• 한국생물공학회:학술대회논문집
• /
• 2003.04a
• /
• pp.622-624
• /
• 2003

Poly(lactic acid) is a biodegradable themoplastic based on the renewable resources to substitute for petrochemical plastics. Most of PLA is produced by ring opening polymerization from lactide. However, pyrolysis process in the lactide synthesis is expensive, we studied lactide synthetic process for more economical preparation of PLA. In this research was tried to minimize the pyrolysis time, and obtained L-lactide from lactic acid without any catalyst.

• Journal of Photoscience
• /
• v.12 no.2
• /
• pp.63-66
• /
• 2005

The azomethine ylide forming photoreaction has been explored by probing the excited state chemistry of several N-trimethylsilylmethyl substituted cyclic and acyclic imides and amide analogs. N-[(Trimethylsilyl)methyl]-N-mesylbenzamide (5) undergoes the excited state C to O silyl migration reaction to produce azomethine ylide intermediate 13. This ylide undergoes electrocyclization to form transient aziridine intermediate 14 which react further by ring opening to generate N-phenacylamine product 10. On the other hand, photolysis of N-[N-mesyl-N-(trimethylsilyl)methyl]aminoethyl-N-mesylbenzamide (8) brings about desilylation resulting in the production of dimer 17.

• Archives of Pharmacal Research
• /
• v.12 no.4
• /
• pp.300-305
• /
• 1989

The synthetic study of 3' azido and 3'-fluoro secouridines toward development of new antiviral agents is described. These acyclic nucleosides were synthesized from uridine by the method of ring opening reaction of sugar moiety.

• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.408.2-409
• /
• 2002

The aim of this study is to prepare biodegradable microspheres without use of any kind of surfactants or emulsifiers for a novel sustained delivery carriers of protein drugs. Poly(e-caprolactone)/poly(ethylene glycol)/poly(e-caprolactone) (CEC) triblock copolymer was synthesized by ring-opening of e-caprolactone with dihydroxy poly(ethylene glycol) and was used to make surfactant-free microspheres. (omitted)

• Bulletin of the Korean Chemical Society
• /
• v.35 no.3
• /
• pp.699-700
• /
• 2014

• Archives of Pharmacal Research
• /
• v.14 no.2
• /
• pp.143-146
• /
• 1991

A new synthetic sequence for the chiral lactone moiety of compactin was developed from $\alpha$-D-glucose in 9 steps via simultaneous reductive detosylation and epoxide-ring opening of 2, 3-epoxy-4-tosylate using NaBH_4$ to afford 2, 4-dideoxy sugar as a key intermediate.

• Bulletin of the Korean Chemical Society
• /
• v.31 no.6
• /
• pp.1732-1734
• /
• 2010

• Journal of the Korean Chemical Society
• /
• v.56 no.3
• /
• pp.322-327
• /
• 2012

Rapid and efficient synthesis of substituted 3-carboxylquinoline derivatives from 4-chloro-3-formylcoumarin and substituted anilines using 30% $H_2SO_4$ in methanol at room temperature within the duration of 5-30 min., through domino condensation-cyclization-ring opening reaction.

• Bulletin of the Korean Chemical Society
• /
• v.33 no.12
• /
• pp.4191-4193
• /
• 2012

• Macromolecular Research
• /
• v.15 no.5
• /
• pp.393-395
• /
• 2007