• Proceedings of the PSK Conference
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• 2001.10a
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• pp.259.1-259.1
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• 2001

• Proceedings of the Korean Magnetic Resonance Society Conference
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• 1999.02a
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• pp.19-21
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• 1999

• IMMUNE NETWORK
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• v.22 no.2
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• pp.14.1-14.17
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• 2022

Osteoarthritis (OA) is a common degenerative joint disease characterized by breakdown of joint cartilage. Mitochondrial dysfunction of the chondrocyte is a risk factor for OA progression. We examined the therapeutic potential of mitochondrial transplantation for OA. Mitochondria were injected into the knee joint of monosodium iodoacetate-induced OA rats. Chondrocytes from OA rats or patients with OA were cultured to examine mitochondrial function in cellular pathophysiology. Pain, cartilage destruction, and bone loss were improved in mitochondrial transplanted-OA rats. The transcript levels of IL-1β, TNF-α, matrix metallopeptidase 13, and MCP-1 in cartilage were markedly decreased by mitochondrial transplantation. Mitochondrial function, as indicated by membrane potential and oxygen consumption rate, in chondrocytes from OA rats was improved by mitochondrial transplantation. Likewise, the mitochondrial function of chondrocytes from OA patients was improved by coculture with mitochondria. Furthermore, inflammatory cell death was significantly decreased by coculture with mitochondria. Mitochondrial transplantation ameliorated OA progression, which is caused by mitochondrial dysfunction. These results suggest the therapeutic potential of mitochondrial transplantation for OA.

• Korean Journal of Pharmacognosy
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• v.12 no.3
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• pp.153-170
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• 1981

• Proceedings of the Korean Magnestics Society Conference
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• 2007.05a
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• pp.233.1-233.1
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• 2007

• 대한생식의학회:학술대회논문집
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• 2004.11a
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• pp.95-95
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• 2004

• Bulletin of the Korean Chemical Society
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• v.32 no.4
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• pp.1407-1410
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• 2011

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.236-237
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• 2010

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.282-283
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• 2010

• Korean Journal of Radiology
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• v.2 no.2
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• pp.97-104
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• 2001

Pelvic fistulas may result from obstetric complications, inflammatory bowel disease, pelvic malignancy, pelvic radiation therapy, pelvic surgery, or other traumatic causes, and their symptoms may be distressing. In our experience, various types of pelvic fistulas are identified after pelvic disease or pelvic surgery. Because of its close proximity, the majority of such fistulas occur in the pelvic cavity and include the vesicovaginal, vesicouterine, vesicoenteric, ureterovaginal, ureteroenteric and enterovaginal type. The purpose of this article is to illustrate the spectrum of imaging features of pelvic fistulas.