• Title/Summary/Keyword: retardation function

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Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome: Successful treatment of the first case with bilateral Wilms' tumors in Korea (윌름즈 종양, 무홍체증, 비뇨생식기계 기형, 정신지체 (WAGR) 증후군 : 양측성 윌름즈 종양을 성공적으로 치료한 국내 첫 증례 보고)

  • Min, Kyung Sun;Baek, Hee Jo;Han, Dong Kyun;You, Ju Hee;Hwang, Tai Ju;Kwon, Dong Deuk;Kook, Hoon
    • Clinical and Experimental Pediatrics
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    • v.51 no.12
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    • pp.1355-1358
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    • 2008
  • Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome is caused by deletion of chromosome 11p13, including the Wilms' tumor (WT1) and aniridia gene (PAX6) loci. Here, we report the first case of WAGR syndrome in Korea; the patient was a 2-year-old girl with bilateral aniridia from birth who presented with abdominal distention and mental retardation. Cytogenetically, she had deletion of chromosome 11p11.2-13. Bilateral Wilms' tumors were successfully treated by chemotherapy and surgery. She has been tumor-free for 19 months off chemotherapy with preserved renal function.

Motor delay : cerebral palsy (운동발달 장애)

  • Park, Ho Jin
    • Clinical and Experimental Pediatrics
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    • v.49 no.10
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    • pp.1019-1025
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    • 2006
  • Motor delay, when present, is usually the first concern brought by the parents of children with developmental delay. Cerebral palsy that is the most common motor delay, is a nonspecific, descriptive term pertaining to disordered motor function that is evident in early infancy and is characterized by changes in muscle tone, muscle weakness, involuntary movements, ataxia, or a combination of these abnormalities. A wide range of causative disorders and risk factors have been identified for cerebral palsy, and broadly classified into 5 groups; perinatal brain injury, brain injury related to prematurity, developmental abnormalities, prenatal risk factors, and postnatal brain injury. Delay in attaining developmental milestones is the most distinctive presenting complaint in children with cerebral palsy. A detailed history and thorough physical and neurologic examinations are crucial in the diagnostic process. The clinician should be cautious about diagnostic pronouncement unless the findings are unequivocal. Several serial examinations and history review are necessary. All children with cerebral palsy should undergo a neuroimaging study, preferably MRI, because an abnormality is documented on head MRI(89%) and CT(77%). The high incidence rates for mental retardation, epilepsy, ophthalmologic defects, speech and language disorders and hearing impairment make it imperative that all children with cerebral palsy be screened for mental retardation, ophthalmologic and hearing impairments, and speech and language disorders; nutrition, growth, and swallowing also should be closely monitored.

Quantitative analysis of increase in depth of focus using Wigner distribution function (Wigner 분포 함수를 초점 심도 증가의 정량적 해석)

  • 장남영;강호정;은재정;최평석
    • Korean Journal of Optics and Photonics
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    • v.11 no.6
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    • pp.385-389
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    • 2000
  • A phase-retardation function which was derived from Wigner distribution function (WDF) is used to increase a focal depth of a radially symmetric optical system. The WDF for one-dimensional signal is represented as a two-dimensional function of phasespace ($\chi,\zeta$), and a normalized irradiance is described as a form of the Strehl ratio (SR). The increase in the focal depth is accomplished by delivering a shearing tilt a that represents a characteristic of free space propagation with simple manipulation in the WDF space. In this paper we propose a method for evaluating the focal depth quantitatively by representing the phaseretardation function in terms of the focal depth term. In order to verify the validity of the proposed method, we compared the numerically analyzed result with that of J. Sochki's study. study.

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Design of Creep Function for Forklift Automatic Transmission (지게차 자동변속기 저속주행기능 설계)

  • Jung, Gyuhong
    • Journal of Drive and Control
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    • v.18 no.2
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    • pp.46-55
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    • 2021
  • A forklift is a powered industrial vehicle used to lift and move materials over short distances. Nowadays, almost all forklifts are equipped with an automatic transmission due to its improved operator comfort and increased productivity. Thanks to marked improvement of transmission control unit equipped with highly-advanced microcontrollers, recently developed automatic transmission for forklift have various auxiliary functions such as creep, auto retardation, and automatic shift with excellent shift quality. This paper deals with the creep function which enables one to maneuver a forklift at the designated low speed by slip control of clutches. The design of creep function was based on four modes of creep operation depending on the status of the operator's shift lever and accelerator pedal. Control algorithms and control parameters for each mode were designed to achieve the desired static and dynamic performance. Vehicle test for the designed creep function was carried out with an independently developed embedded controller. Test results confirmed good creep speed control without speed error at a steady state with a mild shift shock during mode changes by stepping or releasing the accelerator.

