• 한국균학회소식:학술대회논문집
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• 2016.05a
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• pp.39-39
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• 2016

There is a growing consumer preference for self-medication, which has resulted in the growth of the Korean functional food market to \1.5 trillion in 2014. Functional foods that can modulate immune responses and enhance liver health are in the top 2 product-specific health functional food categories. The aim of this project was to develop and commercialize new health functional foods incorporated with Cordyceps militaris. Cordyceps genus includes about 400 species, many of which have been used as traditional medicines for many years in Asian countries. C. militaris belongs to the class Ascomycetes and has been used extensively as a crude drug and tonic food in East Asia. Owing to the various physiological activities of its main active constituent, cordyceptin, C. militaris is currently being used for multiple medicinal purposes. Recently, many studies have tried to elucidate the pharmacological mechanisms underlying the activities of Cordyceps spp., which include immune activation, anti-inflammatory, anticancer, and antiviral effects. After continuous attempts and research toward industrialization, C. militaris cultivated using brown rice was developed into a product by a standardized process and mass-cultivating system. It was successfully introduced into the market and was approved as a functional food ingredient for the first time in Korea. Based on this information, C. militaris containing functional food product for strengthening the immune system was released in August 2014 under the brand name "Dongchoong Ilgi." Dongchoong Ilgi is potentially beneficial for improving immune and liver functions and may enhance both the convenience and effectiveness of health functional foods taken by healthy people and patients with minor illness. In addition, the results of our study may be applicable for the development of health functional foods that could lower the risk of diseases such as the common cold and cancer.

• Convergence Security Journal
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• v.9 no.4
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• pp.1-6
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• 2009

Current paradigm of industrial security is changing into the effective operation and management from simple establishment of security equipments. If the physical security system(entry control system, video security system, etc.) and the IT integrated security control system are conversed, it makes us possible to prevent, disrupt and track afterwards the insider's information leakage through the risk and security management of enterprise. That is, Without the additional expansion of the existing physical security and IT security manpower, the establishment of systematic conversion security management process in a short time is possible and can be expected the effective operation of professional organization system at all times. Now it is needed to build up integrated security management system as an individual technique including the security event collection and integrated management, the post connected tracking management in the case of security accident, the pattern definition and real time observation of information leakage and security violation, the rapid judgement and response/measure to the attempt of information leakage and security violation, the establishment of security policy by stages and systematically and conversion security.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2007.11a
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• pp.643-646
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• 2007

As increase of the land price at downtown area, it makes people more and more interested of improving the space utilization such as makes buildings bigger, deeper and higher. Therefore, the importance of the underground construction which is the basic principle has been increased. As constructors have to complete underground construction as soon as possible with the minimum costs, they concentrate on the whole process of underground structure. Although they makes every these efforts, construction failure still happen because of the uncertainty of the condition of soil and the unexpected danger of underground construction. To make matter worse, there are only some examples without detailed information like 'how much this breakdown damage to the construction?' so it is the anther problem that most of people doesn't recognize the economical negative impact of underground structure breakdown. This report would make people understood the importance and risk of the underground construction by showing some analysis which was assumed from the real accidents.

• The Journal of the Korean dental association
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• v.49 no.10
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• pp.618-627
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• 2011

Cigarette smoking is a significant risk factor for periodontaldiseases and implant treatments. Smoking control is regarded as a key to the success of dental treatments as well as the well-being of the patients. The aim of this study was to reviewthe effects of smoking on periodontal health, and the results of periodontal therapy and implant treatments. Also, in vitro, microbiological, immunological and epidemiological relationships were studied. In vitro studies show that smoking interferes with normal healing process and increased tissue destruction. There is still controversy on the population of microbes of smokers. Smokers showed significantly less gingival inflammation and bleeding on probing compared with non-smokers. After periodontal treatments, a compromised clinical outcome was noted for smokers in terms of pocket depth reduction and gain in attachment levels. In conclusion, data from in vitro, epidemiological, cross-sectional and case-control studies strongly suggest that quitting smoking is beneficial to patients before periodontal and implant treatments.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.4
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• pp.967-972
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• 2007

Osteoporosis is the most prevalent metabolic bone disease and is characterized by diminished bone strength predisposing to an increased risk of fracture. We investigated the effects of the extract from Acyranthes Radix on the progress of bone loss in ovariectomized rats for 6 weeks. Female Sprague-Dawley 40 rats of 3-4 weeks, weight 200 ${\pm}$ 10g were divided into two groups including the sham operation group(8 rats) and ovariectomy group(32 rats). The dose-dependent effect of Acyranthes Radix extract on bone mineral density and biochemical testing was assessed in ovariectomized rat. Body weights were increased in all groups was higher in experimental group than sham operation group. The level of bone mineral density, GPT, and serum P concentration, ALP were increased experimental group, but a little increase in sham operation group at same period. This longitudinal study result made conclusion that Acyranthes Radix extract treatment appeared to improve the osteoporosis delaying the progression to the osteoporotic process in rats.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.22 no.8
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• pp.89-95
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• 2008

