• 제목/요약/키워드: risk factor to diabetes

검색결과 299건 처리시간 0.024초

중풍 발병 부위별 위험요인 및 전조증상 조사연구 (Investigation on Risk Factor and Warning Signs According to Stroke Lesion)

  • 정재한;선종주;민인규;김미영;최원우;홍진우;나병조;정우상;문상관;조기호;김영석
    • 대한한방내과학회지
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    • 제28권4호
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    • pp.808-815
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    • 2007
  • Objectives : This study investigated stroke lesions and their relationship with warning signs and risk factors in stroke patients. Methods : Three hundred fifty-three stroke patients were recruited at the Department of Cardiovascular and Neurologic Diseases (stroke center) of Kyung Hee University Oriental hospital from October 2005 to July 2007. We evaluated their stroke lesions with brain MRI, their warning signs, and risk factors. Results : 353 subjects were included in the final analysis. The frequency of diabetes was found more in presence of brain stem lesion than without. The cortex lesion showed a close relationship with smoking, drinking and the frequency of one side paralysis or weakness. These were more common in males than in females. Conclusions : We observed stroke lesions and their characteristics in stroke patients. The subjects' brain lesions seemed affectedby the risk factors. A concrete conclusion can hardly be drawn from this study; additional research is necessary.

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도뇨관 관리를 위해 가정간호에 의뢰된 환자의 요로감염실태 (Urinary Tract Infections in Catheterized Patients Receiving Home Care Nursing)

  • 박민아;이종은;조영이;장정숙;최지연
    • 가정∙방문간호학회지
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    • 제28권2호
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    • pp.178-185
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    • 2021
  • Purpose: In this study, we aimed to explore the risk factors for catheter-associated urinary tract infections (CAUTI) in patients receiving home care nursing. Methods: A total of 117 participants registered for home care nursing provided by the University of C hospital in Seoul were included in the study. Data were based on a survey and urine examination results from June to July 2018. Results: Asymptomatic bacteriuria was identified in 96 (82%) patients. Age, sex, activity, diabetes mellitus, mental status, presence of other diseases, catheter material type, catheter size and fixation, hand washing (care giver), gloving (care giver), perineal care, and bladder irrigation were not recognized as risk factors for CAUTI. Age and catheterization duration were associated with CAUTI. Conclusions: Old age was found to be a risk factor for CAUTI (p=0.048). CAUTI incidence decreased as catheter use exceeded 70 months (p=0.028).

Correlation between Total Sleep Time and Weekend Catch-up Sleep and Obesity based on Body Mass Index : A nationwide cohort study in Korea

  • Choi, Yoon-Hee
    • 대한통합의학회지
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    • 제10권1호
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    • pp.1-11
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    • 2022
  • Purpose : Obesity is a major public health burden in developed countries and a well-known risk factor for cardiovascular disease. Short sleep duration is associated with obesity, as well as diabetes, heart disease and death. In modern society, habitual sleep restrictions seem unavoidable due to social obligations and work schedules along with a tendency toward decreased sleep time. Therefore, the purpose of this study is to examine the effect of differences in sleep time between weekdays and weekends on body mass index (BMI). Methods : This study involved 4,234 Korean adults aged 20 to 64 years based on data obtained from the 7th national health and nutrition examination survey (2016). All subjects were classified into the weekend catch-up sleep group (weekend CUS group). and the non catch-up sleep group (non-CUS group). Results : The longer the average sleep time, the lower was the BMI, and the larger the difference in sleep time between weekdays and weekends, the lower was the BMI. Compared with those with an average sleep time of 8 hours or more, obesity was 1.6-fold higher when the average sleep time was less than 6 hours, and 1.2-fold higher in the case of sleep time of 7 hours or more and less than 8 hours. When the difference in sleep time between weekdays and weekends was 0 or less, more than 0 hours but less than 1 hour, and more than 1 hour and less than 2 hours, the risk of obesity was 1.2-fold, 1.1-fold and 1.1-fold higher, respectively, compared with the risk associated with a sleep time difference of 2 hours or greater between weekdays and weekends. However, the difference was not statistically significant. Conclusion : Short sleep duration is positively associated with obesity. In addition, weekend catch-up sleep affects BMI.

