• Title/Summary/Keyword: role structure

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A Possible Physiological Role of Caspase-11 During Germinal Center Reaction

  • Kang, Shin-Jung
    • Animal cells and systems
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    • v.12 no.3
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    • pp.127-136
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    • 2008
  • Caspase-11 has been known as a dual regulator of cytokine maturation and apoptosis. Although the role of caspase-11 under pathological conditions has been well documented, its physiological role has not been studied much. In the present study, we investigated a possible physiological function of caspase-11 during immune response. In the absence of caspase-11, immunized spleen displayed increased cellularity and abnormal germinal center structure with disrupted microarchitecture. The rate of cell proliferation and apoptosis in the immunized spleen was not changed in the caspase-11-deficient mice. Furthermore, the caspase-11-deficient peritoneal macrophages showed normal phagocytotic activity. However, caspase-11-/-splenocytes and macrophages showed defective migrating capacity. The dysregulation of cell migration did not seem to be mediated by caspase-3, interleukin-$1{\alpha}$ or interleukin-$1{\beta}$ which acts downstream of caspase-11. These results suggest that a direct regulation of immune cell migration by caspase-11 is critical for the formation of germinal center microarchitecture during immune response. However, humoral immunity in the caspase-11-deficient mice was normal, suggesting the formation of germinal center structure is not essential for the affinity maturation of the antibodies.

Atelomix in Ethiopian Highland Lakes: their role in phytoplankton dynamics and ecological features

  • Solomon Wagaw;Assefa Wosnie;Yirga Enawgaw
    • Fisheries and Aquatic Sciences
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    • v.26 no.7
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    • pp.423-436
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    • 2023
  • The objectives of this review were to synthesize the community structure of phytoplankton and the role of atelomix in the phytoplankton dynamics in Ethiopian highland lakes. Changes in a lake's physical structure, light dynamics, and availability of nutrients are closely associated with phytoplankton ecology, and phytoplankton assemblages provide insight into phytoplank- ton responses to these environmental changes. Based on the available information, a total of 173 species of phytoplankton are grouped under seven classes, Chlorophyceae (80 taxa), Bacillariophyceae (55 taxa), Cyanophyceae (24 taxa), Dinophyceae (6 taxa), Eugleonophyceae (6 taxa), Xanthophyceae (1 taxon), and Cryptophyceae (1 taxon) were recorded in five different tropical Ethiopian highland lakes. Chlorophyceae and Bacillariophyceae dominated in terms of species composition. Partial atelomixis, seasonality, and low nutrient concentrations seem to be the main drivers in structuring phytoplankton composition and abun-dances in Ethiopian highland lakes, characterized by a high diversity of atelomix-dependent benthic diatoms and desmids. Thus, this review will help understand the role of atelomix and nutrient availability in the phytoplankton composition and biomass of tropical highland lakes of Ethiopia.

A Study on the Antecedent Variables of Relationship Structure Type (기업간 관계구조 관리유형의 선행변수에 관한 연구)

  • 김동진
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.22 no.52
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    • pp.141-153
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    • 1999
  • The focus of marketing study on the strategic tools has shifted from traditional 4Ps'(product, price, place and promotion) to macro relationship marketing which places emphasis on interfirm relationships. The purpose of this study is to develope antecedent variables of relationship type which play the most important role of interfirm relationships, and the antecedent variables of relationship structure comprises three factors : 1) transactional relationship structure, 2) hierarchical relationship structure and 3) embedded relationship structure.

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Analysis on Korea's Economic Volatility: Focusing on the Role of the Service Industry (우리나라 경기변동의 안정성 분석: 서비스산업의 역할을 중심으로)

  • LEE, Jaejoon
    • KDI Journal of Economic Policy
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    • v.33 no.2
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    • pp.1-39
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    • 2011
  • This study discusses the phenomenon behind various forms of macroeconomic volatility faced by countries in terms of industrial structure through empirical analysis, and in the process attempts to validate the role of the service industry. The analysis shows that economic fluctuations in Korea have been significantly improved, mainly due to the country risk. However, Korea is still exposed to the impact of external shocks, which is attributable to the manufacturing-centered industrial structure. Under such industrial structure, it is inevitable for the Korean economy to be continuously exposed to macroeconomic fluctuations caused by global sectoral shocks. So, in order to alleviate business fluctuations, it is necessary to enhance the role of non-tradable sectors that account for most of the service industry.

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Anatomy of the Anterior Cruciate Ligament (A Blueprint for Repair and Reconstruction) (전방십자인대의 해부학)

  • Jung, Young-Bok;Yum, Jae-Kwang
    • Journal of the Korean Arthroscopy Society
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    • v.1 no.1
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    • pp.1-8
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    • 1997
  • The anterior cruciate ligament(ACL) is, perhaps, the most intriguing component of the knee joint. Initially referred to crucial ligament because of the cruciate or crossed arrangement or the anterior and posterior ligaments within the knee. the irony or the ACL being crucial to the well-being or the joint has only recently appreciated. The anterior cruciate ligament of human knee joint is a complex structure and its orientation, construct and biology arc directly related to the knee function as a constraint of knee joint motion. In addition to its functional role as a static stabilizer or the knee. the ACL has a unique neurovascular system. The vascular anatomy of the ACL plays a crucial role in the repair and reconstruction of the ligament, and the neuroreceptors found in its substance suggest a possible proprioceptive role for the ligament. The structural complexity of the ACL allows the ligament to function through the normal range of motion as a static stabilizer or the knee. hut it also makes the exact duplication of this structure very difficult. A comprehensive knowledge or the anatomy of the ACL can provide the orthopedic surgeon with a blueprint for the idealized repair and reconstruction of this most complex structure.

