• Journal of Periodontal and Implant Science
• /
• v.43 no.2
• /
• pp.96-100
• /
• 2013

Purpose: Chronic periodontitis (CP) seems to be associated with stress and depression, but little information on this possible association is available in the literature. Thus, the objective of this study was to evaluate the association among stress, the salivary cortisol level (SCL), and CP. Methods: Seventy systemically healthy subjects were included in the study from January to September 2011. Full medical and dental histories were obtained, and the following measurements were recorded: 1) probing depth; 2) clinical attachment level; 3) bleeding on probing; and 4) tooth mobility. Saliva samples were collected for the evaluation of SCL (via a highly sensitive electrochemiluminescence immunoassay), and all subjects also answered a questionnaire (i.e., the Zung Self-rating Depression Scale). The odds ratio (OR) with a 95% confidence interval (CI) was calculated, and one way analysis of variance and the Tukey-Kramer method were performed. Results: A total of 36 subjects with CP (51.4%) and 34 without CP were evaluated. Of them, all of the subjects with CP and one periodontally healthy subject were diagnosed with depression. Subjects with moderate CP had statistically significantly higher levels of SCL than subjects with a diagnosis of slight CP (P=0.006). Also, subjects with severe CP showed the same outcome when compared to those with slight CP (P=0.012). In addition, 46 subjects presented high SCL whereas 24 had a normal level. CP was found to be correlated with the SCL, with an OR of 4.14 (95% CI, 1.43 to 12.01). Conclusions: Subjects with a high SCL and depression may show an increased risk for CP.

• YAKHAK HOEJI
• /
• v.55 no.2
• /
• pp.81-90
• /
• 2011

Most antineoplastic agents are nonselective in their mechanism of action, affecting noncancerous as well as cancerous cells, and resulting in acute effects such as irritation of mucous membranes and chronic effects such as genotoxicity, teratogenicity, and carcinogenicity. Healthcare workers occupationally exposed to antineoplastic agents are at risk. The present study aimed to develop and apply methods to monitor occupational exposure to antineoplastic agents, using cyclophosphamide (CP) as the model compound. To monitor environmental and biological exposure, potentially contaminated surfaces were wiped and 24 hour urine samples were collected from workers. Liquid chromatography combined with tandem mass spectrometry was performed, with a limit of detection of 0.05 ng/ml. Measurable amounts of CP were detected on 92% of the sampled surfaces, with a geometric mean of 175.22 $ng/m^2$. Despite the environmental contamination of the model compound, CP was below the detection limit in all urine samples. If workplace contamination cannot be completely avoided, it is importance to reduce exposure to the lowest possible levels. To this aim, efforts to minimize occupational exposure along with biological and environmental monitoring are required. The standardized sampling techniques, and specific and sensitive analytical methods reported in this study may be helpful in assessing occupational exposure and devising strategies to reduce exposure.

• Journal of the Korean Operations Research and Management Science Society
• /
• v.29 no.2
• /
• pp.97-116
• /
• 2004

Recently, e portion of on-line stock brokerage has been rapidly increased to be more than 50%, on the basis of contracted money. The usage of wCTS(Web Based Cyber Trading Systems) has now got into the steady state over the initial diffusion stage, which means wCTS has got more-than-half customer base in on-line service. Therefore, brokerage service providers have their competitive strategic focus on customer retention through the enhancement of customer loyalty. This study provides framework and survey results on explanation of wCTS user's loyalty, what and how factors affect wCTS user's loyalty. We adopt the results of early studies on information technology acceptance and diffusion such as TAM(Technology Acceptance Model) and IDT(Innovation Diffusion Theory). We also referred loyalty theory of marketing area and studios on CTS usage. We categorized explanation factors as three groups characteristics of users, characteristics of system, social environment. And we assumed that these three factors could affect the loyalty through two parameters : customer satisfaction and trust to the system. This study firstly shows that the ease of use and usefulness, the major factors of TAM. can also be applied to the loyalty of wCTS with resulting that the usefulness is more important than the ease of use In wCTS. Secondly, it shows that the innovative and risk-sensitive user has the lower degree of loyalty. Thirdly, it shows that the satisfaction and trust impact the loyalty simultaneously, the trust particularly impacts more strongly than the loyalty, due to the characteristics of monetary transaction in wCTS. This study provides meaningful results to the other on-line EC service fields as a first empirical research regarding the loyalty to wCTS which is a typical on-line EC service.

