EIPH) or exercise-induced pulmonary edema (EIPE). The patient was managed with antifibrinolytics, antibiotics, and antitussive agent. After a week, follow-up chest CT revealed completely resolved pulmonary hemorrhage. About 2 months after the first event, he visited again with dyspnea and hemoptysis during running. In the present study, we report a case of recurrent pulmonary hemorrhage after exercise.

• Preventive Nutrition and Food Science
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• 제3권1호
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• pp.71-76
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• 1998

This study investigated the effect of regular exercise on serum lipid profiles and carnitine levels in college students. Daily nutrient intake, anthropometry , serum lipid, and carnitine profiles in serum and urine were evaluated prior to beginning the study and after 35 days of treadmill running for 30 minutes per day. The results obtained were summarized as follows : 1) Concentrations of total lipid and Triglyceride in serum were decreased by regular exercise in female subjects but unaffected in males. 2) Serum LDL-cholesterol was significantly decreased, but total cholesterol and HDL-cholesterol in serum were not affected in both male and female subjects. 3) nonesterified carnitinem, acid-insoluble acylcarnitine, and total carnitine levels in serum were not affected, but acid-soluble acylcarnitine level was increased by regular exercise in both subjects. 4) Urinary excretionof the acid-soluble acylcarnitine level was increased by regular exercise -training. These results suggest that regular exercise -training has different effects on serum lipid oxidation via carnitine metabolism in this condition.

• 한국운동역학회지
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• 제29권4호
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• pp.247-254
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• 2019

Objective: The goal of this study was to determine the center of pressure (CoP) complexity pattern in approximate entropy technique between genders at different conditions of running speed. Background: It is conducted to evaluate the complexity pattern of CoP in the increment of running speed to have insights to injury prediction, stability, and auxiliary aids for the foot. Method: Twenty men (age=22.3±1.5 yrs.; height=176.4±5.4 cm; body weight=73.9±8.2 kg) and Twenty women (age=20.8±1.2 yrs.; height=162.8±5.2 cm; body weight=55.0±6.3 kg) with heel strike pattern were recruited for the study. While they were running at 2.22, 3.33, 4.44 m/s speed on a treadmill (instrumented dual belt treadmills, USA) with a force plate, CoP data were collected for the 10 strides. The complexity pattern of the CoP was analyzed using the ApEn technique. Results: The ApEn of the medial-lateral and antero-posterior CoP in the increment of running speed showed significantly difference within genders (p<.05), but there were not statistically significant between genders at all conditions of running speed. Conclusion: Based on the results of this study, CoP complexity pattern in the increment of running speed was limited to be characterized between genders as an indicator to judge the potential injury and stability. Application: In future studies, it is needed to investigate the cause of change for complexity of CoP at various running speed related to this study.

• 한국체육학회지인문사회과학편
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• 제51권3호
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• pp.353-362
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• 2012

본 연구는 4주령의 male Wister rat을 대상으로 4주간 등열량 고지방식이 (50% calories from fat) 또는 지구성 운동 (treadmill running, slop 8%, 23m/min, 120분/일, 5일/주)이 미토콘드리아 생합성과 인슐린 저항성에 미치는 영향을 알아보는 것이다. 4주간의 등열량 고지방식이는 일반 사료 집단에 비해 체중과 체지방량에 차이가 없었고, 혈중 포도당, 인슐린 수준 및 골격근내의 인슐린 유발 포도당 이동률도 4주간 등열량 고지방식이 및 일반 사료 집단 간에 차이가 없는 것으로 나타났다. 4주간 등열량 고지방식이와 지구성 운동을 병해 실시한 집단의 체중, 체지방, 혈중 포도당 수준도 다른 3집단과 차이가 없는 것으로 나타났다. 그러나 지구성 운동을 실시한 집단은 고지방식이 집단보다 혈중 인슐린 수준이 유의하게(p<0.05) 낮게 나타났다. 4주간의 등열량 고지방식 또는 지구성 운동은 미토콘드리아 생합성을 증가시키지 않았으나 복합처치의 경우 유의하게(p<0.05) 증가시켰고, 이러한 현상은 혈중 유리지방산의 증가와 함께 나타났다(p<0.05). 이상의 연구 결과들을 종합하면 4주간의 등열량 고지방식과 지구성 운동 복합처치는 인슐린 저항성을 발생시키지 않고 미토콘드리아 표지인자를 유의하게 증가시킴으로 미토콘드리아 생합성을 안정적으로 증가시키는데 좋은 대안이 될 것으로 생각된다.

