• Journal of Microbiology and Biotechnology
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• v.7 no.1
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• pp.49-51
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• 1997

In order to obtain a hybrid synthetic peptide with a more potent antifungal activity than magainin-2 but without hemolytic activity, four hybrid peptides were designed from the sequences of magainin 2 and cecropin A and their antifungal activities against Trichosporon beigelii were investigated. The result showed that analogue 2 and 4 exhibited better antifungal activity against T. beigelii than magainin-2 but no hemolytic activities. The peptides, therefore, could be used as models for the development of potent antifungal peptides.

• Journal of Korean Academy of Nursing
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• v.34 no.5
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• pp.838-848
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• 2004

Purpose: This study was to describe nurses' research activities, perceptions and performances of evidence-based practice and barriers to the use of research evidence in nursing practice in Korea. Method: A cross-sectional survey design was used. A questionnaire, except for Barriers Scale, was developed for the study. Data was collected from a convenient sample of 437 registered nurses working at research and education oriented university hospitals. Result: Nurses' research-related activities were relatively low compared to previous studies. Also perceptions and performances of evidence based nursing practice were low. Preferred informational resources for clinical decision making were identified as ward manuals/clinical guidelines, manager/senior nurses, and literature/research. The major barriers to research utilization were a lack of implication for practice along with inadequate facilitation to implement research evidence and difficulty understanding research written in English. Priorities of barriers factor were Administrator, Communication, Adopter, and Research. Conclusion: The findings provide directions for future training, education, and managerial policy to achieve successful evidence based nursing practice.

• Journal of Engineering Education Research
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• v.19 no.1
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• pp.11-20
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• 2016

Team activities in engineering curriculum play the major role in nourishing students with problem-solving and team-working capabilities. Educators endeavor to guide students to achieve success experiences through team activities. The sense of success depends on how the students think and feel about team activities. In this study, we investigated the students thoughts on team activity in various aspects. We provided freshmen and juniors with a set of questionnaire and gathered answers, from which we tried to elicit implication that we may apply for coaching their team activities. The analysis result shows that the perception level of freshmen on team activities is less mature in a sense that the freshmen's view is more neutral than that of juniors. Regardless of the grade, they show that they put more emphasis on the team atmosphere than on the team performance. Especially the freshmen are more sensitive to the relationship between the team members than the juniors. The juniors concern more about whether they prepare well enough for the team activities or not. Both of the grades prefer self-regulation in team formation and think the leadership is essential in performing team activities. However, they both hesitate to take a role as a leader. We expect the research result will provide novel ideas for coaching students to obtain valuable experiences on team activities.

• Journal of Marine Bioscience and Biotechnology
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• v.1 no.3
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• pp.144-155
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• 2006

This report reviews the literatures on chemical constituents of marine sponges of the genus Spongosorites and also highlights our own research. Specific biological activities of the metabolites from these sponges include: cytotoxic, antitumor, antibacterial, antifungal, antiviral, anti-inflammatory, and other pharmacological activities.

• Journal of Ginseng Research
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• v.22 no.1
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• pp.18-21
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• 1998

Comparative cytotoxic activities of petroleum ether soluble fraction from various ginsengs of Panax species were evaluated using A549 (human lung adenocarcinoma) and SK-OV-3(human ovary carcinoma) cancer cell lines. Korean red ginseng, Korean white ginseng, American ginseng and Canadian ginseng were found to show more potent cytotoxicitles on A549 and SK-OV-3 cell lines than Chinese red ginseng, Japanese red ginseng and Sanchi ginseng. It is noteworthy that especially, red ginseng prepared from the root of Panax ginseng cultivated in Korea shows relatively stronger cytotoxic activities than those cultivated in China and Japan.

• Archives of Pharmacal Research
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• v.10 no.2
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• pp.115-120
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• 1987

Methanol extract of Ilex pubescens roots prolonged bleeding time threefold, and inhibited the generation of malondialdehyde released during platelet aggregation inducted by thrombin. Through several purification procedures, its saponin, named ilexoside, was proved to be responsible for the antithrombotic activities of the plant. Ilexosides A, -D and -J and 24-carboxypomolic acid showed strong inhibitory activities on platelet aggregation induced by thrombin.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.1 no.1
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• pp.73-82
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• 2000

