• 제목/요약/키워드: resistance.

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돼지유래 Salmonella Schwarzengrund의 약제내성 유전자에 관한 연구 (Investigation on antimicrobial resistance genes of Salmonella Schwarzengrund isolated from pigs)

  • 이우원;김상현;이승미;이강록;이기흔;김용환
    • 한국동물위생학회지
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    • 제35권1호
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    • pp.1-8
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    • 2012
  • To detect the virulence genes (invA and spvC) and antimicrobial resistance genes, polymerase chain reaction (PCR) was carried out using total 67 strains of S. Schwarzengrund isolated from pigs. As results, invA was detected from all 67 strains of S. Schwarzengrund, however, spvC was not at all. All 12 strains with ampicillin resistance, 15 strains with chloramphenicol resistance, 9 strains with kanamycin resistance, 1 strain with sulfamethoxazole/trimethoprim resistance, and 66 (98.5%) of 67 strains with tetracycline resistance carried TEM (${\beta}$-lactamase $bla_{TEM}$), cmlA (nonenzymatic chloramphenicol resistance), aphA1-Iab (aminoglycoside phosphotransferase), sulII (dihydropteroate synthase), and tetA (class A tetracycline resistance), respectively. All 63 strains with streptomycin resistance carried 3 aminoglycoside resistance genes, including aadA (aminoglycoside adenyltransferase), strA, and strB (streptomycin phosphotransferase). With respect to prevalence of antibiotic resistance genes occurred in S. Schwarzengrund, genes for strB (46.0%); strA and strB (30.2%); aadA, strA, and strB (9.5%); strA (7.9%); aadA and strB (3.2%); and aadA (3.2%) were detected by PCR.

서해안 수산생물에서 분리한 대장균(Escherichia coli)의 항생제 내성 및 다제 내성 양상 비교 (Comparison of Antimicrobial Resistance and Multi-Drug Resistance Patterns of Escherichia coli Isolated from Aquatic Organisms Off the West Coast of South Korea)

  • 정연겸;박보미;김민주;박진일;정연중;오은경
    • 한국수산과학회지
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    • 제54권4호
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    • pp.388-396
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    • 2021
  • Antimicrobial resistance patterns of Escherichia coli were investigated. Strains were isolated from 310 shellfish, 36 crustaceans, and 12 fish collected off the West Coast of Korea from April 2019 to October 2020. Two hundred and ninety-five E. coli strains were isolated from shellfish, 100 from crustaceans, and 54 from fish. Strains isolated from shellfish showed the highest resistance to ampicillin (27.5%), whereas those from crustaceans were resistant to sulfisoxazole (30.0%) and those from fish were resistant to ampicillin (59.3%) and sulfisoxazole (59.3%). Ceftazidime resistance was observed in strains isolated from short neck and hard clams, whereas gentamicin resistance was observed in strains from fish. Multi-drug resistance was observed in 56 strains (48.7%) isolated from shellfish, 11 (28.2%) from crustaceans and 27 (73.0%) from fish. Depending on the source of isolation, the strains showed specific antimicrobial resistance tendency. Strains isolated from shellfish showed 12 different multi-drug resistance patterns, whereas those from crustaceans showed high resistance (59%) to a single antimicrobial agent and those from fish showed a broad trend of multi-drug resistance to more than eight antimicrobials.

정보기술도입(情報技術導入)에 따른 조직구성원(組織構成員)의 저항(抵抗)에 관한 연구(硏究) (A Study on the Resistance of Individuals in the Organization when Information Technology is introduced)

  • 이재열
    • 경영과정보연구
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    • 제1권
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    • pp.41-73
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    • 1997
  • Responses from the information users on the information technology are very important considerations when majority of the companies are going to introduce information technology by way of computers. When new information technology is introduced, resistance from the information users are likely to be happen and if suitable management about this is not carried out, resistance from the users of information technology will be continued. It is needed for the companies to minimize user's resistance about the information technology to reduce the introduction cost of information technology and to elevate the degree of use. To reduce the resistance from the users about information technology, factors which affect the resistance of users should be analyzed first and it will be effective to control those factors later on. Therefore it will be meaningful for the successful management of information technology if several factors which affect the resistance of users about information technology are searched out and managed. The purpose of this study is to find various factors which affect the resistance of the individuals in the organization about information technology in the process of introducing information technology. The relationship between the factors and factors which affect indirectly to the information technology are the things which are supposed to be considered to the companies who are going to introduce information technology in the long run. Instead of decreasing the resistance directly, let individuals in the organization decreases the resistance by themselves is a more effective way and may have less side effects, in terms of controlling the members in the organization.