• 운동영양학회지
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• 제13권2호
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• pp.161-167
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• 2009

The purpose of this study was to investigate whether two different exercises, acute exhaustive exercise and long-term endurance exercise training could affect to the expression of Mn-SOD, HSP70, and PPAR-γ protein in myocardium. The Wistar-Kyoto rats(n=24, 4 weeks) were used and randomly divided into 3 groups; endurance exercise training group (EET, n=8), acute exhaustive exercise group (AEE, n=8) or control group (CON, n=8). EET performed treadmill exercise for 12 weeks (5 days/week, 30~60 min/day). AEE exercised treadmill running (speed increased gradually to 14-26 m/min, 60 min ±10min) until exhausted when EET finished the program. Then, all the rats were sacrificed 48 hours rest at least after the last session of their own exercise program. Hearts were isolated and then the expression of Mn-SOD, HSP70, and PPAR-γ were analyzed by western blotting. One-way repeated ANOVA was used and p value under 0.05 was considered as statistical significance. The results were followed as; the expression of Mn-SOD of AEE was decreased compared with CON. However, the expression of Mn-SOD of EET was increased compared with CON. There was significant difference between AEE and EET in the expression of Mn-SOD. The expressions of HSP70 and PPAR-γ in the both AEE and EET were significantly increased compared with CON. In conclusion, acute exhaustive exercise might induce oxidative stress wheres endurance exercise training could ameliorate the oxidative conditions by increase of Mn-SOD, HSP70, and PPAR-γ. Therefore, we suggested that endurance exercise training could enhance the complementary antioxidant system and improve to prevent apoptosis. Further, a long-term moderat aerobic exercise program might play a important role in mitochondrial biogenesis in the heart.

• 대한지역사회작업치료학회지
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• 제3권2호
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• pp.25-32
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• 2013

목적 : 본 연구는 일반노인에게 시각적 피드백에 따른 발목 움직임 조절 도구를 사용하여 자가 운동을 시행하였을 때 노인의 발목 움직임 조절과 균형능력에 미치는 영향을 알아보고자 하였다. 연구방법 : 이 연구는 사례 연구(case-study)로써, 사전-사후 검사를 실시하였다. 80세인 일반 여성 노인에게 2주 동안 매일 오전, 오후 20분 동안 자가 운동을 실시하였다. 사전, 사후 검사로는 발목 조절 움직임 평가를 위한 Tracking 검사, 균형 능력 측정을 위한 한발로 서기 시간 측정과 Timed up-And-Go검사를 시행하였다. 결과 : 대상자는 Tracking 검사에서 발목 조절 움직임의 향상을 보였다. 균형 능력 평가에서는 한발로 서기유지 시간은 증가하였으나, Timed up-And-Go검사는 변화가 없었다. 결론 : 시각적 피드백에 따른 발목 조절 움직임 도구를 이용한 자가 운동은 노인의 발목 움직임 조절과 균형을 향상 시켰다.

• 운동영양학회지
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• 제25권4호
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• pp.54-58
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• 2021

[Purpose] Deleted in breast cancer 1 (DBC1) ablation causes obesity, and stearoyl-CoA desaturase 1 (SCD1) induces the biosynthesis of monounsaturated fatty acids. This study examined whether voluntary wheel running (VWR) alters SCD-1 and DBC1 protein levels in the liver of leptin-deficient ob/ob mice. [Methods] Twenty-five Ob/Ob mice were divided into two groups (ob/ob-Sed and ob/ob-Ex). The expression of DBC1 and SCD1 in the mouse liver was determined using western blotting. [Results] After 10 weeks, VWR significantly reduced body weight without affecting the fatty acid synthase and CD36 protein levels. The average daily running distance was 4.0±1.0 km/day. This improvement was associated with changes in the hepatic SCD1 and DBC1 levels. Hepatic SCD-1 protein levels increased significantly, and DBC1 protein levels decreased in ob/ob-Sed animals. On the other hand, VWR inhibited the obesity-induced increase in SCD1 expression and impaired the obesity-induced decrease in DBC1 expression in the liver of leptin-deficient ob/ob mice. [Conclusion] This is the first study showing that VWR has strong effects on hepatic SCD1 and DBC1 in ob/ob mice, and provides key insights into the effects of exercise on obesity.