• Journal of Veterinary Clinics
• /
• v.24 no.1
• /
• pp.5-9
• /
• 2007

The purpose of this study was to examine the allometric analysis of roxithromycin using pharmacokinetic data. The pharmacokinetic parameters used were $half-life(t_{1/2})$, mean residence time (MRT), clearance (Cl) and volume of distribution at steady state $(V_{ss})$. Relationships between body weight and the pharmacokinetic parameter were based on the empirical formula $Y=aW^b$, where 'Y' is $t_{1/2}$, MRT, Cl, or $V_{ss}$, W the body weight and 'a' is an allometric coefficient (intercept) that is constant for a given drug. The exponential term, 'b', is a proportionality constant that describes the relationship between the pharmacokinetic parameter of interest and body weight. As results of the allometric analyses, the logarithms of $t_{1/2}$, MRT, Cl, and $V_{ss}$ were linearly related to the logarithms of body weight. Results of the current analyses could provide information on appropriate doses of roxithromycin for all species.

• Korean Journal of Microbiology
• /
• v.38 no.2
• /
• pp.119-126
• /
• 2002

ATP concentrations far estimating total microbial biomass in the sediment were measured in three different marine sedimentary environments. ATP concentrations were highest in the surface sediment and decreased with increasing sediment depth and distance from the land. The results indicated that the benthic microbial biomass is primarily controlled by nutrient inputs from the overlying water column. Because of the longer residence time and adsorption to the sediment, the variations in organic carbon (OC) contents with sites and depths were not as distinct as that of ATP, and the correlation between OC and ATP was not significant in the coastal sediments. No significant correlation between OC and ATP in the coastal sediments also suggested that microbial biomass in the labile organic-enriched coastal sediment is suppressed by the grazing of higher trophic level such as meiofauna. Overall regional and vertical distribution of ATP indicated that h\`w can be a relevant tool for measuring total microbial biomass in various marine sedimentary environments.

• Journal of Korean Society of Environmental Engineers
• /
• v.37 no.5
• /
• pp.285-292
• /
• 2015

In this study, we were clearly identify the behaviour characteristics on particle size distribution of a condensing species by injection condition of HMDS (Hexa Methyl Di-Silazane, silica precursor that is one of liquid adsorbents) to remove condensing gaseous species as using pyroligneous liquor generated during carbonization process of biomass as precursor of condensing gaseous species. When using HMDS to remove the condensing gaseous species by growth machanism of particles, we could be controlled properly particles size such as amount of adsorbent injection, residence time, heating temperature and MFC flux. Especially, in case of using the silica precursor, in consideration of the physical and chemical properties of the boiling point, the specific gravity and the molecular weight, we found that the condensing species could be effectively controlled by particles granulation.

• Journal of the Korean Society of Combustion
• /
• v.19 no.3
• /
• pp.1-7
• /
• 2014

Experimental study has been carried out to understand combustion characteristics of a swirl-stabilized premixed gas turbine combustor for power generation. $NO_x$ and CO emissions, extinction limit, pressure loss, and temperature distribution were measured for various operating conditions. Results show that, with increasing inlet air temperature, $NO_x$ is increased due to a higher adiabatic flame temperature while CO is increased or decreased for low or high A/F ratio regime, respectively. depending on the flame location. With decreasing load from the design condition, $NO_x$ is decreased as thermal load is reduced. With further decreasing load, however, $NO_x$ is increased due to a longer residence time. CO is decreased and then increased with decreasing load. Flame extinction limit is extended with increasing inlet air temperature as the recirculation strength is enhanced.

• Journal of Korean Society on Water Environment
• /
• v.22 no.3
• /
• pp.546-556
• /
• 2006

The purpose of this study is to improve the polluted stream water quality by pilot-scale five different constructed wetlands (CWs). Cell 1 to 3 are newly designed 2SFCW (Surface-subsurface flow CW) with 1 to 3 flow shifters (FS) in the middle of the wetland system. Cell 4 and 5 are control CW (CCW), but Cell 5 is the same type as Cell 3. The FS, which converts the route of surface and subsurface flow between two wetlands connected in series, was able to enhance the treatability of TN via nitrification and denitrification and of SS due to filtration and sedimentation. The void fraction and dispersion number of Cell 1, 2 and 3 obtained from the RTD analysis were found to be 0.73 and 0.17, respectively. COD and TP removal efficiencies of Cell 1 to 3 were similar to that of Cell 4 and 5. SS removal efficiencies of Cell 1 to 3 and 5 with FS were 5-10% higher than that of Cell 4 without FS. TN removal efficiencies of Cell 1 to 3 were 3-14% higher than that of Cell 4 and 5. The average $R^2$ values of COD, SS, TN and TP obtained from nonlinear regression analysis were similar to the results of other researchers.

