• 제목/요약/키워드: reproducibility of results

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게이트 심근 SPECT를 이용한 비침습적 심실 수축력 측정방법의 재현성 (Reproducibility of non-invasive measurement for left ventricular contractility using gated myocardial SPECT)

  • 김경민;이동수;김유경;천기정;김석기;정준기;이명철
    • 대한핵의학회지
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    • 제35권3호
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    • pp.152-160
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    • 2001
  • 목적: 게이트 심근 SPECT를 이용하여 좌심실심근의 최대탄성률을 측정하는 방법의 재현성을 조사하고 단일 압력-부피 고리방법과 매개변수 최적화 방법으로 얻었을 때 재현성의 차이를 조사하였다. 대상 및 방법: 관상동맥질환이 의심되는 47명 (남자 42명, 여자 5명, 평균나이 53세, 좌심실구혈률 22-68%)에서 Tc-99m MIBI게이트 심근 SPECT와 동시에 요골동맥 긴장도를 측정하였다. 이 중 11명에서는 누운 자리에서 움직이지 않고 연이어 두번 측정하였다. 최대탄성률과 영점부피를 Lee 등이 제안한 단일 압력-부피 고리 방법과 Yoshizawa 등이 제안한 선형근사에 의한 매개변수 최적화 방법으로 추정하였다. 결과: 최대탄성률(상관계수 0.96)과 영점부피(상관계수 0.99)의 재현성은 단일 압력-부피 고리 방법이 매개변수 최적화 방법(최대탄성률 0.89, 영점부피 0.64)보다 좋았다. 두 방법으로 추정한 최대탄성률의 상관계수는 0.77, 영점부피의 상관계수는 0.65이었다. 결론: 게이트 심근 SPECT와 동맥긴장도 측정법으로 얻어 단일 압력-부피 고리 방법으로 추정한 좌심실 심근의 최대탄성률의 재현성은 매우 우수하였다. 매개변수 최적화 방법으로 얻은 최대탄성률도 우수하나 단일 압력-부피 고리 방법보다 못하였다.

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Reproducibility of lateral cephalometric landmarks on conventional radiographs and spatial frequency-processed digital images

  • Shin Jeong-Won;Choi Hang-Moon;Heo Min-Suk;Lee Sam-Sun;Choi Hyun-Bae;Choi Soon-Chul
    • Imaging Science in Dentistry
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    • 제32권4호
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    • pp.213-219
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    • 2002
  • Purpose : Computed radiography (CR) has been used in cephalometric radiography and many studies have been carried out to improve image quality using various digital enhancement and filtering techniques, During CR image acquisition, the frequency rank and type affect to the image quality. The aim of this study was to compare the diagnostic quality of conventional cephalometric radiographs to those of computed radiography. Materials and Methods : The diagnostic quality of conventional cephalometric radiographs (MO) and their digital image counterparts were compared, and at the same time, six modalities (M1-M6) of spatial frequency-processed digital images were compared by evaluating the reproducibility of 23 cephalometric landmark locations. Reproducibility was defined as an observer's deviation (in mm) from the mean between all observers. Results and Conclusion: In comparison with the conventional cephalometric radiograph (MO), Ml showed statistically significant differences in 8 locations, M2 in 9, M3 12, M4 in 7, M5 in 12, and M6 showed significant differences in 14 of 23 landmark locations (p < 0.05). The number of reproducible landmarks that each modality possesses were 7 in M6, 6 in M5, 5 in M3, 4 in M4, 3 in M2, 2 in Ml, and 1 location in MO. The image modality that observers selected as having the best image quality was M5.