• Korean Management Science Review
• /
• v.30 no.1
• /
• pp.73-89
• /
• 2013

This paper develops an investment algorithm based on Markowitz's Portfolio Selection Theory, using historical stock return data, and empirically evaluates the performance of the proposed algorithm in the U.S. and the Hong Kong stock markets. The proposed investment algorithm is empirically tested with the 30 constituents of Dow Jones Industrial Average in the U.S. stock market, and the 30 constituents of Hang Seng Index in the Hong Kong stock market. During the 6-year investment period, starting on the first trading day of 2006 and ending on the last trading day of 2011, growth rates of 12.63% and 23.25% were observed for Dow Jones Industrial Average and Hang Seng Index, respectively, while the proposed investment algorithm achieved substantially higher cumulative returns of 35.7% in the U.S. stock market, and 150.62% in the Hong Kong stock market. When compared in terms of Sharpe ratio, Dow Jones Industrial Average and Hang Seng Index achieved 0.075 and 0.155 each, while the proposed investment algorithm showed superior performance, achieving 0.363 and 1.074 in the U.S. and Hong Kong stock markets, respectively. Further, performance in the U.S. stock market is shown to be less sensitive to an investor's risk preference, while aggressive performance goals are shown to achieve relatively higher performance in the Hong Kong stock market. In conclusion, this paper empirically demonstrates that an investment based on a mathematical model using objective historical stock return data for constructing optimal portfolios achieves outstanding performance, in terms of both cumulative returns and Sharpe ratios.

• Journal of Microbiology and Biotechnology
• /
• v.26 no.11
• /
• pp.1855-1862
• /
• 2016

Cronobacter sakazakii (C. sakazakii) is a foodborne pathogen, posing a high risk of disease to infants and immunocompromised individuals. In order to develop a quick, easy, and sensitive assay for detecting C. sakazakii, a rabbit anti-C. sakazakii immunoglobulin G (IgG) was developed using sonicated cell protein from C. sakazakii. The developed anti-C. sakazakii (IgG) was of good quality and purity, as well as species-specific. The developed rabbit anti-C. sakazakii IgG was attached to the surface of a sulforhodamine B-encapsulated liposome to form an immunoliposome. A test strip was then prepared by coating goat anti-rabbit IgG onto the control line and rabbit anti-C. sakazakii IgG onto the test line, respectively, of a plastic-backed nitrocellulose membrane. A purple color signal both on the test line and the control line indicated the presence of C. sakazakii in the sample, whereas purple color only on the control line indicated the absence of C. sakazakii in the sample. This immunochromatographic strip assay could produce results in 15 min with a limit of detection of $10^7CFU/ml$ in C. sakazakii culture. The immunochromatographic strip assay also showed very good specificity without cross-reactivity with other tested Cronobacter species. Based on these results, the developed immunochromatographic strip assay is efficient for the detection of C. sakazakii and has high potential for on-site detection.

• Journal of IKEEE
• /
• v.24 no.1
• /
• pp.132-139
• /
• 2020

The ionizer module used in this air cleaner supplies high voltages of 3.5KV / -4KV to the discharge electrode HV+ / HV- using a winding transformer to generate positive and negative ions by electric field radiation of carbon fiber brush. The ionizer module circuit using the existing MCU has the disadvantage of large PCB size and expensive price, and the gate driver chip using the existing ring oscillator has oscillation period sensitive to PVT (Process-Voltage-Temperature) fluctuation and there is risk of fire or electric shock because there is no fault detection function by short circuit of HV+ and GND as well as HV- and GND. Therefore, in this paper, even though PVT fluctuates, by using 7-bit binary up counter, HV+ voltage reaches the target voltage by adjusting oscillation period. And an HV+ short fault detection circuit for detecting a short circuit between HV+ and GND, an HV- short fault detection circuit for detecting a short circuit between HV- and GND, and an OVP (Over-Voltage Protection) for detecting that HV+ rises above an overvoltage are newly proposed.

