• 제목/요약/키워드: residue distribution

검색결과 122건 처리시간 0.025초

Anti-hyperlipidemia and Anti-arteriosclerosis Effects of Laminaria japonica in Sprague-Dawley Rats

  • Lee, Seung-Joo;Kim, Chong-Wook;Jang, Hyuk-Jai;Cho, Soon-Yeong;Choi, Jong-Won
    • Fisheries and Aquatic Sciences
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    • 제14권4호
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    • pp.235-241
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    • 2011
  • The anti-hyperlipidemic effects of dietary supplementation with sea tangle Laminaria japonica were investigated using an animal model in which normal rats were fed either sea tangle, sea tangle ethanol extract (EE-ST) and sea tangle extracted residue (ER-ST). Total lipid and triglyceride levels in the serum were significantly (P < 0.05) reduced in rats fed ER-ST at a dose of 200 mg/kg body weight when compared to hyperlipidemic control rats. Significant decreases in serum total cholesterol and low density lipoprotein-cholesterol levels also occurred in rats fed ER-ST at 200 mg/kg body weight. In addition, the atherosclerosis index and superoxide dismutase in blood lipids were significantly (P < 0.05) lowered in rats fed ER-ST at 200 mg/kg body weight as compared to control rats. In conclusion, sea tangle and ER-ST exhibited beneficial anti-hyperlipidemic and anti-arteriosclerosis effects.

Methidathion 중독사에 의한 사후혈액 및 조직중 분포 (Postmortem Distribution of Methidathion in Human Specimens of a Acute Poisoning)

  • 이종숙;이재신;최동기;양희진;이상기;구기서;유영찬
    • 약학회지
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    • 제46권2호
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    • pp.93-97
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    • 2002
  • Methidathion is one of the organophosphorus pesticides commonly used for stamping out harmful pests in farming areas. This paper presents a fatality due to methidathion intoxication and describes the distribution of methidathion in postmortem blood and tissues obtained at autopsy. Qualitative identification of methidathion was achieved by TLC, GC and GC/MS, and quantitative analysis was performed by GC with thermionic specific detector (TSD). The analytes in postmortem specimens were extracted by liquid-liquid extraction (LLE) with ethylether. After the ethylether layer was evaporated, the residue was partitioned into hexane and acetonitrile, and the acetonitrile layer was used for analysis. Tissue specimens were homogenized with 4% perchloric acid and applied for LLE. After extraction, the extracts were reconstituted 100 $\mu\textrm{g}$ pyraclofos (IS, 100 $\mu\textrm{g}$/ml in methanol) for GC and GC/MS analysis. On analysis of postmortem specimens, methidathion was identified and quantitated. The methidathion concentrations were 2.0 $\mu$l/ml in blood, 24.4 $\mu\textrm{g}$/g in liver, 13.9 $\mu\textrm{g}$/g in lung, 21.8 $\mu\textrm{g}$/g in kidney, respectively.

활성탄 입자 조건에 따른 정화통의 압력손실 특성에 관한 연구 (Pressure Loss in Canisters with Conditions of Activated Carbon Particles)

  • 김민욱;김영수;박용환
    • 한국화재소방학회논문지
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    • 제31권4호
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    • pp.7-11
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    • 2017
  • 각종 화재, 폭발, 누출, 테러 사고 시 발생되는 유해가스로부터 작업자나 소방대원들의 안전을 확보하고 원활한 구조활동을 위하여 입자형 활성탄을 여과재로 사용하는 특수 방독면의 필요성이 크게 증가하고 있다. 본 연구에서는 CFD 유동해석을 통하여 활성탄 정화통에 대한 압력손실 특성을 규명하였으며, 해석 결과 호흡유량에 대한 압력손실은 유속이 빠를수록, 여과재의 입자가 작을수록, 공극률이 작을수록 커지지만, 특정 조건 이상에서는 그 변화가 매우 크게 나타나 활성탄 여과재의 선택 시 이를 충분히 고려하여야 하는 것으로 분석되었다.

