• Steel and Composite Structures
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• v.37 no.4
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• pp.419-429
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• 2020

Composite structures are generally pressurized at both sides when repaired by the scarf repair method. But single-face vacuum bag curing (SVC) may be used in some practical scarf repair of penetration damage due to the low accessibility of composite structures, which can decrease bonding quality and may reduce structural mechanical properties. In this paper, experimental investigations were conducted on tensile and compressive properties of scarf-repaired composite laminates using SVC and double-face vacuum bag curing (DVC) in four hygrothermal environments. Finite element models of composite scarf joints with voids were established to further explore the failure mechanism of scarf-repaired laminates. Results show that the curing condition hardly affects tensile and compressive properties of the repaired laminates though it significantly affects the bonding quality with adhesive inner voids. Failure loads of scarf joints almost keep unchanged with adhesive voids increasing.

• Advances in concrete construction
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• v.9 no.1
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• pp.1-7
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• 2020

Retrofitting is an alteration of existing member or component of the structure. In civil engineering point of view, it is called strengthening of the old structure. Deterioration of structures may be due to aging, corrosion, failure of joints, earthquake forces, increase in service loads, etc. Such structures need urgent repair, retrofitting and strengthening to avoid collapse, cracking and loss in strength or deflection. Advanced techniques are required to be developed for the repair of structural components to replace conventional techniques. This paper focuses exclusively on torsional behaviour of Reinforced Concrete (RC) beams and retrofitted RC beams wrapped with aramid fiber. Beams were retrofitted with aramid fiber by full wrapping and in the form of 150 mm wide strips at a spacing of 100 mm, 150 mm, 200 mm respectively using epoxy resin and hardener. A total 15 numbers of RC beams of 150 mm×300 mm×1300 mm in size were cast, 3 beams are tested as control specimens, and 12 beams are tested for torsion up to the failure and then retrofitted with aramid fiber. Experimental results are validated with the help of data obtained by finite element analysis using ANSYS. The full wrapping configuration of aramid fiber regains 105% strength after retrofitting. With the increase in spacing of fabric material, torsional strength reduces to 82% with about 45% saving in material.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.8 s.179
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• pp.2000-2006
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• 2000

The enhancement of service life of damaged or cracked structures is currently major issue to the researchers and engineers. In order to improve the life of cracked aging aircraft structures, the repair technique which uses adhesively bonded boron/epoxy composite patches is being widely considered as a cost-effective and reliable method. This paper is to study the performance of the bonded composite patch repair of a plate containing an inclined central through-crack. A 3-dimensional finite element method having three layers to the cracked plate, composite patch and adhesive layer, is used to compute the stress intensity factor. In this paper, the reduction of stress intensity factors near the crack-tip are determined to evaluate the effects of various non-dimensional design parameter including composite patch thickness, and material properties of the composite patch and thickness of the adhesive layer, materials of patch etc., and the crack length, Finally, The problem of how to optimize the patch geometric configurations has been discussed.

• Journal of the Korean Recycled Construction Resources Institute
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• v.3 no.1
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• pp.65-71
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• 2007

Since pop-outs are occurred recently on concrete surface occasionally, it is needed to find out accurate causes and to suggest appropriate methods. On this study, it is investigated the occurrence mechanism of pop-outs caused by electric arc furnace Oxidizing slags as fine aggregate for concrete. As a result, it is investigated the cause of pop-outs that extremely small quantities of free CaO and free MgO in the electric furnace slag react with water to produce $Ca(OH)_2$ and $Mg(OH)_2$, so that their volumes are expanded and erupted about two times. As a resolution, it is needed to remove the potential cause of expansion by replacing the deteriorated concrete section up to the depth to secure the safe of structural element with repairing polymer mortar, especially more than 50MPa.

• Journal of Chest Surgery
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• v.31 no.9
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• pp.899-902
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• 1998

Recent advances in understanding the anatomy of complete atrioventricular septal defect have led to alternative methods of repairing these defects. Here we report two cases of complete atrioventricular septal defect repair by direct closure of the ventricular element of the defect. Follow-up for average of 3 months suggests that, when direct closure can be performed, the results can be comparable with those of the standard technique. Our initial success with this approach is encouraging; however, longer follow-up and more experiences are required to establish whether it will be broadly applicable.

• Structural Engineering and Mechanics
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• v.84 no.6
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• pp.799-811
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• 2022

Adhesive bonding has seen rapid development in recent years, with emphasis to composite patch repairing processes of geometric defects in aeronautical structures. However, its use is still limited given its low resistance to climatic conditions and requirement of specialized labor to avoid fabrication induced defects, such as air bubbles, cracks, and cavities. This work aims to numerically analyze, by the finite element method, the failure behavior of a damaged plate, in the form of a bonding defect, and repaired by an adhesively bonded composite patch. The position and size of the defect were studied. The results of the numerical analysis clearly showed that the position of the defect in the adhesive layer has a large effect on the value of J-Integral. The reduction in the value of J-Integral is also related to the composite stacking sequence which, according to the mechanical properties of the ply, provides better load transfer from the plate to the repair piece through the adhesive. In addition, the increase in the applied load significantly affects the value of the J-Integral at the crack tip in the presence of a bonding defect, even for small dimensions, by reducing the load transfer.

