• Biomolecules & Therapeutics
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• v.14 no.3
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• pp.125-131
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• 2006

The inhibitory effects of (-)-epigallocatechin gallate (EGCG), a major compound of green tea, on the development of locomotor sensitization, conditioned place preference (CPP) and dopamine receptor supersensitivity induced by the repeated administration of morphine were investigated in mice. A single administration of morphine produces hyperlocomotion. The repeated administration of morphine develops sensitization, a progressive enhancement of locomotion, which is used as a model for studying the craving and drug-seeking behaviors characterizing addiction, and CPP, which is used as a model for studying drug reinforcement, respectively. EGCG inhibited morphine-induced hyperlocomotion, sensitization and CPP. In addition, EGCG inhibited the development of postsynaptic dopamine receptors supersensitivity, which may be an underlying common mechanism that mediates the morphine-induced dopaminergic behaviors such as sensitization and CPP. Apomorphine (a dopamine agonist)-induced climbing behaviors also were inhibited by a single direct administration of EGCG These results provide evidence that EGCG has anti-dopaminergic activity, as inhibiting the development of dopamine receptor supersensitivity and apomorphine-induced climbing behaviors. Therefore, it is suggested that green tea may be useful for the prevention and therapy of these adverse actions of morphine.

• Journal of the Korean Society of Clothing and Textiles
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• v.38 no.5
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• pp.665-674
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• 2014

An analysis of the components of clay mineral before and after coloration (XRF) showed that the elements involved in coloration are Fe, Cr, and Ni. Fe accounts for 65% of coloring components on dyed fabric; in addition, Cr and Ni also affect coloring. The optimal coloration condition was to repeat the process of immersing the cotton fabric in $80^{\circ}C$ slurry of 8g of clay mineral to 1g cotton for 60 minutes, dry it for 24 hours and rinse three times. Especially, as the repetition of coloration increased, the $(K/S)_{440}$ value of sample A increased from 1.0 to 2.5, and sample B increased from 1.0 to 1.6. The effect of the repeated process on coloration was significant; consequently, the rinsing and drying process were important to decrease the coloration level. It also showed excellent results in regard to color fastness to washing, light, rubbing, perspiration, and antibiotic effect.

• Clinical and Experimental Reproductive Medicine
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• v.43 no.4
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• pp.185-192
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• 2016

Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-existence between microorganisms and the host immune system in the endometrium. A majority of CE cases produce no noticeable signs or mild symptoms, and the prevalence rate of CE has been found to be approximately 10%. Gynecologists and pathologists often do not focus much clinical attention on CE due to the time-consuming microscopic examinations necessary to diagnose CE, its mild clinical manifestations, and the benign nature of the disease. However, the relationship between CE and infertility-related conditions such as repeated implantation failure and recurrent miscarriage has recently emerged as an area of inquiry. In this study, we reviewed the literature on the pathophysiology of CE and how it may be associated with infertility, as well as the literature regarding the diagnosis and treatment of CE. In addition, we discuss the value of hysteroscopic procedures in the diagnosis and treatment of CE.

• Archives of Pharmacal Research
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• v.29 no.10
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• pp.904-910
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• 2006

The inhibitory effects of paeonol, a major compound of Paeoniae radix, on the development of locomotor sensitization, conditioned place preference (CPP) and dopamine receptor supersensitivity induced by the repeated administration of morphine were investigated through behavioral experiments. A single administration of morphine produces hyperlocomotion. Repeated administration of morphine develops sensitization (reverse tolerance), a progressive enhancement of locomotion, which is used as a model for studying the drug-induced drug-seeking behaviors, and CPP, which is used as a model for studying drug reinforcement. Paeonol inhibited morphine-induced hyperlocomotion, sensitization and CPP. In addition, paeonol inhibited the development of postsynaptic dopamine receptors supersensitivity, which may be an underlying common mechanism that mediates the morphine-induced dopaminergic behaviors such as sensitization and CPP. Apomorphine (a dopamine agonist)-induced climbing behaviors also were inhibited by a single direct administration of paeonol. These results provide evidence that paeonol exerts anti-dopaminergic activity, and it is suggested that paeonol may be useful for the prevention and therapy of these adverse actions of morphine.

• Journal of the Korean Society of Clothing and Textiles
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• v.42 no.3
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• pp.474-485
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• 2018

Smart sensors and connected devices have changed the concept of garments along with IT technology convergent garments that transform the performance of basic functions. Various types of products have been researched and developed due to the increased interest in smart clothing; in addition, studies based on physical and mechanical properties have also been actively studied to improve accuracy and reliability. This study represents a basic study for the development of smart textiles based on motion recognition for the surfing practice of beginners interested in IT convergence type. A physical durability evaluation of conductive yarn according to sewing method was later carried out. This study is a conditional specimen sewn with cotton lower thread and 100mm pattern length based on the results of previous studies. The durability of the conductive yarn according to the sewing method was evaluated according to the sewing method. Durability was evaluated by two kinds of repeated strain and abrasion tests. The specimen with applied cotton in a lower thread zigzag pattern 2mm stitch size 100mm stitch length was shown to have the most suitable durability for smart textile.