• Korean Journal of Environmental Biology
• /
• v.32 no.1
• /
• pp.68-74
• /
• 2014

Scientific study has investigated the body condition differences by habitat characteristics in larvae Korea salamander (Hynobius leechii) from March to April in 2012. To examine the sensitivity of external environment (predation risk), we divided two groups according to habitat characteristic; 1) Permanent pond and 2) Temporary pond. Howere, each larva was measured by head width at the level of the eye (HWE), largest head width (LHW) and snout-vent length, and we calculated the ratio of the head size by dividing HWE/LHW. As a result, larvae were larger in permanent pond group, had a faster growth rate than in temporary pond group. When exposed to the predator, larvae in permanent pond were smaller HWE/LHW than larvae in permanent pond. Therefore, these results indicate larvae in temporary pond more sensitive to the external environment.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.24 no.2
• /
• pp.373-384
• /
• 2014

The social network service is the bidirectional media that many users can build relations not only friends but also other people. However, a process to approach in the social network is so simple that untrustable information, which malignant users make, is spreaded rapidly in many the social network uses. This causes many users to suffer material or psychological damages. Because of openness in the social network, there will be higher risk of the privacy invasion. Therefore, sensitive information should be transferred or provided only to reliable users. In general, because many users exchange among one hops, many researches have focused on one hop's trust evaluation. However, exchanges between users happen not only one joint bridege but also far nodes more than two nodes on account of dense network and openness. In this paper we propose the efficient scheme combining transitivity and composability for remote users.

• The Korean Journal of Food And Nutrition
• /
• v.30 no.4
• /
• pp.780-787
• /
• 2017

The consumption of high-salt foods is an independent risk factor for increased hypertension. Thus, evaluating the relationship of taste sensitivity and pleasantness of high-salt foods such as Korean jang products, would help contribute to an understanding of salty food eating behaviors of the Korean rural elderly. This study aimed to verify the association between taste sensitivity and salinity of Korean jang products, and the preferences of food groups and nutrient intake in the rural elderly. We studied 269 elderly persons (males 83, females 186) aged above 65 years, residing in the rural area, Sunchang gun Jeonbuk. For each subject, a recognition threshold of 4 basic tastes and pleasant concentrations of NaCl were estimated using the sip- and-spit method. Taste preferences, frequency of intake of food groups, nutrient intakes, and salinity and sweetness of Korean jang products (Doenjang, Ganjang, Gochujang) were assessed. No association was found between salt taste recognition threshold and optimally preferred concentration of salt and salinity of Korean jang products. However, the sweet taste recognition threshold was positively related to the sweetness of Korean jang products. Also, the salinity of Doenjang positively correlated with the frequencies of food groups and nutrient intakes. That is to say that the sweet taste sensitivity was related to the sweetness of Korean jang products, but was not sensitive to the salty taste. The salinity of Doenjang correlated with the consumption of food and nutrient intakes. Taken together, these findings suggest the need for appropriate intervention and education to reduce the salinity of Doenjang, which is an important modifiable factor contributing to reducing sodium intake in the rural elderly.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2016.05a
• /
• pp.267-267
• /
• 2016

Extreme events, such as Winnie(1987), Rusa(2002), Maemi(2003) at sea-side urban area, resulted not only economic losses but also life losses. The Korean sea-side characterisitcs are so complicated thar the prediction of sea level rise makes difficult. Geomophologically, Korean pennisula sits on the rim of the Pacific mantle so the sea level is sensitive to the surges due to earth quake, typoon and abnormal climate changes. These environmetns require closer investigation for the preparing the inundatioin due to the sea level rise with customized prediction for local basin. The goal of this research is provide the information of inundation risk so the sea side urban basin could be more safe from the natural water disastesr.