• Title/Summary/Keyword: respiration measurement

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Estimation of baroreflex sensitivity using pulse arrival time rather than systolic blood pressure measurement

  • Lee, Jong-Shill;Chee, Young-Joon
    • Journal of Biomedical Engineering Research
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    • v.31 no.1
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    • pp.14-19
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    • 2010
  • Baroreflex sensitivity (BRS) is a parameter of the cardiovascular system that is reflected in changes in pulse interval (PD and systolic blood pressure (SBP). BRS contains information about how the autonomic nervous system regulates hemodynamic homeostasis. Normally the beat-to-beat SBP measurement and the pulse interval measured from the electrocardiogram (ECG) are required to estimate the BRS. We investigated the possibility of measuring BRS in the absence of a beat-to-beat SBP measurement device. Pulse arrival time (PAT), defined as the time between the R-peak of the ECG and a single characteristic point on the pulse wave recorded from any arterial location was measured by photoplethysmography. By comparing the BRS obtained from conventional measurements with our method during controlled breathing, we confirmed again that PAT and SBP are closely correlated, with a correlation coefficient of -0.82 to -0.95. The coherence between SBP and PI at a respiration frequency of 0.07-0.12 Hz was similar to the coherence between PAT and PI. Although the ranges and units of measurement are different (ms/mmHg vs. ms/ms) for BRS measured conventionally and by our method, the correlation is very strong. Following further investigation under various conditions, BRS can be reliably estimated without the inconvenient and expensive beat-to-beat SBP measurement.

A Six-port Bio Radar System for Non-Contact Measurement of Heart and Respiration (호흡 및 심박수 측정을 위한 비 접촉방식의 6-포트 바이오레이더 시스템)

  • Na, Won;Lee, Moon-Que
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.1393-1394
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    • 2008
  • 본 논문은 사람의 호흡과 심박 수를 0.5 m 의 거리에서 원격 측정하는 레이더 시스템 설계에 관한 내용을 기술한다. 기존에 많이 사용되었던 능동 주파수 혼합기 회로를 파형 간섭 효과를 이용한 6 -포트 회로로 대치하여 설계하였으며 특히 전력 검출기 성능에 따라 낮은 국부 발진기 전력을 사용할 수 있다는 장점을 가짐을 보였다. 본 논문에서는 수신신호 감지를 위한 최적의 국부 발진기의 전력을 제시하였다.

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Noise Analysis and Measurement for a CW Bio-Radar System for Non-Contact Measurement of Heart and Respiration Rate (호흡 및 심박수 측정을 위한 비접촉 방식의 CW 바이오 레이더 시스템의 잡음 분석 및 측정)

  • Jang, Byung-Jun;Yook, Jong-Gwan;Na, Won;Lee, Moon-Que
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.19 no.9
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    • pp.1010-1019
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    • 2008
  • In this paper, we present a noise analysis and measurement results of a bio-radar system that can detect human heartbeat and respiration signals. The noise analysis including various phase noise effects is very important in designing the bio-radar system, since the frequency difference between the received signal and local oscillator is very small and the received power is very low. All of the noise components in a bio-radar system are considered from the point of view of SNR. From this analysis, it can be concluded that the phase noise due to antenna leakage is a dominant factor and is a function of range correlation. Therefore, the phase noise component with range correlation effect, which is the most important noise contribution, is measured using the measurement setup and compared with the calculated results. From the measurement results, our measurement setup can measure a closed-in phase noise of a free-running oscillator. Based on these results, it is possible to design a 2.4 GHz bio-radar system quantitatively which has a detection range of 50 cm and low power of 1 mW without additional PLL circuits.

SOME PHYSIOLOGICAL STUDIES ON THE UTILIZATION OF ORGANIC SUBSTRATES BY EUGLENA GRACILIS VAR. BACILLA 10616 IN LIGHT AND IN DARKNESS ("유-그레나"의 명암배양에 따르는 유기질의 이용과 호흡 및 생장에 대하여)