성인의 심혈관계 위험인자를 적용한 고저밀도지단백-콜레스테롤혈증과 건강행태의 관련성 연구 : 국민건강영양조사 제6기 (2013 ~ 2015) 자료 이용 (Relationship between health behaviors and high level of low density lipoprotein-cholesterol applying cardiovascular risk factors among Korean adults: based on the sixth Korea National Health and Nutrition Examination Survey (KNHANES VI), 2013 ~ 2015)

  • 차보경
    • Journal of Nutrition and Health
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    • 제51권6호
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    • pp.556-566
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    • 2018
  • 본 연구는 국민건강영양조사 제6기 (2013 ~ 2015) 원시자료를 이용하여 심혈관계 위험인자를 적용한 고LDL-콜레스테롤혈증과 건강행태의 관련성을 조사하기 위해 수행되었으며, 19세 이상 남자 5,939명, 여자 7,902명의 총 13,841명을 대상으로 하였다. 심혈관계 위험인자는 뇌졸중, 심근경색증 또는 협심증, 당뇨병, 고혈압, 흡연, 저HDL-콜레스테롤 (40 mg/dL 미만), 연령 (남자 45세 이상, 여자 55세 이상), 고HDL-콜레스테롤 (60 mg/dL 이상)을 포함하였다. 뇌졸중이나 심근경색증 또는 협심증은 초고위험군, 당뇨병은 고위험군, 이외 위험인자가 2개 이상은 중등도위험군, 1개 이하는 저위험군으로 구분하였다. 각 위험군 별 목표 수치를 기준으로 한 고LDL-콜레스테롤혈증 유병자는 남자 25.5%, 여자 21.7%이었다. 건강행태와 고LDL-콜레스테롤혈증 유무의 연관성을 복합표본 교차분석으로 분석한 결과, 남녀 모두 연령, 교육수준, 결혼상태, 체질량지수, 탄수화물 에너지 섭취 비율, 지방의 에너지 섭취비율, 포화지방 에너지 섭취비율, n-6 지방산의 에너지 섭취 비율에 따라 고LDL-콜레스테롤혈증 유무는 유의한 연관성이 있었다. 그리고 흡연은 남자에서, n-3계 지방산의 에너지 섭취 비율은 여자에서 고LDL-콜레스테롤혈증 유무와 각각 유의한 연관성이 있었다. 건강행태와 고LDL-콜레스테롤혈증 발생 위험과의 관련성을 확인하기 위해 복합표본 다중 로지스틱 회귀분석을 실시한 결과, 교란인자 보정 후 남자에서는 현재 흡연 (OR: 1.66, 95% CI: 1.40-1.99), 비만 (OR: 1.95, 95% CI: 1.64-2.31) 에서 고LDL-콜레스테롤혈증 유병 오즈비가 유의하게 높았다. 여자의 경우 현재 흡연 (OR: 1.73, 95% CI: 1.19-2.52), 비만 (OR: 1.63, 95% CI: 1.39-1.90)에서 고LDL-콜레스테롤혈증 유병 오즈비가 유의하게 높았고, n-3 지방산 에너지 섭취 비율이 '하'(Q1)에 비해 '중 하' (Q2) (OR: 0.77, 95% CI: 0.62-0.96), '중 상' (Q3) (OR: 0.73, 95% CI: 0.56-0.94), '상' (Q4) (OR: 0.67, 95% CI: 0.51-0.87) 에서 고LDL-콜레스테롤혈증 유병 오즈비가 유의하게 낮았다. 따라서 고LDL-콜레스테롤혈증 개선을 위한 전략 수립에 금연, 정상 체중 유지가 필요하며, 영양소별 적정한 에너지 섭취 비율 유지를 고려해야 한다.

당뇨병이 없는 비만 성인의 hs-CRP 수준과 FBG, Fructosamine 및 HbA1c와의 관련성 (Relationship of the hs-CRP Levels with FBG, Fructosamine, and HbA1c in Non-diabetic Obesity Adults)

  • 오혜종;최철원
    • 대한임상검사과학회지
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    • 제50권2호
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    • pp.190-196
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    • 2018
  • 본 연구는 국민건강영양조사 자료를 이용하여 당뇨병이 없는 성인 4,734명을 대상으로 비만 성인의 hs-CRP와 혈당조절 지표들과의 관련성에 대해 알아보고자 하였다. 연구결과 BMI가 증가할수록 혈당조절지표인 FBG와 fructosamine 및 $HbA_1c$가 증가하였으며, hs-CRP는 비만 군에서 가장 높은 수치를 보였고, 인슐린저항성의 지표인 HOMA-IR도 비만 군에서 통계적으로 유의하게 증가하였다. 또한 hs-CRP 수준을 구분하여 혈당조절지표들과의 관련성을 확인한 결과 hs-CRP가 증가할수록 FBG, fructosamine 및 $HbA_1c$가 증가됨을 확인하였고, 여러 관련 변수를 보정한 후에도 hs-CRP가 증가할수록 FBG, fructosamine 및 $HbA_1c$가 통계적으로 유의하게 증가하였다. 결과적으로 비만과 hs-CRP, 혈당조절지표는 각각에서 연관성을 보여 당뇨병이 없는 성인 중 높은 BMI에서 증가된 hs-CRP에 의해 당뇨병의 주요한 병인인 인슐린 저항성을 증가시켜 혈당조절지표인 FBG, fructosamine 및 $HbA_1c$가 통계적으로 유의하게 증가한 것으로 사료된다. 이에 당뇨병이 없는 성인에서도 올바른 식습관 및 규칙적인 운동으로 비만을 예방하여 당뇨병 발생을 감소시키는 노력이 강구되어야 하겠다.