• Journal of Soil and Groundwater Environment
• /
• v.26 no.5
• /
• pp.39-48
• /
• 2021

Analysis of the change in water content and distribution was conducted according to the supply of recirculation water to a landfill. An excavation sample analysis showed that the recirculation water injection zone had water content 8.8% point higher than that of the non-injection zone, after 8 months of operation. And due to the influence of recirculation water supply by vertical wells in injection zones, the water content increases along with depth more clearly than non-injection zone. According to an electrical specific-resistivity survey after 13 months of operation, the water content got higher towards the bottom of the landfill. The water transmission coefficient is 8.72×10^-4 cm/sec for injection zones and 3.36×10^-5 cm/sec for the intermediate cover layer; analysis shows that the intermediate cover layer may affect the penetration velocity of water supplied by the horizontal injection tube. For the scientific design and operation of re-injection facilities, it was deemed necessary to follow-up research on the residence time and behavior of re-injection water considering the ratio of recirculation water supply in horizontal and vertical tubes, and pitcher coefficient of intermediate and waste layers.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2023.05a
• /
• pp.518-518
• /
• 2023

자연하천에서 오염물질의 혼합 거동은 비균일한 지형학적 요인으로 인해 매우 복잡한 특성을 나타낸다. 일반적으로 오염물질 거동 모델링에서는 수체에서의 혼합을 Fick의 법칙에 따라 유속에 의한 이송과 난류에 의한 확산으로 계산하고, 국부적인 정체현상 등에 의한 non-Fickian 혼합을 야기하는 하천의 특성을 기하학적 지형 형상으로 구현하여 실제 현상에 근접한 혼합 거동을 재현한다. 하지만 계산의 효율성을 위하여 모델링의 차원을 낮추는 경우, 하천의 지형을 경계조건으로 고려할 수 없게 된다. 특히, 1차원 모델링의 경우 하천의 비균일성을 무시하고 1개의 유선으로 간주하며, 이 경우 non-Fickian 물질이동 해석을 위한 추가적인 현상학적 해석이 필요하다. 지난 50년간, non-Fickian 물질이동 해석을 위한 다양한 현상학적 모형이 제시되어 왔다. 하천을 흐름영역과 정체영역으로 구분하고 두 개의 영역 사이의 물질교환 속도를 모델링하거나, Random walk 개념으로 물질이 이동하는 경우와 이동하지 않는 경우를 확률론적으로 모델링하거나, 물질이 정체되었을 때 다시 빠져나오는 시간을 모델링하는 경우가 그 예이다. 본 연구에서는 선행연구에서 제시한 음함수 형태의 현상학적 모형을 기반으로, 수치적 반복계산 없이 상류 경계에서 임의의 형태의 농도곡선(shape-free breakthrough curve)을 갖는 오염물질운(cloud)이 일정 거리를 유하하며 발생하는 변화를 예측할 수 있는 해를 제시한다. 본 연구의 방법론은 추적법(routing procedure)을 활용한 Fickian 혼합 해석, 전달함수(transfer function) 형태의 정체시간분포 해석, 그리고 라플라스 도메인에서의 해석해 유도를 포함한다. 본 연구에서 제시된 해는 2020년 경상북도 김천시에 위치한 감천의 4.5 km 구간에서 수행한 추적자 실험의 현장 자료를 통해 정확도를 검증하여 타당성을 입증하였다.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2021.06a
• /
• pp.200-200
• /
• 2021

하천은 용수공급, 관개, 친수활동, 산업활동 등 인간의 활동에 중요한 역할을 한다. 이에 따라 수질관리는 필수적이며 유기물, 중금속, 화학물질 등의 용존물질들은 수질문제에 직접적으로 영향을 미친다. 따라서 하천에서의 용존물질의 혼합 거동을 파악하기 위한 연구가 지난 수십년간 이루어지고 있다. 하천 흐름에 따른 오염물질의 이동 및 확산 거동을 예측하기 위하여 1차원 추적모형이 활용되는데, 그 중 하천저장대 모형(Transient Storage Model, TSM)은 자연하천의 복잡하고 불규칙한 수리·지형적인 특성을 단순하게 반영할 수 있다는 장점때문에 가장 많이 사용된다. 하지만 TSM은 매개변수에 대한 의존성과 불확도가 크며, TSM의 저장대에서의 농도분포에 대한 지수함수형태의 모델링이 하상간극수역(Hyporheic zone)에서의 저장대 특성을 반영하기에 구조적으로 부정확하다는 단점이 제기되고 있다. 최근 이러한 TSM의 단점을 보완하고 하천에서의 저장대 메커니즘을 보다 정확하게 구현하고자 체류시간분포(residence time distribution)를 이용한 확률론적 저장대 모델링 프레임워크가 등장하고 있다. 본 연구에서는 본류대와 저장대에서의 오염물질의 체류시간분포를 분리하여 해석하고 이를 전달함수(transfer function)를 이용한 합성곱으로 결합한 형태의 프레임워크를 적용하여 모델링하였다. 상기의 모형을 검증하기 위하여 2019년 감천의 4.85km 구간에서 추적자 실험을 실시하였다. 실험 당시 유량은 12.9 m³/s로 풍수기에 해당되며 평균 유속은 약 0.6 m/s로 측정되었다. 모형의 매개변수는 추적자 실험으로부터 최적화 기법을 통해 역모델링기법으로 결정하였다. 제안된 모형에 의한 모의 결과를 추적자 실험에서의 농도측정자료와 비교한 결과, 평균 0.988의 결정계수를 보여 매우 높은 정확도를 보이고 있음을 알 수 있었다. 저장대특성을 나타내는 농도곡선의 꼬리부에 대하여 같은 조건에서 1차원 이송-분산(ADE) 모형, TSM의 모의결과와도 비교한 결과 본 모형은 추적자 실험 농도측정 결과와 평균 0.195의 오차율을 보이며, 이는 ADE 모형과 TSM의 오차율인 14.03과 1.866에 비해 매우 정확한 것으로 나타났다.

