• 대한핵의학회지
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• 제14권1호
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• pp.17-21
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• 1980

TRH stimulation tests and $T_3$ suppression tests were done in 13 patients with clinically suspected mild or early hyperthyroidism who were all conventional thyroid function tests gave results within the accepted normal range. The results were as follows 1. 6 patients with normal $T_3$ suppression test revealed normal TRH stimulation test and could be easily diagnosed as euthyroidism. 2. 7 patients with abnormal $T_3$ suppression test exhibited no TSH response to TRH stimulation test and could be easily diagnosed as hyperthyroidism. The TRH stimulation test is a single, sensitive and reliable test of thyroid function and can well replace $T_3$ suppression test in the diagnosis of marginal hyperthyroidism.

• Smart Structures and Systems
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• 제20권6호
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• pp.657-668
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• 2017

In this research, an active vibration suppression of a smart beam having piezoelectric sensor and actuators is investigated by designing separate controllers comprising a linear quadratic regulator and a neural network. Firstly, design of a smart beam which consists of a cantilever aluminum beam with surface bonded piezoelectric patches and a designed mechanism having a micro servomotor with a mass attached arm for obtaining variations in the frequency response function are presented. Secondly, the frequency response functions of the smart beam are investigated experimentally by using different piezoelectric patch combinations and the analytical models of the smart beam around its first resonance frequency region for various servomotor arm angle configurations are obtained. Then, a linear quadratic regulator controller is designed and used to simulate the suppression of free and forced vibrations which are performed both in time and frequency domain. In parallel to simulations, experiments are conducted to observe the closed loop behavior of the smart beam and the results are compared as well. Finally, active vibration suppression of the smart beam is investigated by using a linear controller with a neural network based adaptive element which is designed for the purpose of overcoming the undesired consequences due to variations in the real system.

• 약학회지
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• 제39권6호
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• pp.585-592
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• 1995

Soil microorganisms producing immunomoduators that can restore ultraviolet B (UVB) radiation-induced suppression of the immune response were screened in vitro. Exposure of freshly isolated murine epidermal cells (EC) to $180{\;}J/m^{2}$ of UVB radiation resulted in approximately 90% impairtnent of accessory cell function, as measured by their ability to support anti-CD3 monoclonal antibody-induced T-cell mitogenesis. When the culture supenmtants of 150 actinomycete strains were exanuned for their capacity to prevent or repair the UVB-induced impairment of accessory cell function, 4 of them were identified to contain immunomodulators that can restore the decreased accessory cell finiction. The soil isolate that showed the most effective restorative activity, G40025. was selected and fturther characters Addition of 10.mu.l of the culture supernatant of G40025 grown in G-media to cultures of UVB-irradiated EC right after UVB-irradiation restored the decreased accessory cell function by 58%. The immunomodtdator produced by G40025 appeared to be stable at 100.deg. C for 10 min. Taxonomical studies by cultural, morphological, and physiological characterization showed that the soil isolate, G40025, belongs to the genus Streptomyces.

• Structural Engineering and Mechanics
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• 제89권6호
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• pp.549-556
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• 2024

A serial pendulum dynamic vibration absorber (DVA) was designed to suppress the vibration of two degrees of freedom (Two-DOF) structure model. The optimal DVA parameters are selected using a genetic algorithm (GA) by minimizing the fitness function formulated from the system's frequency response function (FRF). Two fitness function criteria, using one and two target frequency ranges, were utilized to calculate the optimal DVA parameters. The optimized serial pendulum DVA parameters were used to reduce structural vibration under free and forced excitation conditions. The simulation study found that the serial pendulum DVA can effectively reduce the vibration response for a small excitation amplitude. However, the DVA performance decreases for a large excitation amplitude due to the nonlinearity of pendulum motion, and the percentage of vibration response attenuation is smaller than that obtained using a small excitation amplitude.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2004년도 추계학술발표대회 논문집
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• pp.282-285
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• 2004

The main purpose of this study is the vibration suppression of rotating composite blade containing distributed piezoelectric sensors and actuators. The blade is modeled by thin-walled, single cell composite beam including the warping function, centrifugal force, Coriolis acceleration and piezoelectric effect. Further, the numerical study is performed m ing finite element method. The vibration of composite rotor is suppressed by piezocomposite actuators and PVDF sensors that are embedded between composite layers. A velocity feedback control algorithm coupling the direct and converse piezoelectric effect is used to actively control the' dynamic response of an integrated structure through a closed control loop. Responses of the rotating blade are investigated. Newmark time integration method is used to calculate the time response of the model. In the numerical simulation, the effect of parameters such as rotating speed, fiber orientation of the blade and size of actuators are studied in detail.

• Earthquakes and Structures
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• 제7권6호
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• pp.1025-1044
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• 2014

In this paper, a systematic technique is proposed for the optimal placement and design of nonlinear dampers for building structures. The concept of Output Frequency Response Function (OFRF) is applied to analytically represent the output frequency response of a building frame where nonlinear viscous dampers are fitted for suppression of vibration during earthquakes. An effective algorithm is derived using the analytical representation to optimally determine the locations and parameters of the nonlinear dampers. Various numerical examples are provided to verify the effectiveness of the optimal designs. A comparison of the vibration suppression performance with that of the frame structure under a random or uniform damping allocation is also made to demonstrate the advantages of the new designs over traditional solutions.