Repercussions of Breastfeeding by Diabetic Women for Breast Cancer

  • Franca, Eduardo Luzia;Franca-Botelho, Aline Do Carmo;Franca, Juliana Luzia;Ferrari, Carlos Kusano Bucalen;Honorio-Franca, Adenilda Cristina
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권11호
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    • pp.6233-6239
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    • 2013
  • Diabetes represents a serious health problem. In the diabetic state, alterations in metabolism, increased susceptibility to infections and immunological changes occur. The suppression of the immune response has been identified as a relevant factor that contributes to the increase in the rate of infections in these patients. At the same time, breast cancer is the most frequent malignant tumor in women. The molecular and cellular mechanisms underlying cancer development have revealed that immune cells functionally regulate epithelial cancer development and progression. Breastfeeding has been hypothesized to reduce the risk of breast cancer. However, early systematic reviews have not yielded consistent findings for this association. The demand for human milk is increasing due to the promotion and consumer acceptance of the health benefits of consuming a natural product rich in bioactive components. However, due to changes in glucose metabolism, the components of the milk from diabetic women are modified depending on the time of evaluation. In this literature review, we summarize important new findings revealing the paradoxical role of breastfeeding in preventing the onset of breast cancer in diabetic mothers. We hypothesized that the milk component production in diabetic mothers is affected by changes in glucose metabolism. Therefore, adequate maternal glycemic control and an adequate duration of breastfeeding for diabetic mothers are crucial to ensure that the immunity components are able to confer protection against breast cancer.

뇌졸중 위험지표로서의 전해질 수치에 대한 환자;대조군 연구 (Case-Control Study on Electrolytes as a Risk Factor of Stroke)

  • 김민지;강경원;유병찬;최선미;강지선;문승희;이재휘;김윤식;설인찬
    • 동의생리병리학회지
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    • 제22권4호
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    • pp.968-974
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    • 2008
  • This study was aimed to investigate the electrolytes and its relationship with acute stroke patients in each stroke type by case-control study. 217 patients with first-ever acute stroke within 2 weeks as the case group(Cases), 146 people without four major risk factors(hypertension, diabetes mellitus, hyperlipidema and ischemic heart disease) as the healthy control group(Normals), and 160 people as the general control group(Controls) were recruited at the Stroke Medical Center in Daejeon University Oriental Medicine Hospital from july 2005 to march 2007 for this case-control study. We analyzed the odds ratio of electrolytes in binary logistic analysis and evaluated each stroke type and general characteristics such as age, sex etc. The level of sodium(Na+) and potassium(K+) were significantly lower in LAA, SVO type of ischemic stroke and hemorrhagic stroke. But the level of chloride(Cl-) had no significant relation with stroke occurance. In this study we demonstrated that low sodium(Na+) and potassium(K+) have an influence on stoke occurance than chloride(Cl-). And we think that the electrolytes must be considered in risk factors of ischemic stroke in Korean and more prospective studies are needed.

관동맥 우회술의 수술성적-수술전 처치 및 수술수기의 영향에 관한 연구 (Surgical Result of Coronary Artery Bypass Grafting - The Effect of Pre and Intraoperative Procedures)

  • 김영태;홍종면;채헌
    • Journal of Chest Surgery
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    • 제26권2호
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    • pp.141-147
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    • 1993
  • A total of 40 patients having a diagnosis of atherosclerotic coronary arterial disease were analysed on the operative outcomes according to variables as follows: 1) preoperative risk factors such as age, sex, CCS (Canadian Cardiovascular Society) functional class, type of angina, number of diseased vessel, presence of left main coronary artery stenosis, previous history of habitual smoking and presence of other medical diseases (diabetes mellitus, essential hypertension), 2) preoperative management such as intravenous infusion of nitroglycerine, preoperative IABP (intra-aortic balloon pump) support and whether the operation was scheduled as emergency or not, 3) intraoperative variables such as infusion method and composition of cardioplegic solutions, number of distal anastomosis, use of internal mammary artery, total cardiopulmonary bypass time and total cross clamp time. Complications included operative death in 12.5%, perioperative myocardial infarction in 25.0% and perioperative arrhythmia in 17.5%. Nineteen perioperative variables were analyzed to identify risk factors for these end points. For operative death, presence of left main coronary artery stenosis (p = 0.056) and cardiopulmonary bypass time (p = 0.029) were significant in the univariate analysis, but presence of left main coronary artery lesion (p = 0.011, $\chi$$^2$= 6.45) and abscence of preoperative of IABP support (p = 0.069, $\chi$$^2$ = 3.30) were independent predictor in multivariate analysis (stepwise linear logistic regression).