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단파장 영역에서 운항 자세가 KCS의 선체 저항에 미치는 영향 (Effects of Trim Conditions on Ship Resistance of KCS in Short Waves)

  • 김연주;이상봉
    • 대한조선학회논문집
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    • 제54권3호
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    • pp.258-266
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    • 2017
  • Numerical simulations of turbulent two phase flows around KCS have been performed to investigate effects of trim conditions on ship resistance of KCS in short waves by utilizing waves2foam. The wave lengths of LPP/2 and LPP/4 with 1m and 2m wave heights were imposed at inlet boundary. The resistance reduction at 2m trim by head and the increase of resistance at trims by stern were observed regardless of wave lengths and wave heights. The hull pressure on fore-and-aft rather than wave patterns around bulbous bows was mainly responsible for the total resistance coefficients of KCS in short waves. A phase diagram of contribution of hull pressure to the total resistance coefficients disclosed that the phase of representing the maximum resistance in time history played an important role in the effect of trim conditions on ship resistance of KCS in short waves.

띠형 섬유보강재의 설치간격에 따른 인발저항 특성에 관한 연구 (Pullout Resistance by Horizontal Spacing of Geosynthetic Strip)

  • 한중근;윤원일;홍기권;이광우;김주형;조삼덕
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2010년도 추계 학술발표회
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    • pp.315-324
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    • 2010
  • In this study, the pullout tests are conducted to evaluate the pullout resistance of the geosynthetic strip with or without bearing resistance zone. The test results are indicated that the pullout resistance of the geosynthetic strip without bearing resistance zone is not affected by horizontal spacing. However, the horizontal spacing of reinforcement with bearing resistance zone affects the bearing resistance. In other words, it is indicated that the bearing resistance at spacing of 210mm is larger than that at spacing of 260mm. This means that the pullout strength at spacing of 210mm is larger than that at spacing of 260mm. Therefore.

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가상현실 모션센싱 입력장치에 대한 혁신 저항과 수용 (Innovation resistance and adoption regarding a virtual reality motion-sensing input device)

  • 박현정;최재원;신경식
    • 지식경영연구
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    • 제16권4호
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    • pp.191-213
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    • 2015
  • With the advancement of virtual reality technology, virtual reality contents and devices are being competitively released. This research deals with an early stage adoption model of a motion-sensing input device which enhances the user experience of these virtual reality contents and devices. In contrast to the previous research on the adoption or resistance of innovative products, this work compares and analyzes the antecedents in MIR(Model of Innovation Resistance) of resistance-perspective as well as those in UTAUT2(Extended Unified Theory of Acceptance and Use of Technology) and IDT(Innovation Diffusion Theory) of adoption-perspective, and suggests a resistance-incorporated adoption model from a new viewpoint. The analysis of questionnaire data indicates the following results: Performance expectancy, effort expectancy, price value, hedonic motivation in UTAUT2 and visibility in IDT have a significant negative influence on innovation resistance. Compatibility in IDT and MIR exerts a positive influence on perceived value. Social influence and hedonic motivation in UTAUT2 positively relates to perceived value. Higher innovation resistance results in lower perceived value, with innovation resistance and perceived value negatively and positively affecting intention to use, respectively.

The relationship between muscle mitochondrial nutritional overloading and insulin resistance

  • Jeon, Jae-Han;Moon, Jun-Sung;Won, Kyu-Chang;Lee, In-Kyu
    • Journal of Yeungnam Medical Science
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    • 제34권1호
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    • pp.19-28
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    • 2017
  • The incidence of type 2 diabetes mellitus and insulin resistance is growing rapidly. Multiple organs including the liver, skeletal muscle and adipose tissue control insulin sensitivity coordinately, but the mechanism of skeletal muscle insulin resistance has not yet been fully elucidated. However, there is a growing body of evidence that lipotoxicity induced by mitochondrial dysfunction in skeletal muscle is an important mediator of insulin resistance. However, some recent findings suggest that skeletal mitochondrial dysfunction generated by genetic manipulation is not always correlated with insulin resistance in animal models. A high fat diet can provoke insulin resistance despite a coordinate increase in skeletal muscle mitochondria, which implies that mitochondrial dysfunction is not mandatory in insulin resistance. Furthermore, incomplete fatty acid oxidation by excessive nutrition supply compared to mitochondrial demand can induce insulin resistance without preceding impairment of mitochondrial function. Taken together we suggested that skeletal muscle mitochondrial overloading, not mitochondrial dysfunction, plays a pivotal role in insulin resistance.