This paper describes the checking results and some problems of guard lamps installed in the field. The guard lamp providing night security for people is installed outdoors and exposed to the natural factors causing secular ageing and the people's vandalism, etc., thus it is prone to get troubles in function. In fact, the guard lamps has been left without considering the fundamental measures in the legislative system in spite of the loss of lives due to the electric shock accidents repetitively taking place every year. This study arouses people's attention to the risk due to the lack of management and maintenance of the guard lamp by investigating the recent technology and the actual operating conditions and some problems and countermeasures were ultimately deduced. In this process, we reflected on the various opinions through fieldwork and had a couple of consultations with field staffs, manufacturers concerned and active officers with local autonomous entities.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.1
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• pp.47-52
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• 2006

Recent warnings indicate that there is a potential risk of massive earthquake in Japan within 30 years. These earthquakes could produce large-scale tsunamis. Tsunamis are very powerful and can be traveled thousands of miles and caused damage in many countries. Consideration of the effect of tsunami to the moored ship is very important because it brings the loss of life and vast property damage. In this paper, the numerical simulation procedure to analyze the motions of a moored ship due to the observed waves of tsunami, Tokachi-off earthquake tsunami profile in northern Pacific coasts of Japan on September 26 in 2003. And the effects on the motions and mooring loads are investigated by numerical simulation. Numerical simulations consist of hydrodynamic analyses in a frequency domain and ship motion analyses in a time domain as the motions of moored ships are examined. As the process begins, the hydrodynamic and waveexciting forces for moored ships must be calculated. Ship motions and mooring forces can then be calculated by solving the equations of motion. In order to investigate the safety evaluation on the motions of moored ship by tsunami attack, we applied a numerical simulation procedure to a 135,000m3 LNG carrier moored at an offshore sea berth.

• Genomics & Informatics
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• v.11 no.4
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• pp.211-217
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• 2013

Many biobanks were established as biorepositories for biomedical research, and a number of biobanks were founded in the 1990s. The main aim of the biobank is to store and to maintain biomaterials for studying chronic disease, identifying risk factors of specific diseases, and applying personalized drug therapies. This report provides a review of biobanks, including Korean biobanks and an analysis of sample volumes, regulations, policies, and ethical issues of the biobank. Until now, the top 6 countries according to the number of large-scale biobanks are the United Kingdom, United States, Sweden, France, the Netherlands, and Italy, and there is one major National Biobank of Korea (NBK) and 17 regional biobanks in Korea. Many countries have regulations and guidelines for the biobanks, and the importance of good management of biobanks is increasing. Meanwhile, according to a first survey of 456 biobank managers in the United States, biobankers are concerned with the underuse of the samples in their repositories, which need to be advertised for researchers. Korea Biobank Network (KBN) project phase II (2013-2015) was also planned for the promotion to use biospecimens in the KBN. The KBN is continuously introducing for researchers to use biospecimens in the biobank. An accreditation process can also be introduced for biobanks to harmonize collections and encourage use of biospecimens in the biobanks. KBN is preparing an on-line application system for the distribution of biospecimens and a biobank accreditation program and is trying to harmonize the biobanks.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2005.11a
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• pp.241-250
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• 2005

New product development (NPD) is defined as the transformation of a market opportunity and a set of assumptions about product technology into a product available for sale. Managers charged with project selection decisions in the NPD process, such as go/no-go choices and specific resource allocation decisions, are faced with a complicated problem. Therefore, the ability to develop new successful products has identifies as a major determinant in sustaining a firm's competitive advantage. The purpose of this study is to develop a new evaluation model for NPD project selection in the high -tech industry using support vector machines (SYM). The evaluation model is developed through two phases. In the first phase, binary (go/no-go) classification prediction model, i.e. SVM for high-tech NPD project selection is developed. In the second phase. using the predicted output value of SVM, feasibility grade is calculated for the final NPD project decision making. In this study, the feasibility grades are also divided as three level grades. We assume that the frequency of NPD project cases is symmetrically determined according to the feasibility grades and misclassification errors are partially minimized by the multiple grades. However, the horizon of grade level can be changed by firms' NPD strategy. Our proposed feasibility grade method is more reasonable in NPD decision problems by considering particularly risk factor of NPD in viewpoints of future NPD success probability. In our empirical study using Korean NPD cases, the SVM significantly outperformed ANN and logistic regression as benchmark models in hit ratio. And the feasibility grades generated from the predicted output value of SVM showed that they can offer a useful guideline for NPD project selection.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.24 no.2
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• pp.373-384
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• 2014

The social network service is the bidirectional media that many users can build relations not only friends but also other people. However, a process to approach in the social network is so simple that untrustable information, which malignant users make, is spreaded rapidly in many the social network uses. This causes many users to suffer material or psychological damages. Because of openness in the social network, there will be higher risk of the privacy invasion. Therefore, sensitive information should be transferred or provided only to reliable users. In general, because many users exchange among one hops, many researches have focused on one hop's trust evaluation. However, exchanges between users happen not only one joint bridege but also far nodes more than two nodes on account of dense network and openness. In this paper we propose the efficient scheme combining transitivity and composability for remote users.