• Proceedings of the Zoological Society Korea Conference
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• 1996.10a
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• pp.82.2-82
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• 1996

No Abstract, See Full Text

• Proceedings of the Korean Society of Environment and Ecology Conference
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• 2005.04a
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• pp.157-160
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• 2005

• Proceedings of the Korean Society of Environment and Ecology Conference
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• 2005.04a
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• pp.161-163
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• 2005

• Proceedings of the Korean Society of Environment and Ecology Conference
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• 2006.04a
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• pp.136-139
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• 2006

• Proceedings of the Korean Society of Environment and Ecology Conference
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• 2007.04a
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• pp.105-108
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• 2007

• Proceedings of the Korean Society of Environment and Ecology Conference
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• 2007.04a
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• pp.109-111
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• 2007

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.29-30
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• 2003

The whole genome sequences, mapped for humans and rodents, and technical capability of monitoring whole genome expression in a high throughput fashion enable us to perform the "whole genome profiling". The major characteristics of this profiling from the toxicological point of view are that the overt phenotypes are not the essential factors for the construction of toxicity database/informatics.(omitted)

• The Journal of the Korean Society for Microbiology
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• v.21 no.3
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• pp.331-336
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• 1986

A microbiological study for the isolation and characterization of Leptospira interrogans was performed in an attempt to define the characteristics of Leptospirosis in Korea. The results are summerised as follows. Thirty-five cultures were isolated from 11 patients with leptospirosis and 24 wild rodents captured in Paju area. The isolation rate of Leptospira from wild rodents reached 23.1%. All 35 cultures were identified as Leptospira interrogans by their characteristic morphology and motility in dark field microscopy, pathogenecity in Guinea pig and sensitivity to 8-Azaguanine. Cultures formed diffuse subsurface colonies with hazy margin and were catalase, peroxidase and oxdase positive. The fifty percent lethal dose of isolate HM 4 in Guinea pig was $8.9{\times}10^4$ org. Mouse passage method was sucecssfully applied in maintenance of fresh isolates without any loss of their original virulency.

• Journal of Korean Society of Forest Science
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• v.94 no.2 s.159
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• pp.108-111
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• 2005

This study was conducted to identify the road effect on small rodent populations within fragmented forest areas around the road from June to September 2002, in 9 study sites of Baekdugdaegan mountains, Korea. Two species of small rodents, Korean field mouse Apodemus peninsulae and striped field mouse Apodemus agrarius, were captured in this study. Korean field mouse preferred forest area, and striped field mouse generally has been found edge area around road. Mean body weight of Korean field mouse was significantly different, but that of striped field mouse was not between both distance from road. Korean field mouse is forest-dwelling species and their distribution is limited in forest area. In contrast, striped field mouse has wide distributional range around road. The effects of road is different in each small rodent species and their habitat preferences.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.15-23
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• 2003

Interest in the regulation of body weight and the pathological physiology of obesity has been rekindled by the cloning of the obese(ob) gene and identification of its product, leptin, in 1994. The first publication appeared in Nature and is a milestone of obesity research. The remarkable metabolic effects of leptin in rodents are: a) inhibition of food intake, b) stimulation of energy expenditure, and c) reversal of obesity. These effects, though mostly desirable, have not been fully demonstrated in humans. The central action of leptin in the regulation of body weight includes two pathways in rodents: a) When the body weight increasing, more leptin is secreted from adipose tissue, which acts on hypothalamus, probably through a POMC or MSH pathway via M4 receptor, initiates a series of response to obesity, i.e. sympathetic tone increased, energy expenditure enhanced and food intake reduced. b) When body weight reduced, leptin concentration decreased with the shrinkage of fat mass, which may also act on the hypothalamus, probably through a NPY-Y5 receptor pathway. Then a cascade of response to hungry was induced, i.e. increase of parasympathetic tone and food intake, decrease of energy expenditure and body temperature, as well as shut-down of the reproductive function.