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Evaluation of the reproducibility of various abutments using a blue light model scanner

  • Kim, Dong-Yeon;Lee, Kyung-Eun;Jeon, Jin-Hun;Kim, Ji-Hwan;Kim, Woong-Chul
    • The Journal of Advanced Prosthodontics
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    • 제10권4호
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    • pp.328-334
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    • 2018
  • PURPOSE. To evaluate the reproducibility of scan-based abutments using a blue light model scanner. MATERIALS AND METHODS. A wax cast abutment die was fabricated, and a silicone impression was prepared using a silicone material. Nine study dies were constructed using the prepared duplicable silicone, and the first was used as a reference. These dies were classified into three groups and scanned using a blue light model scanner. The first three-dimensional (3D) data set was obtained by scanning eight dies separately in the first group. The second 3D data set was acquired when four dies were placed together in the scanner and scanned twice in the second group. Finally, the third 3D data set was obtained when eight dies were placed together in the scanner and scanned once. These data were then used to define the data value using third-dimension software. All the data were then analyzed using the non-parametric Kruskal-Wallis H test (${\alpha}=.05$) and the post-hoc Mann-Whitney U-test with Bonferroni's correction (${\alpha}=.017$). RESULTS. The means and standard deviations of the eight dies together were larger than those of the four dies together and of the individual die. Moreover, significant differences were observed among the three groups (P<.05). CONCLUSION. With larger numbers of abutments scanned together, the scan becomes more inaccurate and loses reproducibility. Therefore, scans of smaller numbers of abutments are recommended to ensure better results.

맥솔(脈率) 측정방법(測定方法)의 신뢰도(信賴度) 분석(分析) (The Analysis on the Reliability of Measuring Pulse-Respiration Ratio)

  • 김동훈;양동훈;허웅;박영재;박영배
    • 대한한의진단학회지
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    • 제9권2호
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    • pp.123-144
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    • 2005
  • Objectives: Pulse-Respiration Ratio has been used for estimating subject's Han-Yeol [寒熱] status since it mentioned in suwen [素問]. In practicing Pulse-Respiration Ratio over 5 means the status of Yeol [熱], Pulse-Respiration Ratio below 3 means the status of Han [寒]. We performed this study to examine the Optimum Standard for Measuring Pulse-Respiration Ratio on the Basis of Repeatability and Reproducibility. Methods: After subject's 5 minutes rest we measured subject's ECG, respiration pattern, EEG, EMG simultaneously. In this research examiner's number is two, subject's number is four, and the number of repeat is two. We calculated Pulse-Respiration Ratio through dividing Respiration cycle average by Pulse cycle average according to each standard including time section, $EEG(relative-{\alpha}$ density, $relative-{\beta}$ density, ${\alpha}/{\beta}$ and EMG. We analyzed these data through Gage R&R study using MINITAB 13.20 program and considered the results of below 30 %R&R and over 4 Number of Distinct Categories to have a significance. Results: 1. In the applying of time standard, Pulse-Respiration Ratio from section 3, 4, 6, 8 had a significant meaning in the aspect of Repeatability and Reproducibility. 2. In the applying of $EEG({\alpha}$ I , ${\beta}$ I , ${\alpha}/{\beta})$, EMG(E I) standard, there was no significant results. 3. In the applying of time standard(section 5, 6, 7), $EEG({\alpha}$ I , ${\beta}$ I , ${\alpha}/{\beta})$ and EMG(E I) standard simultaneously, Pulse-Respiration Ratio from ${\alpha}/{\beta}$ in section 6, ${\beta}$ I in section 8 had a significant meaning in the aspect of Repeatability and Reproducibility. Conclusions: We can suggest the Optimum Standard for Measuring Pulse-Respiration Ratio on the basis of Repeatability and Reproducibility as followings; 1. Pulse-Respiration Ratio Measuring time should be at least 15 minutes. 2. Applying of time(section 6, 8) and $EEG({\beta}$ I, ${\alpha}/{\beta})$ standard simultaneously is recommended considering reliability and validity but more study is needed. 3. EMG(E I) may be helpful to detect the segment of physical rest and exclude artifacts but more study is needed.

