• Title/Summary/Keyword: response to selection

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Possible Genetic Improvement in Dairy Cattle with Improving Reproductive Rates (젖소에 있어서 개량생산 비율에 의한 유전 개량 효과)

  • ;C.Smith
    • Journal of Embryo Transfer
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    • v.10 no.1
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    • pp.33-44
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    • 1995
  • Genetic changes from improving female's reproductive rate through in vitro fertilization of large number of oocytes were studied. The breeding scheme employed was multiple ovulation and embryo transfer of juveniles and adults. Both balanced and unbalanced matings were examined for the four closed progeny population sizes, 10$^3$, 10$^4$, 105, 106. In balanced matings, all selected sires and dams were mated to each other(cross-classified mating) while unbalanced matings allowed selected dams and sires mated partially, eg. unbalanced matings allowed averages of .5 and .25 progeny per each mating. Various numbers of selected sires and dams were also examined in both balanced and unbalanced matings. In all mating schemes, selection of males and females was restricted to he one from each fullsib family to reduce the rate of inbreeding. The model calculations were deterministic and accounted for the effects of selection and inbreeding on loss of the genetic variation in succeeding generations. Balanced rectangular mating schemes, where more donors were selected than sires, resulted in larger selection responses than balanced square mating schemes, where equal numbers of sires and donors were selected, and unbalanced rectangular mating. The first round selection responses from the balanced rectangular matings of juvenile MOET, eg. number of progeny per mating equals 2 with 10 sires selected, were 1.192, 1.406, 1.580 and 1.735 times larger than the first round selection responses from the balanced square mating schemes for the given four progeny population sizes, 10$^3$, 10$^4$, 105 and 106, respectively. Similar results were obtained in adult MOET breeding schemes. However, balanced square matings gave greater selection responses than the unbalanced rectangular matings.

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A Case Study of the Result Analysis of Selection Test Items of Gifted Children in mathematics (초등수학영재 선발시험 문항의 결과 분석에 관한 사례 연구)

  • Ryu, Sung-Rim
    • Communications of Mathematical Education
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    • v.23 no.2
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    • pp.349-381
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    • 2009
  • The purpose of this study is to propose issues in selecting gifted children in mathematics by in-depth analysis of the selection process and items. In order to accomplish the purpose, the rate of right and wrong answers were examined based on the reaction of the students by 1st, 2nd and 3rd selection test. Also, the types of the errors were identified for the 2nd and 3rd selection test. According to the study results, the rate of right answers was low in short response questions and essay questions rather than in multiple-choice questions. In addition, the academic achievements were lower in the fields other than number & operations and logic. The conclusion of this study is that following studies regarding selection of gifted children are required linked with the project tasks and programs.

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A Study on the Fashion Involvement, Clothing Selection Criteria and Fashion Information Sources of Leisure Activities Consumers (여가활동 소비자의 패션관여와 의복선택기준, 패션정보원에 관한 연구)

  • Je, Eun-Suk
    • Journal of the Korean Society of Costume
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    • v.61 no.7
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    • pp.51-66
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    • 2011
  • The study is intended to suggest the differentiated and subdivided indexes of the leisure fashion market and to provide the marketing strategy establishment and in-depth understanding of leisure fashion business by looking into the correlation between and among fashion involvement, clothing selection criteria and fashion information sources. This study was conducted by the questionnaire response method and the results were derived by using the SPSS 16.0 statistics program. The results of the study were as follows; 1) As a result of researching the difference between the leisure activities consumer groups and fashion involvement, there were significant differences in emotional and cognitive involvement. In the tour activity group and social activity group, emotional involvement was found to be higher than the cognitive experience while in the hobby and sports activity group, both involvements were equally as high. 2) As a result of researching the difference between the leisure activities groups and clothing selection criteria, it was found that the intrinsic and extrinsic criteria were high in the hobby and sports activity group and that the intrinsic criteria was high in the tour activity group and social activity group. 3) In the difference between the leisure activity groups and fashion information sources, it was found that media source, observation source and experience/personal source were high in the hobby and sports activity group. In addition, the experience and personal source were high in the social activity group. 4) In the difference between and among fashion involvement, clothing selection criteria and fashion information sources, it was found that the emotional involvement, intrinsic criteria and observation source were higher in the group of females than males. 5) In the difference between and among fashion involvement, clothing selection criteria and fashion information sources depending on the ages of leisure activities consumers, it was found that the emotional involvement and observation source were high in the group of 20-24 yrs old consumers and that the emotional involvement, intrinsic criteria and observation source were high in the group of 25-29 yrs old consumers. Also, in the group of 30-34 yrs old consumers, the emotional involvement, observation source and experience/personal source were high.