• Journal of Fashion Business
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• v.17 no.2
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• pp.179-196
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• 2013

This research is about the mechanical properties of knit pullover of Shaping and WholeGarment according to structured patterns and form of the armhole. For the study 12 samples are prepared under different conditions and through comparative analysis of each sample's armhole around armpit in basic properties, tensile strength & elongation and residual elongation after repeated extensions, the conclusion is as follows. As a result of comparing basic properties of structured pattern of Shaping and WholeGarment samples, in all structured patterns Shaping samples weighed more. According to the comparative analysis of tensile strength & elongation of Shaping and WholeGarment samples, Machi on both sides of WholeGarment samples showed the highest strength. By comparing outcome of residual elongation by structured pattern of Shaping and WholeGarment samples, both types were observed to have the residual elongation increase in the order of Plain

• The Journal of Korean Physical Therapy
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• v.26 no.3
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• pp.191-195
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• 2014

Purpose: The purpose of this study is to investigate whether types of sensory-stimuli cues in terms of visual, auditory, and visuoauditory cues can be affected to motor sequential learning in healthy adults, using serial reaction time task. Methods: Twenty four healthy subjects participated in this study, who were randomly allocated into three groups, in terms of visual-stimuli (VS) group, auditory-stimuli (AS) group, and visuoauditory-stimuli (VAS) group. In SRT task, eight Arabic numbers were adopted as presentational stimulus, which were composed of three different types of presentational modules, in terms of visual, auditory, and visuoauditory stimuli. On an experiment, all subjects performed total 3 sessions relevant to each stimulus module with a pause of 10 minutes for training and pre-/post-tests. At the pre- and post-tests, reaction time and accuracy were calculated. Results: In reaction time, significant differences were founded in terms of between-subjects, within-subjects, and interaction effect for group ${\times}$ repeated factor. In accuracy, no significant differences were observed in between-group and interaction effect for groups ${\times}$ repeated factor. However, a significant main effect of within-subjects was observed. In addition, a significant difference was showed in comparison of differences of changes between the pre- and post-test only in the reaction time among three groups. Conclusion: This study suggest that short-term sequential motor training on one day induced behavioral modification, such as speed and accuracy of motor response. In addition, we found that motor training using visual-stimuli cue showed better effect of motor skill acquisition, compared to auditory and visuoauditory-stimuli cues.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.4
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• pp.315-319
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• 2009

Astragalus Membranaceus (AM) is a useful Korean herb that has been clinically prescribed for stress-related illness. The objective of the present study was to examine the anti-stress effects of AM on repeated stress-induced alterations of anxiety, learning and memory in rats. Restraint stress was administered for 14 days (2h/day) and AM (400mg/kg) given by oral administration, in the AM group, for the same period. Starting on the eighth day, the rats were tested for spatial memory on the Morris water maze test (MW) and for anxiety on the elevated plus maze (EPM). Changes of expression on immunohistochemistry were studied for cholineacetyl transferase (ChAT) and tyrosine hydroxylase (TH) in the brain. The results showed that the rats treated with AM had significantly reduced stress-induced deficits on learning and memory on the spatial memory tasks. In addition, the ChAT immunoreactivities were increased. In the EPM, treatment with AM increased the time spent in the open arms (p<0.001) compared to the control group. In addition, AM treatment also normalized increases of TH expression in the LC (p<0.001). In conclusion, administration of AM improved spatial learning and memory and reduced stress-induced anxiety. Thus, the present results suggest that AM is able to recover behavioral and neurochemical impairments induced by stress.

• The Korean Journal of Applied Statistics
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• v.31 no.5
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• pp.587-597
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• 2018

Procedures, such as sampling technique, survey method, and questionnaire preparation, are required in order to obtain sample data in accordance with the purpose of a survey. An important procedure is the decision of the sample size formula. The sample size formula is determined by setting the target error and total cost according to the sampling method. In this paper, we propose a sample size formula using population changes over time, estimation error of the previous time and response rate of past data when the target error and the expected response rate are given in the simple random sampling. In actual research, we use estimators that apply complex weights in addition to design-based weights. Therefore, we induce a sample size formula for estimators using design-based weights and nonresponse adjustment coefficients, that can be a formula that reflects differences in response rates when survey methods are changed over time. In addition, we use simulations to compare the proposed formula with the existing sample size formula.

• Communications of Mathematical Education
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• v.20 no.3 s.27
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• pp.443-467
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• 2006

The purpose of this study was to study the 2nd grade elementary students' common thinking and differences of additive and multiplicative thinking. For meaningful discussion of the above, we have established the following research questions. 1. What are the properties of the multiplicative thinking of 2nd grade elementary students? - What are the common properties of the multiplicative thinking of 2nd grade elementary students? - What are the properties of the various multiplicative thinking levels? 2. How is multiplicative thinking presented in Korean math textbooks? The conclusions of this study were followings: First, the 2nd grade elementary students in the multiplicative thinking learnt used by translating multiplication into specific situations. And they often used different models of multiplication. Second, additive thinking developed into the multiplicative thinking. After being helped by their teachers, students who thought additively were then able to think multiplicatively. Whereas after being helped by their teachers, students who were already competent at multiplicative thinking gained a deeper understanding. Third, they learned the commutative property of multiplication after their understanding of the 'repeated addition approach' and the multiplicative approach was sufficiently reinforced. Last, students should be taught using different models based on the repeated addition approach.