• Journal of Radiation Protection and Research
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• 제41권4호
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• pp.339-343
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• 2016

Background: Evaluation of deoxyribonucleic acid (DNA)-strand break is important to elucidate the biological effect of ionizing radiations. The conventional methods for DNA-strand break evaluation have been achieved by Agarose gel electrophoresis and others using an electrical property of DNAs. Such kinds of DNA-strand break evaluation systems can estimate DNA-strand break, according to a molecular weight of DNAs. However, the conventional method needs pretreatment of the sample and a relatively long period for analysis. They do not have enough sensitivity to detect the strand break products in the low-dose region. Materials and Methods: The sample is water, methanol and plasmid DNA solution. The plasmid DNA pUC118 was multiplied by using Escherichia coli JM109 competent cells. The resonance frequency and Q-value were measured by means of microwave dielectric absorption spectroscopy. When a sample is located at a center of the electric field, resonance curve of the frequency that existed as a standing wave is disturbed. As a result, the perturbation effect to perform a resonance with different frequency is adopted. Results and Discussion: The resonance frequency shifted to higher frequency with an increase in a concentration of methanol as the model of the biological material, and the Q-value decreased. The absorption peak in microwave power spectrum of the double-strand break plasmid DNA shifted from the non-damaged plasmid DNA. Moreover, the sharpness of absorption peak changed resulting in change in Q-value. We confirmed that a resonance frequency shifted to higher frequency with an increase in concentration of the plasmid DNA. Conclusion: We developed a new technique for an evaluation of DNA damage. In this paper, we report the evaluation method of DNA damage using microwave dielectric absorption spectroscopy.

• Investigative Magnetic Resonance Imaging
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• 제20권4호
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• pp.207-214
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• 2016

Purpose: The purpose of this study was to investigate the effect of the number of measurement points on the calculation of transverse relaxation time (T2) with a focus on muscle T2. Materials and Methods: This study assumed that muscle T2 was comprised of a single component. Two phantom types were measured, 1 each for long ("phantom") and short T2 ("polyvinyl alcohol gel"). Right calf muscle T2 measurements were conducted in 9 healthy male volunteers using multiple-spin-echo magnetic resonance imaging. For phantoms and muscle (medial gastrocnemius), 5 regions of interests were selected. All region of interest values were expressed as the mean ${\pm}$ standard deviation. The T2 effective signal-ratio characteristics were used as an index to evaluate the magnetic resonance image quality for the calculation of T2 from T2-weighted images. The T2 accuracy was evaluated to determine the T2 reproducibility and the goodness-of-fit from the probability Q. Results: For the phantom and polyvinyl alcohol gel, the standard deviation of the magnetic resonance image signal at each echo time was narrow and mono-exponential, which caused large variations in the muscle T2 decay curves. The T2 effective signal-ratio change varied with T2, with the greatest decreases apparent for a short T2. There were no significant differences in T2 reproducibility when > 3 measurement points were used. There were no significant differences in goodness-of-fit when > 6 measurement points were used. Although the measurement point evaluations were stable when > 3 measurement points were used, calculation of T2 using 4 measurement points had the highest accuracy according to the goodness-of-fit. Even if the number of measurement points was increased, there was little improvement in the probability Q. Conclusion: Four measurement points gave excellent reproducibility and goodness-of-fit when muscle T2 was considered mono-exponential.

• 한국초전도ㆍ저온공학회논문지
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• 제18권1호
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• pp.46-49
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• 2016

The wireless power transfer (WPT) system using a magnetic resonance was based on magnetic resonance coupling of the transmission and the receiver coils. In these system, it is important to maintain a high quality-factor (Q-factor) to increase the transmission efficiency of WPT system. Our research team used a superconducting coil to increase the Q-factor of the magnetic resonance coil in WPT system. When the superconductor is applied in these system, we confirmed that transmission efficiency of WPT system was higher than normal conductor coil through a preceding study. The efficiency of the transmission and the receiver coil is affected by the magnetic shielding effect of materials around the coils. The magnetic shielding effect is dependent on the type, thickness, frequency, distance, shape of materials. Therefore, it is necessary to study the WPT system on the basis of these conditions. In this paper, the magnetic shield properties of the cooling system were analyzed using the High-Frequency Structure Simulation (HFSS, Ansys) program. We have used the shielding materials such as plastic, aluminum and iron, etc. As a result, when we applied the fiber reinforced polymer (FRP), the transmission efficiency of WPT was not affected because electromagnetic waves went through the FRP. On the other hand, in case of a iron and aluminum, transmission efficiency was decreased because of their electromagnetic shielding effect. Based on these results, the research to improve the transmission efficiency and reliability of WPT system is continuously necessary.