C 중유의 황 함유량에 따른 CO2 배출 특성 (CO2 Emission Characteristics of Bunker C Fuel Oil by Sulfur Contents)

  • 임완규;도진우;황인하;하종한;이상섭
    • 한국대기환경학회지
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    • 제31권4호
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    • pp.368-377
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    • 2015
  • Bunker C fuel oil is a high-viscosity oil obtained from petroleum distillation as a residue. The sulfur content of bunker C fuel oil is limited to 4.0% or even lower to protect the environment. Because bunker C fuel oil is burned in a furnace or boiler for the generation of heat or used in an engine for the generation of power, carbon dioxide is emitted as a result of combustion. The objective of this study is to investigate $CO_2$ emission characteristics of bunker C fuel oil by sulfur contents. Calorific values and carbon contents of the fuels were measured using the oxygen bomb calorimeter method and the CHN elemental analysis method, respectively. Sulfur and hydrogen contents, which were used to calculate the net calorific value, were also measured and then net calorific values and $CO_2$ emission factors were determined. The results showed that hydrogen content increases and carbon content decreases by reducing sulfur contents for bunker C fuel oil with sulfur contents less than 1.0%. For sulfur contents between 1.0% and 4.0%, carbon content increases as sulfur content decreases but there is no evident variation in hydrogen content. Net calorific value increases by reducing sulfur contents. $CO_2$ emission factor, which is calculated by dividing carbon content by net calorific value, decreases as sulfur content decreases for bunker C fuel oil with sulfur contents less than 1.0% but it showed relatively constant values for sulfur contents between 1.0% and 4.0%.

하동화력발전소 비산재의 입도크기와 미연탄소 함량이 지오폴리머의 압축강도에 미치는 영향 (Effect of Particle Size and Unburned Carbon Content of Fly Ash from Hadong Power Plant on Compressive Strength of Geopolymers)

  • 강남희;전철민;주형태;이수정
    • 한국재료학회지
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    • 제23권9호
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    • pp.510-516
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    • 2013
  • Fly ash is one of the aluminosilicate sources used for the synthesis of geopolymers. The particle size distribution of fly ash and the content of unburned carbon residue are known to affect the compressive strength of geopolymers. In this study, the effects of particle size and unburned carbon content of fly ash on the compressive strength of geopolymers have been studied over a compositional range in geopolymer gels. Unburned carbon was effectively separated in the $-46{\mu}m$ fraction using an air classifier and the fixed carbon content declined from 3.04 wt% to 0.06 wt%. The mean particle size ($d_{50}$) decreased from $22.17{\mu}m$ to $10.79{\mu}m$. Size separation of fly ash by air classification resulted in reduced particle size and carbon residue content with a collateral increase in reactivity with alkali activators. Geopolymers produced from carbon-free ash, which was separated by air classification, developed up to 50 % higher compressive strength compared to geopolymers synthesized from raw ash. It was presumed that porous carbon particles hinder geopolymerization by trapping vitreous spheres in the pores of carbon particles and allowing them to remain intact in spite of alkaline attack. The microstructure of the geopolymers did not vary considerably with compressive strength, but the highest connectivity of the geopolymer gel network was achieved when the Si/Al ratio of the geopolymer gel was 5.0.

Substitution of Pro206 and Ser86 Residues in the Retinal Binding Pocket of Anabaena Sensory Rhodopsin is Not Sufficient for Proton Pumping Function