Natural Frequency of 2-Dimensional Heaving Circular Cylinder: Time-Domain Analysis (상하동요하는 2차원 원주의 고유진동수: 시간 영역 해석)

  • Kim, Ki-Bum;Lee, Seung-Joon
    • Journal of the Society of Naval Architects of Korea
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    • v.50 no.4
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    • pp.224-231
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    • 2013
  • The concept of the natural frequency is useful for understanding the characters of oscillating systems. However, when a circular cylinder floating horizontally on the water surface is heaving, due to the hydrodynamic forces, the system is not governed by the equation like that of the harmonic one. In this paper, in order to shed some lights on the more correct use of the concept of the natural frequency, a problem of the heaving circular cylinder is analyzed in the time domain. The equation of motion, an integro-differential equation, was derived following the fashion of Cummins (1962), and its coefficients including the retardation function were obtained using the numerical solution of Lee (2012). The equation was solved numerically, and the experiment was also carried out in the CNU flume. Using our numerical and experimental results, the natural frequency was defined as its average value given by the motion data excluding those of the initial stage. Our results were then compared with those of the existing investigations such as Maskell and Ursell (1970), Ito (1977) and Yeung (1982) as well as the newly obtained results of Lee (2012). Comparison showed that the natural frequency obtained here agrees well with that of Lee (2012), which was found through the frequency domain analysis. It was also shown that the approximation of heaving motion by a damped harmonic oscillation, which was regarded as suitable by most previous investigators, is not physically suitable for the reason that can be clearly shown through comparing the shape of MCFRs(Modulus of Complex Frequency Response). Furthermore, we found that although the previous approximations yield the damping ratio significantly different from our result the magnitude of natural frequency is not much different from our result.

Dynamic Analysis of Floating Bridge Subject to Earthquake Load Considering Multi-Support Excitation (다중지점 가진 효과를 고려한 부유식 교량의 지진응답 해석)

  • 권장섭;백인열;장승필
    • Journal of the Earthquake Engineering Society of Korea
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    • v.8 no.2
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    • pp.27-33
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    • 2004
  • Dynamic response analysis is conducted for a floating bridge subjected to multiple support earthquake excitation. The floating bridge used in this study is supported by discrete floating pontoons and horizontal pretension cables supported at both ends of the bridge. The bridge is modeled with finite elements and the hydrodynamic added mass and added damping due to the surrounding fluid around pontoons are obtained using boundary elements. During the analysis the concept of retardation function is utilized to consider the frequency dependency of the hydrodynamic coefficients. Multiple support excitation is introduced at both ends of the bridge and the time history response is compared to that of a simultaneous excitation. The results show that the multiple support excitation yields larger values in some responses. for example in cable tensions. than the sumultaneous excitation.

Analytical Solutions for a Three-Member Decay Chain of Radionuclides Transport in a Single Fractured Porous Rock (단일균열 다공성암반에서 방사성핵종의 수송에 대한 3단계 붕괴사슬의 해석해)

  • Yu, Young-Woo;Chung, Chang-Hyun;Kim, Chang-Lak
    • Nuclear Engineering and Technology
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    • v.26 no.4
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    • pp.453-460
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    • 1994
  • The migration equation is modified for a three-member decay chain in the fracture and porous matrix Analytical solutions are obtained by utilizing Laplace transform the initial conditions of Delta function and Bateman equation. The concentrations for each nuclide of Np$^{237}$ -U$^{233}$ -Th$^{229}$ and U$^{234}$ -Th$^{230}$ -Ra$^{226}$ chains selected from the 4n+1 and 4n+2 chains are plotted by utilizing analytical solutions in the fracture. Retardation coefficient of the nuclides are obtained using those of the granite. The results indicate that the daughter nuclides such as U$^{233}$ , Th$^{229}$ , Th$^{230}$ and Ra$^{226}$ become important at the far field from the repository though there is very small initial inventory in the waste solid or spent fuel, for they are produced by the mother nuclides decayed in the fracture and porous matrix.