Seismic response of active or semi active control for irregular buildings based on eigenvalues modification

  • Pnevmatikos, Nikos G.;Hatzigeorgiou, George D.
    • Earthquakes and Structures
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    • v.6 no.6
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    • pp.647-664
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    • 2014
  • A reduction of the response of irregular structures subjected to earthquake excitation by control devices equipped by suitable control algorithm is proposed in this paper. The control algorithm, which is used, is the pole placement one. A requirement of successful application of pole placement algorithm is a definition-selection of suitable poles (eigen-values) of controlled irregular structures. Based on these poles, the required action is calculated and applied to the irregular structure by means of control devices. The selection of poles of controlled irregular structure, is a critical issue for the success of the algorithm. The calculation of suitable poles of controlled irregular structure is proposed herein by the following procedure: a fictitious symmetrical structure is considered from the irregular structure, adding vertical elements, such as columns or shear walls, at any location where is necessary. Then, the eigen-values of symmetrical structure are calculated, and are forced to be the poles of irregular controlled structure. Based on these poles and additional damping, the new poles of the controlled irregular structure are calculated. By pole placement algorithm, the feedback matrix is obtained. Using this feedback matrix, control forces are calculated at any time during the earthquake, and are applied to the irregular structure by the control devices. This procedure results in making the controlled irregular structure to behave like a symmetrical one. This control strategy can be applied to one storey or to multi-storey irregular buildings. Furthermore, the numerical results were shown that with small amount of control force, a sufficient reduction of the response of irregular buildings is achieved.

Study on the Applicability of Standard Design Response Spectrum Analysis Method for Pile-type Mooring Facilities (말뚝식 계류시설의 표준설계응답스펙트럼 해석법 적용성 연구)

  • Oh, Jeong-Keun;Jeong, Yeong-Seok;Kwon, Min-Ho
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.24 no.5
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    • pp.27-36
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    • 2020
  • The purpose of this paper is to study on the applicability of the standard design response spectrum from the response spectrum analysis method, mainly applied to pile mooring facilities. To this end, after performing the ProShake 1-dimensional site response considering various geological conditions, the current standard design response spectrum was compared, and the ground-pile model in time history and two-dimensional site response analysis using Abaqus were performed to analyze the dynamic behavior of the ground-pile and to examine the selection method of the reference surface of the response spectrum on the installed slope, respectively. As a result, it was confirmed that no problems were found in the applicability of the current standard design response spectrum and no improvements are needed as well when considering the characteristics of the ground-pile dynamic behavior and the slope of the pile mooring facility.

Clinical Application of the Adenosine Triphosphate-based Response Assay in Intravesical Chemotherapy for Superficial Bladder Cancer

  • Ge, Wen-Qing;Pu, Jin-Xian;Zheng, Shi-Ying
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.689-692
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    • 2012
  • Objective: To investigate correlations between adenosine triphosphate chemotherapy response assay (ATP-CRA) and clinical outcomes after ATP-CRA-based chemotherapy for drug selection in patients receiving intravesical chemotherapy to prevent recurrence of superficial bladder cancer after surgery. Methods: The chemosensitivities of 12 anticancer drugs were evaluated, including 5-Fu ADM, and EPI, using ATP-CRA and primary tumor cell culture in 54 patients. In addition, a further 58 patients were treated according to clinical experience. Differences in post-chemotherapeutical effects between drug sensitivity assay and experience groups were compared. Results: The evaluable rate of the test was 96.3%, the clinical effective rate was 80.8%, the sensitivity rate was 97.6% (41/42), the specificity was 20%, the total predicting accuracy was 74.3%, the positive predictive value was 83.7% (41/49), the negative predictive value was 66.7% (2/3); in the drug sensitivity test group, the clinical effective rate was 80.8%, the experience group response rate was 63.8%, with a significant difference in clinical effects between the ATP-based sensitivity and experience groups (${\chi}^2$=7.0153, P<0.01). Conclusion: ATP-CRA is a stable, accurate and potentially practical chemosensitivity test providing a predictor of chemotherapeutic response in patients with superficial bladder cancer.