복숭아혹진딧물의 살충제 저항성에 관한 연구 (V). Cypermethrin과 Pirimicarb에 의한 저항성 발달과 교류저항성 (Studies of the Insecticide Resistance in the Green Peach Aphid, Myzus persicae Sulzer (V). Development of Cypermethrin and Pirimicarb Resistance, and Cross Resistance)

  • 최승윤;김길하;안용준
    • 한국응용곤충학회지
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    • 제28권1호
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    • pp.23-27
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    • 1989
  • Pyrethroid계 살충제인 cypermethrin과 carbamate계 살충제인 pirimicarb를 공시하여 실내 감수성계통 복숭아혹진닷물(Myzus persicae)을 인위적으로 루대도태한 후, 저항성 발달속도와 정도를 조사하고, 이들 저항성 계통의 타살충제에 대한 교차저항성 유무와 그 정도를 검토하였다. 저항성 발달속도는 cypermethrin 20세대 도태계통에서 도태전에 비하여 20.5차 증가하였으나, pirimicarb 20세대 도태계통에서는 3.2배 증가에 그쳐 살충제 종류에 따라 큰 차이를 보였다. Cypermethrin 도태계통은 acephate와 pirimicarb에 대해서 , pirimicarb 도태계통은 acephate와 cypermethrin에 대해서 교차저항성을 나타내었다. 그러나 cypermethrin, pirimicarb 도태계통은 demeton-S-methyl에 대해서 비교우저항성을 나타내었다.

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Prevalence of Aspirin Resistance and Clinical Characteristics in Patients with Cerebral Infarction

  • Choi, Jong-Tae;Shin, Kyung-A;Kim, Young-Kwon
    • 대한의생명과학회지
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    • 제19권3호
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    • pp.233-238
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    • 2013
  • Aspirin is still the mainstay of antiplatelet therapy in the cardiovascular and cerebrovascular disease. However, some patients are not responsive to the antithrombotic action of aspirin. The aim of this study was to assess the prevalence and clinical characteristics of aspirin resistance in patients with cerebral infarction. We tested platelet function in 557 patients who had been treated with aspirin in J general hospital. Platelet function was tested using the multiple electrode platelet aggregometry (MEA). Platelet reactivity was expressed as area under the aggregation curve (AUC, U) and >30 AUC was defined as aspirin resistance. Aspirin resistance was detected in 16.2% patients. There was not any significant differences in age, gender between aspirin resistance and aspirin sensitive patients. WBC was significantly higher in patients with aspirin resistance (P < .05). HDL-cholesterol was significantly higher in patients with aspirin sensitive (P < .05). Aspirin resistance was positive correlation with platelet count (r =.314, P =.003). The prevalence of aspirin resistance in cerebral infarction was 16.2%, and platelet count were related with aspirin resistance.

탄소 피막 가변 저항기의 접동 잡음 감소에 관한 연구 (A Study on Decreasing of Sliding Noise of a Carbon Film Variable Resistor)

  • 윤재강
    • 대한전자공학회논문지
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    • 제20권1호
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    • pp.50-54
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    • 1983
  • 민생용 전자기기에서 가장 많이 사용되고 있는 부품중의 하나인 탄소 피막 가변 저항기에서 접동자 이동시 발생하는 접촉 저항 변화의 원인을 분석하여 이에 대한 감소, 즉 접동 잡음 감소를 위한 몇 가지 방법을 착안하여 실험 검토하고 그 결과을 정리하여 본 결과 균일한 크기를 가진 탄소 분말 입자로서 고루게 배합된 저항액을 사용하고 접동자의 접촉점과 압력을 증가하면 접촉 저항 및 접촉 저항 변화. 즉 잠동 잡음을 감소시킬 수 있다.

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