• 한국응용과학기술학회지
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• 제30권4호
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• pp.592-601
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• 2013

이 연구는 3-(1,8나프탈이미도)프로필메타아크릴레이트(NIPM)와 GMA공중합체의 합성과 물성에 관한 과제로서 나프탈이미드 발색단을 가진 공중합체의 조성, 모노머 반응성비, 공명효과(Q)와 극성효과 (e), 형광특성 등을 조사하였다. Azobisisobutyronitronitryl(AIBN) 개시제와 dimethylformamide(DMF) 용매를 $60^{\circ}C$에서 공중합하였다. Fineman-Ross(F-R)와 Kelen-$T\ddot{\bar{u}}d\ddot{\tilde{o}}s$(K-T)법으로 부터 단량체 반응성비를 구하였으며, $r_1$값이 $r_2$보다 크게 나타났다. NIPM이 공중합체내에서 GMA보다 더 많음을 알 수 있다. 380 nm에서 약한 분자형광띠와 460 nm에서 강한 중합체 엑시머 형광띠가 나타났다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1767-1772
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• 2008

A microcantilever is a well-known MEMS structure for sensing bio-chemical molecules. When bio-chemical molecules are adsorbed on the microcantilever's surface, resonance frequency shift is generated. There are two issues in this phenomena. The first one is which one between mass change and surface stress change effects is more dominant on the resonance frequency shift. The second one is what will be the performance change when the boundary condition is changed from cantilevers to double clamped beams. We have studied the effect of surface stress change and compared it with that of mass change by using FEM analysis. Furthermore, for microstructures having different boundary conditions, we have studied Q-factor, which determines the detection limit of micro/nano mechanical sensors.

• Journal of Electrical Engineering and Technology
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• 제13권6호
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• pp.2335-2343
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• 2018

This paper proposes an optimal damping control algorithm of the DTI (Direct Two-level Inverter) to miniaturize and reduce the weight of auxiliary power supply for railway vehicles. The conventional auxiliary power supply for railway vehicles uses a DC-DC converter to maintain the inverter input power from the line voltage smoothly. The proposed topology does not use a DC-DC converter for reducing of manufacturing and maintenance costs. It also proposes a DTI topology removed damping resistors that generate ground signal noise in a certain period. At this time, a resonance phenomenon of DC-link voltage occurs due to variation of the inductive load, and a method of controlling the resonance phenomenon of DC-link voltage is required. In order to suppress the resonance phenomenon of the DC-link voltage, at a point before resonance occurs, this paper introduces an algorithm to suppress the resonance phenomenon of DC-link voltage by compensating the resonance component of the q axis voltage of the synchronous reference frame. The proposed algorithm verifies the effect through simulation and experiment.

• 한국자기공명학회논문지
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• 제17권1호
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• pp.40-46
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• 2013

For a case study of suspected paraquat intoxication, we developed a simple and rapid method of $^1H$ qNMR to determine the mili-molar amount of paraquat in postmortem blood samples. There were no interfering signals from endogenous compounds in the chemical shift of paraquat and diquat (internal standard). The amount of sample used ranged from 0.25 mM to 10.0 mM. Diquat, which has similar physicochemical properties with paraquat, was chosen as an internal standard. The NMR experimental conditions, relaxation delay time and CPMG spin-echo pulse sequence were optimized. The developed method was validated in terms of specificity, accuracy, precision, matrix effect, recovery, limit of detection (LOD), and low limit of quantification (LLOQ). The proposed qNMR method provided a simple and rapid assay for the identification and quantification of the quaternary ammonium herbicide, "paraquat" in postmortem blood samples. This method was tested by using the blood from the heart of a man who was intoxicated with paraquat. In this particular case, the level of paraquat was 1.07 mM in the blood. For the determination of quaternary ammonium herbicides, qNMR could also be used to provide a better understanding of the currently available techniques.

• Investigative Magnetic Resonance Imaging
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• 제13권2호
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• pp.171-176
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• 2009