  • Lee, Min-Jai
    • Journal of Plant Biology
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    • v.2 no.1
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    • pp.1-12
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    • 1959
  • 1) The comparative studies of the quantitative measurement of growth characteristics and utilization of substrates by Euglena gracilis var. bacilla 10616 in the light and in darkness have been carried out. Eodogenous respiration, effect of respiratory inhibitors and responses to the added substrates for the exogenous respiration are also investigated. 2) All cultures are grown in the open air under the continuous illumination of fluorescent light of 3500 lux at room termperature, the growth rate of the culture in the basal medium added 0.5% lactate is found to be the highest. The growth rate decreases successively for the cultures of 0.5% sucinate, 0.5% Na-acetate, 0.5% malate, and control. There is no growth in the basal meidum added 0.5% butyrate and 0.5% hydroquinone. The similar results are obtained for the mentioned cultures in the darkness. However, the growth rate in basal medium added 0.5% glucose and 0.5% sucrose does seem to increase in the darkness unlike the illumination. 3) The endogenous rate of respiration for the organism cultured photosynthetically is about 12.94ul 02/mg/hr, in basal medium and the respiratory quotient is about 0.84. The rate is decreased by starvations to 6.5ul 02/mg/hr, about to a half, but the respiratory quotient does net change. 4) The oxygen consomption during initial 2 hours in suspending solution ranging from pH 4.5 to pH 9.3 is highest at pH 4.5 in which the algae had grown, at pH 5.5 and at pH 6.9. 5) Endogenous respiration of the cells is strongly inhibited by 0.1M of potassium cyanide, malomic acid, sodium fluoride and iodo-acetic acid. It is also strongly inhibited by 0.01M of potassium cyanide. 6) The respiratory response to added substrates for the exogenous respiration in the organism is coincided with the rate in the basal medium added the substrate in light and in darkness, whether the cells are fed or starved. 7) According to the results of this study, there seems to be the flexibility of the interconversion between photosynthesis and chemosynthesis, heterotropic mode of metabolism, in Euglena gracilis var. bacillaris, and that this organism utilizes the lactate most. It also may be suggested that the enayme systems linked in the each steps of Embden-Myerhof-Parnas path way and TCA cycle seem to exist in this organism.

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Analysis of Correlation Coefficient Between Movements of Thoracoabdominal Tumors and External Respiration Using Image Guided Radiotherapy(IGRT) (영상유도 방사선치료장치(IGRT)를 이용한 흉·복부 종양의 움직임과 외부호흡과의 상관관계 분석)

  • Kim, Gha-Jung;Hong, Ju-Youn;Han, Sang-Hyun
    • The Journal of the Korea Contents Association
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    • v.14 no.9
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    • pp.362-370
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    • 2014
  • This study measured and analyzed the correlation coefficient between movements of thoracoabdominal tumors and external respiration in a free-breathing state, using cyberknife image guided radiotherapy(IGRT). This study subjects included a total of 30 patients with lung tumors(n=10), liver tumors(n=10) and pancreatic tumor(n=10) who underwent radiotherapy, and the movements of tumors were analyzed using converted log data of the tumor motion tracking system(MTS). In a free-breathing state, In relation to Peason's correlation coefficient between external respiration and lung tumors in the entire treatment process, the correlation coefficient was 0.646(p<0.05) in the cranio-caudal direction, 0.365(p<0.088) in the left and right direction and 0.196(p<0.115) in the antero-posterior direction. The correlation coefficient of liver tumors was 0.841(p<0.000) in the cranio-caudal direction, 0.346 (p<0.179) in the left and right direction and 0.691(p<0.001) in the antero-posterior direction. The correlation coefficient of Pancreatic tumors was 0.683(p<0.000) in the cranio-caudal direction, 0.397(p<0.006) in the left and right direction and 0.268(p<0.127) in the antero-posterior direction. In conclusion, the measurement findings of thoracoabdominal tumor movement using IGRT would be helpful in determining an accurate target volume. Moreover, the analysis of correlation between external respiration and movements of internal tumors would provide important information to correct movements of tumors for diverse radiotherapy techniques.

Application of a Textile-based Inductive Sensor for the Vital Sign Monitoring

  • Gi, Sun Ok;Lee, Young Jae;Koo, Hye Ran;Khang, Seonah;Kim, Kyung-Nam;Kang, Seung-Jin;Lee, Joo Hyeon;Lee, Jeong-Whan
    • Journal of Electrical Engineering and Technology
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    • v.10 no.1
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    • pp.364-371
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    • 2015
  • In this study, we developed a feasible structure of a textile-based inductive sensor using a machine embroidery method, and applied it to a non-contact type vital sign sensing device based on the principle of magnetic-induced conductivity. The mechanical heart activity signals acquired through the inductive sensor embroidered with conductive textile on fabric were compared with the Lead II ECG signals and with respiration signals, which were simultaneously measured in every case with five subjects. The analysis result showed that the locations of the R-peak in the ECG signal were highly associated with sharp peaks in the signals obtained through the textile-based inductive sensor (r=0.9681). Based on the results, we determined the feasibility of the developed textile-based inductive sensor as a measurement device for the heart rate and respiration characteristics.