• 한국추진공학회지
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• 제11권5호
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• pp.23-30
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• 2007

PSD(pogo suppression device)는 액체 추진 로켓의 추진제 공급부를 모사한 배관 시스템에 대한 기존의 실험 연구를 통해 배관 시스템의 동특성을 변화시킬 수 있음을 확인할 수 있었다. 본 연구에서는, PSD에 대한 수학적 모델을 만들고, 각 변수에 대한 값을 결정하는 과정에서 이론적으로 구하기 힘든 변수를 파악하여, 이를 기존의 실험 결과로부터 구하고자 하였다. 그를 위해, 선형화된 전달함수를 만들어 전체 시스템에 대한 불안정성을 판단하는 방법에 대해, PSD를 유체 섭동에 대한 연속 방정식 등의 지배 방정식을 이용하여, 제작된 PSD의 실제 적용시 중요한 이너턴스, 컴플라이언스, 레지스턴스 등의 변수를 수식화하고, 실험 결과를 이용하여 이를 정량화 하는 방법을 제시하였다.

• Wind and Structures
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• 제10권1호
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• pp.1-22
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• 2007

The suppression of aerodynamic response of long-span suspension bridges during erection and after completion by using single TMD and multi TMD is presented in this paper. An advanced finite-element-based aerodynamic model that can be used to analyze both flutter instability and buffeting response in the time domain is also proposed. The frequency-dependent flutter derivatives are transferred into a time-dependent rational function, through which the coupling effects of three-dimensional aerodynamic motions under gusty winds can be accurately considered. The modal damping of a structure-TMD system is analyzed by the state-space approach. The numerical examples are performed on the Akashi Kaikyo Bridge with a main span of 1990 m. The bridge is idealized by a three-dimensional finite-element model consisting of 681 nodes. The results show that when the wind velocity is low, about 20 m/s, the multi TMD type 1 (the vertical and horizontal TMD with 1% mass ratio in each direction together with the torsional TMD with ratio of 1% mass moment of inertia) can significantly reduce the buffeting response in vertical, horizontal and torsional directions by 8.6-13%. When the wind velocity increases to 40 m/s, the control efficiency of a multi TMD in reducing the torsional buffeting response increases greatly to 28%. However, its control efficiency in the vertical and horizontal directions reduces. The results also indicate that the critical wind velocity for flutter instability during erection is significantly lower than that of the completed bridge. By pylon-to-midspan configuration, the minimum critical wind velocity of 57.70 m/s occurs at stage of 85% deck completion.

• Environmental Analysis Health and Toxicology
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• 제4권1_2호
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• pp.67-73
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• 1989

Recently pathotoxicological study of lymphoid organs by administration of some phthalate ester in rats, indicated marked effect of architechure of thymus, spleen, and lymphonodes. Dioctyl phthalate (DOP), one of the phthalate ester, caused statistically significant reduction in the weights of various lymphoid organs. This senstivity of the lymphoid organ to phthalate toxicity which could lead to adverse effects on the immune response and also suppression of immune system. Therfore it is possible the presense of di-(2-ethylhexyl) phthalate (DEHP), one of the phthalate ester as well as DOP, in spleen and other organs might have some moderately effect on the function of the immune system, So our present study was proceeded to assess the effect of DEHP on the immunotoxicity in mouse. In the immune response of DEHP administered mice, HA, HY, Arthus reaction and Rosette forming cell were decreased but DTH was increased. Furthermore, in the DEHP plus ethanol group, HA, HY, Arthus reaction and Rosette forming cell were remarkably decreased and elevation of DTH was inhibited.

• Journal of electromagnetic engineering and science
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• 제11권2호
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• pp.105-112
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• 2011

In phase-locked frequency synthesizers, a fast-lock technique is frequently employed to overcome the trade-off between a lock-time and a spurious response. The function of fast-lock in a conventional PLL (Phased Lock Loop) IC (Integrated Circuit) is limited by a factor of 16, which is usually implemented by a scaling of charge pumper, and consequently a lock time improvement of a factor of 4 is possible using the conventional PLL IC. In this paper, we propose a novel external active fast-lock loop filter. The proposed loop filter provides, conceptually, an unlimited scaling of charge pumper current, and can overcome conventional trade-off between lock-time and spur suppression. To demonstrate the validity of our proposed loop-filter, we fabricated an X-band frequency synthesizer using the proposed loop filter. The loop filter in the synthesizer is designed to have a loop bandwidth of 100 kHz in the fast-lock mode and a loop bandwidth of 5 kHz in the normal mode, which corresponds to a charge pumper current change ratio of 400. The X-band synthesizer shows successful performance of a lock-time of below 10 ${\mu}sec$ and reference spur suppression below -64 dBc.