• BMB Reports
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• v.56 no.11
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• pp.612-617
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• 2023

Pleiotropic regulator 1 (PLRG1), a highly conserved element in the spliceosome, can form a NineTeen Complex (NTC) with Prp19, SPF27, and CDC5L. This complex plays crucial roles in both pre-mRNA splicing and DNA repair processes. Here, we provide evidence that PLRG1 has a multifaceted impact on cancer cell proliferation. Comparing its expression levels in cancer and normal cells, we observed that PLRG1 was upregulated in various tumor tissues and cell lines. Knockdown of PLRG1 resulted in tumor-specific cell death. Depletion of PLRG1 had notable effects, including mitotic arrest, microtubule instability, endoplasmic reticulum (ER) stress, and accumulation of autophagy, ultimately culminating in apoptosis. Our results also demonstrated that PLRG1 downregulation contributed to DNA damage in cancer cells, which we confirmed through experimental validation as DNA repair impairment. Interestingly, when PLRG1 was decreased in normal cells, it induced G1 arrest as a self-protective mechanism, distinguishing it from effects observed in cancer cells. These results highlight multifaceted impacts of PLRG1 in cancer and underscore its potential as a novel anti-cancer strategy by selectively targeting cancer cells.

• Structural Engineering and Mechanics
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• v.47 no.4
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• pp.575-598
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• 2013

The study presents the results of an experimental program concerning the shear force transfer between reinforced concrete (RC) jackets and existing columns with damages. In order to investigate the effectiveness of the repair method applied and the contribution of each shear transfer mechanism of the interface. It includes 22 concrete columns (core) (of 24,37MPa concrete strength) with square section (150mm side, 500 mm height and scale 1:2). Ten columns had initial construction damages and twelve were subjected to initial axial load. Sixteen columns have full jacketing at all four faces with 80mm thickness (of 31,7MPa concrete strength) and contain longitudinal bars (of 500MPa nominal strength) and closed stirrups spaced at 25mm, 50mm or 100mm (of 220MPa nominal strength). Fourteen of them contain dowels at the interface between old and new concrete. All columns were subjected to repeated (pseudo-seismic) axial compression with increasing deformation cycles up to failure with or without jacketing. Two load patterns were selected to examine the difference of the behavior of columns. The effects of the initial damages, of the reinforcement of the interface (dowels) and of the confinement generated by the stirrups are investigated through axial- deformation (slip) diagrams and the energy absorbed diagrams. The results indicate that the initial damages affect the total behavior of the column and the capacity of the interface to shear mechanisms and to slip: a) the maximum bearing load of old column is decreased affecting at the same time the loading capacity of the jacketed element, b) suitable repair of initially damaged specimens increases the capacity of the jacketed column to transfer load through the interface.

• Journal of Embryo Transfer
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• v.30 no.3
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• pp.201-206
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• 2015

Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Accumulating evidence indicates that Se compounds possess anticancer properties. Se is specifically incorporated into proteins in the form of selenocysteine and non-specifically incorporated as selenomethionine in place of methionine. This study evaluated protection by Se in the bone repair process in ovariectomized rats after irradiation. For such purpose, 80 ovariectomized female Sprague-Dawley rats were randomly divided into 4 experimental groups: ovariectomized (Ov), Ov/Se, Ov/irradiated (Irr) and Ov/ Se/Irr. A bone defect was created on the tibia of all animals 40 days after ovariectomy. Two days after surgery, only the Ov/Se and Ov/Se/Irr rats received 0.8 mg Se/kg. Three days after surgery, only the Ov/Irr and Ov/Se/Irr rats received 10 Gy of X-rays on the lower limb region. The animals were euthanized at 7, 15, 22 and 29 days after surgery to assess the repair process, which was evaluated by analysis of trabecular bone number (Masson Trichrome) and birefringence analysis (Picrosirius). It was possible to observe a delay in the bone repair process in the ovariectomized/irradiated group and similarity between the ovariectomized, Ov/ Se and Ov/Se/Irr groups. Our findings suggest that sodium selenite may influence a radioprotective effect in the bone repair of tibia of ovariectomized rats without toxicity.

• Structural Engineering and Mechanics
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• v.63 no.3
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• pp.361-370
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• 2017

Through the use of finite element analysis and acoustic emission techniques we have evaluated the interfacial failure of a carbon fiber reinforced polymer (CFRP) repair patch on a notched aluminum substrate. The repair of cracks is a very common and widely used practice in the aeronautics field to extend the life of cracked sheet metal panels. The process consists of adhesively bonding a patch that encompasses the notched site to provide additional strength, thereby increasing life and avoiding costly replacements. The mechanical strength of the bonded joint relies mainly on the bonding of the adhesive to the plate and patch stiffness. Stress concentrations at crack tips promote disbonding of the composite patch from the substrate, consequently reducing the bonded area, which makes this a critical aspect of repair effectiveness. In this paper we examine patch disbonding by calculating the influence of notch tip stress on disbond area and verify computational results with acoustic emission (AE) measurements obtained from specimens subjected to uniaxial tension. The FE results showed that disbonding first occurs between the patch and the substrate close to free edge of the patch followed by failure around the tip of the notch, both highest stress regions. Experimental results revealed that cement adhesion at the aluminum interface was the limiting factor in patch performance. The patch did not appear to strengthen the aluminum substrate when measured by stress-strain due to early stage disbonding. Analysis of the AE signals provided insight to the disbond locations and progression at the metal-adhesive interface. Crack growth from the notch in the aluminum was not observed until the stress reached a critical level, an instant before final fracture, which was unaffected by the patch due to early stage disbonding. The FE model was further utilized to study the effects of patch fiber orientation and increased adhesive strength. The model revealed that the effectiveness of patch repairs is strongly dependent upon the combined interactions of adhesive bond strength and fiber orientation.