• Journal of environmental and Sanitary engineering
• /
• v.24 no.4
• /
• pp.1-26
• /
• 2009

We conclude the following with air pollution data measured from city measurement net administered and managed in Gwangju for the last 7 years from January in 2001 to December in 2007. In addition, some major statistics governed by Gwangju city and data administered by Gwangju as national official statistics obtained by estimating the amount of national air pollutant emission from National Institute of Environmental Research were used. The results are as follows ; 1. The distribution by main managements of air emission factory is the following ; Gwangju City Hall(67.8%) > Gwangsan District Office(13.6%) > Buk District Office(9.8%) > Seo District Office(5.5%) > Nam District Office(3.0%) > Dong District Office(0.3%) and the distribution by districts of air emission factory ; Buk District(32.8%) > Gwangsan District(22.4%) > Seo District(21.8%) > Nam District(14.9%) > Dong District(8.1%). That by types(Year 2004~2007 average) is also following ; Type 5(45.2%) > Type 4(40.7%) > Type 3(8.6%) > Type 2(3.2%) > Type 1(2.2%) and the most of them are small size of factory, Type 4 and 5. 2. The distribution by districts of the number of car registrations is the following ; Buk District(32.8%) > Gwangsan District(22.4%) > Seo District(21.8%) > Nam District(14.9%) > Dong District(8.1%) and the distribution by use of car fuel in 2001 ; Gasoline(56.3%) > Diesel(30.3%) > LPG(13.4%) > etc.(0.2%). In 2007, there was no ranking change ; Gasoline(47.8%) > Diesel(35.6%) > LPG(16.2%) >etc.(0.4%). The number of gasoline cars increased slightly, but that of diesel and LPG cars increased remarkably. 3. The distribution by items of the amount of air pollutant emission in Gwangju is the following; CO(36.7%) > NOx(32.7%) > VOC(26.7%) > SOx(2.3%) > PM-10(1.5%). The amount of CO and NOx, which are generally generated from cars, is very large percentage among them. 4. The distribution by mean of air pollutant emission(SOx, NOx, CO, VOC, PM-10) of each county for 5 years(2001~2005) is the following ; Buk District(31.0%) > Gwangsan District(28.2%) > Seo District(20.4%) > Nam District(12.5%) > Dong District(7.9%). The amount of air pollutant emission in Buk District, which has the most population, car registrations, and air pollutant emission businesses, was the highest. On the other hand, that of air pollutant emission in Dong District, which has the least population, car registrations, and air pollutant emission businesses, was the least. 5. The average rates of SOx for 5 years(2001~2005) in Gwangju is the following ; Non industrial combustion(59.5%) > Combustion in manufacturing industry(20.4%) > Road transportation(11.4%) > Non-road transportation(3.8%) > Waste disposal(3.7%) > Production process(1.1%). And the distribution of average amount of SOx emission of each county is shown as Gwangsan District(33.3%) > Buk District(28.0%) > Seo District(19.3%) > Nam District(10.2%) > Dong District(9.1%). 6. The distribution of the amount of NOx emission in Gwangju is shown as Road transportation(59.1%) > Non-road transportation(18.9%) > Non industrial combustion(13.3%) > Combustion in manufacturing industry(6.9%) > Waste disposal(1.6%) > Production process(0.1%). And the distribution of the amount of NOx emission from each county is the following ; Buk District(30.7%) > Gwangsan District(28.8%) > Seo District(20.5%) > Nam District(12.2%) > Dong District(7.8%). 7. The distribution of the amount of carbon monoxide emission in Gwangju is shown as Road transportation(82.0%) > Non industrial combustion(10.6%) > Non-road transportation(5.4%) > Combustion in manufacturing industry(1.7%) > Waste disposal(0.3%). And the distribution of the amount of carbon monoxide emission from each county is the following ; Buk District(33.0%) > Seo District(22.3%) > Gwangsan District(21.3%) > Nam District(14.3%) > Dong District(9.1%). 8. The distribution of the amount of Volatile Organic Compound emission in Gwangju is shown as Solvent utilization(69.5%) > Road transportation(19.8%) > Energy storage & transport(4.4%) > Non-road transportation(2.8%) > Waste disposal(2.4%) > Non industrial combustion(0.5%) > Production process(0.4%) > Combustion in manufacturing industry(0.3%). And the distribution of the amount of Volatile Organic Compound emission from each county is the following ; Gwangsan District(36.8%) > Buk District(28.7%) > Seo District(17.8%) > Nam District(10.4%) > Dong District(6.3%). 9. The distribution of the amount of minute dust emission in Gwangju is shown as Road transportation(76.7%) > Non-road transportation(16.3%) > Non industrial combustion(6.1%) > Combustion in manufacturing industry(0.7%) > Waste disposal(0.2%) > Production process(0.1%). And the distribution of the amount of minute dust emission from each county is the following ; Buk District(32.8%) > Gwangsan District(26.0%) > Seo District(19.5%) > Nam District(13.2%) > Dong District(8.5%). 10. According to the major source of emission of each items, that of oxides of sulfur is Non industrial combustion, heating of residence, business and agriculture and stockbreeding. And that of NOx, carbon monoxide, minute dust is Road transportation, emission of cars and two-wheeled vehicles. Also, that of VOC is Solvent utilization emission facilities due to Solvent utilization. 11. The concentration of sulfurous acid gas has been 0.004ppm since 2001 and there has not been no concentration change year by year. It is considered that the use of sulfurous acid gas is now reaching to the stabilization stage. This is found by the facts that the use of fuel is steadily changing from solid or liquid fuel to low sulfur liquid fuel containing very little amount of sulfur element or gas, so that nearly no change in concentration has been shown regularly. 12. Concerning changes of the concentration of throughout time, the concentration of NO has been shown relatively higher than that of $NO_2$ between 6AM~1PM and the concentration of $NO_2$ higher during the other time. The concentration of NOx(NO, $NO_2$) has been relatively high during weekday evenings. This result shows that there is correlation between the concentration of NOx and car traffics as we can see the Road transportation which accounts for 59.1% among the amount of NOx emission. 13. 49.1~61.2% of PM-10 shows PM-2.5 concerning the relationship between PM-10 and PM-2.5 and PM-2.5 among dust accounts for 45.4%~44.5% of PM-10 during March and April which is the lowest rates. This proves that particles of yellow sand that are bigger than the size $2.5\;{\mu}m$ are sent more than those that are smaller from China. This result shows that particles smaller than $2.5\;{\mu}m$ among dust exist much during July~August and December~January and 76.7% of minute dust is proved to be road transportation in Gwangju.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.29 no.2
• /
• pp.238-245
• /
• 1996