Parameter Optimization of a Micro-Static Mixer Using Successive Response Surface Method (순차적 반응표면법을 이용한 마이크로 정적 믹서의 최적설계)

  • Han, Seog-Young;Maeng, Joo-Sung;Kim, Sung-Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.28 no.9
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    • pp.1314-1319
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    • 2004
  • In this study, parameter optimization of micro-static mixer with a cantilever beam was accomplished for maximizing the mixing efficiency by using successive response surface approximations. Variables were chosen as the length of cantilever beam and the angle between horizontal and the cantilever beam. Sequential approximate optimization method was used to deal with both highly nonlinear and non-smooth characteristics of flow field in a micro-static mixer. Shape optimization problem of a micro-static mixer can be divided into a series of simple subproblems. Approximation to solve the subproblems was performed by response surface approximation, which does not require the sensitivity analysis. To verify the reliability of approximated objective function and the accuracy of it, ANOVA analysis and variables selection method were implemented, respectively. It was verified that successive response surface approximation worked very well and the mixing efficiency was improved very much comparing with the initial shape of a micro-static mixer.

Seismic Safety Assessment of Containment Building (격납건물의 내진안전성 평가)

  • Lee, Seong-Lo;Bae, Yong-Gwi
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.8 no.3
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    • pp.225-233
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    • 2004
  • In this study, the seismic safety of containment building is assessed using response surface method. The structural analyses considering random variables such as load, resistance and analysis by ABAQUS are performed to obtain the structural response. The structural response is represented by polynomial of random variables, and the reliability analysis is performed by Level II method. Drucker-Prager failure criterion is applied as limit state function to take bi-axial stress states into account in the concrete. The lifetime probability of failure is evaluated by considering the lifetime of containment building, the annual occurrence rate of earthquake and the conditional probability of failure. Also the sensitivity analysis on the selection of sampling points is performed to obtain the steady results from response surface method.

Genetic Relationships of Carcass Traits with Retail Cut Productivity of Hanwoo Cattle

  • Koh, Daeyoung;Lee, Jeongkoo;Won, Seunggun;Lee, Chaeyoung;Kim, Jongbok
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.10
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    • pp.1387-1393
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    • 2014
  • This study aimed to estimate genetic correlation between carcass grading and retail productivity traits and to estimate the correlated response on retail productivity traits through selection for carcass grading traits in order to assess the efficacy of indirect selection. Genetic parameters were estimated with the data from 4240 Hanwoo steers using mixed models, and phenotypes included carcass weight (CWT), back fat thickness (BFT), eye muscle area (EMA), marbling (MAR), and estimated lean yield percentage (ELP) as the carcass grading traits, and weight and portion of retail cuts (RCW and RCP), trimmed fats (TFW and TFP) and trimmed bones (TBW and TBP) as the lean productivity traits. The CWT had positive genetic correlations with RCW (0.95) and TFW (0.73), but its genetic correlation with RCP was negligible (0.02). The BFT was negatively correlated with RCP (-0.63), but positively correlated with TFW and TFP (0.77 and 0.70). Genetic correlations of MAR with TFW and TFP were low. Among the carcass grading traits, only EMA was positively correlated with both RCW (0.60) and RCP (0.72). The EMA had a relatively strong negative genetic correlation with TFW (-0.64). The genetic correlation coefficients of ELP with RCP, TFW, and TFP were 0.76, -0.90, and -0.82, respectively. These correlation coefficients suggested that the ELP and EMA might be favorable traits in regulating lean productivity of carcass.

Homogenized limit analysis of masonry structures with random input properties: polynomial Response Surface approximation and Monte Carlo simulations

  • Milani, G.;Benasciutti, D.
    • Structural Engineering and Mechanics
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    • v.34 no.4
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    • pp.417-447
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    • 2010
  • The uncertainty often observed in experimental strengths of masonry constituents makes critical the selection of the appropriate inputs in finite element analysis of complex masonry buildings, as well as requires modelling the building ultimate load as a random variable. On the other hand, the utilization of expensive Monte Carlo simulations to estimate collapse load probability distributions may become computationally impractical when a single analysis of a complex building requires hours of computer calculations. To reduce the computational cost of Monte Carlo simulations, direct computer calculations can be replaced with inexpensive Response Surface (RS) models. This work investigates the use of RS models in Monte Carlo analysis of complex masonry buildings with random input parameters. The accuracy of the estimated RS models, as well as the good estimations of the collapse load cumulative distributions obtained via polynomial RS models, show how the proposed approach could be a useful tool in problems of technical interest.