• 제목/요약/키워드: research university

검색결과 198,831건 처리시간 0.144초

Discriminatian of Cnidium Rhizame using PCR-mediated RFLP

  • Cho, So-Yean;Ze, Keum-Ryon;Seong, Rack-Seon;Lee, Jong-Pill;Ju, Young-Park;Park, Sang-Yong;Jung, Young-Ja;Cho, Chang-Hee;Ha, Kwang-Won;Suh, Young-Bae
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.367.2-367.2
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    • 2002
  • Cnidium Rhizome is a frequently prescribed herbal medicine in Korea, Japan as well as China, which has been successfully used in these countries for the treatment of diseases related to. gynecology, blood circulations and dental troublers in the name of 천궁. And it is circulated as the same chinese character, which is 천궁, although original plants are different as Cnidium officinale in pharmacopoeia of Korea or Japan and Ligusticum chuanxiong Hort. In that of China. (omitted)

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Synthesis of N,N',N"-Trisubstituted Thiourea Derivatives and their Antagonistic Effect on the Vanilloid Receptor

  • Park, Hyeung-Geun;Park, Mi-Kyung;Choi, Ji-Yeon;Choi, Sea-Hoon;Lee, Ji-Hye;Suh, Young-Ger;Cho, Ha-Won;Oh, Uh-Taek;Lee, Jee-Woo
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.253.1-253.1
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    • 2003
  • Twenty-seven N,N',N"-trisubstituted thiourea derivatives were prepared. Among them, 1- [3-(4'-hydroxy-3'-methoxy-phenyl)-propyl] -1,3-diphenethyl-thiourea (81, IC$\sub$50/= 0,32 $\mu\textrm{m}$), showed 2-fold higher antagonistic activity than that of capsazepine (3, IC$\sub$50/= 0,65 $\mu\textrm{m}$) against the vanilloid receptor in a Ca$\^$2+/ -influx assay.

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The Study on the drug pharmacokinetics according to the progression of liver disease

  • Sohn, Soo-Jung;Choi, Hong-Serck;Ahn, Mee-Ryung;Chung, Hye-Joo;Yoo, Tae-Moo;Lee, Min-Ho;Park, Moon-Seung;Shin, In-Chul;Kim, Ju-ll
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.308.1-308.1
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    • 2003
  • We underwent this study to know correlation between the amount of portosysternic shunt/hepatic fibrosis and bioavailability parameters such as AUC, Cmax, Tmax and t1 /2 of high extraction ratio drug, propranolol, in CCl4-induced liver cirrhosis model of rats. This study describes the bioavaility study of propranolol(5 mg/kg), Shunt Index using thallium-201 per rectum scintigraphy to to measure the amount of portosystemic shunt indirectly and intrahepatic hydroxyproline content performed in the CCl4-induced liver cirrhosis model of rats. (omitted)

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