• Clinical and Experimental Pediatrics
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• v.62 no.4
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• pp.113-118
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• 2019

Inappropriate antibiotic use is the most important factor causing increased bacterial resistance to antibiotics, thus affecting patient outcomes. Multidrug-resistant bacteria have become a serious public health threat, causing significant morbidity and mortality worldwide. In Korea, the burden of antibiotic-resistant bacteria has become an important public health issue. There is increasing evidence of overuse and misuse of antibiotics in Korea, as observed in cohorts with large sample sizes. Antibiotic use among children should receive particular attention because of the frequency of community-associated infections among this population and the elevated risk of transmission. Recent studies from Korea have demonstrated that the use of broad-spectrum antibiotics, either for inpatient or outpatient treatment, has increased among many age groups, especially children. In this review, we aim to describe the patterns of antibiotic prescription and evaluate recent trends in antibiotic use among children. Coordinated efforts toward communication and education in order to address misunderstandings regarding antibiotic use, involving interprofessional antimicrobial stewardship programs, are required in the near future.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.9
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• pp.783-790
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• 2016

Since scarcity of spectrum in future mobile networks, millimeter wave frequencies from 30 GHz to 300 GHz have been proposed to be used in an important part of 5G mobile communication backhaul links to provide several giga bits services. In ITU-R has been invited to conduct and complete in time for WRC-19 the appropriate studies to determine the spectrum needs for the terrestrial component of IMT in the frequency range between 24.25 GHz and 86 GHz. Also, small cells such as a femtocell, and heterogeneous networks have been deployed through world in order to enhance the communication capacity. At this stage, it is important to develop millimeter wave frequencies to provide 5G mobile broadband services, and thus this paper proposes the effective usage of these frequencies by summarizing the FCC allocation of millimeter waves, their propagation characteristics, the required minimum path length, and the interference effect.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.166-172
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• 2016

This paper deals with the seismic qualification of the reflective metal insulation for thermal shielding that is installed on the outer surfaces of the main equipment of the primary coolant system of a nuclear power plant. A small-scale model of the reactor pressure vessel, which has equivalent dynamic characteristics, was designed to be tested in domestic seismic testing facilities in the future. In this study, seismic analysis of the small-scale model installed with metal insulation was performed using equivalent static analysis and response spectrum analysis. The required Response Spectrum for main equipment of the primary coolant system of APR-1400 plant were considered to establish the enveloping response spectrum, which was applied to the seismic analysis model. The results from two seismic analysis methods were compared to show the structural adequacy of the metal insulator design against a safe shutdown earthquake. This study will form the basis for the seismic testing to support the seismic qualification of the reflective metal insulator.

• Nuclear Engineering and Technology
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• v.54 no.5
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• pp.1712-1725
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• 2022

For improving the seismic performance of the nuclear power plant (NPP) piping system, attempts have been made to apply a dynamic absorber (DA). However, the current piping DA design method is limited because it cannot provide the globally optimum values for the target design seismic loading. Therefore, this study proposes a seismic time history analysis-based DA optimal design method for piping. To this end, the Kriging approach is introduced to reduce the numerical cost required for seismic time history analyses. The appropriate design of the experiment method is used to increase the efficiency in securing response data. A gradient-based method is used to efficiently deal with the multi-dimensional unconstrained optimization problem of the DA optimal design. As a result, the proposed method showed an excellent response reduction effect in several responses compared to other optimal design methods. The proposed method showed that the average response reduction rate was about 9% less at the maximum acceleration, about 5% less at the maximum value of the response spectrum, about 9% less at the maximum relative displacement, and about 4% less at the maximum combined stress compared to existing optimal design methods. Therefore, the proposed method enables an effective optimal DA design method for mitigating seismic response in NPP piping in the future.

• Advances in environmental research
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• v.3 no.1
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• pp.11-28
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• 2014

Advanced oxidation processes using UV and catalysts like $TiO_2$ and ZnO have been recently applied for the photocatalytic degradation of MTBE in water. Attempts have been made to replace the UV radiation by the solar spectrum. This review intends to shed more light on the work that has been done so far in this area of research. The information provided will help in crystallizing the ideas required to shift the trend from UV photocatalysis to sunlight photocatalysis. The careful optimization of the reaction parameters and the type of the dopant employed are greatly responsible for any enhancement in the degradation process. The advantage of shifting from UV photocatalysts to visible light photocatalysts can be observed when catalysts like $TiO_2$ and ZnO are doped with suitable metals. Therefore, it is expected that in the near future, the visible light photocatalysis will be the main technique applied for the remediation of water contaminated with MTBE.

• Journal of Advanced Navigation Technology
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• v.21 no.4
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• pp.359-364
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• 2017

Since the existing analog village broadcasting system has some technical problems in applying and degradations in performance due to its old equipments, it had been required recently to be changed to a wireless digital system and to develop the standardization. However, it is important to analyze the interference between villages in deploying the efficient digital wireless village broadcasting system. In this paper, simulations for co-channel and adjacent channel interference have been carried out considering digital private mobile radio(dPMR) and digital mobile radio(DMR) systems as a representative mobile radio. These results for frequency reuse and channel separation drawn from the separation distance between villages in co-channel interference and the frequency offset in adjacent interference can be helpful to establish a standard and the testing service in the near future.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.85-85
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• 2013

Label-free, sensitive and selective detection methods with high spatial resolution are critically required for future applications in chemical sensor, biological sensor, and nanospectroscopic imaging. Here I describe the development of Plasmon Resonance Energy Transfer (PRET)-based molecular imaging in living cells as the first demonstration of intracellular imaging with PRET-based nanospectroscopy. In-vivo PRET imaging relied on the overlap between plasmon resonance frequency of gold nanoplasmonic probe (GNP) and absorption peak frequencies of conjugated molecules, which leads to create 'quantized quenching dips' in Rayleigh scattering spectrum of GNP. The position of these dips exactly matched with the absorption peaks of target molecules. As another innovative application of PRET, I present a highly selective and sensitive detection of metal ions by creating conjugated metal-ligand complexes on a single GNP. In addition to conferring high spatial resolution due to the small size of the metal ion probes (50 nm in diameter), this method is 100 to 1,000 folds more sensitive than organic reporter-based methods. Moreover, this technique achieves high selectivity due to the selective formation of Cu2+complexes and selective resonant quenching of GNP by the conjugated complexes. Since many metal ion ligand complexes generate new absorption peak due to the d-d transition in the metal ligand complex when a specific metal ion is inserted into the complex, we can match with the scattering frequency of nanoplasmonic metal ligand systems and the new absorption peak.