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스테레오 카메라를 이용한 안면부 측정의 재현성과 정확도에 대한 마네킨을 이용한 연구: 직접 인체계측, Digitizer, Stereophotogrammetry의 비교 연구 (Manikin Model Study on Reproducibility and Accuracy of Maxillofacial Measurements Determined by Stereocamera: Comparative Study of Direct Anthropometry, Digitizer and Stereophotogrammetery)

  • 정연욱;양지웅;정광;국민석;오희균
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제34권1호
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    • pp.17-25
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    • 2012
  • Purpose: Recently, a three dimensional approach to hard and soft tissues of the maxillofacial area has been widely used. This study was to evaluate the reproducibility and accuracy of a stereocamera compared to actual measurement methods using a digital caliper and digitizer. Methods: The stereoscopies of 7 head dummies with different sizes and shapes were obtained using a Di3D system (Dimensional Imaging, Glasgow, UK) after marking reference points on facial areas. From the obtained stereoscopy, 10 measurements representing the width, height and depth of each of the facial sections of the dummy were measured twice using a three dimensional reverse engineering software program (RapidForm$^{TM}$ 2006, Inus, Seoul, Korea). The x, y, and z coordinates of each of the three dimensional measurements were obtained and distances between two points were calculated. All procedures were repeated twice. The actual measurement method was performed twice, directly on dummies, using a digital caliper and values were compared with the previously determined values. Results: The results were as follows. In the ANOVA analysis, there were no significant statistical differences among the three measurement methods. In the Bonferroni analysis, with adjustments applied for multiple comparisons, there was no difference between actual measurement methods using a digitizer and a digital caliper. However, there was some difference between using a stereocamera and actual measurement methods using a digitizer and a digital caliper in values of $Ex_{Rt}-Ex_{Lt}$, $En_{Rt}-En_{Lt}$, $Ala_{Rt}-Ala_{Lt}$, $Ch_{Rt}-Ch_{Lt}$, G-Pg', $Ala_{Rt}$-Prn, $Ala_{Rt}$-Prn. The mean value for technical error in measurement (TEM) in Di3D (0.98 mm) was slightly higher than for a digital caliper (0.17 mm) and a digitizer (0.30 mm). In an intraclass correlation coefficient (ICC) there were no significant differences among the three measurement methods, but the Di3D system with the stereocamera showed relatively lower reproducibility compared to actual measurement methods using a digitizer and a digital caliper. Conclusion: These results indicate that some complementary measures may be needed to improve accuracy and reproducibility in the Di3D system with stereocamera.

게이트 Tc-99m-MIBI SPECT에서 국소 심근운동과 수축기 심근두꺼워짐 자동정량화법의 재현성 (Reproducibility of an Automatic Quantitation of Regional Myocardial Wall Motion and Systolic Thickening on Gated Tc-99m-MIBI Myocardial SPECT)

  • 팽진철;이동수;천기정;김유경;정준기;이명철
    • 대한핵의학회지
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    • 제34권6호
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    • pp.487-496
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    • 2000
  • 목적: 국소 심근 벽 운동과 수축기 심근두꺼워짐에 대한 자동정량화 소프트웨어의 재현성을 알아보고자 하였다. 대상 및 방법: 31명의 무작위 추출한 관상동맥질 환자에서 부하 게이트 Tc-99m-MIBI SPECT를 시행하는 중에, 게이트 심근 SPECT를 1회 시행한 이후 바로 이어 한번 더 게이트 SPECT를 시행하였다. 얻어진 영상으로부터 AutoQUANT 소프트웨어를 이용하여 분절별, 심근벽별로 심근벽 운동과 수축기 심근두꺼워짐의 자동정량값을 얻어, 1회째 값과 2회째 값 사이의 상관계수를 계산하고 Bland-Altman 도표를 통해 변이의 범위를 보았다. 또 각 값들을 등급화한 수치 간에 kappa 값을 구해보았다. 결과: 재현성 분석에서 1회와 2회 시행간의 상관계수는 각각 0.948, 0.878이었으며, weighted kappa 값은 0.807, 0.708로 아주 좋은 일치도를 보였다. Bland-Altman 분석에서 변이의 2 표준편차 범위는 각각 ${\pm}2.0mm,\;{\pm}20.2%$였다. 각각의 재현성은 분절영역, 성별, 관류의 수준에 따라 차이를 보이지 않았다. 결론: 이 연구에서 우리는, 심근 벽 운동과 수축기 심근두꺼워짐의 자동정량화 소프트웨어가 좋은 재현성을 가지고 있음을 알았으며, 또한 추적 검사나 치료효과 판정시 심근 벽 운동과 수축기 심근두꺼워짐의 변화 판정 기준을 마련하였다.