Vertical profiles of $^{210}Po\;and\;^{210}Pb$ were measured for the upper 100 m of water column at six stations in the middle region of the Korean East Sea during March 1993. The distribution patterns of these radionuclides with the water mass and controlling factors on their distributions were also discussed. $^{210}Pb$ activities were generally high at surface water and gradually decrease with depth. Vertical profiles of $^{210}Po$ were relatively homogeneous except for at station E3, where chlorophyll-a concentration was the highest and $^{210}Po$ activity in the upper 30 m was lower than below 50 m. The $^{210}Po$ activities relative to its parent $^{210}Pb$ at all stations were deficient at the upper 30 m, but were excess or nearly equilibrated values below 50 m. The magnitude of $^{210}Po$ deficiency was relatively high at station E3 and E6, where strong thermocline occured. However, $^{210}Pb$ activities showed strong excess in the upper 100 m of all stations, compared with its parent $^{226}Ra$. The residence time of $^{210}Po$ ranged from 1.0 to 7.8 years, and was relatively short at station E3 and E6. The data obtained at the upper 50 m water column during $1992\~1994$, also showed that removal rate constant of $^{210}Po$ and inventories of chlorophyll-a was negatively related. This indicates that the primary production plays an important role in controlling the distributions of $^{210}Po$ at the upper water column of the Korean last Sea in spring. While, inventories of excess $^{210}Pb$ was generally decreasing with increasing density difference between 50 m and 100 m, suggesting that $^{210}Pb$ concentrations in the upper water column were controlled by stability of water column.