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An Efficient Role Based Access Control Technique by Structuring of Role Specification Certificate (역할 명세 인증서의 구조화에 의한 효율적 역할기반 접근제어 기법)

  • Yang, Soo-Mi
    • Journal of Internet Computing and Services
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    • v.6 no.5
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    • pp.1-9
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    • 2005
  • In a role based access control through attribute certificate, the use of role assignment certificates and role specification certificates can reduce management cost and the overhead incurred by changing roles, Highly distributed computing environments such as ubiquitous computing environments not having global or broad control. need another attribute certificate management technique, Actually just having role specification certificate separately reduce management cost, But for better performance we structure role specification, We group roles and make the role group relation tree, It results secure and efficient role renewing and distribution, For scalable role specification certificate distribution, the multicasting of packets is used, We take into account the packet lass and quantify performance enhancements of structuring role specification certificates.

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The Analysis of Costume Role in Shakespearean Tragedy (셰익스피어의 비극작품에 나타난 복식역할의 분석)

  • Jeong, Hyun Sook;Kim, Jin Goo
    • Journal of the Korean Society of Clothing and Textiles
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    • v.17 no.3
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    • pp.436-447
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    • 1993
  • This study concerns the role of costume in Shakespearean tragedy from the viewpoint of the role theory. The term "role" has been used to represent the behavior expected of the occupant of a given position or status. A specific role can not be successfully performed without the aid of the Costumes. Costumes are adopted in relation with a specific role. The role of social status and position reflects sex, age, occupation, class, economic position of the characters. In his works, the crown and the mace represented not only the throne but also a previllege and supreme position. The sitution role of costume could be widely used for visualizing the psychological situation and external environments of the characters on the stage. The disguise role hided one's status, thereby makes possible acting others position. And the disguise role can bring about the change of status, age, sex, occupation, and atmosphere. The costume could be used as a voucher of love. The costume performed the role of the physical and psychic protection, and provided its wearer with consolation and peaceful mind. The costume reflected the custom of a society through its wearing condition and wearing configuration. The results obtained from this study can provide useful cues for understanding the role action in the social structure. This kind of understanding reveals the costume phenomena in real life, allows one to perform roles properly and efficiently, and opens our insight on the overall aspects of the costume culture.

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A Study on the Relationships Between the chief Nurse′s Leadership style and the organizational climate of Hospitals (간호과장의 지도성 유형과 병원 조직풍토와의 관계)

  • 김영매;한상임
    • Journal of Korean Academy of Nursing
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    • v.5 no.1
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    • pp.79-86
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    • 1975
  • It had been thought the role of Nursing administrator was still not started along the right line in Korea because of the Lacking of full understanding and recognition of the real meaning of administrator's role, and because there are several Rinds of problems and difficulties in actual role. The present study is an attempt to clarify some existing relationships between the chief Nurse's Leadership style and the organizational climate of Hospitals. The problems of the study are specifically started as follows ; 1) What influence does the individual behavior have on the formation of the organizational climate of Hospital? 2) From what do the difference of climate arise? 3) How are the individual be heavier and organizational climate of Hospital measured ? In order to see the relationships or the interactions between the two factors, the chief nurse's Leadership style and organizational climate of hospital , the researcher has classified. He former into; 1) effective Leadership style. 2) initiating structure leader ship style. 3) Consideration structure Leadership style, and 4) ineffective Leadership style, and the latter in to. 1) open climate and 2) closed climate The Chief Nurses Leadership style has been. Classified into consideration-human relations approaches and initiating structure approaches according to L. B. D. Q by Hapin. Organizational climate of hospital has been classified into open-closed continuum according to O. C. H Q. by Hairpin and Croft. The results obtained are as follows : 1) The chief nurse's Leadership style is closer to Initiating structure Leadership style than Consideration structure lure Leadership style. 2) The organizational climate of hospital is closer to open climate than closed climate. 3) The chief nurse's Leadership sty]e and the organizational climate of hospital to not show any significant relations.

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Role of Energy and Composition of Film-Forming Species in Formation of Composition and Structure of Compound Films

  • Shaginyan, L.R.
    • Journal of the Korean institute of surface engineering
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    • v.34 no.5
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    • pp.455-464
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    • 2001
  • Effect of bombardment of the growing film by energetic particles on its properties is know over many years and is widely used for modification of the film properties. Despite of this there are no final answers on such questions as: what is the mechanism of compositional changes that take place for some compound films deposited under the ion bombardment, how the ion bombardment influences the epitaxial growth, what mechanisms govern the growth of the film on its early stages during deposition under the ion bombardment. The role of composition of film-forming species in formation of film structure is barely investigated or even not investigated at all. Experimental evidence and discussion of the influence of ion bombardment and composition of film-forming species on structure and composition of compound films are briefly considered in the review.

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NONTHERMAL COMPONENTS IN THE LARGE SCALE STRUCTURE

  • MINIATI FRANCESCO
    • Journal of The Korean Astronomical Society
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    • v.37 no.5
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    • pp.465-470
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    • 2004
  • I address the issue of nonthermal processes in the large scale structure of the universe. After reviewing the properties of cosmic shocks and their role as particle accelerators, I discuss the main observational results, from radio to $\gamma$-ray and describe the processes that are thought be responsible for the observed nonthermal emissions. Finally, I emphasize the important role of $\gamma$-ray astronomy for the progress in the field. Non detections at these photon energies have already allowed us important conclusions. Future observations will tell us more about the physics of the intracluster medium, shocks dissipation and CR acceleration.