• Fashion & Textile Research Journal
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• v.6 no.4
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• pp.503-510
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• 2004

The study is one of fundamental researches for the development of future smart clothing and textile products with blocking properties from electromagnetic waves by analyzing human physical symptoms in using electromagnetic products in such an environments. Among various textiles in the experiment, nano silver has shown the best blocking performance from electromagnetic waves, which decreases depending on the distance. The power spectrum distribution and the incidence of electroencephalogram between blocking materials and aural stimuli has shown that, ${\beta}$, wave appeared to be active in all channels except for $T_4$, whereas all waves appeared with processed materials and especially with nano silver silk(NSS), ${\alpha}$, ${\beta}$, ${\theta}$, ${\gamma}$ waves appeared active in all regions. As for the brain mapping of ${\alpha}$ wave according to time, there found a strong activity in $P_3$, $P_4$ of the parietal lobe, with all materials on all time regions. With silk nylon metal(SNM) and NSS, it appeared strong in $F_3$, $F_4$ as well. As for ${\beta}$, wave, the activity appeared strong in frontal lobe before 7min. 30sec, where it tends to diminish abruptly in 7min. 30sec. to 13min. 30sec. region. After 13min., it regained gradually. With NSS, it appeared strong in all areas except for the farthest $T_4$. The appearance of ${\nu}$ wave can be deduced as it can affect human body with its toxic property while the silver particles become nano-sized. Therefore, the study conducted with human participants requires a proper particle size of it which would not penetrate cellular tissues and a proper binder and binding treatment for it, to prevent the physical fatigues and the potential diseases. However, it is highly required for back-up researches to verify various aspects in applying nano silver to textile products.

• Fashion & Textile Research Journal
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• v.6 no.6
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• pp.810-814
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• 2004

This study is one of the fundamental researches for the development of future smart clothing and textile products using silver(Ag) nano powder. Our study was focused on the blocking or insulating effects of nano-processed textiles from electromagnetic waves. Also, for the surveying of the actual effect to human body, we measure the variation of electroencephalogram which is an indication of human physical symptoms. Among various textiles in this experiment, nano silver processed case has shown the best blocking performance from the electromagnetic waves, which decreases depending on the distance. As a reference model of working environment, we setup the visual stimuli object on the computer that is a source of electromagnetic wave. The power spectrum distribution and the incidence of electroencephalogram was measured. The analysed data has shown that, with nano-processed textiles, ${\beta}$ wave does not appear very often where ${\beta}$ wave appears only to illustrate the stable states of human's body. However, as for the materials without nano processing, the ratio of ${\gamma}$ waves in the total level of electroencephalogram becomes higher in spite of short exposure to visual stimuli in work environment, which shows that the worker becomes stressed. The ${\beta}$ wave electroencephalogram of all materials is drawn in calcarine fissure of occipital lobe to show the convergent distribution, and stronger with block-processed Nano Silver Silk(NSS). The study based on the potential risks of human diseases such as physical fatigue by electromagnetic waves, and has shown that the application of Nano Silver textile for human uses require a proper particle size of it which would not penetrate cellular tissues, and a proper binder and binding treatment for it. However, it is highly required for back-up researches to verify various aspects in applying nano silver to textile products.

• Electronics and Telecommunications Trends
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• v.36 no.6
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• pp.36-45
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• 2021

As the global demand for satellite IoT services using small satellites increases, interest in their frequency requirements has also increased. Consequently, International Telecommunication Union Radiocommunication Sector (ITU-R) preparatory studies for WRC-23 include AI 1.18, which considers new frequency allocations for narrowband mobile satellites. This agenda item was issued in accordance with Resolution 284 (WRC-19), and contributions and reviews by government and satellite operators are underway at ITU-R SG4 WP4C with the aim of completing the study in 2023. Resolution 248 (WRC-19) considers the conditions for transmission of candidate bands and satellites and terminals for narrowband mobile satellite, and all contributions should satisfy narrowband mobile satellite system characteristics parameters within these conditions. However, among the current transmission specifications, there are several views on the exact definition of satellite e.i.r.p., and the derivation schedule of characteristic system parameters for the study is slower than that of the original work schedule. The goal of this paper is to examine the outline of WRC-23 AI 1.18 and the main content of Resolution 284 (WRC-19) and to determine the status of studies related to WRC-23 AI 1.18. The ITU-R's study on this agenda includes updating work schedules, developing the draft required spectrum and system characteristics parameter reports/recommendations, developing draft CPM reports, and examining the various views of transmission specifications in Resolution 284 (WRC-19). Focusing on candidate bands in Region 1 (Europe and Africa) and Region 2 (America), the current status of use in Korea is investigated and future countermeasures in Korea are investigated. In addition, we would like to examine the trend of narrowband mobile satellite through satellite frequency and service status and planning of satellite IoT operators, such as EchoStar, Omnispace, and Sateliot that are participating in the ITU-R study.