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Comparative Study between ZOOMit and Conventional Intravoxel Incoherent Motion MRI for Assessing Parotid Gland Abnormalities in Patients with Early- or Mid-Stage Sjögren's Syndrome

  • Qing-Qing Zhou;Wei Zhang;Yu-Sheng Yu;Hong-Yan Li;Liang Wei;Xue-Song Li;Zhen-Zhen He;Hong Zhang
    • Korean Journal of Radiology
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    • 제23권4호
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    • pp.455-465
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    • 2022
  • Objective: To compare the reproducibility and performance of quantitative metrics between ZOOMit and conventional intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) in the diagnosis of early- and mid-stage Sjögren's syndrome (SS). Materials and Methods: Twenty-two patients (mean age ± standard deviation, 52.0 ± 10.8 years; male:female, 2:20) with early- or mid-stage SS and 20 healthy controls (46.9 ± 14.6 years; male:female, 7:13) were prospectively enrolled in our study. ZOOMit IVIM and conventional IVIM MRI were performed simultaneously in all individuals using a 3T scanner. Quantitative IVIM parameters - including tissue diffusivity (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) - inter- and intra-observer reproducibility in measuring these parameters, and their ability to distinguish patients with SS from healthy individuals were assessed and compared between ZOOMit IVIM and conventional IVIM methods, appropriately. MR gland nodular grade (MRG) was also examined. Results: Inter- and intra-observer reproducibility was better with ZOOMit imaging than with conventional IVIM imaging (ZOOMit vs. conventional, intraclass correlation coefficient of 0.897-0.941 vs. 0.667-0.782 for inter-observer reproducibility and 0.891-0.968 vs. 0.814-0.853 for intra-observer reproducibility). Significant differences in ZOOMit f, ZOOMit D*, D*, conventional D*, and MRG between patients with SS and healthy individuals (all p < 0.05) were observed. ZOOMit D* outperformed conventional D* in diagnosing early- and mid-stage SS (area under receiver operating curve, 0.867 and 0.658, respectively; p = 0.002). The combination of ZOOMit D*, MRG, and ZOOMit f as a new diagnostic index for SS, increased diagnostic area under the curve to 0.961, which was higher than that of any single parameter (all p < 0.01). Conclusion: Considering its better reproducibility and performance, ZOOMit IVIM may be preferred over conventional IVIM MRI, and may subsequently improve the ability to diagnose early- and mid-stage SS.

하악골운동 추적을 위한 단순기록장치 고안에 관한 연구 (A STUDY ON THE DESIGN OF SIMPLE RECORDING DEVICE TO TRACE THE MANDIBULAR MOVEMENTS)

  • 김상수;윤창근
    • 대한치과보철학회지
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    • 제25권1호
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    • pp.253-267
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    • 1987
  • The purpose of this study was to improve limitations and disadvantages of the mechanical pantograph and the Visi-Trainer, and to design the reliable and reproducible device mandibular movement tracking device (MMTD) that is more simple, convenient and save the chair time than the mechanical pantograph and Visi-Trainer. MMTD was consist of head frame, horizontal bar, condylar path tracking stylus holders, anterior path tracking stylus holder, two condylar path plastic recording plates, one anterior path plastic recording plate, toggles and open occlusal clutch. To prove the reliability and reproducibility of MMTD, a five adults were selected and mandibular condylar movement was recorded one time by the mechanical pantographic tracing and MMTD. The border movement recording of the mandibular incisor (frontal, sagittal and horizontal) was also recorded by Visi-Trainer and the MMTD. The obtained results were as follows; 1. The condylar movement path (sagittal, horizontal) of the MMTD was not coincidence with that of mechanical pantograph. 2. Measurements of the angulation which established between working and balancing path records by use of the mechanical pantograph and MMTD, there was no significance. 3. In a view of MMTD's reproducibility, there was revealed almost similar recording pattern. 4. The border movement recording of the mandibular incisor by the MMTD and the Visi-Trainer showed almost same reliability and reproducibility. 5. The subjects were able to his original mandibular movements by use of open occlusal clutch in the MMTD.