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여성의 개인적 특성과 생활양식요인을 이용한 골량감소 예측모형 (Prediction Model for Reduced Bone mass in Women using Individual Characteristics & Life Style Factors)

  • 이은남;이은옥
    • 근관절건강학회지
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    • 제5권1호
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    • pp.83-109
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    • 1998
  • This study was carried out to identify the Important modifiable risk factors for reduced bone mass and to construct prediction model which can classify women with either low or high bone mass. Through the literature review, individual characteristics such as age, body weight, height, education level, family history, age of menarche, postmenopausal period, gravity, parity, menopausal status, and breast feeding period were identified and factors of life style such as past milk consumption, past physical activity, present daily activity, present calcium intake, alcohol intake, cigarette smoking, coffee consumption were identified as influencing factors of reduced bone mass in women. Four hundred and eighty women aged between 28 and 76 who had given measurement bone mineral density by dual energy x-ray absortiometry in lumbar vertebrae and femur from July to October, 1997 at 4 general hospitals in Seoul and Pusan were selected for this study. Women were excluded if they had a history of any chronic illness such as rheumatoid arthritis, diabetes mellitus, hyperthroidism, & gastrointestinal disorder and any medication such as calcium supplements, calcitonin, estrogen, thyroxine, antacids, & corticosteroids known affect bone. As a result of these exclusion criteria, four hundred and seventeen women were used for analysis. Multiple logistic regression model was developed for estimating the likelihood of the presence or absence of reduced bone mass. A SAS procedure was used to estimate risk factor coefficient. The results are as follows For lumbar spine, the variables significant were age, body weight, menopause status, daily activity, past milk consumption, and past physical activity(p<0.01), while for femoral Ward's triangle, age, body weight, level of education, past milk consumption, past physical activity(p<0.001). Past physical activity, present daily activity and past milk consumption are the most powerful modifiable predictors in vertebrae and femur among the predictors. When the model performance was evaluated by comparing the observed outcome with predicted outcome, the model correctly identified 74.1% of persons with reduced bone mass and 84.5% of persons with normal bone mass in the lumbar vertebrae and 82.9% of persons with reduced bone mass and 75.0% of persons with normal bone mass in the femoral Ward's triangle. On the basis of these results, a number of recommendations for the management of reduced bone mass may be made : First, those woman who are classified as high risk group of the reduced bone mass in the prediction model should examine the bone mineral density to further examine the usefulness of this model. Second, the optimal amount of milk consumption and a regular weight bearing exercise in childhood, adolescence, and early adult should be ensured.

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만성질환자 대상 맞춤형 투약상담 중재 프로그램 시범사업에 대한 평가 (Participants' Evaluation on the Payer-driven Medication Counseling Intervention for Individuals with Chronic Disease)

  • 손현순;장선미;이주연;한은아
    • 한국임상약학회지
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    • 제26권3호
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    • pp.245-253
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    • 2016
  • Objective: This study was conducted to evaluate payer-driven medication adherence intervention program from the patient's and counselor's perspectives. Methods: Target patients for intervention were selected by retrospective adherence measures based on national health insurance claims data for hypertension, diabetes and hyperlipidemia. As a serial intervention for higher risk groups of medication non-adherence, initial direct mailing, the first direct telephone call and the second direct call or a home visit were followed. Interview approach to qualitative inquiry was used to evaluate intervention results. Results: Participants including 4 patients received telephone calls, and 4 National Health Insurance Service staff and 4 pharmacists participated as counselors were interviewed regarding their impression of the intervention program. Three major themes arose: overall perception; necessities; and suggestions for success, of the intervention. Despite short period of intervention, educational intervention by telephone counseling involving pharmacists shows potential to improve self-management of chronic disease, and pharmacist-involvement. But more sophisticated selection of target patients requiring the intervention and complementation of electronic database system would be necessary. In addition, personal disposition of counselor was revealed to be an important factor for achieving successful outcome of intervention. Conclusion: The findings suggest that the individualized counseling intervention would be an efficient option for improved medication adherence. Further researches should include longer periods of interventions, a quantitative analysis using adherence measures based on claims data and consideration of clinical benefits associated with the intervention.