  • Choi, Ah-Reum;Kim, So-Young;Yoon, Sa-Ryong;Bae, Ki-Ho;Jung, Kwang-Hwang
    • Journal of Microbiology and Biotechnology
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    • 제17권1호
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    • pp.138-145
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    • 2007
  • Anabaena sensory rhodopsin is a seven transmembrane protein that uses all-trans/13-cis retinal as a chromophore. About 22 residues in the retinal-binding pocket of microbial rhodopsins are conserved and important to control the quality of absorbing light and the function of ion transport or sensory transduction. The absorption maximum is 550 nm in the presence of all-trans retinal at dark. Here, we mutated Pro206 to Glu or Asp, of which the residue is conserved as Asp among all other microbial rhodopsins, and the absorption maximum and pKa of the proton acceptor group were measured by absorption spectroscopy at various pHs. Anabaena rhodopsin was expressed best in Escherichia coli in the absence of extra leader sequence when exogenous all-trans retinal was added. The wild-type Anabaena rhodopsin showed small absorption maximum changes between pH4 and 11. In addition, Pro206Asp showed 46 nm blue-shift at pH7.0. Pro206Glu or Asp may change the contribution to the electron distribution of the retinal that is involved in the major role of color tuning for this pigment. The critical residue Ser86 (Asp 96 position in bacteriorhodopsin: proton donor) for the pumping activity was replaced with Asp, but it did not change the proton pumping activity of Anabaena rhodopsin.

광양만 해수 중 유기인 잔류 농약성분의 GC-MS 분석 (GC-MS Analysis of Organophosphorus Pesticide Residue in Seawater From the Kwangyang Bay, Korea)

  • 박미옥;박점숙
    • 한국환경과학회지
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    • 제15권4호
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    • pp.293-304
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    • 2006
  • Sea water samples collected in August, 1994 from 20 stations in the Kwangyang Bay were analyzed by gas chromatography/mass spectrometry-selected ion monitoring (GC/MS-SIM) to investigate persistence and distribution pattern of four organophosphorus pesticides (DDVP, Diazinon, IBP, EDDP). Except for IBP, the contamination by DDVP, Diazinon, and EDDP in marine aquatic environment in Korea has not been reported previously. In this study, however, all these four pesticides were detected in all stations (except DDVP) and their concentrations were in ng/L level. The concentrations ranged from detection limit to 15.3ng/L for DDVP, 1.8-27.7ng/L for Diazinon, 7.3-63.5ng/L for IBP, and 22.2-1100.1ng/L for EDDP. It is noteworthy that the measured concentrations of IBP and EDDP in this study would be much lower than usual, since the use of IBP and EDDP was less than 50% of average annual consumption due to unusually dry and hot weather condition in the summer of 1994. It was very surprising to find that the highest concentrations of organophosphorus pesticides were observed at stations near Daesa Streamlet instead of Seomjin River, which has more point source of the pesticides. This result suggests that the small river discharge during heavy ram period in summer can give harmful effect on marine biota (both wild and aqua-cultured) with its organophosphorus pesticide residue, despite of their short residence time in aquatic environment. In order to protect the marine life properly from acute toxicity of the organophosphorus pesticides, it needs to be emphasized that monitoring the level of agricultural pesticides in river run-off should be done during active consumption period rather at regular intervals.

전북지방에서 사육중인 양식뱀장어의 fluoroquinolones 잔류조사 (Survey of fluoroquinolones residues in cultured eels from the Jeonbuk province)

  • 최민순;황정욱;남현주;최상훈;윤종만;박경일;박성우;박관하
    • 한국어병학회지
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    • 제21권3호
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    • pp.229-239
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    • 2008
  • The aim of this study was to acquire level on the occurrence of five fluoroquinolones(FQs) residue among cultured eels in Jeonbuk province. Samples were collected from the four local area(Kunsan, Gochang, Wanju and Osu) and surveyed on the distribution of FQs residual level in edible muscle using HPLC method. A total of 90 samples of eel was monitored for detection of the FQs residue. Among them, 30 eels(33.3%) were detected the FQs single or paired, respectively. The detection ratios were showed Osu(40%, 8/20), Gochang(33%, 13/44), Wanju(30%, 6/20) and Kunsan(30%, 3/10) in order, respectively. The ratio was equivalent to over 30% of overall in sampled area. The most frequently detected FQs were perfloxacin(PF) followed by enrofloxacin(EF), ciprofloxacin(CF), ofloxacin(OF) and norfloxacin(NF). Eight different combinations of FQ residual patterns were observed as single(5 type, 21%) or as paired(3type, 12,5%) respectively and frequently encountered patterns were PF(37%) and PF-EF(23%). The residual level of FQs was evaluated in the range of 1-75 ug/kg and the most prevalent levels of FQs was found in 1-25 ug/kg(35 fish, 85%) followed by 26-50 ug/kg(5 fishes, 11%) and 51-75 ug/kg(1 fishes, 3.3%). These results could be possible that the cultured eels were mostly exposed with PF, EF and CF, and might be treated with a variety of fluoroquinolones for prevention of bacterial disease.