Conventional funding system for the university research projects is limited to a grant or subsidy type funding method which does not require an obligation of refund. Such a funding system is known as ideal one for the university research activities which in general is not a profit oriented activities. It is considered ideal in a sense that nonprofit oriented research activities gives more emphasis on creativity than on efficiency or practical value. A venture- business-start-up research activity can not be considered as a pure nonprofit oriented activities. It clearly gives more emphasis on efficiency and practical value than on creativity Recently a large portion of the venture-business-start-up research activities are carried out in the universities. When a conventional research funding system is applied to such a new type of research activities, it turned out that the success rate is much lower than expectancy. This is why a new and differentiated funding system is sought for such a new type of research activities. A funding system of loan type for a venture-business-start-up research activities is proposed herewith. A loan system naturally requires a pay back after the successful start up of the venture business. This loan system nay be considered that a business concept is grafted on a conventional funding system for the university research activities. This means that a rather loose or generous terms and conditions of the money loan case is introduced into this funding system to remedy the short comings of the intrinsic nonprofit nature of the university research activities. The point is how to improve the success rate and how to reduce the undesirable aspect of the conventional university research activities when it is practiced with the new type of research activities. After one and half year of practicing with the new funding system. it can not be asserted that a definitely positive results could be obtained. but a trend of desirable aspects could be observed such as low drop out rate. project selection efficiency, higher sense of responsibility. etc.

• Archives of Pharmacal Research
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• v.27 no.2
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• pp.184-188
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• 2004

The present study was carried out to clarify whether tectorigenin and tectoridin isolated from the rhizomes of Belamcanda chinensis (Iridaceae) inhibit hepatic damage induced by carbon tetrachloride ($CCl_4$)-intoxication in rats by the experimental methods in vitro and in vivo. Tectorigenin and tectoridin exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by $CCl_4$-intoxication in rats, as well as in a lipid peroxidation causing a significant decrease in malondialdehyde (MDA) production by thiobarbituric acid (TBA)-reactant assay. Both compounds also showed strong increase in the antioxidant enzymes such as hepatic cytosolic superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-px) activities in $CCl_4$-intoxicated rats. These results suggested that tectorigenin and tectoridin isolated from the rhizomes of B. chinensis possess not only the antioxidative, but also the hepatoprotective activities in $CCl_4$ -intoxicated rats.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.4
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• pp.9-17
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• 2019

PURPOSE: This research was designed to study the correlations between physical activities such as foot sensory impairment, balance and ambulatory abilities, as well as fall risk factors and mental activities such as cognitive performance and depression in order to provide fundamental data for the prevention of falling in the elderly. METHODS: A total of 36 elderly people over the age of 65 years who voluntarily joined the research were selected as subjects. Sensory perception in both feet was measured by using a monofilament in 10 parts with each part given one point. The points for each foot were integrated to analyze the correlations between physical and mental activities indices, and the results were analyzed by using Pearson's correlation coefficient. RESULTS: The results of this research show that the extent to which senses in feet were impaired was correlated to TUG, a functional activity index involved in tranfers, gait, and turning movements, which was correlated to BBS (balance index) as well as MMSE-K and K-GDS (mental activities index). BBS was interrelated to FES-K (physical activities index) and MMSE-K. The muscular strength of the right ankle dorsiflexor had mutual relations with FES-K. CONCLUSION: The results of this research indicate that TUG is widely correlated to foot sensory impairment as well as general physical and mental activities in elderly people. BBS was also shown to be correlated with TUG, FES-K, and MMSE-K. Thus, it might be necessary that TUG and BBS be included as two items in physical and mental check-ups for the elderly, and further studies on correlations using evaluation items for physical and mental activities should lead to the simplification of the evaluation criteria.

• Journal of People, Plants, and Environment
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• v.23 no.4
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• pp.411-422
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• 2020

Background and objective: This study was conducted to find out the effects of healing farm resources and participant satisfaction on the level of stress and loyalty. Methods: The experiment was conducted on 18 subjects who participated in agro-healing activities (aged 49.5 years on average) and the concentration of cortisol, the level of stress and satisfaction with the services and program of a healing farm. The healing-agriculture activities were performed once a week, a total of 7 sessions, for 90 minutes and their saliva was collected before and after the activities. Results: The concentration of cortisol, a stress hormone, was statistically significantly reduced after the healing-agriculture activities in 5 out of 7 sessions. The total cortisol concentration showed statistically significant differences. The 6th session was comprised of different activities, compared to others, such as understanding weeds, managing a garden and making a pizza with fermentation enzymes, and the level of cortisol in the 6th session was the lowest after participating in the agro-healing activities, which indicated that the activities have the positive effect of lowering the level of stress. The level of stress was lowered from 18.39 to 16.78, which was consistent with the results of the concentration of cortisol. The level of satisfaction in the last session was below 50%, which indicated that the owner of the farm might be a little inexperienced in education and marketing on information and safety. The variables of participants including stress and satisfaction with services showed a strong influence on their loyalty. Conclusion: Satisfaction with services and loyalty to the healing farm showed a very high correlation, which was statistically significant. It also showed that participants' stress level and satisfaction with the services and program of the healing farm have a strong influence on their loyalty.