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Performance Evaluation of the Automated Fluorescent Immunoassay System Rotavirus Assay in Clinical Samples

  • Kim, Jae-Seok;Lee, Su-Kyung;Ko, Dae-Hyun;Hyun, Jungwon;Kim, Hyun Soo
    • Annals of Laboratory Medicine
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    • 제39권1호
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    • pp.50-57
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    • 2019
  • Background: The Automated Fluorescent Immunoassay System (AFIAS) rotavirus assay (Boditech Med Inc., Chuncheon, Korea) is a new rapid antigen test for rotavirus detection. We evaluated the performance of this assay for detecting rotaviruses and their specific genotypes in clinical stool samples. Methods: AFIAS rotavirus assay was performed in 103 rotavirus-positive and 103 rotavirus-negative stool samples (confirmed by both PCR and ELISA), and its results were compared with those of PCR, ELISA, and immunochromatographic assay (ICA). We evaluated diagnostic sensitivity/specificity, the detectability of rotavirus subtypes, lower limit of detection (LLOD), reproducibility, cross-reactivity, and interference of AFIAS rotavirus assay. Results: Based on PCR and ELISA results, diagnostic sensitivity and specificity of the AFIAS rotavirus assay were both 99.0%. LLOD results showed that the AFIAS assay had sensitivity similar to or greater than ICA and ELISA. High reproducibility was confirmed, and no cross-reactivity or interference was detected. This assay could detect genotypes G1P[8], G2P[4], G3P[8], G4P[6], G4P[8], G8P[4], G8P[8], G9P[4], and G9P[8]. Conclusions: The AFIAS rotavirus assay showed high reproducibility, sensitivity, and specificity as well as excellent agreement with ELISA, PCR, and ICA. It detected the most common as well as unusual genotypes of rotavirus prevalent in Korea. It could be a useful onsite assay for rapid, convenient, and cost-effective detection of rotavirus infection.

Reproducibility of Electromyography Signal Amplitude during Repetitive Dynamic Contraction

  • Mo, Seung-Min;Kwag, Jong-Seon;Jung, Myung-Chul
    • 대한인간공학회지
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    • 제30권6호
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    • pp.689-694
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    • 2011
  • Objective: The aim of this study is to evaluate the fluctuation of signal amplitude during repetitive dynamic contraction based on surface electromyography(EMG). Background: The most previous studies were considered isometric muscle contraction and they were difference to smoothing window length by moving average filter. In practical, the human movement is dynamic state. Dynamic EMG signal which indicated as the nonstationary pattern should be analyzed differently compared with the static EMG signal. Method: Ten male subjects participated in this experiment, and EMG signal was recorded by biceps brachii, anterior/posterior deltoid, and upper/lower trapezius muscles. The subject was performed to repetitive right horizontal lifting task during ten cycles. This study was considered three independent variables(muscle, amplitude processing technique, and smoothing window length) as the within-subject experimental design. This study was estimated muscular activation by means of the linear envelope technique(LE). The dependent variable was set coefficient of variation(CV) of LE for each cycle. Results: The ANOVA results showed that the main and interaction effects between the amplitude processing technique and smoothing window length were significant difference. The CV value of peak LE was higher than mean LE. According to increase the smoothing window length, this study shows that the CV trend of peak LE was decreased. However, the CV of mean LE was analyzed constant fluctuation trend regardless of the smoothing window length. Conclusion: Based on these results, we expected that using the mean LE and 300ms window length increased reproducibility and signal noise ratio during repetitive dynamic muscle contraction. Application: These results can be used to provide fundamental information for repetitive dynamic EMG signal processing.