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Free and forced vibration analysis of FG-CNTRC viscoelastic plate using high shear deformation theory

  • Mehmet Bugra Ozbey;Yavuz Cetin Cuma;Ibrahim Ozgur Deneme;Faruk Firat Calim
    • Advances in nano research
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    • v.16 no.4
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    • pp.413-426
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    • 2024
  • This paper investigates the dynamic behavior of a simply supported viscoelastic plate made of functionally graded carbon nanotube reinforced composite under dynamic loading. Carbon nanotubes are distributed in 5 different shapes: U, V, A, O and X, depending on the shape they form through the thickness of the plate. The displacement fields are derived in the Laplace domain using a higher-order shear deformation theory. Equations of motion are obtained through the application of the energy method and Hamilton's principle. The resulting equations of motion are solved using Navier's method. Transforming the Laplace domain displacements into the time domain involves Durbin's modified inverse Laplace transform. To validate the accuracy of the developed algorithm, a free vibration analysis is conducted for simply supported plate made of functionally graded carbon nanotube reinforced composite and compared against existing literature. Subsequently, a parametric forced vibration analysis considers the influence of various parameters: volume fractions of carbon nanotubes, their distributions, and ratios of instantaneous value to retardation time in the relaxation function, using a linear standard viscoelastic model. In the forced vibration analysis, the dynamic distributed load applied to functionally graded carbon nanotube reinforced composite viscoelastic plate is obtained in terms of double trigonometric series. The study culminates in an examination of maximum displacement, exploring the effects of different carbon nanotube distributions, volume fractions, and ratios of instantaneous value to retardation times in the relaxation function on the amplitudes of maximum displacements.

Myoclonus Induced by the Use of Gabapentin

  • Cho, Keun-Tae;Hong, Seung-Koan
    • Journal of Korean Neurosurgical Society
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    • v.43 no.5
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    • pp.237-238
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    • 2008
  • Myoclonus is a rare side effect of gabapentin (GBP) and has been reported in patients with preexisting myoclonus, mental retardation, chronic static encephalopathy, diffuse brain damage, impaired renal function, or end stage renal disease. We report a case of myoclonus in a patient with normal renal function and no previous disorders. A 69-year-old female underwent diskectomy and foraminotomy at the left L4-L5 level. Post-operatively, she complained of paresthesia in her left leg, which was thought to be due to root manipulation during surgery. To relieve the paresthesia, she was given tramadol, an oral opioid agonist, and GBP. One week after GBP was increased to 900 mg per day, myoclonus developed, which severely impaired her normal activity. Her symptoms resolved 2 days after discontinuation of GBP. The coadministration of tramadol and GBP may mutually enhance the myoclonic potential of each drug. The causal relationship between GBP and myoclonus was suggested by cessation of myoclonus after GBP discontinuation despite continued therapy with tramadol.

Behavior of Retrogradation Retardation in Rice Starch Paste by Raw Wheat Flour Addition (생밀가루 첨가에 따른 쌀전분 페이스트의 노화지연 연구)

  • Bae, In Young;Lee, Jun Woo;Kim, Hong Sul;Kim, Kyung Mi;Han, Gwi Jung;Kim, Myung Hwan;Jun, Soo Jin;Lee, Hyeon Gyu
    • Korean Journal of Food Science and Technology
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    • v.47 no.6
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    • pp.797-800
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    • 2015
  • The effect of raw wheat flour on starch retrogradation retardation was investigated in a rice starch paste model. Specifically, in terms of amylase activity present in the wheat flour, the retardation effect was investigated depending on reaction temperature (40, 60, and $80^{\circ}C$), incubation time (0, 20, 40, and 60 min), and wheat flour addition levels (0-10%). An increase in wheat flour concentration resulted in a rapid decrease in the elastic modulus (G') as the incubation time increased. The G' changes of the rice starch pastes were furthermore fitted by the first order reaction for the reaction rate estimation on the temperature basis. The experimental reaction rate of the paste sample incubated with 10% wheat flour at $40^{\circ}C$ exhibited good agreement with the predicted value. This result implied that the first order reaction kinetics could be suitable to predict the changes in the G' as a function of incubation temperature and wheat flour concentration.