Evaluation of sensitivity of soil respiration to temperature in different forest types and developmental stages of maturity using the incubation method

  • Lee, Eun-Hye;Suh, Sang-Uk;Lee, Chang-Seok;Lee, Jae-Seok
    • Journal of Ecology and Environment
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    • v.35 no.1
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    • pp.1-7
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    • 2012
  • To calculate and predict soil carbon budget and cycle, it is important to understand the complex interrelationships involved in soil respiration rate (Rs). We attempted to reveal relationships between Rs and key environmental factors, such as soil temperature, using a laboratory incubation method. Soil samples were collected from mature deciduous (MD), mature coniferous (MC), immature deciduous (ID), and immature coniferous (IC) forests. Prior to measure, soils were pre-incubated for 3 days at $25^{\circ}C$ and 60% of maximum water holding capacity (WHC). Samples of gasses were collected with 0, 2, and 4 h interval after the beginning of the measurement at soil temperatures of 5, 15, 25, and $35^{\circ}C$ (at 60% WHC). Air samples were collected using a syringe attached to the cap of closed bottles that contained the soil samples. The $CO_2$ concentration of each gas sample was measured by gas chromatography. Rs was strongly correlated with soil temperature (r, 0.93 to 0.96; P < 0.001). For MD, MC, ID, and IC soils taken from 0-5 cm below the surface, exponential functions explained 90%, 82%, 92%, and 86% of the respective data plots. The temperature and Rs data for soil taken from 5-10 cm beneath the surface at MD, MC, ID, and IC sites also closely fit exponential functions, with 83%, 95%, 87%, and 89% of the data points, respectively, fitting an exponential curve. The soil organic content in mature forests was significantly higher than in soils from immature forests (P < 0.001 at 0-5 cm and P < 0.005 at 5-10 cm) and surface layer (P = 0.04 at 0-5 cm and P = 0.12). High soil organic matter content is clearly associated with high Rs, especially in the surface layer. We determined that the incubation method used in this study have the possibility for comprehending complex characteristic of Rs.

Measurement of Viable Cell Number in Mixed Culture Based on Microbial Respiration Rate (미생물 호흡속도에 기초한 혼합배양중의 생균수 측정)

  • Veljkoic, V.B;;C.R.Engler
    • Microbiology and Biotechnology Letters
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    • v.20 no.6
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    • pp.687-692
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    • 1992
  • A simple method to determine viable cell numbers of each species in mixed culture was developed. The oxygen uptake rate (OUR) equals to the product of the specific OUR and the size of the microbial population. In a mixed culture, the OUR is a result of the respiration activities of each sub-population. The OUR was determined from the slope of the linear relationship between time and the decrease of dissolved oxygen concentration when aeration was stopped. The specific OUR was calculated from the slope of the viable cell number versus OUR curve. These values for C. lusitaniae at 20 and $30^{\circ}C$ were $1.36{\times}10^{-9}$ and $3.90{\times}10^{-9}$ and those for P tannoPhilus at 20 and $30^{\circ}C$ were $0.59{\times}10^{-9}$ and $1.86{\times}10^{-9}$ [(%/s)/(cells/ml)J. respectively. Using these values, viable cell numbers were calculated after the OURs of mixed culture at two temperatures were measured. A good agreement between the viable cell numbers determined by this method and by plate count was obtained.

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Design of Unconstrained Baby Monitoring System Based on a Doppler Radar and an Air Mattress (도플러 레이더와 에어 매트리스를 이용한 무구속 방식의 신생아 감시 장치 설계)

  • Yang, Seong-Soo;Cho, Sung-Pil;Park, Ho-Dong;Lee, Kyoung-Joung
    • Journal of Biomedical Engineering Research
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    • v.35 no.6
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    • pp.177-184
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    • 2014
  • Continuous monitoring of heart rates and respiratory rates for newborns or infants is very important since the abnormal breathing and heart problems can threaten the life of newborns or infants. A noncontact baby monitoring system based on a Doppler radar and an air mattress was designed. The Doppler radar was used to acquire respiratory signals and the air mattress was employed to obtain heart rates. The performance of the designed system was evaluated using a commercialized infant simulator ($Simbaby^{TM}$) and a respiration belt transducer was used to measure respiration rates as a reference. Results for respiratory rates revealed that the correlation coefficients between I-and Q-channel and the respiration belt were 0.84 and 0.91 and the mean ${\pm}$ standard deviations of errors between them were $1.66{\pm}1.92$ (bpm) and $0.88{\pm}1.65$ (bpm). Heart rates showed that the correlation coefficient between air mattress and set value of the simulator was 0.73 and the mean ${\pm}$ standard deviation of errors between them was $1.09{\pm}3.45$ (bpm). These results indicate that the designed system holds the potential as an effective monitoring tool for continuous monitoring heart rates and respiratory rates of newborns or infants.