Characterization and distribution of phenolics in carrot cell walls

  • Kang, Yoon-Han
    • 한국식품저장유통학회:학술대회논문집
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    • 한국식품저장유통학회 2003년도 제23차 추계총회 및 국제학술심포지움
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    • pp.134.1-134
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    • 2003
  • The purpose of this study was to investigate the release of p-hydroxybenzoic acid and other compounds from cell wall materials(CWM) and their cellulose fraction from carrot with chemical and enzymatic hydrolysis. To investigate this effect on cell wall chemistry of carrot, alcohol insoluble residue(AIR) of CWM were prepared and were extracted sequentially with water, imidazole, CDTA(-1, -2), Na$_2$CO$_3$(-1, -2), KOH(0.5, 1.0 and 4M), to leave a residue. These were analysed for their carbohydrate and phenolic acids composition. Arabinose and galactose were the main noncellulosic sugars. Phenolics esterified to cell walls in carrot were found to consist primarily of p-hydroxybenzoic acid with minor contribution from vanillin, ferulic acid and p-hydroxybenzaldehyde. p-Hydroxybenzoic acid was quite strongly bound to the cell wall. The contents of p-hydroxybenzoic acid in 0.5M KOH, Na$_2$CO$_3$-2, IM KOH, and ${\alpha}$-cellulose were 2,097, 1,360, 1,140, and 717 $\mu\textrm{g}$/g AIR from CWM, respectively. Alkali labile unknown aromatic compound(C$\sub$7/H$\sub$10/O$_2$) was found in ${\alpha}$ -cellulose hydrolyzate digested with driselase and cellulase. This compound was also found in hydrolyzate of 2 M trifluoroacetic acid at 120$^{\circ}C$ for 2 hours. Driselase treatment solubilized only 46.6 $\mu\textrm{g}$/g of the p-hydroxybenzoic acid from carrot AIR. These results indicate that p-hydroxybenzoic acid was associated with neutral polysaccharides, long chain galactose and branched arabinan from graded alcohol precipitation.

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CRD를 이용한 전자파 잔향실 내 전기장 균일도 향상 (Improved Field Uniformity Characteristics in a Reverberation Chamber with a CRD)

  • 손용호;이중근;김정훈
    • 대한전자공학회논문지TC
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    • 제44권12호
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    • pp.79-84
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    • 2007
  • 본 논문에서는 CRD(Cubical Residue Diffuser)를 이용하여 전자파 잔향실 내의 전기장 균일도를 향상시키고, 잔향실 내의 전기장 균일도가 최적화되는 CRD 면적비를 연구하였다. $1\sim3$ GHz 주파수 대역에서 Schroeder 방식의 CRD를 설계하였고, 전자파 잔향실 내의 전기장 분포 해석을 위해 FDTD(Finite Difference Time Domain) 수치해석이 이루어졌다. 해석결과 2 GHz에서 CRD의 면적이 잔향실 한쪽 내벽의 약 $40\sim80%$일 경우 전기장 강도 표준 편차가 낮고 균일하게 분포되었으며, 40 % 이하, 또는 80 % 이상의 면적에서는 표준 편차가 높게 나타났다. 특히 가장 나쁜 경우와 비교하여 44%일 때 전기장 균일도가 1 dB 향상됨을 알 수 있었다.