목적 : 자기공명영상 장비에서 신호를 주고 받는 주요 부분인 RF 코일의 성능 특성인 Q 값 (quality factor)과 신호대잡음비 (SNR, signal-to-noise ratio) 값에 미치는 코일 구리선 코팅 재질의 영향을 조사하고자 하였다. 대상 및 방법 : 폴리에스테르 (polyester), 폴리우레탄 (polyurethane), 폴리이미드 (polyimide), 폴리아마이드이미드 (polyamideimide), 폴리에스테르이미드 (polyester-imide)가 코팅된 직경 0.4 mm 구리선을 사용하여, 내경이 1.7mm인 RF 코일을 솔레노이드 형태로 제작한 후 network analyzer로 Q 값을 측정하였다. 또한 제작된 RF 코일을 600 MHz MRI (14.1 T, Bruker DMX600) 장비를 이용하여 표준시료를 이용한 자기공명영상 실험을 수행하였으며, 5개의 다른 코팅 재질과 코팅이 없는 경우에 대하여 영상에서의 신호대잡음비를 비교하였다. 결과 : 코팅 피복을 벗겨내고 측정한 신호대잡음비는 오차 범위에서 유사하였으며, 코팅되어 있는 경우에는 그 재질에 따라 Q 값 및 신호대잡음비가 다르고, 폴리에스테르의 경우를 제외하면 코팅 피복이 없는 경우와 비교하여 큰 값을 보였다. 폴리우레탄 코팅 구리선을 사용하였을 때 Q 값 및 신호대잡음비가 가장 크게 나타났으며, 가장 작은 값을 보인 폴리에스테르 코팅재질인 경우와 비교할 때 신호대잡음비가 34% 정도 큰 값을 보였다. 결론 : 1.2 mm 이하의 작은 생체시료에 적합한 솔레노이드형 RF 코일을 상용 프로브에 장착하여 사용할 수 있도록 손쉽게 제작하였으며, 폴리우레탄으로 코팅된 구리선으로 만들어진 코일의 경우 신호대잡음비가 30% 이상으로 가장 우수한 결과를 보였고, 따라서 코팅 재질의 선택이 자기공명영상의 결과에 중요하게 작용함을 확인할 수 있었다.

• 대한전자공학회논문지SD
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• 제39권4호
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• pp.41-54
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• 2002

본 논문에서는 등가회로를 이용하여 브래그 반사층형 FBAR (Film Bulk Acoustic Wave Resonator) 와 membrane 형 FBAR 그리고 상 하부 전극이 공기와 접하는 이상적인 FBAR 의 특성을 서로 비교함으로서 브래그 반사층과 membrane 이 공진 특성에 미치는 영향을 분석하였다. 압전층으로는 ZnO, membrane 층과 낮은 음향적인 임피던스 반사층은 SiO₂, 높은 음향적인 임피던스 반사층으로는 W, 전극층으로는 Al를 가정하였고 각 층은 탄성파 전달 손실을 가정하였다. 1-port 의 등가회로를 ABCD 파라미터를 추출할 수 있는 단순화된 등가회로로 변환하여 ABCD 파라미터를 추출하여 입력임피던스를 계산하였다. 필터 설계에서는 구하여진 파라미터를 산란행렬로 변환하여 필터의 대역폭 및 삽입손실을 구하였다. 전극층, 반사층, membrane 층의 두께 변화에 의한 공진주파수의 변화는 membrane 층과 전극 바로 아래의 반사층의 두께 변화가 가장 큰 영향을 미친다는 결과를 확인하였다. 반사층 구조에서 반사층수에 따른 공진특성과 K/sub eff/와 electrical Q 의 변화에서는 반사층수가 K/sub eff/ 에는 거의 영향을 미치지 않지만 electrical Q 는 층수가 증가할수록 증가하다가 7층 이상에서 포화되었다. 또한 FBAR의 electrical Q 는 membrane 층과 반사층의 mechanical Q 에 의존함을 알 수 있었다. Ladder 필터와 SCF(Stacked Crystal Filters) 모두 공진기의 수가 증가할수록 삽입손실과 out-of-band rejection 이 증가하였고 층수가 증가할수록 삽입손실은 감소하지만 대역폭에는 거의 변화가 없었다. membrane형의 ladder 필터와 SCF 는 불효 공진 특성으로 인한 불효응답특성이 나타났다. 또한 ladder 필터는 보다 우수한 대역폭의 skirt-selectivity 특성을 나타내었으며 SCF 는 대역폭의 삽입손실 측면에서 더 우수하였다.

• 한국응용과학기술학회지
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• 제30권2호
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• pp.297-304
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• 2013

Free-radical copolymerization of glycidyl methacrylate(GMA) and N-phthalimidoethyl acrylate(NPEA) were carried out at $60^{\circ}C$ in dimethylformamide(DMF) solution in the presence of benzoylperoxide(BPO) at low conversion. The polymers were characterized by IR and $^1H$-NMR. The compositions of the copolymer was analyzed by ultra violet(UV/Vis) spectrophotometry. The reactivity ratios of the monomer was determined by the application of Fineman-Ross(FR) and Kelen-T$\ddot{u}$d$\ddot{o}$s(KT) methods. The monomer reactivity ratios of the system and Alfrey-Price's resonance effect(Q) and polar effect(e) value for NIEA were determined as follow. The reactivity ratios of the monomer obtained from FR and KT are found to be $r_1$=0.87, $r_2$=0.98 and $r_1$=0.88, $r_2$=0.99 respectively. The Q and e values of poly(GMA-co-NPEM) calculated from $r_1$ and $r_2$ was Q= 1.31, e=0.75 respectively.